Alcrsp16 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Alcrsp16 (Alcohol response QTL 16) Rattus norvegicus

Symbol: Alcrsp16
Name: Alcohol response QTL 16
RGD ID: 1641906
Previously known as: Blood ethanol concentration at regain of righting reflex; BECRR
Trait: alcohol metabolism trait   (VT:0015089)    
Measurement Type: blood ethanol level   (CMO:0000535)    
LOD Score: Likelihood Ratio: 17.3
P Value: Not Available
Variance: Not Available
Position No map positions available.
Cross Type: intercross
Strains Crossed: LAS1 HAS1 



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition
ethanol  (IDA)

Measurement Method

Vertebrate Trait

Rat Strain
HAS1  (IEA)
LAS1  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Quantitative trait Loci mapping for ethanol sensitivity and neurotensin receptor density in an F2 intercross derived from inbred high and low alcohol sensitivity selectively bred rat lines. Radcliffe RA, etal., Alcohol Clin Exp Res 2004 Dec;28(12):1796-804.
2. Confirmation of quantitative trait loci for ethanol sensitivity and neurotensin receptor density in crosses derived from the inbred high and low alcohol sensitive selectively bred rat lines. Radcliffe RA, etal., Psychopharmacology (Berl). 2006 Oct;188(3):343-54. Epub 2006 Sep 5.

Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch

Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general number of animals used: 450 rats inducing agent: intraperitoneal administration of alcohol 3.5 g/kg 1600610
qtl_general measurement method: mean blood ethanol concentration from two 40 microliter retro-orbital blood samples 1600610
qtl_general software package used: Map Manager QTX 1600610
qtl_general allele responsible: HAS allele caused lower BECRR in males than in females 1600610
qtl_statistics Likelihood Ratio: 17.3 1600610