Bss121 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bss121 (Bone structure and strength QTL 121) Rattus norvegicus

Symbol: Bss121
Name: Bone structure and strength QTL 121
RGD ID: 11528640
Trait: femur morphology trait   (VT:0000559)    
Measurement Type: femur length   (CMO:0000442)    
LOD Score: 6.72
P Value: 1.9E-7
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22033,221,477 - 35,747,124RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.02035,276,651 - 37,867,728RGD_MAPPER_PIPELINERnor6.0
Rnor_5.02037,033,030 - 39,603,228RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.42032,600,592 - 35,400,884RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: NAft:HS 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement
femur length  (IDA)

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
NAft:HS  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Fine mapping of bone structure and strength QTLs in heterogeneous stock rat. Alam I, etal., Bone. 2015 Dec;81:417-26. doi: 10.1016/j.bone.2015.08.013. Epub 2015 Aug 19.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1310891Man1a1mannosidase, alpha, class 1A, member 1203320250933385747Rat
1559810Cd46l1CD46 molecule like 1203399640433997405Rat
1589355Tuba1b-ps10tubulin, alpha 1B, pseudogene 10203407129034072085Rat
1566244Tatdn1-ps1TatD DNase domain containing 1, pseudogene 1203445576234456682Rat
41393454LOC120099027small nucleolar RNA SNORA17203468475734684858Rat
1595968Rab1a-ps5RAB1A, member RAS oncogene family, pseudogene 5203468878734689383Rat
2323599Tbc1d32TBC1 domain family, member 32203535986535590992Rat
41083251Ube2n-ps7ubiquitin-conjugating enzyme E2N, pseudogene 7203538987935390578Rat
1308699Msl3l2male-specific lethal 3-like 2203546887735477025Rat
9266578LOC103694462inactive serine/threonine-protein kinase VRK3 pseudogene203573191735732340Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
35327D20Rat10158203425743634257594Ratregion
36785D20Rat12160203349793633498097Ratregion
40366D20Rat52173203527228935272448Ratregion
38762D20Rat40210203440214934402348Ratregion
41550D20Rat53145203511737135117517Ratregion
43146D20Rat76248203327829533278545Ratregion
45695D20Got35235203507309335073328Ratregion
67239D20Arb9362203507297135073333Ratregion
5028119D10Mit257.1236203551006635510302Ratregion
5059268BF387907174203324285433243028Ratregion
5045810RH131392211203547670035476911Ratregion
5047030RH132094211203379829033798501Ratregion
5080184RH141433218203551556435515782Ratregion
5066612AU048254150203388131733881467Ratregion
5068390AU047175170203509070235090897Ratregion
5068390AU047175170203509072735090897Ratregion
5089303AU049075298203553560335535902Ratregion
11528637rs105739537203445040234450402Ratregion
11528638rs197893447203322147733221477Ratregion
11528639rs105033786203574712435747124Ratregion
Position Markers

Flank 1: (rs197893447)
Rat AssemblyChrPosition (strand)Source
mRatBN7.22033,221,477 - 33,221,477RGD
Rnor_6.02035,276,651 - 35,276,651RGD
Peak: (rs105739537)
Rat AssemblyChrPosition (strand)Source
mRatBN7.22034,450,402 - 34,450,402RGD
Rnor_6.02036,528,644 - 36,528,644RGD
Flank 2: (rs105033786)
Rat AssemblyChrPosition (strand)Source
mRatBN7.22035,747,124 - 35,747,124RGD
Rnor_6.02037,867,728 - 37,867,728RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)201761783247606836Rat
2303587Bw93Body weight QTL 9313body mass (VT:0001259)body weight (CMO:0000012)202510672254435887Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
2303626Vencon10Ventilatory control QTL 100.001respiration trait (VT:0001943)respiration rate (CMO:0000289)201919072154435887Rat
1598869Memor6Memory QTL 63.1exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)202924438854435887Rat
70158Bp60Blood pressure QTL 603arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)203161428444396023Rat
11528640Bss121Bone structure and strength QTL 1216.722e-07femur morphology trait (VT:0000559)femur length (CMO:0000442)203322147735747124Rat
7411652Foco24Food consumption QTL 240.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)201175751554435887Rat
1331747Hrtrt16Heart rate QTL 163.163heart pumping trait (VT:2000009)heart rate (CMO:0000002)202520973454435887Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
2303578Gluco50Glucose level QTL 502blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)202510672254435887Rat
2317880Alcrsp25Alcohol response QTL 252.3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)201769755054435887Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
9590092Insglur9Insulin/glucose ratio QTL 918.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)201175751554435887Rat
2300188Bmd68Bone mineral density QTL 686.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)202510672254435887Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general number of animals used: 1524 HS rats (728 male, 796 female) were used. 11528619
qtl_general measurement method: Rats on a standard diet were euthanized at 17 to 20 weeks of age, and left femurs were measured using digital calipers (Mitutoyo, Aurora, IL). 11528619