Kidm69 QTL Report (Rattus norvegicus) - Rat Genome Database
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QTL: Kidm69 (Kidney mass QTL 69) Rattus norvegicus

Symbol: Kidm69
Name: Kidney mass QTL 69
RGD ID: 12903955
Also known as: BpcaKmC16QTL
Trait: kidney mass   (VT:0002707)    
Measurement Type: both kidneys wet weight to body weight ratio   (CMO:0000340)    
LOD Score: Not Available
P Value: 0.001
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0161,550,330 - 5,013,802RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0161,534,551 - 4,954,192RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.416819,369 - 4,304,396RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: SS.LEW-(D16Got3-D16Rat112)/Ayd 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
hypertension  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait
kidney mass  (IDA)

Rat Strain

References

References - curated
1. Duong C, etal., Mamm Genome. 2006 Dec;17(12):1147-61. Epub 2006 Dec 1.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
69250Wnt5aWnt family member 5A1644694514490271Rat
628670Ppifpeptidylprolyl isomerase F1619791911985912Rat
621275Arf4ADP-ribosylation factor 41623383332354909Rat
619990Dnah12dynein, axonemal, heavy chain 121623772182534130Rat
708372Erc2ELKS/RAB6-interacting/CAST family member 21632585804283592Rat
631361Cacna2d3calcium voltage-gated channel auxiliary subunit alpha2delta 31648713485795825Rat
1309388Appl1adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 11625601032602035Rat
1305689Tmem254transmembrane protein 2541638174023821270Rat
1306662Plac9placenta associated 91638511073866008Rat
1309911Anxa11annexin A111638671933912043Rat
1310975Pde12phosphodiesterase 121623570282367069Rat
1306164Zcchc24zinc finger CCHC-type containing 241619965402048292Rat
1307674Slmapsarcolemma associated protein1621122712227336Rat
1311620Zmiz1zinc finger, MIZ-type containing 11617491911954633Rat
1306064Dennd6aDENN domain containing 6A1622787012327062Rat
1310672Arhgef3Rho guanine nucleotide exchange factor 31627437143026768Rat
1563858Hesx1HESX homeobox 11626165382636708Rat
1560873Ccdc66coiled-coil domain containing 661631071193139188Rat
1311053Dux4double homeobox 41637549683766532Rat
1565219Cphx1cytoplasmic polyadenylated homeobox 11637871413796715Rat
1565017RGD1565017similar to RS21-C6 protein1639353743936145Rat
1565237Il17rdinterleukin 17 receptor D1626704712737271Rat
1595469Tasortranscription activation suppressor1630505063108168Rat
1596812Asb14ankyrin repeat and SOCS box-containing 141625372092556930Rat
2322864LOC100360083ribosomal protein L5-like1647013654703408Rat
2321691Lrtm1leucine-rich repeats and transmembrane domains 11649937285005110Rat
6491687LOC100911661uncharacterized LOC1009116611636922363701658Rat
6502340LOC100909673protein FAM173B-like1631904563191172Rat
7489016Mir3075microRNA 30751618228051822917Rat
7515318LOC102553299uncharacterized LOC1025532991620551292056443Rat
7511720LOC102547893uncharacterized LOC1025478931623830902387269Rat
7636032LOC102553896MLV-related proviral Env polyprotein-like1631639193172785Rat
7627458LOC102553231uncharacterized LOC1025532311617191851739683Rat
7571795LOC102553140uncharacterized LOC1025531401617495281752476Rat
7556606LOC102548056uncharacterized LOC1025480561627423932744017Rat
7546544LOC102554645uncharacterized LOC1025546451650122595029718Rat
7695236LOC102548123uncharacterized LOC1025481231631107213114360Rat
7668173LOC102553494aconitate hydratase, mitochondrial-like1633502133355021Rat
7728594LOC102547798protein phosphatase 1 regulatory subunit 26-like1624628982467111Rat
9134190LOC103693956uncharacterized LOC1036939561649833884985193Rat
9099868LOC103693861uncharacterized LOC1036938611616961231703369Rat
9109796LOC103693871host cell factor C1 regulator 1-like1625660492567713Rat
9247050LOC103693862U6 snRNA-associated Sm-like protein LSm5 pseudogene1620615902061900Rat
9261783LOC103693874cyclin-dependent kinases regulatory subunit 2 pseudogene1641622124165547Rat
9302900LOC103693877PRAME family member 12 pseudogene1633965063403820Rat
9442066LOC103693876uncharacterized LOC1036938761644472064458282Rat
11466711LOC108353069uncharacterized LOC1083530691623677292370312Rat
11444877LOC108353109uncharacterized LOC1083531091635875793591751Rat
11356963LOC108353110uncharacterized LOC1083531101649478585031021Rat
11448061LOC10835308860S ribosomal protein L27 pseudogene1619619041964674Rat
11422894LOC108348452uncharacterized LOC1083484521633438343382963Rat
11425421LOC108353065uncharacterized LOC1083530651615501391558969Rat
11390250LOC108353070uncharacterized LOC1083530701628282472829609Rat
11485626LOC108353089uncharacterized LOC1083530891639122493916050Rat
11486017LOC108353068uncharacterized LOC1083530681621067832113069Rat
11487618LOC10835306760S ribosomal protein L34 pseudogene1622052272209399Rat
11491910LOC108353066uncharacterized LOC1083530661618839871894922Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
33848D16Mit21691650138025013922Ratregion
35831D16Rat221781642096544209831Ratregion
40724D16Rat872071641363554136567Ratregion
38784D16Rat512421641475084147729Ratregion
39456D16Rat881481615501871550330Ratregion
45309D16Got32691642031044203372Ratregion
45311D16Got61231637474053747527Ratregion
66387D16Mco34001646987434699195Ratregion
1357995D16Chm682451624700472470291Ratregion
1357996D16Chm651841632894163289599Ratregion
1358001D16Chm712491626862012686449Ratregion
1358002D16Chm732231625154562515678Ratregion
1358003D16Chm611901640659354066124Ratregion
1358004D16Chm492131641927614192973Ratregion
1358005D16Chm272071628901992890405Ratregion
1358006D16Chm161811629971722997352Ratregion
1358007D16Chm781581630730493073206Ratregion
1358010D16Chm432001629714472971646Ratregion
1358015D16Chm672401626500932650332Ratregion
1358017D16Chm642501632488513249100Ratregion
1358025D16Chm772411630484023048642Ratregion
1358026D16Chm742171621828332183049Ratregion
1358032D16Chm692371624359422436149Ratregion
1358034D16Chm632381632964513296688Ratregion
1358035D16Chm471981626786642678861Ratregion
1358040D16Chm362161616198351620050Ratregion
1358041D16Chm602611635249573525217Ratregion
1358042D16Chm662381634395253439762Ratregion
1358043D16Chm292721623720002372271Ratregion
1358044D16Chm22081631273853127592Ratregion
1358046D16Chm762481630278323028079Ratregion
1358047D16Chm412651629124152912678Ratregion
1358053D16Chm462001623081242308323Ratregion
1631551D16Got1202791634642623464540Ratregion
1628998D16Got1232861648651714865449Ratregion
1640551D16Got1243001624291282429426Ratregion
1637378D16Got1161081642136784213785Ratregion
7206794RH12464116211638499413851561Ratregion
5039282RH1276161851619541741954358Ratregion
5037191RH989471521621135842113735Ratregion
5028641RH1257292471623546092354855Ratregion
5028733Cda0je041061644457824445887Ratregion
5031728AU0473471451616175491617693Ratregion
5034363D3S31152681644457754446042Ratregion
5034952AI1802021571619483691948525Ratregion
5032765RH1352171811636355423635722Ratregion
5033495RH1390412101644454564445665Ratregion
5028303DXMit1071881616762331676420Ratregion
5033801RH1401741971625567762556972Ratregion
5056533RH1444332591640927614093019Ratregion
5054209RH1430931721643709004371071Ratregion
5054741RH1433981051619524961952600Ratregion
5055653RH1439251171639123623912478Ratregion
5052281MDB03321651644884684488632Ratregion
5051186RH1344892051638209183821122Ratregion
5054717RH1433852661616812761681541Ratregion
5054861RH1434671091638883553888463Ratregion
5045196RH1310392081627368912737098Ratregion
5048778RH1331001961636924523692647Ratregion
5045502RH1312152171631159763116192Ratregion
5046840RH1319852201618638351864054Ratregion
5046918RH1320292071617521891752395Ratregion
5042232RH1293161651623546212354785Ratregion
5039664RH1278351951631077193107913Ratregion
5042798RH1296521931623546952354887Ratregion
5040416RH1282712051619855771985781Ratregion
5039818RH1279242061623617382361943Ratregion
7192161Hesx15961626358822636477Ratregion
5040234RH1281662181631072963107513Ratregion
5042566RH1295121871625602702560456Ratregion
5041120RH1286741851638672573867441Ratregion
5075948RH1388901781629332132933392Ratregion
5077552RH1398212091625631302563338Ratregion
5079912RH1412742121637550213755232Ratregion
5073128RH1372542201639358063936025Ratregion
5073174RH1372821831620617442061923Ratregion
5061822AW5337311911623380872338277Ratregion
5066700AU0482021301622657342265860Ratregion
5066870AU0481022131648931904893402Ratregion
5067358AU0478031781617715391771716Ratregion
5060804AI1452022011644457144445914Ratregion
5062866BE1131071601644899854490144Ratregion
5064622BF3994591561644880424488197Ratregion
5066140BF4135831041630961013096204Ratregion
5061526BE1119621511623555622355712Ratregion
5061536BF3966532141644681704468383Ratregion
5061542AA8754122101621131272113336Ratregion
5082325BE1191951611642219324222092Ratregion
5082363BE1192581561623058652306020Ratregion
5088145Wnt5a1891644859924486180Ratregion
5089497AU0491902391618479501848188Ratregion
5088881AU0488251901644522114452400Ratregion
5088147Wnt5a2211644859924486212Ratregion
5086028AA8591561951619541651954359Ratregion
5084846AI2359011121623262082326319Ratregion
5084934AA8002851011621030512103151Ratregion
5083203BI2753041661628843012884466Ratregion
5085597AW5281802261643025544302779Ratregion
5503346Hesx101626349772635894Ratregion
5506577Wnt5a2341644754474476866Ratregion
5501892MARC_17013-17014:1023291181:101621633192163741Ratregion
Position Markers

Flank 1: (D16Mit2)
Rat AssemblyChrPosition (strand)Source
Rnor_6.0165,013,802 - 5,013,922NCBI
Rnor_6.0165,098,584 - 5,098,704NCBI
Rnor_5.0164,954,192 - 4,954,312UniSTS
Rnor_5.0165,038,686 - 5,038,806UniSTS
RGSC_v3.4164,304,396 - 4,304,517RGD
RGSC_v3.4164,304,397 - 4,304,517UniSTS
RGSC_v3.1164,304,394 - 4,304,515RGD
Celera1610,945,533 - 10,945,653UniSTS
Cytogenetic Map16p16UniSTS
RH 3.4 Map168.3UniSTS
RH 3.4 Map168.3RGD
SHRSP x BN Map161.1599UniSTS
SHRSP x BN Map161.1599RGD
FHH x ACI Map163.1999RGD
Flank 2: (D16Rat88)
Rat AssemblyChrPosition (strand)Source
Rnor_6.0161,550,187 - 1,550,330NCBI
Rnor_5.0161,534,408 - 1,534,551UniSTS
RGSC_v3.416819,225 - 819,369RGD
RGSC_v3.416819,226 - 819,369UniSTS
RGSC_v3.116819,226 - 819,369RGD
Celera16812,123 - 812,266UniSTS
RH 3.4 Map18655.3UniSTS
RH 3.4 Map18655.3RGD
RH 2.0 Map18257.7RGD
SHRSP x BN Map161.1999RGD


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2325838Bp347Blood pressure QTL 3470.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1613525217Rat
1357403Slep4Serum leptin concentration QTL 43.91blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16110660736Rat
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16124228366Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16127556253Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16127556253Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16127556253Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16131816439Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16133160624Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16134465490Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16141240937Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16141240937Rat
631561Hcuc2Hepatic copper content QTL 22.8hepatic copper amount (VT:0003065)liver total copper weight (CMO:0001507)16141240957Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)1624459345244593Rat
1549842Bp248Blood pressure QTL 2480.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1610900543439762Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)16109005486162972Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16134074146340741Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)16155018749247447Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)16155018763210301Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16155018763210301Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)16155018763210301Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)16155018763210301Rat
2301404Bp321Blood pressure QTL 3210.05arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1615503303439525Rat
12903278Am16Aortic mass QTL 160.019aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1615503303439525Rat
12903279Cm115Cardiac mass QTL 1150.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)1615503303439525Rat
12903281Cm116Cardiac mass QTL 1160.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)1615503303439525Rat
12903952Cm117Cardiac mass QTL 1170.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)1615503303439525Rat
12903954Bw186Body weight QTL 1860.011body mass (VT:0001259)body weight (CMO:0000012)1615503303439525Rat
12903955Kidm69Kidney mass QTL 690.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1615503305013802Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16172829746728297Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)16329668817464293Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16413635523105837Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16413635545905331Rat
737825Alc13Alcohol consumption QTL 134.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16501380218360147Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)16501380245905331Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16501380245905331Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16501380245905331Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16501380250013802Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16501380250169318Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16501380252144919Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16501380264012784Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general number of animals used: 9 gender: male 1599557
qtl_general also affects heart mass, heart right and left ventricle mass, aortic mass, body mass and blood pressure 1599557
qtl_statistics_details software package used: ANOVA followed by Dunnett test in the SYSTAT 9 program 1599557
qtl_trait_method measurement method: selected males were weaned at 21 days of age then fed 2% NaCl diet starting from 35 days of age, at 14 weeks animals were decapitated, organs removed, blotted and weighed 1599557
 



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.