Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Sgpp1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SGPP1 mRNA | CTD | PMID:36331819 | (S)-nicotine | decreases expression | ISO | Sgpp1 (Mus musculus) | 6480464 | Nicotine results in decreased expression of SGPP1 mRNA | CTD | PMID:17997037 | 1,2-dimethylhydrazine | multiple interactions | ISO | Sgpp1 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of SGPP1 mRNA] | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | ISO | Sgpp1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SGPP1 mRNA | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of SGPP1 mRNA | CTD | PMID:26496021 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of SGPP1 mRNA | CTD | PMID:32145629 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Sgpp1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SGPP1 mRNA | CTD | PMID:18796159 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SGPP1 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SGPP1 mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Sgpp1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SGPP1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | SGPP1 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SGPP1 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SGPP1 mRNA | CTD | PMID:21215274 and PMID:33387578 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of SGPP1 mRNA | CTD | PMID:21346803 | 2-butoxyethanol | increases expression | ISO | Sgpp1 (Mus musculus) | 6480464 | n-butoxyethanol results in increased expression of SGPP1 mRNA | CTD | PMID:19812364 | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of SGPP1 mRNA | CTD | PMID:28522335 | 4,4'-diaminodiphenylmethane | increases expression | ISO | Sgpp1 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of SGPP1 mRNA | CTD | PMID:18648102 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Sgpp1 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of SGPP1 mRNA | CTD | PMID:28973697 | 4-hydroxyphenyl retinamide | increases expression | ISO | Sgpp1 (Mus musculus) | 6480464 | Fenretinide results in increased expression of SGPP1 mRNA | CTD | PMID:28973697 | aflatoxin B1 | increases methylation | ISO | SGPP1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of SGPP1 gene | CTD | PMID:27153756 | all-trans-retinoic acid | affects expression | ISO | Sgpp1 (Mus musculus) | 6480464 | Tretinoin affects the expression of SGPP1 mRNA | CTD | PMID:34627992 | all-trans-retinoic acid | multiple interactions | ISO | Sgpp1 (Mus musculus) | 6480464 | 3 and 3'-dichlorobiphenyl affects the reaction [Tretinoin affects the expression of SGPP1 mRNA] | CTD | PMID:34627992 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of SGPP1 mRNA | CTD | PMID:16483693 | benzo[a]pyrene | increases expression | ISO | Sgpp1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of SGPP1 mRNA | CTD | PMID:15034205 | benzo[a]pyrene | multiple interactions | ISO | Sgpp1 (Mus musculus) | 6480464 | AHR protein inhibits the reaction [Benzo(a)pyrene results in increased expression of SGPP1 mRNA] | CTD | PMID:15034205 | bilirubin IXalpha | decreases expression | ISO | SGPP1 (Homo sapiens) | 6480464 | Bilirubin results in decreased expression of SGPP1 mRNA | CTD | PMID:20196124 | bis(2-ethylhexyl) phthalate | increases expression | ISO | SGPP1 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of SGPP1 mRNA | CTD | PMID:31163220 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of SGPP1 mRNA | CTD | PMID:26496021 | bisphenol A | decreases expression | ISO | Sgpp1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of SGPP1 mRNA | CTD | PMID:33221593 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of SGPP1 mRNA | CTD | PMID:32145629 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SGPP1 mRNA | CTD | PMID:25181051 and PMID:30816183 | bortezomib | increases expression | ISO | SGPP1 (Homo sapiens) | 6480464 | Bortezomib results in increased expression of SGPP1 mRNA | CTD | PMID:20977926 | buspirone | increases expression | EXP | | 6480464 | Buspirone results in increased expression of SGPP1 mRNA | CTD | PMID:24136188 | cadmium atom | increases expression | ISO | SGPP1 (Homo sapiens) | 6480464 | Cadmium results in increased expression of SGPP1 mRNA | CTD | PMID:24376830 | cadmium atom | multiple interactions | ISO | Sgpp1 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SGPP1 mRNA | CTD | PMID:37325564 | cadmium atom | multiple interactions | ISO | SGPP1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SGPP1 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | SGPP1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SGPP1 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | Sgpp1 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SGPP1 mRNA | CTD | PMID:37325564 | caffeine | increases phosphorylation | ISO | SGPP1 (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of SGPP1 protein | CTD | PMID:35688186 | carbon nanotube | decreases expression | ISO | Sgpp1 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | cisplatin | decreases expression | ISO | SGPP1 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of SGPP1 mRNA | CTD | PMID:27392435 | clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SGPP1 mRNA | CTD | PMID:17602206 | daidzein | multiple interactions | ISO | SGPP1 (Homo sapiens) | 6480464 | [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of SGPP1 mRNA | CTD | PMID:16963248 | deoxynivalenol | decreases phosphorylation | ISO | Sgpp1 (Mus musculus) | 6480464 | deoxynivalenol results in decreased phosphorylation of SGPP1 protein | CTD | PMID:23811945 | diazinon | affects expression | EXP | | 6480464 | Diazinon affects the expression of SGPP1 mRNA | CTD | PMID:22546817 | dibutyl phthalate | increases expression | ISO | Sgpp1 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of SGPP1 mRNA | CTD | PMID:17361019 and PMID:21266533 | dieldrin | affects expression | EXP | | 6480464 | Dieldrin affects the expression of SGPP1 mRNA | CTD | PMID:22546817 | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of SGPP1 mRNA | CTD | PMID:25152437 | dorsomorphin | multiple interactions | ISO | SGPP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | SGPP1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of SGPP1 mRNA | CTD | PMID:29803840 | fenthion | decreases expression | ISO | Sgpp1 (Mus musculus) | 6480464 | Fenthion results in decreased expression of SGPP1 mRNA | CTD | PMID:34813904 | flutamide | decreases expression | ISO | Sgpp1 (Mus musculus) | 6480464 | Flutamide results in decreased expression of SGPP1 mRNA | CTD | PMID:19442681 | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of SGPP1 mRNA | CTD | PMID:24793618 | folic acid | multiple interactions | ISO | Sgpp1 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of SGPP1 mRNA] | CTD | PMID:22206623 | FR900359 | decreases phosphorylation | ISO | SGPP1 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of SGPP1 protein | CTD | PMID:37730182 | genistein | multiple interactions | ISO | SGPP1 (Homo sapiens) | 6480464 | [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of SGPP1 mRNA | CTD | PMID:16963248 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of SGPP1 mRNA | CTD | PMID:33387578 | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of SGPP1 mRNA | CTD | PMID:24136188 | glycitein | multiple interactions | ISO | SGPP1 (Homo sapiens) | 6480464 | [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of SGPP1 mRNA | CTD | PMID:16963248 | lamivudine | multiple interactions | ISO | Sgpp1 (Mus musculus) | 6480464 | [Zidovudine co-treated with Lamivudine] results in increased expression of SGPP1 mRNA | CTD | PMID:18313992 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of SGPP1 mRNA | CTD | PMID:30467583 | methidathion | decreases expression | ISO | Sgpp1 (Mus musculus) | 6480464 | methidathion results in decreased expression of SGPP1 mRNA | CTD | PMID:34813904 | methylmercury chloride | decreases expression | ISO | SGPP1 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of SGPP1 mRNA | CTD | PMID:23179753 and PMID:28001369 | monosodium L-glutamate | increases expression | ISO | Sgpp1 (Mus musculus) | 6480464 | Sodium Glutamate results in increased expression of SGPP1 mRNA | CTD | PMID:19001666 | N-nitrosodiethylamine | decreases expression | EXP | | 6480464 | Diethylnitrosamine results in decreased expression of SGPP1 mRNA | CTD | PMID:19638242 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SGPP1 mRNA | CTD | PMID:17602206 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of SGPP1 mRNA | CTD | PMID:24136188 | nickel dichloride | affects expression | EXP | | 6480464 | nickel chloride affects the expression of SGPP1 mRNA | CTD | PMID:22546817 | nicotine | decreases expression | ISO | Sgpp1 (Mus musculus) | 6480464 | Nicotine results in decreased expression of SGPP1 mRNA | CTD | PMID:17997037 | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of SGPP1 mRNA | CTD | PMID:24136188 | p-toluidine | decreases expression | EXP | | 6480464 | 4-toluidine results in decreased expression of SGPP1 mRNA | CTD | PMID:27638505 | panobinostat | multiple interactions | ISO | SGPP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SGPP1 mRNA | CTD | PMID:27188386 | panobinostat | increases expression | ISO | SGPP1 (Homo sapiens) | 6480464 | panobinostat results in increased expression of SGPP1 mRNA | CTD | PMID:26272509 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SGPP1 mRNA | CTD | PMID:33387578 | perfluorohexanesulfonic acid | increases expression | ISO | Sgpp1 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in increased expression of SGPP1 mRNA | CTD | PMID:37995155 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Sgpp1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SGPP1 mRNA | CTD | PMID:36331819 | Phenelzine | increases expression | ISO | Sgpp1 (Mus musculus) | 6480464 | Phenelzine results in increased expression of SGPP1 mRNA | CTD | PMID:31249575 | phenobarbital | affects expression | ISO | Sgpp1 (Mus musculus) | 6480464 | Phenobarbital affects the expression of SGPP1 mRNA | CTD | PMID:23091169 | picoxystrobin | increases expression | ISO | SGPP1 (Homo sapiens) | 6480464 | picoxystrobin results in increased expression of SGPP1 mRNA | CTD | PMID:33512557 | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of SGPP1 mRNA | CTD | PMID:28374803 | SB 431542 | multiple interactions | ISO | SGPP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | Sgpp1 (Mus musculus) | 6480464 | Silicon Dioxide results in decreased expression of SGPP1 mRNA | CTD | PMID:19073995 | sodium arsenite | decreases expression | ISO | SGPP1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of SGPP1 mRNA | CTD | PMID:34032870 | sunitinib | increases expression | ISO | SGPP1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of SGPP1 mRNA | CTD | PMID:31533062 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of SGPP1 mRNA | CTD | PMID:34492290 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of SGPP1 mRNA | CTD | PMID:33387578 | trichostatin A | increases expression | ISO | SGPP1 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of SGPP1 mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | ISO | SGPP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SGPP1 mRNA | CTD | PMID:27188386 | urethane | increases expression | ISO | SGPP1 (Homo sapiens) | 6480464 | Urethane results in increased expression of SGPP1 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | Sgpp1 (Mus musculus) | 6480464 | Valproic Acid affects the expression of SGPP1 mRNA | CTD | PMID:17963808 | valproic acid | multiple interactions | ISO | SGPP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SGPP1 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | SGPP1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SGPP1 mRNA | CTD | PMID:24383497 more ... | zidovudine | multiple interactions | ISO | Sgpp1 (Mus musculus) | 6480464 | [Zidovudine co-treated with Lamivudine] results in increased expression of SGPP1 mRNA | CTD | PMID:18313992 | |