Eae22 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Eae22 (Experimental allergic encephalomyelitis QTL 22) Rattus norvegicus

Symbol: Eae22
Name: Experimental allergic encephalomyelitis QTL 22
RGD ID: 1581561
Trait: nervous system integrity trait   (VT:0010566)    
Measurement Type: post-insult time to onset of experimental autoimmune encephalomyelitis   (CMO:0001422)    
LOD Score: Not Available
P Value: Not Available
Variance: Not Available
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.04190,919,460 - 235,919,460RGDRnor5.0
RGSC_v3.44145,746,752 - 187,126,005RGDRGSC3.4
RGSC_v3.14145,991,688 - 187,371,129RGD
Cross Type: Not Available
Strains Crossed: DA PVG.1AV1 

Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
post-insult time to onset of experimental autoimmune encephalomyelitis  IDA 1547849 RGD 

Experimental Condition
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
Freund's incomplete adjuvant  IDA 1547849 RGD 
myelin oligodendrocyte glycoprotein  IDA 1547849 RGD 

Measurement Method
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
in vivo visual assessment  IDA 1547849 RGD 

Rat Strain
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
DA  IEA 1547849 RGD 
PVG.1AV1  IEA 1547849 RGD 

Vertebrate Trait
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
nervous system integrity trait  IDA 1547849 RGD 

Disease Annotations     Click to see Annotation Detail View

Experimental Data Annotations     Click to see Annotation Detail View

Measurement Method

Vertebrate Trait

Rat Strain


References - curated
# Reference Title Reference Citation
1. Resolution of a 16.8-Mb autoimmunity-regulating rat chromosome 4 region into multiple encephalomyelitis quantitative trait loci and evidence for epistasis. Jagodic M, etal., J Immunol 2005 Jan 15;174(2):918-24.


Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Peak: (D4Got135)
Rat AssemblyChrPosition (strand)Source
Rnor_5.04213,419,595 - 213,419,846UniSTS
Rnor_5.04213,419,074 - 213,419,846UniSTS
RGSC_v3.44168,246,626 - 168,246,878RGD
RGSC_v3.44168,246,627 - 168,246,878UniSTS
RGSC_v3.14168,491,562 - 168,491,814RGD
Celera4153,047,193 - 153,047,444UniSTS
RH 3.4 Map41013.4UniSTS
RH 3.4 Map41013.4RGD
Cytogenetic Map4q42UniSTS

Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general region confirmed by the development of DA.PVG.1AV1-(D4Rat63-D4Rat203) congenic strain 1547849
qtl_statistics_details QTL displays epistatic interaction with Eae20 PVG alleles in congenic strain DA.PVG.1AV1-(D4Rat63-D4Rat203) 1547849