Hgfac (HGF activator) - Rat Genome Database

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Gene: Hgfac (HGF activator) Rattus norvegicus
Analyze
Symbol: Hgfac
Name: HGF activator
RGD ID: 70909
Description: Predicted to enable serine-type endopeptidase activity. Predicted to be involved in blood coagulation and zymogen activation. Predicted to be located in cytoplasm. Predicted to be active in extracellular space and rough endoplasmic reticulum. Orthologous to human HGFAC (HGF activator); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hepatocyte growth factor activator; MGC109000
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81479,932,219 - 79,938,773 (-)NCBIGRCr8
mRatBN7.21475,707,588 - 75,714,182 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1475,707,591 - 75,714,278 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1480,160,640 - 80,167,194 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01481,401,267 - 81,407,821 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01477,846,489 - 77,853,043 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01480,966,902 - 80,973,525 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1480,966,903 - 80,973,456 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01481,655,780 - 81,662,442 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41481,348,282 - 81,354,836 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11481,351,701 - 81,351,935 (-)NCBI
Celera1474,633,495 - 74,640,049 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Exogenously Administered HGF Activator Augments Liver Regeneration through the Production of Biologically Active HGF. Kaibori M, etal., Biochem Biophys Res Commun 2002 Jan 11;290(1):475-81.
3. Gene Data Set MGD Curation, June 12, 2002
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Changes in gene expression during progression of ovarian carcinoma. Tapper J, etal., Cancer Genet Cytogenet 2001 Jul 1;128(1):1-6.
Additional References at PubMed
PMID:12477932   PMID:12923239  


Genomics

Comparative Map Data
Hgfac
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81479,932,219 - 79,938,773 (-)NCBIGRCr8
mRatBN7.21475,707,588 - 75,714,182 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1475,707,591 - 75,714,278 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1480,160,640 - 80,167,194 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01481,401,267 - 81,407,821 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01477,846,489 - 77,853,043 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01480,966,902 - 80,973,525 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1480,966,903 - 80,973,456 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01481,655,780 - 81,662,442 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41481,348,282 - 81,354,836 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11481,351,701 - 81,351,935 (-)NCBI
Celera1474,633,495 - 74,640,049 (-)NCBICelera
Cytogenetic Map14q21NCBI
HGFAC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3843,441,005 - 3,449,486 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl43,441,968 - 3,449,486 (+)EnsemblGRCh38hg38GRCh38
GRCh3743,443,695 - 3,451,213 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3643,413,524 - 3,421,011 (+)NCBINCBI36Build 36hg18NCBI36
Build 3443,480,694 - 3,488,182NCBI
Celera43,354,522 - 3,362,009 (+)NCBICelera
Cytogenetic Map4p16.3NCBI
HuRef43,380,866 - 3,388,353 (+)NCBIHuRef
CHM1_143,441,294 - 3,448,781 (+)NCBICHM1_1
T2T-CHM13v2.043,440,789 - 3,449,270 (+)NCBIT2T-CHM13v2.0
Hgfac
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39535,198,853 - 35,205,805 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl535,198,853 - 35,205,805 (+)EnsemblGRCm39 Ensembl
GRCm38535,041,509 - 35,048,461 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl535,041,509 - 35,048,461 (+)EnsemblGRCm38mm10GRCm38
MGSCv37535,384,202 - 35,391,085 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36535,358,455 - 35,365,270 (+)NCBIMGSCv36mm8
Celera532,516,343 - 32,523,227 (+)NCBICelera
Cytogenetic Map5B2NCBI
cM Map517.99NCBI
Hgfac
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555142,155,384 - 2,165,957 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555142,155,924 - 2,161,302 (+)NCBIChiLan1.0ChiLan1.0
HGFAC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v233,785,510 - 3,793,038 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan143,719,251 - 3,726,711 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v043,590,908 - 3,599,781 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.143,575,819 - 3,583,436 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl43,575,819 - 3,583,436 (+)Ensemblpanpan1.1panPan2
HGFAC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1360,906,839 - 60,916,879 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl360,906,844 - 60,915,280 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha363,557,017 - 63,565,265 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0361,382,412 - 61,390,658 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl361,382,412 - 61,390,658 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1360,874,179 - 60,882,422 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0361,080,281 - 61,088,528 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0361,436,631 - 61,444,882 (-)NCBIUU_Cfam_GSD_1.0
Hgfac
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528566,587,535 - 66,597,492 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647720,291,852 - 20,298,764 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647720,291,791 - 20,298,764 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HGFAC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl82,077,176 - 2,084,507 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.182,077,164 - 2,084,506 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.281,757,622 - 1,764,975 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HGFAC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12745,283,213 - 45,290,922 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2745,283,206 - 45,290,644 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660511,638,295 - 1,645,982 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hgfac
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475524,483,431 - 24,488,450 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475524,483,358 - 24,488,505 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hgfac
25 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:56
Count of miRNA genes:52
Interacting mature miRNAs:56
Transcripts:ENSRNOT00000013257
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)145002321195023211Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1455624247100624247Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)146875779683368335Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1470053989104886043Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147341532392554092Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147341532392554092Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532395876975Rat

Markers in Region
MARC_16871-16872:1015445619:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21475,708,664 - 75,709,293 (+)MAPPERmRatBN7.2
Rnor_6.01480,967,979 - 80,968,607NCBIRnor6.0
Rnor_5.01481,656,862 - 81,657,490UniSTSRnor5.0
RGSC_v3.41481,349,359 - 81,349,987UniSTSRGSC3.4
Celera1474,634,572 - 74,635,200UniSTS
Cytogenetic Map14q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 41 41 41 2 4 3
Low 1 8 13 2 2 4 33 30 8 2
Below cutoff 29 8 6 6 6 60 5 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000013257   ⟹   ENSRNOP00000013257
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1475,707,591 - 75,714,278 (-)Ensembl
Rnor_6.0 Ensembl1480,966,903 - 80,973,456 (-)Ensembl
RefSeq Acc Id: NM_053320   ⟹   NP_445772
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81479,932,219 - 79,938,773 (-)NCBI
mRatBN7.21475,707,588 - 75,714,142 (-)NCBI
Rnor_6.01480,966,902 - 80,973,456 (-)NCBI
Rnor_5.01481,655,780 - 81,662,442 (-)NCBI
RGSC_v3.41481,348,282 - 81,354,836 (-)RGD
Celera1474,633,495 - 74,640,049 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_445772 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH89871 (Get FASTA)   NCBI Sequence Viewer  
  BAA25981 (Get FASTA)   NCBI Sequence Viewer  
  EDM00074 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000013257
  ENSRNOP00000013257.5
Reference Protein Sequences
RefSeq Acc Id: NP_445772   ⟸   NM_053320
- Peptide Label: precursor
- UniProtKB: Q5EBA7 (UniProtKB/TrEMBL),   F7ELL4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000013257   ⟸   ENSRNOT00000013257
Protein Domains
EGF-like   Fibronectin type-I   Fibronectin type-II   Kringle   Peptidase S1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5EBA7-F1-model_v2 AlphaFold Q5EBA7 1-653 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699392
Promoter ID:EPDNEW_R9917
Type:initiation region
Name:Hgfac_1
Description:HGF activator
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01480,973,472 - 80,973,532EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70909 AgrOrtholog
BioCyc Gene G2FUF-15312 BioCyc
Ensembl Genes ENSRNOG00000009572 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013257 ENTREZGENE
  ENSRNOT00000013257.7 UniProtKB/TrEMBL
Gene3D-CATH 2.10.10.10 UniProtKB/TrEMBL
  2.40.10.10 UniProtKB/TrEMBL
  2.40.20.10 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7324508 IMAGE-MGC_LOAD
InterPro Coagulation_fac_XIIa/HGFA UniProtKB/TrEMBL
  EG-like_dom UniProtKB/TrEMBL
  Fibronectin_type1 UniProtKB/TrEMBL
  FN_type2_col-bd UniProtKB/TrEMBL
  FN_type2_sf UniProtKB/TrEMBL
  Kringle UniProtKB/TrEMBL
  Kringle-like UniProtKB/TrEMBL
  Kringle_CS UniProtKB/TrEMBL
  Kringle_sf UniProtKB/TrEMBL
  Pept_cys/ser_Trypsin-like UniProtKB/TrEMBL
  Peptidase_S1/S6_AS UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1_S6 UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
KEGG Report rno:58947 UniProtKB/TrEMBL
MGC_CLONE MGC:109000 IMAGE-MGC_LOAD
NCBI Gene 58947 ENTREZGENE
PANTHER HEPATOCYTE GROWTH FACTOR ACTIVATOR UniProtKB/TrEMBL
  TRYPSIN-RELATED UniProtKB/TrEMBL
Pfam EGF UniProtKB/TrEMBL
  fn1 UniProtKB/TrEMBL
  fn2 UniProtKB/TrEMBL
  Kringle UniProtKB/TrEMBL
  Trypsin UniProtKB/TrEMBL
PhenoGen Hgfac PhenoGen
PIRSF Factor_XII_HGFA UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
  FNTYPEII UniProtKB/TrEMBL
  KRINGLE UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  FN1_1 UniProtKB/TrEMBL
  FN1_2 UniProtKB/TrEMBL
  FN2_1 UniProtKB/TrEMBL
  FN2_2 UniProtKB/TrEMBL
  KRINGLE_1 UniProtKB/TrEMBL
  KRINGLE_2 UniProtKB/TrEMBL
  TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009572 RatGTEx
SMART EGF UniProtKB/TrEMBL
  FN1 UniProtKB/TrEMBL
  FN2 UniProtKB/TrEMBL
  SM00130 UniProtKB/TrEMBL
  Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  FnI-like domain UniProtKB/TrEMBL
  Kringle-like UniProtKB/TrEMBL
  Pept_Ser_Cys UniProtKB/TrEMBL
UniProt F7ELL4 ENTREZGENE, UniProtKB/TrEMBL
  Q5EBA7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-15 Hgfac  HGF activator  Hgfac  hepatocyte growth factor activator  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-07-09 Hgfac  hepatocyte growth factor activator      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_function cleaves hepatocyte growth factor precursor (pro Hgf) to form mature Hgf 70251