RT1-DMa (RT1 class II, locus DMa) - Rat Genome Database

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Gene: RT1-DMa (RT1 class II, locus DMa) Rattus norvegicus
Analyze
Symbol: RT1-DMa
Name: RT1 class II, locus DMa
RGD ID: 735053
Description: Predicted to enable MHC class II protein complex binding activity. Predicted to be involved in peptide antigen assembly with MHC class II protein complex; positive regulation of germinal center formation; and positive regulation of humoral immune response. Predicted to act upstream of or within several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II; chaperone cofactor-dependent protein refolding; and positive thymic T cell selection. Predicted to be located in cell surface; late endosome; and lysosomal membrane. Predicted to be part of MHC class II protein complex. Orthologous to human HLA-DMA (major histocompatibility complex, class II, DM alpha); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; asthma pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: class II histocompatibility antigen, M alpha chain; DMA1; Hla-dma; LOC108348072; major histocompatibility complex, class II, DM alpha; MHC class II-like alpha chain; RT1 class II, DM alpha; RT1.DMa; RT1.Ma
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Is Marker For: Strains:   DA.E3-(RT1-DMa-Ggnbp1)   DA.KHW-(RT1-DMa-Mln)  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,708,932 - 4,712,335 (-)NCBIGRCr8
mRatBN7.2204,707,028 - 4,710,432 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,707,028 - 4,710,432 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx205,459,571 - 5,462,978 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0204,821,312 - 4,824,719 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0205,302,578 - 5,305,996 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0203,935,512 - 3,938,915 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,240,975 - 5,244,386 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,302,036 - 7,305,439 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,843,458 - 4,846,861 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1204,843,691 - 4,847,054 (-)NCBI
Celera206,307,688 - 6,311,091 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (ISO)
2-hydroxypropanoic acid  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
alachlor  (EXP)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP,ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
coumarin  (EXP)
cyclosporin A  (ISO)
D-glucose  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diethylstilbestrol  (ISO)
diquat  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
fonofos  (ISO)
fructose  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
glucose  (ISO)
glyphosate  (ISO)
hexachlorobenzene  (EXP)
isoprenaline  (ISO)
lead(0)  (ISO)
mercury dibromide  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
N-nitrosomorpholine  (EXP)
nickel sulfate  (ISO)
omeprazole  (ISO)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (EXP)
rifampicin  (ISO)
SB 431542  (ISO)
silicon dioxide  (EXP,ISO)
simvastatin  (EXP)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
Soman  (EXP)
streptozocin  (EXP)
sulforaphane  (ISO)
tamibarotene  (ISO)
temozolomide  (ISO)
terbufos  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
Triptolide  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zoledronic acid  (ISO)

References

References - curated
# Reference Title Reference Citation
1. The impact of H2-DM on humoral immune responses. Alfonso C, etal., J Immunol 2001 Dec 1;167(11):6348-55.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. HLA-DMA and HLA-DMB genotyping in patients with rheumatic diseases. Yen JH, etal., Kaohsiung J Med Sci. 1999 May;15(5):263-7.
8. Integrated Analysis of Multiple Microarray Studies to Identify Core Gene-Expression Signatures Involved in Tubulointerstitial Injury in Diabetic Nephropathy. Zhou H, etal., Biomed Res Int. 2022 May 10;2022:9554658. doi: 10.1155/2022/9554658. eCollection 2022.
Additional References at PubMed
PMID:7584146   PMID:7590989   PMID:7606781   PMID:7985028   PMID:8598040   PMID:8598041   PMID:8638109   PMID:8890155   PMID:9432982   PMID:9492004   PMID:11027433   PMID:11148202  
PMID:11685465   PMID:11854359   PMID:12477932   PMID:16435885   PMID:19691639   PMID:19946888   PMID:21795542   PMID:22247549   PMID:22733780   PMID:23376485   PMID:24586191  


Genomics

Comparative Map Data
RT1-DMa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,708,932 - 4,712,335 (-)NCBIGRCr8
mRatBN7.2204,707,028 - 4,710,432 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,707,028 - 4,710,432 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx205,459,571 - 5,462,978 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0204,821,312 - 4,824,719 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0205,302,578 - 5,305,996 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0203,935,512 - 3,938,915 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,240,975 - 5,244,386 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,302,036 - 7,305,439 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,843,458 - 4,846,861 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1204,843,691 - 4,847,054 (-)NCBI
Celera206,307,688 - 6,311,091 (-)NCBICelera
Cytogenetic Map20p12NCBI
HLA-DMA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38632,948,618 - 32,953,097 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl632,948,613 - 32,969,094 (-)EnsemblGRCh38hg38GRCh38
GRCh37632,916,395 - 32,920,874 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36633,024,373 - 33,028,831 (-)NCBINCBI36Build 36hg18NCBI36
Build 34633,024,373 - 33,028,831NCBI
Celera634,465,294 - 34,469,805 (-)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef632,658,920 - 32,663,431 (-)NCBIHuRef
CHM1_1632,917,186 - 32,921,697 (-)NCBICHM1_1
T2T-CHM13v2.0632,769,955 - 32,774,437 (-)NCBIT2T-CHM13v2.0
H2-DMa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,338,667 - 34,358,075 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1734,338,515 - 34,358,075 (+)EnsemblGRCm39 Ensembl
GRCm381734,119,693 - 34,139,101 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,119,541 - 34,139,101 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,272,616 - 34,275,480 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361733,746,082 - 33,749,555 (+)NCBIMGSCv36mm8
Celera1736,887,536 - 36,890,397 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
LOC102023843
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554371,558,911 - 1,562,162 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554371,558,806 - 1,562,294 (-)NCBIChiLan1.0ChiLan1.0
LOC100968989
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2547,423,704 - 47,428,283 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1643,295,262 - 43,299,831 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0632,518,060 - 32,537,989 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1633,633,497 - 33,639,091 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl633,634,123 - 33,637,988 (-)Ensemblpanpan1.1panPan2
LOC101963772
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494638,120,076 - 38,124,109 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647625,836,142 - 25,840,197 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647625,836,163 - 25,840,191 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLA-DMA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl725,133,497 - 25,137,966 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1725,133,494 - 25,137,928 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2729,500,103 - 29,504,572 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap7q1.1NCBI
MHC-DMA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11739,142,340 - 39,151,804 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1739,142,395 - 39,146,252 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604432,737,022 - 32,757,552 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101700274
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475423,762,051 - 23,765,593 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475423,752,352 - 23,765,319 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RT1-DMa
72 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:236
Count of miRNA genes:123
Interacting mature miRNAs:139
Transcripts:ENSRNOT00000070886, ENSRNOT00000072458
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015279595304575Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2036216499243559Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)20362164910078919Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20362165614101050Rat
61474Eae1Experimental allergic encephalomyelitis QTL 13nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)2046066076691706Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20460660717617956Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20460660717617956Rat


Related Rat Strains
The following Strains have been annotated to RT1-DMa


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 1 2
Below cutoff 4 2 7 1 4 3 1 5

Sequence


RefSeq Acc Id: ENSRNOT00000070886   ⟹   ENSRNOP00000066343
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl204,707,029 - 4,710,432 (-)Ensembl
Rnor_6.0 Ensembl205,240,975 - 5,244,386 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000072458   ⟹   ENSRNOP00000067364
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl204,707,029 - 4,710,292 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000078036   ⟹   ENSRNOP00000093448
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl204,707,028 - 4,710,432 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000078382
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl205,242,322 - 5,244,330 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000080583
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl204,707,028 - 4,710,017 (-)Ensembl
Rnor_6.0 Ensembl205,240,975 - 5,241,496 (-)Ensembl
RefSeq Acc Id: NM_198741   ⟹   NP_942036
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8204,708,932 - 4,712,335 (-)NCBI
mRatBN7.2204,707,028 - 4,710,432 (-)NCBI
Rnor_6.0203,935,512 - 3,938,915 (+)NCBI
Rnor_5.0207,302,036 - 7,305,439 (-)NCBI
RGSC_v3.4204,843,458 - 4,846,861 (-)RGD
Celera206,307,688 - 6,311,091 (-)RGD
Sequence:
RefSeq Acc Id: NP_942036   ⟸   NM_198741
- Peptide Label: precursor
- UniProtKB: Q95574 (UniProtKB/TrEMBL),   A6JJE8 (UniProtKB/TrEMBL),   A0A8I6AFU3 (UniProtKB/TrEMBL),   A0A023IKC6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000066343   ⟸   ENSRNOT00000070886
RefSeq Acc Id: ENSRNOP00000093448   ⟸   ENSRNOT00000078036
RefSeq Acc Id: ENSRNOP00000067364   ⟸   ENSRNOT00000072458
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q95574-F1-model_v2 AlphaFold Q95574 1-260 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701324
Promoter ID:EPDNEW_R11844
Type:multiple initiation site
Name:LOC108348072_1
Description:class II histocompatibility antigen, M alpha chain
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0203,935,546 - 3,935,606EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735053 AgrOrtholog
BioCyc Gene G2FUF-4550 BioCyc
Ensembl Genes ENSRNOG00000047864 Ensembl
  ENSRNOG00000066773 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000070886 ENTREZGENE
  ENSRNOT00000070886.3 UniProtKB/TrEMBL
  ENSRNOT00000072458.3 UniProtKB/TrEMBL
  ENSRNOT00000078036.2 UniProtKB/TrEMBL
  ENSRNOT00000080583.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7377707 IMAGE-MGC_LOAD
InterPro Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/TrEMBL
  MHC_I/II-like_Ag-recog UniProtKB/TrEMBL
  MHC_II_a/b_N UniProtKB/TrEMBL
  MHC_II_a_N UniProtKB/TrEMBL
KEGG Report rno:294274 UniProtKB/TrEMBL
MGC_CLONE MGC:108532 IMAGE-MGC_LOAD
NCBI Gene 294274 ENTREZGENE
PANTHER HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DM ALPHA CHAIN UniProtKB/TrEMBL
  MHC CLASS II-RELATED UniProtKB/TrEMBL
Pfam C1-set UniProtKB/TrEMBL
  MHC_II_alpha UniProtKB/TrEMBL
PhenoGen RT1-DMa PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
  IG_MHC UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047864 RatGTEx
  ENSRNOG00000066773 RatGTEx
SMART IGc1 UniProtKB/TrEMBL
  MHC_II_alpha UniProtKB/TrEMBL
Superfamily-SCOP MHC_I/II-like_Ag-recog UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt A0A023IKC6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AFU3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AIM7_RAT UniProtKB/TrEMBL
  A6JJE8 ENTREZGENE
  M0RCN9_RAT UniProtKB/TrEMBL
  Q95574 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A6JJE8 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 RT1-DMa  RT1 class II, locus DMa  LOC108348072  class II histocompatibility antigen, M alpha chain  Data merged from RGD:11505944 737654 PROVISIONAL
2016-08-02 LOC108348072  class II histocompatibility antigen, M alpha chain      Symbol and Name status set to provisional 70820 PROVISIONAL
2009-09-14 RT1-DMa  RT1 class II, locus DMa  Hla-dma  major histocompatibility complex, class II, DM alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Hla-dma  major histocompatibility complex, class II, DM alpha      Symbol and Name status set to approved 1299863 APPROVED
2005-09-30 Hla-dma        Symbol and Name status set to provisional 70820 PROVISIONAL