Erap1 (endoplasmic reticulum aminopeptidase 1) - Rat Genome Database

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Gene: Erap1 (endoplasmic reticulum aminopeptidase 1) Rattus norvegicus
Analyze
Symbol: Erap1
Name: endoplasmic reticulum aminopeptidase 1
RGD ID: 708542
Description: Enables aminopeptidase activity; tumor necrosis factor receptor binding activity; and zinc ion binding activity. Involved in protein catabolic process. Located in endoplasmic reticulum lumen. Human ortholog(s) of this gene implicated in cervix carcinoma. Orthologous to human ERAP1 (endoplasmic reticulum aminopeptidase 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A-LAP; adipocyte-derived leucine aminopeptidase; aminopeptidase PILS; Appils; ARTS-1; Arts1; ER-aminopeptidase 1; leucyl-specific aminopeptidase PILS; MGC112613; PILS-AP; puromycin-insensitive leucyl-specific aminopeptidase; type 1 tumor necrosis factor receptor shedding aminopeptidase regulator
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr825,666,337 - 5,705,256 (+)NCBIGRCr8
mRatBN7.223,931,817 - 3,970,735 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl23,931,904 - 3,972,447 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx211,040,964 - 11,079,787 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.029,140,189 - 9,179,011 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.023,777,162 - 3,815,982 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.021,410,877 - 1,449,734 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl21,410,934 - 1,449,733 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.021,381,061 - 1,419,645 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.421,453,878 - 1,492,671 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.121,457,924 - 1,492,670 (+)NCBI
Celera2431,649 - 466,037 (+)NCBICelera
Cytogenetic Map2q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Single nucleotide polymorphisms in antigen processing machinery component ERAP1 significantly associate with clinical outcome in cervical carcinoma. Mehta AM, etal., Genes Chromosomes Cancer. 2009 May;48(5):410-8.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. 14-Deoxyandrographolide desensitizes hepatocytes to tumour necrosis factor-alpha-induced apoptosis through calcium-dependent tumour necrosis factor receptor superfamily member 1A release via the NO/cGMP pathway. Roy DN, etal., Br J Pharmacol. 2010 Aug;160(7):1823-43.
7. An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides. Saric T, etal., Nat Immunol 2002 Dec;3(12):1169-76.
8. Molecular characterization of a puromycin-insensitive leucyl-specific aminopeptidase, PILS-AP. Schomburg L, etal., Eur J Biochem 2000 Jun;267(11):3198-207.
9. All the peptides that fit: the beginning, the middle, and the end of the MHC class I antigen-processing pathway. Shastri N, etal., Immunol Rev. 2005 Oct;207:31-41.
10. Possible involvement of adipocyte-derived leucine aminopeptidase via angiotensin II in endometrial carcinoma. Shibata K, etal., Tumour Biol. 2005 Jan-Feb;26(1):9-16. Epub 2005 Feb 28.
11. Increased decidual mRNA expression levels of candidate maternal pre-eclampsia susceptibility genes are associated with clinical severity. Yong HE, etal., Placenta. 2014 Feb;35(2):117-24. doi: 10.1016/j.placenta.2013.11.008. Epub 2013 Nov 25.
Additional References at PubMed
PMID:10220586   PMID:11056387   PMID:11964289   PMID:12436110   PMID:12477932   PMID:12748171   PMID:16502470   PMID:17088086   PMID:19199708   PMID:19946888   PMID:23610143  


Genomics

Comparative Map Data
Erap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr825,666,337 - 5,705,256 (+)NCBIGRCr8
mRatBN7.223,931,817 - 3,970,735 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl23,931,904 - 3,972,447 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx211,040,964 - 11,079,787 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.029,140,189 - 9,179,011 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.023,777,162 - 3,815,982 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.021,410,877 - 1,449,734 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl21,410,934 - 1,449,733 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.021,381,061 - 1,419,645 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.421,453,878 - 1,492,671 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.121,457,924 - 1,492,670 (+)NCBI
Celera2431,649 - 466,037 (+)NCBICelera
Cytogenetic Map2q11NCBI
ERAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38596,760,813 - 96,935,854 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl596,760,810 - 96,808,100 (-)EnsemblGRCh38hg38GRCh38
GRCh37596,096,517 - 96,149,848 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36596,122,270 - 96,169,648 (-)NCBINCBI36Build 36hg18NCBI36
Build 34596,122,276 - 96,169,398NCBI
Celera591,980,937 - 92,028,293 (-)NCBICelera
Cytogenetic Map5q15NCBI
HuRef591,286,769 - 91,340,086 (-)NCBIHuRef
CHM1_1595,529,237 - 95,582,553 (-)NCBICHM1_1
T2T-CHM13v2.0597,261,648 - 97,314,923 (-)NCBIT2T-CHM13v2.0
Erap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391374,787,692 - 74,841,321 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1374,787,687 - 74,841,320 (+)EnsemblGRCm39 Ensembl
GRCm381374,639,573 - 74,693,205 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1374,639,568 - 74,693,201 (+)EnsemblGRCm38mm10GRCm38
MGSCv371374,777,320 - 74,829,323 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361375,105,874 - 75,157,877 (+)NCBIMGSCv36mm8
Celera1376,970,386 - 77,021,970 (+)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1340.48NCBI
Erap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541815,830,371 - 15,859,720 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541815,827,560 - 15,859,720 (+)NCBIChiLan1.0ChiLan1.0
ERAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2492,022,595 - 92,056,016 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1590,176,243 - 90,337,794 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0592,061,414 - 92,119,087 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1597,625,811 - 97,799,499 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl597,641,353 - 97,668,365 (-)Ensemblpanpan1.1panPan2
ERAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1312,879,823 - 12,920,710 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl312,879,477 - 12,919,634 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha314,217,433 - 14,261,168 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0312,760,873 - 12,803,107 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl312,760,934 - 12,803,102 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1312,721,683 - 12,764,349 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0312,716,755 - 12,760,524 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0312,916,519 - 12,958,941 (+)NCBIUU_Cfam_GSD_1.0
Erap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213168,475,893 - 168,502,935 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365236,661,315 - 6,690,425 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365236,661,119 - 6,686,988 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ERAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2103,378,429 - 103,408,759 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12103,378,428 - 103,415,066 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22107,137,501 - 107,167,876 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ERAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1490,591,198 - 90,642,331 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl490,600,690 - 90,637,563 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604939,248,974 - 39,415,702 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Erap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474315,408,485 - 15,431,967 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474315,407,217 - 15,442,610 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Erap1
38 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:47
Count of miRNA genes:45
Interacting mature miRNAs:46
Transcripts:ENSRNOT00000013625
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631682Bp115Blood pressure QTL 1154.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2137410502Rat
738010Lnnr3Liver neoplastic nodule remodeling QTL 32.94liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)2141244106Rat

Markers in Region
UniSTS:495933  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.223,942,869 - 3,942,964 (+)MAPPERmRatBN7.2
Rnor_6.021,421,869 - 1,421,963NCBIRnor6.0
Rnor_5.021,392,045 - 1,392,139UniSTSRnor5.0
RGSC_v3.421,464,806 - 1,464,900UniSTSRGSC3.4
Celera2438,530 - 438,624UniSTS
Cytogenetic Map2q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 32 57 41 19 41 8 8 23 34 33 11 8
Low 11 3 51 1 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001399166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006231700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006231701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC111648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF148323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF148324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC080238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC098664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000013625   ⟹   ENSRNOP00000013625
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl23,931,921 - 3,970,734 (+)Ensembl
Rnor_6.0 Ensembl21,410,934 - 1,449,733 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000080222   ⟹   ENSRNOP00000072424
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl23,931,942 - 3,970,734 (+)Ensembl
Rnor_6.0 Ensembl21,410,941 - 1,449,733 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000103131   ⟹   ENSRNOP00000084733
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl23,931,904 - 3,972,447 (+)Ensembl
RefSeq Acc Id: NM_001399166   ⟹   NP_001386095
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr825,666,436 - 5,705,256 (+)NCBI
mRatBN7.223,931,915 - 3,970,735 (+)NCBI
RefSeq Acc Id: XM_006231700   ⟹   XP_006231762
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr825,666,460 - 5,705,256 (+)NCBI
mRatBN7.223,931,925 - 3,970,735 (+)NCBI
Rnor_6.021,410,938 - 1,449,734 (+)NCBI
Rnor_5.021,381,061 - 1,419,645 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006231701   ⟹   XP_006231763
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr825,666,338 - 5,705,256 (+)NCBI
mRatBN7.223,931,818 - 3,970,735 (+)NCBI
Rnor_6.021,410,877 - 1,449,734 (+)NCBI
Rnor_5.021,381,061 - 1,419,645 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008760601   ⟹   XP_008758823
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr825,666,337 - 5,705,256 (+)NCBI
mRatBN7.223,931,817 - 3,970,735 (+)NCBI
Rnor_6.021,412,827 - 1,449,734 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063282612   ⟹   XP_063138682
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr825,666,441 - 5,705,256 (+)NCBI
RefSeq Acc Id: XM_063282613   ⟹   XP_063138683
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr825,666,338 - 5,705,256 (+)NCBI
RefSeq Acc Id: XM_063282614   ⟹   XP_063138684
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr825,690,292 - 5,705,256 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_006231763   ⟸   XM_006231701
- Peptide Label: isoform X1
- UniProtKB: Q9JJ23 (UniProtKB/Swiss-Prot),   Q9JJ22 (UniProtKB/Swiss-Prot),   F7F4R3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231762   ⟸   XM_006231700
- Peptide Label: isoform X1
- UniProtKB: Q9JJ23 (UniProtKB/Swiss-Prot),   Q9JJ22 (UniProtKB/Swiss-Prot),   F7F4R3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008758823   ⟸   XM_008760601
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K2Y3 (UniProtKB/TrEMBL),   A6I4D9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000072424   ⟸   ENSRNOT00000080222
RefSeq Acc Id: ENSRNOP00000013625   ⟸   ENSRNOT00000013625
RefSeq Acc Id: ENSRNOP00000084733   ⟸   ENSRNOT00000103131
RefSeq Acc Id: NP_001386095   ⟸   NM_001399166
- Peptide Label: precursor
- UniProtKB: Q4KMA8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138683   ⟸   XM_063282613
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZYK5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138682   ⟸   XM_063282612
- Peptide Label: isoform X3
- UniProtKB: Q4KMA8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138684   ⟸   XM_063282614
- Peptide Label: isoform X5
Protein Domains
Aminopeptidase N-like N-terminal   ERAP1-like C-terminal   Peptidase M1 membrane alanine aminopeptidase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JJ22-F1-model_v2 AlphaFold Q9JJ22 1-930 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691029
Promoter ID:EPDNEW_R1554
Type:multiple initiation site
Name:Erap1_1
Description:endoplasmic reticulum aminopeptidase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.021,410,914 - 1,410,974EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708542 AgrOrtholog
BioCyc Gene G2FUF-55117 BioCyc
Ensembl Genes ENSRNOG00000009997 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013625.6 UniProtKB/TrEMBL
  ENSRNOT00000080222.2 UniProtKB/TrEMBL
  ENSRNOT00000103131 ENTREZGENE
  ENSRNOT00000103131.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.390.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.25.50.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.1730 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.1910 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7192921 IMAGE-MGC_LOAD
InterPro Aminopeptidase_N-like_N UniProtKB/Swiss-Prot
  Aminopeptidase_N-like_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Aminopeptidase_N-like_N UniProtKB/TrEMBL
  ERAP1-like_C_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  M1_APN-typ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M1_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M4/M1_CTD_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:80897 UniProtKB/Swiss-Prot
MGC_CLONE MGC:112613 IMAGE-MGC_LOAD
NCBI Gene 80897 ENTREZGENE
PANTHER PROTEASE M1 ZINC METALLOPROTEASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11533:SF156 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ERAP1_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M1_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Erap1 PhenoGen
PRINTS ALADIPTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ZINC_PROTEASE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000009997 RatGTEx
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF63737 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K2Y3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZYK5 ENTREZGENE, UniProtKB/TrEMBL
  A6I4D9 ENTREZGENE, UniProtKB/TrEMBL
  ERAP1_RAT UniProtKB/Swiss-Prot
  F7F4R3 ENTREZGENE, UniProtKB/TrEMBL
  Q4KMA8 ENTREZGENE, UniProtKB/TrEMBL
  Q9JJ22 ENTREZGENE
  Q9JJ23 ENTREZGENE
UniProt Secondary Q9JJ23 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-25 Erap1  endoplasmic reticulum aminopeptidase 1  Arts1  type 1 tumor necrosis factor receptor shedding aminopeptidase regulator  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Arts1  type 1 tumor necrosis factor receptor shedding aminopeptidase regulator  Appils  leucyl-specific aminopeptidase PILS  Symbol and Name updated 1299863 APPROVED