BW171_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: BW171_H (Body weight QTL 171 (human)) Homo sapiens

Symbol: BW171_H
Name: Body weight QTL 171 (human)
RGD ID: 1643092
Trait: Body weight
Measurement Type: BMI
LOD Score: Not Available
P Value: 0.0014
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372025,882,684 - 51,882,684RGDGRCh37
Build 362025,316,105 - 51,316,105RGDNCBI36
Cross Type: Not Available
Population Stats: Caucasian and African American families ascertained through morbidly obese probands



Candidate Gene Status
ASIP is a candidate Gene for BW171_H
GNAS is a candidate Gene for BW171_H
CEBPB is a candidate Gene for BW171_H
HNF4A is a candidate Gene for BW171_H
MC3R is a candidate Gene for BW171_H
PCK1 is a candidate Gene for BW171_H

Disease Annotations     Click to see Annotation Detail View
obesity  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Genome scan for human obesity and linkage to markers in 20q13. Lee JH, etal., Am J Hum Genet. 1999 Jan;64(1):196-209.

Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Peak: (D20S107)
Human AssemblyChrPosition (strand)Source
GRCh372038,882,541 - 38,882,745UniSTS
GRCh372038,882,556 - 38,882,827UniSTS
Build 362038,315,970 - 38,316,241RGD
Celera2035,593,077 - 35,593,344RGD
Celera2035,593,062 - 35,593,262UniSTS
HuRef2035,620,943 - 35,621,210UniSTS
HuRef2035,620,928 - 35,621,128UniSTS
Marshfield Genetic Map2055.74RGD
Marshfield Genetic Map2055.74UniSTS
Genethon Genetic Map2054.9UniSTS
TNG Radiation Hybrid Map2018025.0UniSTS
deCODE Assembly Map2061.78UniSTS
Stanford-G3 RH Map202062.0UniSTS
GeneMap99-GB4 RH Map20224.7UniSTS
Whitehead-YAC Contig Map20 UniSTS
NCBI RH Map20361.8UniSTS
GeneMap99-G3 RH Map202095.0UniSTS


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general Study Method: detailed mapping of chromosome 20q 1642891
qtl_population Caucasian and African American families ascertained through morbidly obese probands 1642891
qtl_population_details 713 individuals from 124 nuclear families chosen on the basis of one member with BMI>=40; families include additional obese siblings (BMI>=30) and normal-weight sibs and parents (BMI<27) 1642891
qtl_statistics_details Software packages: single- and multi-point analyses using the EM algorithm-based Haseman-Elston regression (EMHE) implemented by MAPMAKER/SIBS v2.0 and nonparametric-linkage (NPL) implemented by GENEHUNTER v1.1; Also, an affecteds-only model using the FASTLINK version of MLINK and an affected-sibling-pair (ASP) analysis using SIBPAIR; additional analysis using only Cacasian individuals 1642891