Gene: RT1-DMb (RT1 class II, locus DMb) Rattus norvegicus
Symbol: RT1-DMb
Name: RT1 class II, locus DMb
Description: ENCODES a protein that exhibits MHC class II protein complex binding (ortholog); INVOLVED IN antigen processing and presentation (ortholog); antigen processing and presentation of exogenous peptide antigen via MHC class II (ortholog); chaperone cofactor-dependent protein refolding (ortholog); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; asthma pathway; ASSOCIATED WITH Experimental Liver Cirrhosis; FOUND IN endosome membrane (ortholog); integral component of membrane (ortholog); late endosome (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 3,3',5,5'-tetrabromobisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DMb; Hla-dmb; major histocompatibility complex, class II, DM beta; MHC class II-like beta chain; RT1 class II, DM beta; RT1.DMb; RT1.Mb
Is Marker For: Strains:   DA.AS2-(Tesb-RT1-DMb)   DA.KHW-(RT1-Db1-RT1-DMb)   DA.E3-(Btnl2-RT1-DMb)  
QTLs:   Tcs2  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0203,945,383 - 3,952,838 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0207,288,114 - 7,295,355 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,829,535 - 4,836,772 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1204,829,762 - 4,836,902 (-)NCBI
Celera206,293,763 - 6,301,000 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on RT1-DMb
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735096
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2018-08-08
Status: ACTIVE