(+)-catechin multiple interactions EXP 6480464 Catechin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:23365609 (-)-cotinine multiple interactions EXP 6480464 [Nicotine results in increased abundance of Cotinine] which results in increased expression of SREBF1 mRNA CTD PMID:29617909 (-)-demecolcine decreases expression ISO RGD:69473 6480464 Demecolcine results in decreased expression of SREBF1 mRNA CTD PMID:23649840 (-)-epigallocatechin 3-gallate decreases expression ISO RGD:69473 6480464 epigallocatechin gallate results in decreased expression of SREBF1 mRNA CTD PMID:20816778 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:69474 6480464 epigallocatechin gallate inhibits the reaction [1 more ... CTD PMID:30092300 (2,4,5-trichlorophenoxy)acetic acid increases expression ISO RGD:69474 6480464 2 more ... CTD PMID:18579281 (25R)-cholest-5-ene-3beta,26-diol decreases expression EXP 6480464 27-hydroxycholesterol results in decreased expression of SREBF1 mRNA, 27-hydroxycholesterol results in decreased expression of SREBF1 protein CTD PMID:28167099 (R)-carnitine multiple interactions EXP 6480464 Carnitine inhibits the reaction [Stavudine results in increased expression of SREBF1 mRNA] CTD PMID:18299183 (R)-lipoic acid multiple interactions EXP 6480464 Thioctic Acid inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:22464149 (S)-nicotine decreases expression ISO RGD:69473 6480464 Nicotine results in decreased expression of SREBF1 mRNA CTD PMID:18247414 (S)-nicotine increases expression ISO RGD:69474 6480464 Nicotine results in increased expression of SREBF1 mRNA CTD PMID:31622651 (S)-nicotine multiple interactions EXP 6480464 [Nicotine results in increased abundance of Cotinine] which results in increased expression of SREBF1 mRNA CTD PMID:29617909 (S)-nicotine increases expression EXP 6480464 Nicotine results in increased expression of SREBF1 mRNA CTD PMID:29155039 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression ISO RGD:69474 6480464 o, p'-DDT affects the expression of SREBF1 mRNA CTD PMID:18925944 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression EXP 6480464 o, p'-DDT affects the expression of SREBF1 mRNA CTD PMID:17984292 1,10-phenanthroline multiple interactions ISO RGD:69473 6480464 [1 more ... CTD PMID:21355074 1,3-dichloropropan-2-ol increases expression ISO RGD:69474 6480464 1 more ... CTD PMID:24333398 , PMID:30092300 1,3-dichloropropan-2-ol multiple interactions ISO RGD:69474 6480464 epigallocatechin gallate inhibits the reaction [1 more ... CTD PMID:30092300 1,3-dichloropropan-2-ol multiple interactions ISO RGD:69473 6480464 alliin inhibits the reaction [1 more ... CTD PMID:29305303 1,3-dichloropropan-2-ol increases expression ISO RGD:69473 6480464 1 more ... CTD PMID:29305303 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile multiple interactions ISO RGD:69473 6480464 Citalopram results in increased cleavage of and results in increased activity of SREBF1 protein CTD PMID:16324787 1-benzylpiperazine increases expression EXP 6480464 N-benzylpiperazine results in increased expression of SREBF1 mRNA CTD PMID:26821219 1-naphthyl isothiocyanate decreases expression EXP 6480464 1-Naphthylisothiocyanate results in decreased expression of SREBF1 mRNA CTD PMID:17522070 , PMID:25380136 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of SREBF1 mRNA CTD PMID:30723492 14-Deoxy-11,12-didehydroandrographolide multiple interactions ISO RGD:69474 6480464 14-deoxy-11 more ... CTD PMID:30248417 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of SREBF1 mRNA CTD PMID:17108234 17alpha-ethynylestradiol multiple interactions ISO RGD:69474 6480464 [lard co-treated with Cholesterol co-treated with Sucrose co-treated with Ethinyl Estradiol] results in increased expression of SREBF1 mRNA CTD PMID:24440342 17beta-estradiol multiple interactions ISO RGD:69473 6480464 [Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:21768169 , PMID:31730885 17beta-estradiol decreases expression ISO RGD:69473 6480464 Estradiol results in decreased expression of SREBF1 mRNA CTD PMID:31614463 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of SREBF1 mRNA, Estradiol results in decreased expression of SREBF1 protein CTD PMID:26164745 17beta-estradiol multiple interactions ISO RGD:69474 6480464 1 more ... CTD PMID:21768169 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:69473 6480464 Dihydrotestosterone results in increased expression of SREBF1 mRNA CTD PMID:16541421 2,2',4,4',5,5'-hexachlorobiphenyl decreases expression ISO RGD:69474 6480464 2 more ... CTD PMID:20005886 , PMID:21851831 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:69474 6480464 2 more ... CTD PMID:21851831 more ... 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO RGD:69473 6480464 2 more ... CTD PMID:19095052 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:69474 6480464 Tetrachlorodibenzodioxin affects the expression of SREBF1 mRNA CTD PMID:24058054 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of SREBF1 mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of SREBF1 mRNA CTD PMID:21215274 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:69474 6480464 Tetrachlorodibenzodioxin results in increased expression of SREBF1 mRNA CTD PMID:21846477 , PMID:25975270 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:69474 6480464 Tetrachlorodibenzodioxin results in decreased expression of SREBF1 mRNA, Tetrachlorodibenzodioxin results in decreased expression of SREBF1 protein CTD PMID:18295293 more ... 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:69474 6480464 2 more ... CTD PMID:16054899 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:69473 6480464 Tetrachlorodibenzodioxin results in decreased expression of SREBF1 mRNA CTD PMID:20106945 2,3,7,8-Tetrachlorodibenzofuran increases expression ISO RGD:69474 6480464 2 more ... CTD PMID:34097992 2,3,7,8-Tetrachlorodibenzofuran multiple interactions ISO RGD:69474 6480464 AHR gene mutant form inhibits the reaction [2 more ... CTD PMID:34097992 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of SREBF1 mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of SREBF1 mRNA CTD PMID:21346803 2-amino-2-deoxy-D-glucopyranose 6-phosphate decreases expression ISO RGD:69474 6480464 glucosamine 6-phosphate results in decreased expression of SREBF1 protein CTD PMID:19427183 2-deoxy-D-glucose increases expression ISO RGD:69474 6480464 Deoxyglucose results in increased expression of SREBF1 mRNA CTD PMID:10913129 2-naphthylamine decreases expression ISO RGD:69473 6480464 2-Naphthylamine results in decreased expression of SREBF1 mRNA CTD PMID:18247414 22-Hydroxycholesterol increases expression ISO RGD:69474 6480464 22-hydroxycholesterol results in increased expression of SREBF1 mRNA, 22-hydroxycholesterol results in increased expression of SREBF1 protein CTD PMID:16763553 22-Hydroxycholesterol multiple interactions ISO RGD:69473 6480464 [22-hydroxycholesterol co-treated with Alitretinoin] inhibits the reaction [Arsenic Trioxide results in decreased expression of SREBF1 protein] CTD PMID:27622732 22-Hydroxycholesterol multiple interactions ISO RGD:69474 6480464 22-hydroxycholesterol promotes the reaction [SREBF1 protein binds to ALDH1A1 promoter], 22-hydroxycholesterol promotes the reaction [SREBF1 protein binds to ALDH1A2 promoter] CTD PMID:16763553 25-hydroxycholesterol increases expression ISO RGD:69474 6480464 25-hydroxycholesterol results in increased expression of SREBF1 protein CTD PMID:19260826 25-hydroxycholesterol multiple interactions ISO RGD:69473 6480464 [25-hydroxycholesterol co-treated with Cholesterol] results in decreased cleavage of SREBF1 protein CTD PMID:27324795 26-hydroxycholesterol decreases expression EXP 6480464 27-hydroxycholesterol results in decreased expression of SREBF1 mRNA, 27-hydroxycholesterol results in decreased expression of SREBF1 protein CTD PMID:28167099 28-Homobrassinolide increases expression EXP 6480464 homobrassinolide results in increased expression of SREBF1 mRNA CTD PMID:21491949 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO RGD:69474 6480464 3 more ... CTD PMID:23994337 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:26693162 3,3',5,5'-tetrabromobisphenol A increases expression ISO RGD:69474 6480464 tetrabromobisphenol A results in increased expression of SREBF1 mRNA CTD PMID:30496566 3,3',5-triiodo-L-thyronine multiple interactions EXP 6480464 SIRT1 protein affects the reaction [Triiodothyronine results in decreased activity of SREBF1 protein], SIRT1 protein affects the reaction [Triiodothyronine results in decreased expression of SREBF1 mRNA] CTD PMID:23209300 3,3',5-triiodo-L-thyronine multiple interactions ISO RGD:69473 6480464 [Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of SREBF1 mRNA, rosemarinic acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of SREBF1 mRNA] CTD PMID:33476690 3,3',5-triiodo-L-thyronine decreases expression EXP 6480464 Triiodothyronine results in decreased expression of SREBF1 mRNA CTD PMID:23209300 3,3',5-triiodo-L-thyronine decreases activity EXP 6480464 Triiodothyronine results in decreased activity of SREBF1 protein CTD PMID:23209300 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:69474 6480464 14-deoxy-11 more ... CTD PMID:11101056 more ... 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:69473 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA more ... CTD PMID:26200599 more ... 3-phenylprop-2-enal decreases expression ISO RGD:69474 6480464 cinnamaldehyde results in decreased expression of SREBF1 mRNA CTD PMID:21401097 3-phenylprop-2-enal multiple interactions ISO RGD:69474 6480464 dorsomorphin inhibits the reaction [cinnamaldehyde results in decreased expression of SREBF1 mRNA] CTD PMID:21401097 3H-1,2-dithiole-3-thione increases expression EXP 6480464 1, 2-dithiol-3-thione results in increased expression of SREBF1 mRNA CTD PMID:19162173 4,4'-diaminodiphenylmethane decreases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of SREBF1 mRNA CTD PMID:25380136 4,4'-diaminodiphenylmethane decreases expression ISO RGD:69474 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of SREBF1 mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol increases expression ISO RGD:69473 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of SREBF1 mRNA CTD PMID:27003841 4,4'-sulfonyldiphenol affects methylation ISO RGD:69474 6480464 bis(4-hydroxyphenyl)sulfone affects the methylation of SREBF1 exon CTD PMID:33297965 4,4'-sulfonyldiphenol increases expression ISO RGD:69474 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of SREBF1 mRNA CTD PMID:30145421 4-nonylphenol increases expression EXP 6480464 4-nonylphenol results in increased expression of SREBF1 mRNA CTD PMID:24388992 4-phenylbutyric acid multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [AGT protein results in increased cleavage of SREBF1 protein], 4-phenylbutyric acid inhibits the reaction [AGT protein results in increased expression of SREBF1 mRNA] CTD PMID:25398788 4-tert-Octylphenol decreases expression EXP 6480464 4-tert-octylphenol results in decreased expression of SREBF1 mRNA, 4-tert-octylphenol results in decreased expression of SREBF1 protein CTD PMID:26164745 5-aza-2'-deoxycytidine multiple interactions ISO RGD:69473 6480464 [Decitabine co-treated with Depsipeptides] results in increased expression of SREBF1 mRNA CTD PMID:17064661 5-fluorouracil affects expression ISO RGD:69473 6480464 Fluorouracil affects the expression of SREBF1 mRNA CTD PMID:34151400 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime decreases expression ISO RGD:69473 6480464 6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:21768169 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime increases expression ISO RGD:69473 6480464 6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:27180240 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime multiple interactions ISO RGD:69473 6480464 [6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:21768169 , PMID:30611723 8'-apo-beta,psi-caroten-8'-al increases expression ISO RGD:69473 6480464 apocarotenal results in increased expression of SREBF1 mRNA CTD PMID:17034753 8-Br-cAMP decreases expression ISO RGD:69473 6480464 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of SREBF1 mRNA CTD PMID:22079614 9-cis,11-trans-octadecadienoic acid affects expression ISO RGD:69474 6480464 cis-9, trans-11-conjugated linoleic acid affects the expression of SREBF1 mRNA CTD PMID:17327424 9-cis-retinoic acid multiple interactions ISO RGD:69473 6480464 [22-hydroxycholesterol co-treated with Alitretinoin] inhibits the reaction [Arsenic Trioxide results in decreased expression of SREBF1 protein] CTD PMID:27622732 acadesine multiple interactions ISO RGD:69473 6480464 acadesine inhibits the reaction [Dibutyl Phthalate results in increased expression of SREBF1 protein] CTD PMID:33508418 acetaldehyde increases expression EXP 6480464 Acetaldehyde results in increased expression of SREBF1 protein CTD PMID:12036955 acetaldehyde increases expression ISO RGD:69473 6480464 Acetaldehyde results in increased expression of SREBF1 protein CTD PMID:12612910 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of SREBF1 mRNA CTD PMID:31881176 acetylleucyl-leucyl-norleucinal multiple interactions ISO RGD:69473 6480464 acetylleucyl-leucyl-norleucinal inhibits the reaction [SGA 360 results in increased degradation of and results in decreased expression of SREBF1 protein] CTD PMID:31225620 acrolein multiple interactions ISO RGD:69473 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of SREBF1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of SREBF1 mRNA CTD PMID:32699268 acrylamide multiple interactions ISO RGD:69474 6480464 Acrylamide inhibits the reaction [Streptozocin results in increased expression of SREBF1 mRNA] more ... CTD PMID:30409764 , PMID:34896238 acrylamide decreases expression ISO RGD:69474 6480464 Acrylamide results in decreased expression of SREBF1 mRNA CTD PMID:34896238 aflatoxin B1 affects expression ISO RGD:69473 6480464 Aflatoxin B1 affects the expression of SREBF1 protein CTD PMID:20106945 aflatoxin B1 decreases expression ISO RGD:69473 6480464 Aflatoxin B1 results in decreased expression of SREBF1 mRNA CTD PMID:21641981 , PMID:27153756 aflatoxin B1 multiple interactions EXP 6480464 [sulforaphane co-treated with Aflatoxin B1] affects the expression of SREBF1 mRNA CTD PMID:25450479 alcohol multiple interactions ISO RGD:69474 6480464 Apigenin inhibits the reaction [Alcohols results in increased expression of SREBF1 protein], Glutathione inhibits the reaction [Alcohols results in increased expression of SREBF1 protein] CTD PMID:28803762 alcohol increases expression ISO RGD:69474 6480464 Alcohols results in increased expression of SREBF1 protein CTD PMID:28803762 aldehydo-D-glucosamine 6-phosphate decreases expression ISO RGD:69474 6480464 glucosamine 6-phosphate results in decreased expression of SREBF1 protein CTD PMID:19427183 aldehydo-D-glucose increases expression ISO RGD:69473 6480464 Glucose results in increased expression of SREBF1 mRNA, Glucose results in increased expression of SREBF1 protein CTD PMID:23319015 , PMID:23647015 aldehydo-D-glucose multiple interactions ISO RGD:69474 6480464 resveratrol inhibits the reaction [Glucose results in increased expression of SREBF1 protein] CTD PMID:23090186 aldehydo-D-glucose increases expression ISO RGD:69474 6480464 Glucose results in increased expression of SREBF1 mRNA, Glucose results in increased expression of SREBF1 protein CTD PMID:10913129 more ... aldehydo-D-glucose multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased cleavage of SREBF1 protein] more ... CTD PMID:22031849 , PMID:23647015 aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of SREBF1 protein CTD PMID:23647015 aldehydo-D-glucose multiple interactions ISO RGD:69473 6480464 [INS protein co-treated with Glucose] results in increased expression of SREBF1 mRNA more ... CTD PMID:19724016 more ... aldrin increases expression ISO RGD:69474 6480464 Aldrin results in increased expression of SREBF1 mRNA CTD PMID:18579281 all-trans-retinoic acid multiple interactions ISO RGD:69474 6480464 AGN 193109 inhibits the reaction [Tretinoin results in increased expression of SREBF1 mRNA] CTD PMID:16505366 all-trans-retinoic acid increases expression ISO RGD:69473 6480464 Tretinoin results in increased expression of SREBF1 mRNA CTD PMID:33167477 all-trans-retinoic acid increases expression ISO RGD:69474 6480464 Tretinoin results in increased expression of SREBF1 mRNA CTD PMID:16505366 alliin multiple interactions ISO RGD:69473 6480464 alliin inhibits the reaction [1 more ... CTD PMID:29305303 allopurinol multiple interactions EXP 6480464 Allopurinol inhibits the reaction [Glucose results in increased expression of SREBF1 protein] more ... CTD PMID:23647015 allopurinol multiple interactions ISO RGD:69473 6480464 Allopurinol inhibits the reaction [Glucose results in increased expression of SREBF1 protein] CTD PMID:23647015 alpha-D-galactose increases expression ISO RGD:69474 6480464 Galactose results in increased expression of SREBF1 mRNA CTD PMID:10913129 alpha-linolenic acid decreases expression EXP 6480464 alpha-Linolenic Acid results in decreased expression of SREBF1 mRNA CTD PMID:14563831 alpha-pinene multiple interactions ISO RGD:69473 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of SREBF1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of SREBF1 mRNA CTD PMID:32699268 amentoflavone decreases expression ISO RGD:69473 6480464 amentoflavone results in decreased expression of SREBF1 mRNA CTD PMID:34599948 amiodarone decreases expression EXP 6480464 Amiodarone results in decreased expression of SREBF1 mRNA CTD PMID:17202758 amiodarone increases expression ISO RGD:69473 6480464 Amiodarone results in increased expression of SREBF1 mRNA CTD PMID:32651653 amiodarone decreases expression ISO RGD:69474 6480464 Amiodarone results in decreased expression of SREBF1 mRNA CTD PMID:28962527 amitriptyline multiple interactions ISO RGD:69473 6480464 Amitriptyline results in increased cleavage of and results in increased activity of SREBF1 protein CTD PMID:16324787 amlexanox decreases expression ISO RGD:69474 6480464 amlexanox results in decreased expression of SREBF1 mRNA CTD PMID:32905826 amlexanox multiple interactions ISO RGD:69474 6480464 amlexanox inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 mRNA] CTD PMID:32905826 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of SREBF1 mRNA CTD PMID:16483693 amphotericin B multiple interactions ISO RGD:69474 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA], [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA CTD PMID:36464106 ampicillin multiple interactions ISO RGD:69474 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA], [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA CTD PMID:36464106 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:69473 6480464 pyrazolanthrone inhibits the reaction [FGF7 protein results in increased expression of SREBF1 protein] CTD PMID:16162944 apigenin multiple interactions ISO RGD:69474 6480464 Apigenin inhibits the reaction [Alcohols results in increased expression of SREBF1 protein] CTD PMID:28803762 aristolochic acid A decreases expression ISO RGD:69473 6480464 aristolochic acid I results in decreased expression of SREBF1 mRNA CTD PMID:33212167 arsane multiple interactions ISO RGD:69474 6480464 [APOE protein affects the susceptibility to Arsenic] which results in increased expression of SREBF1 protein CTD PMID:22719926 arsenic atom multiple interactions ISO RGD:69474 6480464 [APOE protein affects the susceptibility to Arsenic] which results in increased expression of SREBF1 protein CTD PMID:22719926 arsenous acid decreases expression ISO RGD:69473 6480464 Arsenic Trioxide results in decreased expression of SREBF1 mRNA, Arsenic Trioxide results in decreased expression of SREBF1 protein CTD PMID:20339114 more ... arsenous acid multiple interactions ISO RGD:69473 6480464 [22-hydroxycholesterol co-treated with Alitretinoin] inhibits the reaction [Arsenic Trioxide results in decreased expression of SREBF1 protein] CTD PMID:27622732 arsenous acid decreases expression ISO RGD:69474 6480464 Arsenic Trioxide results in decreased expression of SREBF1 mRNA, Arsenic Trioxide results in decreased expression of SREBF1 protein CTD PMID:20339114 , PMID:30237538 atazanavir sulfate multiple interactions ISO RGD:69473 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of SREBF1 mRNA CTD PMID:33819548 atorvastatin calcium multiple interactions EXP 6480464 [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of SREBF1 protein], Atorvastatin inhibits the reaction [Fructose results in increased activity of SREBF1 protein] CTD PMID:19053045 , PMID:32259528 atrazine multiple interactions ISO RGD:69474 6480464 [lard co-treated with Cholesterol co-treated with Sucrose co-treated with Atrazine] results in increased expression of SREBF1 mRNA CTD PMID:24440342 Azaspiracid increases expression ISO RGD:69473 6480464 azaspiracid results in increased expression of SREBF1 mRNA CTD PMID:28939011 AZD4547 decreases expression ISO RGD:69473 6480464 AZD4547 results in decreased expression of SREBF1 protein CTD PMID:26853465 azoxystrobin multiple interactions ISO RGD:69474 6480464 [azoxystrobin co-treated with Dietary Fats] affects the expression of SREBF1 mRNA CTD PMID:24726979 baicalein decreases expression ISO RGD:69474 6480464 baicalein results in decreased expression of SREBF1 protein CTD PMID:24560969 benzene affects expression EXP 6480464 Benzene affects the expression of SREBF1 mRNA CTD PMID:15878777 benzene increases expression ISO RGD:69473 6480464 Benzene results in increased expression of SREBF1 mRNA CTD PMID:19162166 benzo[a]pyrene increases mutagenesis ISO RGD:69473 6480464 Benzo(a)pyrene results in increased mutagenesis of SREBF1 gene CTD PMID:25435355 benzo[a]pyrene decreases methylation ISO RGD:69473 6480464 Benzo(a)pyrene results in decreased methylation of SREBF1 3' UTR CTD PMID:27901495 benzo[a]pyrene multiple interactions ISO RGD:69473 6480464 Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 mRNA]], Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 protein]] CTD PMID:31730885 benzo[a]pyrene affects methylation ISO RGD:69473 6480464 Benzo(a)pyrene affects the methylation of SREBF1 promoter CTD PMID:27901495 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of SREBF1 mRNA CTD PMID:26303333 benzo[a]pyrene decreases expression ISO RGD:69473 6480464 Benzo(a)pyrene results in decreased expression of SREBF1 mRNA CTD PMID:18247414 more ... benzo[a]pyrene multiple interactions ISO RGD:69474 6480464 Benzo(a)pyrene affects the reaction [GCLM gene mutant form results in decreased expression of SREBF1 mRNA] more ... CTD PMID:24291350 , PMID:31730885 benzylpenicillin multiple interactions ISO RGD:69474 6480464 [Penicillin G co-treated with Erythromycin] results in increased expression of SREBF1 mRNA CTD PMID:27503388 berberine multiple interactions ISO RGD:69474 6480464 Berberine inhibits the reaction [Clozapine results in increased expression of SREBF1 mRNA] more ... CTD PMID:20564506 berberine decreases expression ISO RGD:69473 6480464 Berberine results in decreased expression of SREBF1 mRNA CTD PMID:26478571 beta-carotene increases expression ISO RGD:69473 6480464 beta Carotene results in increased expression of SREBF1 mRNA CTD PMID:17034753 beta-D-glucosamine 6-sulfate decreases expression ISO RGD:69474 6480464 glucosamine 6-O-sulfate results in decreased expression of SREBF1 mRNA, glucosamine 6-O-sulfate results in decreased expression of SREBF1 protein CTD PMID:19520133 beta-hexachlorocyclohexane decreases expression ISO RGD:69474 6480464 beta-hexachlorocyclohexane results in decreased expression of SREBF1 mRNA CTD PMID:25270620 beta-hexachlorocyclohexane increases expression ISO RGD:69473 6480464 beta-hexachlorocyclohexane results in increased expression of SREBF1 mRNA, beta-hexachlorocyclohexane results in increased expression of SREBF1 protein CTD PMID:27203212 beta-naphthoflavone decreases expression ISO RGD:69474 6480464 beta-Naphthoflavone results in decreased expression of SREBF1 mRNA CTD PMID:23994337 betulin decreases cleavage ISO RGD:69473 6480464 betulin results in decreased cleavage of SREBF1 protein CTD PMID:29950559 betulin multiple interactions ISO RGD:69473 6480464 [Gefitinib co-treated with betulin] results in decreased expression of SREBF1 protein, betulin affects the reaction [BRAF protein affects the reaction [Vemurafenib results in decreased cleavage of SREBF1 protein]] CTD PMID:27447558 , PMID:29950559 betulin decreases expression ISO RGD:69473 6480464 betulin results in decreased expression of SREBF1 protein CTD PMID:27447558 bexarotene increases expression EXP 6480464 bexarotene results in increased expression of SREBF1 mRNA CTD PMID:23292798 bexarotene increases expression ISO RGD:69473 6480464 Bexarotene results in increased expression of SREBF1 mRNA CTD PMID:32123961 bexarotene multiple interactions ISO RGD:69473 6480464 [Bexarotene co-treated with GW 3965] results in increased expression of SREBF1 mRNA more ... CTD PMID:25932594 , PMID:32123961 bezafibrate multiple interactions ISO RGD:69473 6480464 SREBF1 protein inhibits the reaction [cerivastatin promotes the reaction [Bezafibrate results in increased activity of [PPARA protein binds to RXRA protein]]] CTD PMID:11779144 bezafibrate multiple interactions EXP 6480464 Bezafibrate inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:26190035 bezafibrate increases expression ISO RGD:69474 6480464 Bezafibrate results in increased expression of SREBF1 mRNA, Bezafibrate results in increased expression of SREBF1 protein CTD PMID:19124612 bezafibrate multiple interactions ISO RGD:69474 6480464 [Bezafibrate results in decreased expression of SREBF1] which results in decreased abundance of Triglycerides more ... CTD PMID:19124612 bezafibrate decreases expression ISO RGD:69474 6480464 Bezafibrate results in decreased expression of SREBF1 mRNA, Bezafibrate results in decreased expression of SREBF1 protein CTD PMID:19124612 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:69474 6480464 [Dietary Sucrose co-treated with Dietary Fats co-treated with bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:23756648 , PMID:30722647 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of SREBF1 protein CTD PMID:30597186 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 Diethylhexyl Phthalate promotes the reaction [Dietary Fats results in increased expression of SREBF1 mRNA], Diethylhexyl Phthalate promotes the reaction [SREBF1 protein binds to SLC2A2 promoter] CTD PMID:30597186 , PMID:33166671 bisphenol A affects expression ISO RGD:69474 6480464 bisphenol A affects the expression of SREBF1 mRNA alternative form, bisphenol A affects the expression of SREBF1 protein CTD PMID:21932408 bisphenol A decreases methylation ISO RGD:69473 6480464 bisphenol A results in decreased methylation of SREBF1 gene CTD PMID:31601247 bisphenol A affects expression ISO RGD:69473 6480464 bisphenol A affects the expression of SREBF1 mRNA CTD PMID:30903817 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of SREBF1 mRNA CTD PMID:28657538 , PMID:34947998 bisphenol A decreases methylation ISO RGD:69474 6480464 bisphenol A results in decreased methylation of SREBF1 promoter CTD PMID:27502578 , PMID:28796629 bisphenol A affects methylation ISO RGD:69474 6480464 bisphenol A affects the methylation of SREBF1 promoter CTD PMID:27334623 bisphenol A increases response to substance ISO RGD:69474 6480464 SREBF1 mRNA results in increased susceptibility to bisphenol A CTD PMID:27502578 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SREBF1 mRNA, bisphenol A results in increased expression of SREBF1 protein CTD PMID:20019905 more ... bisphenol A decreases expression ISO RGD:69474 6480464 bisphenol A results in decreased expression of SREBF1 mRNA CTD PMID:24959901 bisphenol A multiple interactions EXP 6480464 [Fructose co-treated with bisphenol A] results in increased expression of SREBF1 protein more ... CTD PMID:25112833 more ... bisphenol A multiple interactions ISO RGD:69474 6480464 [bisphenol A co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA more ... CTD PMID:23756648 more ... bisphenol A increases expression ISO RGD:69473 6480464 bisphenol A results in increased expression of SREBF1 mRNA, bisphenol A results in increased expression of SREBF1 protein CTD PMID:25047013 more ... bisphenol A multiple interactions ISO RGD:69473 6480464 [Vitamin D co-treated with bisphenol A co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] affects the expression of SREBF1 mRNA more ... CTD PMID:27014939 more ... bisphenol A increases expression ISO RGD:69474 6480464 bisphenol A results in increased expression of SREBF1 mRNA, bisphenol A results in increased expression of SREBF1 protein CTD PMID:21932408 more ... Bisphenol A diglycidyl ether decreases expression EXP 6480464 2, 2-bis(4-glycidyloxyphenyl)propane results in decreased expression of SREBF1 protein CTD PMID:22726273 boric acid multiple interactions ISO RGD:69474 6480464 boric acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of SREBF1 mRNA] CTD PMID:28285642 bromobenzene decreases expression EXP 6480464 bromobenzene results in decreased expression of SREBF1 mRNA CTD PMID:32479839 buspirone decreases expression EXP 6480464 Buspirone results in decreased expression of SREBF1 mRNA CTD PMID:24136188 buta-1,3-diene decreases expression ISO RGD:69474 6480464 1, 3-butadiene results in decreased expression of SREBF1 mRNA CTD PMID:21147608 butyric acid multiple interactions ISO RGD:69473 6480464 Butyric Acid inhibits the reaction [Lipopolysaccharides results in increased expression of SREBF1 mRNA] CTD PMID:29751049 butyric acid multiple interactions ISO RGD:69474 6480464 Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SREBF1 mRNA] CTD PMID:29751049 C60 fullerene increases expression EXP 6480464 fullerene C60 results in increased expression of SREBF1 mRNA CTD PMID:19167457 Cacalol multiple interactions ISO RGD:69473 6480464 cacalol inhibits the reaction [SREBF1 protein binds to FAS promoter] CTD PMID:20665104 Cacalol decreases expression ISO RGD:69473 6480464 cacalol results in decreased expression of SREBF1 protein CTD PMID:20665104 cadmium atom multiple interactions EXP 6480464 [Streptozocin co-treated with Cadmium] results in increased expression of SREBF1 protein, myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF1 protein] CTD PMID:25240712 cadmium atom decreases expression EXP 6480464 Cadmium results in decreased expression of SREBF1 mRNA CTD PMID:28315714 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of SREBF1 mRNA CTD PMID:25993096 cadmium dichloride increases expression ISO RGD:69474 6480464 Cadmium Chloride results in increased expression of SREBF1 mRNA CTD PMID:26352046 caffeine increases expression EXP 6480464 Caffeine results in increased expression of SREBF1 mRNA, Caffeine results in increased expression of SREBF1 protein CTD PMID:30776459 caffeine increases phosphorylation ISO RGD:69473 6480464 Caffeine results in increased phosphorylation of SREBF1 protein CTD PMID:35688186 calcitriol decreases expression ISO RGD:69474 6480464 Calcitriol results in decreased expression of SREBF1 mRNA CTD PMID:16368784 cannabidiol decreases expression ISO RGD:69474 6480464 Cannabidiol results in decreased expression of SREBF1 mRNA CTD PMID:31052254 capsaicin increases expression ISO RGD:69473 6480464 Capsaicin results in increased expression of SREBF1 mRNA CTD PMID:36044967 carbamazepine multiple interactions EXP 6480464 [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of SREBF1 mRNA, [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of SREBF1 mRNA CTD PMID:35786680 carbendazim increases expression ISO RGD:69474 6480464 carbendazim results in increased expression of SREBF1 mRNA CTD PMID:26071454 CARBENOXOLONE multiple interactions EXP 6480464 Carbenoxolone affects the reaction [Sodium Glutamate affects the expression of SREBF1 mRNA] CTD PMID:31077719 CARBENOXOLONE affects activity EXP 6480464 Carbenoxolone affects the activity of SREBF1 protein CTD PMID:31077719 carbon nanotube decreases expression ISO RGD:69474 6480464 Nanotubes more ... CTD PMID:25620056 carbon nanotube increases expression ISO RGD:69473 6480464 Nanotubes, Carbon results in increased expression of SREBF1 mRNA CTD PMID:31047983 carvedilol multiple interactions EXP 6480464 carvedilol inhibits the reaction [Ethanol results in increased expression of SREBF1 mRNA] CTD PMID:22413959 cerivastatin multiple interactions ISO RGD:69473 6480464 SREBF1 protein inhibits the reaction [cerivastatin promotes the reaction [Bezafibrate results in increased activity of [PPARA protein binds to RXRA protein]]] CTD PMID:11779144 chenodeoxycholic acid decreases expression ISO RGD:69473 6480464 Chenodeoxycholic Acid results in decreased expression of SREBF1 mRNA CTD PMID:16269825 chenodeoxycholic acid multiple interactions ISO RGD:69473 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of SREBF1 mRNA more ... CTD PMID:33819548 chenodeoxycholic acid multiple interactions ISO RGD:69474 6480464 Chenodeoxycholic Acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SREBF1 protein] more ... CTD PMID:27773935 , PMID:35780845 chitosan multiple interactions EXP 6480464 [Fish Oils co-treated with Chitosan] inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA], Chitosan inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:28987369 chloroethene increases expression ISO RGD:69474 6480464 Vinyl Chloride results in increased expression of SREBF1 mRNA CTD PMID:18579281 chlorpyrifos multiple interactions EXP 6480464 Dietary Fats promotes the reaction [Chlorpyrifos results in increased expression of SREBF1 mRNA] CTD PMID:33994353 cholate multiple interactions EXP 6480464 [cocoa butter co-treated with Cholesterol, Dietary co-treated with Cholates] results in increased expression of SREBF1 mRNA CTD PMID:25814186 cholesterol multiple interactions ISO RGD:69474 6480464 [lard co-treated with Cholesterol co-treated with Sucrose co-treated with Atrazine] results in increased expression of SREBF1 mRNA, [lard co-treated with Cholesterol co-treated with Sucrose co-treated with Ethinyl Estradiol] results in increased expression of SREBF1 mRNA CTD PMID:24440342 cholesterol multiple interactions ISO RGD:69473 6480464 [25-hydroxycholesterol co-treated with Cholesterol] results in decreased cleavage of SREBF1 protein CTD PMID:27324795 choline multiple interactions ISO RGD:69474 6480464 5-(3-methoxy-5-(4-methoxystyryl)phenoxy)-2 more ... CTD PMID:19593819 more ... choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency] results in decreased expression of SREBF1 mRNA, geraniol promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of SREBF1 mRNA] CTD PMID:26695085 ciguatoxin CTX1B affects expression ISO RGD:69474 6480464 Ciguatoxins affects the expression of SREBF1 mRNA CTD PMID:18353800 cis-caffeic acid multiple interactions ISO RGD:69473 6480464 [Metformin co-treated with caffeic acid] results in decreased expression of SREBF1 protein CTD PMID:28576465 cisplatin multiple interactions ISO RGD:69473 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of SREBF1 mRNA CTD PMID:27392435 citalopram multiple interactions ISO RGD:69473 6480464 Citalopram results in increased cleavage of and results in increased activity of SREBF1 protein CTD PMID:16324787 clavulanic acid decreases expression ISO RGD:69473 6480464 Clavulanic Acid results in decreased expression of SREBF1 mRNA CTD PMID:34767876 clofazimine increases expression EXP 6480464 Clofazimine results in increased expression of SREBF1 mRNA CTD PMID:31393584 clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of SREBF1 mRNA CTD PMID:17522070 clofibrate increases expression ISO RGD:69473 6480464 Clofibrate results in increased expression of SREBF1 mRNA CTD PMID:27089845 clofibrate decreases expression ISO RGD:69474 6480464 Clofibrate results in decreased expression of SREBF1 mRNA CTD PMID:23811191 clofibrate multiple interactions ISO RGD:69474 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of SREBF1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SREBF1 mRNA] CTD PMID:17585979 clomipramine multiple interactions ISO RGD:69473 6480464 Clomipramine results in increased cleavage of and results in increased activity of SREBF1 protein CTD PMID:16324787 clozapine increases expression ISO RGD:69473 6480464 Clozapine results in increased expression of SREBF1 mRNA CTD PMID:17052361 clozapine increases expression ISO RGD:69474 6480464 Clozapine results in increased expression of SREBF1 mRNA, Clozapine results in increased expression of SREBF1 protein CTD PMID:19682446 , PMID:20564506 clozapine multiple interactions ISO RGD:69474 6480464 Berberine inhibits the reaction [Clozapine results in increased expression of SREBF1 mRNA], Berberine inhibits the reaction [Clozapine results in increased expression of SREBF1 protein] CTD PMID:20564506 cobalt dichloride decreases expression ISO RGD:69473 6480464 cobaltous chloride results in decreased expression of SREBF1 mRNA CTD PMID:19320972 cobalt dichloride increases expression ISO RGD:69473 6480464 cobaltous chloride results in increased expression of SREBF1 mRNA CTD PMID:19376846 , PMID:22917661 copper atom multiple interactions EXP 6480464 [ATP7B protein affects the susceptibility to Copper] which affects the expression of SREBF1 mRNA more ... CTD PMID:23112546 , PMID:25813056 copper atom decreases expression ISO RGD:69474 6480464 Copper results in decreased expression of SREBF1 mRNA CTD PMID:17205981 copper atom affects localization EXP 6480464 Copper deficiency affects the localization of SREBF1 protein CTD PMID:11110846 copper atom multiple interactions ISO RGD:69473 6480464 [Disulfiram binds to Copper] which results in increased expression of SREBF1 mRNA, [NSC 689534 binds to Copper] which results in decreased expression of SREBF1 mRNA CTD PMID:20971185 , PMID:24690739 copper(0) multiple interactions EXP 6480464 [ATP7B protein affects the susceptibility to Copper] which affects the expression of SREBF1 mRNA more ... CTD PMID:23112546 , PMID:25813056 copper(0) affects localization EXP 6480464 Copper deficiency affects the localization of SREBF1 protein CTD PMID:11110846 copper(0) decreases expression ISO RGD:69474 6480464 Copper results in decreased expression of SREBF1 mRNA CTD PMID:17205981 copper(0) multiple interactions ISO RGD:69473 6480464 [Disulfiram binds to Copper] which results in increased expression of SREBF1 mRNA, [NSC 689534 binds to Copper] which results in decreased expression of SREBF1 mRNA CTD PMID:20971185 , PMID:24690739 corticosterone multiple interactions EXP 6480464 [Corticosterone co-treated with oleoyl-estrone] affects the expression of SREBF1 mRNA CTD PMID:19545626 corticosterone multiple interactions ISO RGD:69474 6480464 [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SREBF1 mRNA more ... CTD PMID:29751049 cortisol increases expression ISO RGD:69473 6480464 Hydrocortisone results in increased expression of SREBF1 mRNA CTD PMID:30776459 cortisol multiple interactions ISO RGD:69473 6480464 [Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of SREBF1 mRNA more ... CTD PMID:30776459 , PMID:33476690 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of SREBF1 mRNA CTD PMID:26577399 , PMID:27523638 curcumin decreases expression EXP 6480464 Curcumin results in decreased expression of SREBF1 mRNA CTD PMID:27208389 curcumin affects expression ISO RGD:69474 6480464 Curcumin affects the expression of SREBF1 mRNA, Curcumin affects the expression of SREBF1 protein CTD PMID:27208389 cyclosporin A decreases expression ISO RGD:69473 6480464 Cyclosporine results in decreased expression of SREBF1 mRNA CTD PMID:20106945 more ... cyclosporin A multiple interactions ISO RGD:69473 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Cyclosporine] results in decreased expression of SREBF1 mRNA CTD PMID:33819548 cyclosporin A increases expression ISO RGD:69473 6480464 Cyclosporine results in increased expression of SREBF1 mRNA CTD PMID:25562108 cyhalothrin increases expression EXP 6480464 cyhalothrin results in increased expression of SREBF1 mRNA CTD PMID:27348886 cyhalothrin multiple interactions ISO RGD:69473 6480464 [cyhalothrin co-treated with Oleic Acid] results in increased expression of SREBF1 protein, Metformin inhibits the reaction [[cyhalothrin co-treated with Oleic Acid] results in increased expression of SREBF1 protein] CTD PMID:36529352 cyhalothrin increases expression ISO RGD:69474 6480464 cyhalothrin results in increased expression of SREBF1 mRNA, cyhalothrin results in increased expression of SREBF1 protein CTD PMID:36529352 D-gluconic acid multiple interactions EXP 6480464 [[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:30031400 D-glucose multiple interactions ISO RGD:69473 6480464 [INS protein co-treated with Glucose] results in increased expression of SREBF1 mRNA more ... CTD PMID:19724016 more ... D-glucose multiple interactions ISO RGD:69474 6480464 resveratrol inhibits the reaction [Glucose results in increased expression of SREBF1 protein] CTD PMID:23090186 D-glucose increases expression ISO RGD:69474 6480464 Glucose results in increased expression of SREBF1 mRNA, Glucose results in increased expression of SREBF1 protein CTD PMID:10913129 more ... D-glucose multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased cleavage of SREBF1 protein] more ... CTD PMID:22031849 , PMID:23647015 D-glucose increases expression EXP 6480464 Glucose results in increased expression of SREBF1 protein CTD PMID:23647015 D-glucose increases expression ISO RGD:69473 6480464 Glucose results in increased expression of SREBF1 mRNA, Glucose results in increased expression of SREBF1 protein CTD PMID:23319015 , PMID:23647015 D-penicillamine multiple interactions ISO RGD:69474 6480464 Penicillamine promotes the reaction [ATP7B protein mutant form results in decreased expression of SREBF1 mRNA] CTD PMID:22945834 dabrafenib decreases cleavage ISO RGD:69473 6480464 dabrafenib results in decreased cleavage of SREBF1 protein CTD PMID:29950559 dabrafenib multiple interactions ISO RGD:69473 6480464 [BRAF protein affects the susceptibility to dabrafenib] which affects the cleavage of SREBF1 protein CTD PMID:29950559 dapagliflozin multiple interactions EXP 6480464 [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of SREBF1 protein], dapagliflozin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of SREBF1 protein] CTD PMID:32259528 DDE multiple interactions ISO RGD:69473 6480464 Dichlorodiphenyl Dichloroethylene promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA] CTD PMID:26200599 DDE increases expression ISO RGD:69473 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of SREBF1 protein CTD PMID:27203212 decabromodiphenyl ether multiple interactions ISO RGD:69474 6480464 decabromobiphenyl ether promotes the reaction [[osteum co-treated with Palmitic Acid] results in increased expression of SREBF1 protein] CTD PMID:34757160 deoxycholic acid multiple interactions ISO RGD:69473 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of SREBF1 mRNA more ... CTD PMID:33819548 deoxypodophyllotoxin multiple interactions ISO RGD:69474 6480464 deoxypodophyllotoxin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 protein] CTD PMID:30148990 deoxypodophyllotoxin multiple interactions ISO RGD:69473 6480464 deoxypodophyllotoxin inhibits the reaction [T0901317 results in increased expression of SREBF1 mRNA] more ... CTD PMID:30148990 depsipeptide multiple interactions ISO RGD:69473 6480464 [decitabine co-treated with Depsipeptides] results in increased expression of SREBF1 mRNA CTD PMID:17064661 depsipeptide increases expression ISO RGD:69473 6480464 Depsipeptides results in increased expression of SREBF1 mRNA CTD PMID:17064661 desferrioxamine B multiple interactions ISO RGD:69473 6480464 [Paclitaxel co-treated with FV-429 compound co-treated with Deferoxamine] promotes the reaction [Oxygen deficiency results in increased expression of SREBF1 protein] CTD PMID:34648812 desmosterol increases expression ISO RGD:69474 6480464 Desmosterol results in increased expression of SREBF1 mRNA, Desmosterol results in increased expression of SREBF1 protein CTD PMID:19260826 dexamethasone multiple interactions ISO RGD:69474 6480464 14-deoxy-11 more ... CTD PMID:11101056 more ... dexamethasone decreases expression ISO RGD:69474 6480464 Dexamethasone results in decreased expression of SREBF1 mRNA CTD PMID:31053639 dexamethasone multiple interactions ISO RGD:69473 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA more ... CTD PMID:25932594 more ... dexamethasone increases expression ISO RGD:69473 6480464 Dexamethasone results in increased expression of SREBF1 mRNA CTD PMID:25047013 , PMID:27003841 diallyl disulfide multiple interactions ISO RGD:69474 6480464 diallyl disulfide inhibits the reaction [Ethanol results in increased expression of SREBF1 protein] CTD PMID:35526736 Diallyl sulfide multiple interactions ISO RGD:69474 6480464 allyl sulfide inhibits the reaction [Ethanol results in increased expression of SREBF1 protein] CTD PMID:22138249 Diallyl sulfide multiple interactions ISO RGD:69473 6480464 allyl sulfide inhibits the reaction [Ethanol results in increased expression of SREBF1 protein] CTD PMID:22138249 diarsenic trioxide multiple interactions ISO RGD:69473 6480464 [22-hydroxycholesterol co-treated with Alitretinoin] inhibits the reaction [Arsenic Trioxide results in decreased expression of SREBF1 protein] CTD PMID:27622732 diarsenic trioxide decreases expression ISO RGD:69473 6480464 Arsenic Trioxide results in decreased expression of SREBF1 mRNA, Arsenic Trioxide results in decreased expression of SREBF1 protein CTD PMID:20339114 more ... diarsenic trioxide decreases expression ISO RGD:69474 6480464 Arsenic Trioxide results in decreased expression of SREBF1 mRNA, Arsenic Trioxide results in decreased expression of SREBF1 protein CTD PMID:20339114 , PMID:30237538 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of SREBF1 mRNA CTD PMID:21266533 dibutyl phthalate increases expression ISO RGD:69473 6480464 Dibutyl Phthalate results in increased expression of SREBF1 protein CTD PMID:33508418 dibutyl phthalate multiple interactions ISO RGD:69473 6480464 [Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of SREBF1 protein more ... CTD PMID:33508418 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of SREBF1 protein CTD PMID:33508418 dibutyl phthalate multiple interactions EXP 6480464 Dibutyl Phthalate promotes the reaction [Dietary Fats results in increased expression of SREBF1 protein] CTD PMID:33508418 dichloroacetic acid increases expression ISO RGD:69474 6480464 Dichloroacetic Acid results in increased expression of SREBF1 mRNA CTD PMID:28962523 diethyl maleate decreases expression EXP 6480464 diethyl maleate results in decreased expression of SREBF1 mRNA CTD PMID:21161181 diethylstilbestrol multiple interactions ISO RGD:69474 6480464 2-chloro-5-nitrobenzanilide inhibits the reaction [Diethylstilbestrol results in increased expression of SREBF1 protein] CTD PMID:22710028 diethylstilbestrol increases expression ISO RGD:69474 6480464 Diethylstilbestrol results in increased expression of SREBF1 mRNA, Diethylstilbestrol results in increased expression of SREBF1 protein CTD PMID:22710028 dihydroartemisinin multiple interactions EXP 15036816 Dihydroartemisinin inhibits the reaction [ethanol increases expression of Srebf1 mRNA and protein in liver] RGD dihydroartemisinin multiple interactions ISO RGD:69473 6480464 [artenimol co-treated with NR1H4 protein] inhibits the reaction [Ethanol results in increased expression of SREBF1 mRNA] more ... CTD PMID:27939985 dimethyl sulfoxide increases expression EXP 15092090 DMSO increases expression of Srebf1 mRNA in rat liver, reaction inhibited by INT-767 RGD dioxygen multiple interactions ISO RGD:69473 6480464 [FV-429 compound co-treated with Oxygen deficiency] affects the expression of SREBF1 protein more ... CTD PMID:24503013 , PMID:34648812 dioxygen increases expression ISO RGD:69473 6480464 Oxygen deficiency results in increased expression of SREBF1 mRNA, Oxygen deficiency results in increased expression of SREBF1 protein CTD PMID:34648812 dioxygen decreases expression ISO RGD:69473 6480464 Oxygen deficiency results in decreased expression of SREBF1 protein CTD PMID:24503013 disodium selenite decreases methylation ISO RGD:69474 6480464 Sodium Selenite results in decreased methylation of SREBF1 exon CTD PMID:28810182 disodium selenite multiple interactions ISO RGD:69474 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA] CTD PMID:36464106 disodium selenite multiple interactions EXP 6480464 [[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:30031400 disodium selenite increases expression ISO RGD:69474 6480464 Sodium Selenite results in increased expression of SREBF1 mRNA CTD PMID:28810182 disulfiram multiple interactions ISO RGD:69473 6480464 [Disulfiram binds to Copper] which results in increased expression of SREBF1 mRNA CTD PMID:24690739 dorsomorphin multiple interactions ISO RGD:69473 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:23319015 more ... dorsomorphin multiple interactions EXP 6480464 dorsomorphin inhibits the reaction [Resveratrol metabolite inhibits the reaction [T0901317 results in increased expression of SREBF1 mRNA]] CTD PMID:24633463 dorsomorphin multiple interactions ISO RGD:69474 6480464 dorsomorphin inhibits the reaction [cinnamaldehyde results in decreased expression of SREBF1 mRNA] CTD PMID:21401097 doxorubicin decreases expression ISO RGD:69473 6480464 Doxorubicin results in decreased expression of SREBF1 mRNA CTD PMID:29803840 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of SREBF1 mRNA CTD PMID:32289291 efavirenz decreases expression ISO RGD:69473 6480464 efavirenz results in decreased expression of SREBF1 mRNA CTD PMID:21619898 elemental selenium increases expression ISO RGD:69474 6480464 Selenium results in increased expression of SREBF1 mRNA CTD PMID:28810182 elemental selenium multiple interactions ISO RGD:69474 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA] CTD PMID:36464106 elemental selenium multiple interactions EXP 6480464 [[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:30031400 elemental selenium increases expression EXP 6480464 Selenium results in increased expression of SREBF1 mRNA CTD PMID:19022953 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of SREBF1 mRNA CTD PMID:29391264 entinostat increases expression ISO RGD:69473 6480464 entinostat results in increased expression of SREBF1 mRNA CTD PMID:26272509 entinostat multiple interactions ISO RGD:69473 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SREBF1 mRNA CTD PMID:27188386 erythromycin A multiple interactions ISO RGD:69474 6480464 [Penicillin G co-treated with Erythromycin] results in increased expression of SREBF1 mRNA CTD PMID:27503388 erythromycin A increases expression ISO RGD:69474 6480464 Erythromycin results in increased expression of SREBF1 mRNA CTD PMID:27503388 erythromycin estolate decreases expression EXP 6480464 Erythromycin Estolate results in decreased expression of SREBF1 mRNA CTD PMID:17522070 ethanol multiple interactions ISO RGD:69474 6480464 5 more ... CTD PMID:12036955 more ... ethanol decreases expression ISO RGD:69473 6480464 Ethanol results in decreased expression of SREBF1 protein CTD PMID:28062356 ethanol increases expression EXP 15036816 ethanol increases expression of Srebf1 mRNA and protein in liver RGD ethanol increases expression EXP 6480464 Ethanol results in increased expression of SREBF1 mRNA, Ethanol results in increased expression of SREBF1 protein CTD PMID:12036955 more ... ethanol increases expression ISO RGD:69474 6480464 Ethanol results in increased expression of SREBF1 mRNA, Ethanol results in increased expression of SREBF1 protein CTD PMID:18620774 more ... ethanol increases expression ISO RGD:69473 6480464 Ethanol results in increased expression of SREBF1 mRNA, Ethanol results in increased expression of SREBF1 protein CTD PMID:22138249 more ... ethanol multiple interactions ISO RGD:69473 6480464 5 more ... CTD PMID:22138249 more ... ethanol affects localization EXP 6480464 Ethanol affects the localization of SREBF1 protein CTD PMID:19371623 ethanol decreases expression ISO RGD:69474 6480464 Ethanol results in decreased expression of SREBF1 mRNA CTD PMID:22173916 , PMID:28882574 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of SREBF1 mRNA CTD PMID:16098508 ethanol increases activity ISO RGD:69474 6480464 Ethanol results in increased activity of SREBF1 protein CTD PMID:18620774 ethanol multiple interactions EXP 6480464 [Dietary Fats co-treated with Ethanol] results in increased expression of SREBF1 mRNA more ... CTD PMID:18239056 more ... ethyl methanesulfonate decreases expression ISO RGD:69473 6480464 Ethyl Methanesulfonate results in decreased expression of SREBF1 mRNA CTD PMID:23649840 ezetimibe decreases expression ISO RGD:69473 6480464 Ezetimibe results in decreased expression of SREBF1 mRNA CTD PMID:16177187 fenofibrate multiple interactions ISO RGD:69473 6480464 Fenofibrate inhibits the reaction [Fatty Acids more ... CTD PMID:24735863 fenofibrate multiple interactions EXP 6480464 [Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of SREBF1 mRNA] CTD PMID:26973390 fenofibrate increases expression ISO RGD:69474 6480464 Fenofibrate results in increased expression of SREBF1 mRNA CTD PMID:23063693 fenofibrate multiple interactions ISO RGD:69474 6480464 Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SREBF1 mRNA] more ... CTD PMID:19593819 , PMID:23063693 fentin chloride multiple interactions ISO RGD:69473 6480464 [triphenyltin chloride results in increased abundance of triphenyltin] which results in increased expression of SREBF1 mRNA CTD PMID:35998708 folic acid affects localization ISO RGD:69474 6480464 Folic Acid affects the localization of SREBF1 protein CTD PMID:25733650 formaldehyde decreases expression ISO RGD:69473 6480464 Formaldehyde results in decreased expression of SREBF1 mRNA CTD PMID:23649840 fructose multiple interactions ISO RGD:69474 6480464 Phenylbutyrates inhibits the reaction [Fructose affects the localization of SREBF1 protein alternative form] more ... CTD PMID:15066988 , PMID:22698815 fructose increases expression ISO RGD:69474 6480464 Fructose results in increased expression of SREBF1 mRNA, Fructose results in increased expression of SREBF1 protein CTD PMID:10913129 more ... fructose affects localization ISO RGD:69474 6480464 Fructose affects the localization of SREBF1 protein alternative form CTD PMID:22698815 fructose increases expression EXP 6480464 Fructose results in increased expression of SREBF1 mRNA, Fructose results in increased expression of SREBF1 protein CTD PMID:11934685 more ... fructose multiple interactions EXP 6480464 [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of SREBF1 protein] more ... CTD PMID:17188681 more ... fructose affects response to substance ISO RGD:69474 6480464 SREBF1 promoter SNP affects the susceptibility to Fructose CTD PMID:15123654 fumonisin B1 decreases expression ISO RGD:69474 6480464 fumonisin B1 results in decreased expression of SREBF1 mRNA CTD PMID:16221962 furan decreases expression EXP 6480464 furan results in decreased expression of SREBF1 mRNA CTD PMID:26194646 gadolinium trichloride multiple interactions EXP 6480464 gadolinium chloride inhibits the reaction [[Fructose co-treated with Copper deficiency] results in increased expression of SREBF1 protein] CTD PMID:25813056 galactose increases expression ISO RGD:69474 6480464 Galactose results in increased expression of SREBF1 mRNA CTD PMID:10913129 gamma-hexachlorocyclohexane decreases expression EXP 6480464 Hexachlorocyclohexane results in decreased expression of SREBF1 mRNA CTD PMID:17785943 Ganoderic acid A decreases expression ISO RGD:69473 6480464 ganoderic acid A results in decreased expression of SREBF1 mRNA, ganoderic acid A results in decreased expression of SREBF1 protein CTD PMID:29852127 Ganoderic acid A multiple interactions ISO RGD:69474 6480464 [Dietary Fats co-treated with ganoderic acid A] affects the expression of SREBF1 mRNA, [Dietary Fats co-treated with ganoderic acid A] affects the expression of SREBF1 protein CTD PMID:29852127 Gastrodin multiple interactions ISO RGD:69474 6480464 gastrodin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:26634892 gefitinib multiple interactions ISO RGD:69473 6480464 [Gefitinib co-treated with betulin] results in decreased expression of SREBF1 protein CTD PMID:27447558 genistein multiple interactions ISO RGD:69474 6480464 [Genistein co-treated with mono-(2-ethylhexyl)phthalate] affects the expression of SREBF1 mRNA CTD PMID:27181934 genistein multiple interactions ISO RGD:69473 6480464 Genistein inhibits the reaction [T0901317 results in increased expression of SREBF1 protein] CTD PMID:29702089 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of SREBF1 mRNA CTD PMID:33387578 geraniol multiple interactions EXP 6480464 geraniol promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of SREBF1 mRNA] CTD PMID:26695085 ginsenoside Re multiple interactions ISO RGD:69474 6480464 ginsenoside Re inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:21971952 ginsenoside Re decreases expression ISO RGD:69473 6480464 ginsenoside Re results in decreased expression of SREBF1 mRNA CTD PMID:21971952 Ginsenoside Rh4 multiple interactions ISO RGD:69474 6480464 ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SREBF1 mRNA] CTD PMID:33359794 glucagon multiple interactions ISO RGD:69474 6480464 Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA], Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased expression of SREBF1 mRNA] CTD PMID:29988851 glucose multiple interactions ISO RGD:69473 6480464 [INS protein co-treated with Glucose] results in increased expression of SREBF1 mRNA more ... CTD PMID:19724016 more ... glucose multiple interactions ISO RGD:69474 6480464 resveratrol inhibits the reaction [Glucose results in increased expression of SREBF1 protein] CTD PMID:23090186 glucose increases expression ISO RGD:69474 6480464 Glucose results in increased expression of SREBF1 mRNA, Glucose results in increased expression of SREBF1 protein CTD PMID:10913129 more ... glucose multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased cleavage of SREBF1 protein] more ... CTD PMID:22031849 , PMID:23647015 glucose increases expression EXP 6480464 Glucose results in increased expression of SREBF1 protein CTD PMID:23647015 glucose increases expression ISO RGD:69473 6480464 Glucose results in increased expression of SREBF1 mRNA, Glucose results in increased expression of SREBF1 protein CTD PMID:23319015 , PMID:23647015 glutathione multiple interactions ISO RGD:69474 6480464 Glutathione inhibits the reaction [Alcohols results in increased expression of SREBF1 protein] CTD PMID:28803762 glycerol 2-phosphate multiple interactions ISO RGD:69473 6480464 [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA more ... CTD PMID:25932594 glycochenodeoxycholic acid multiple interactions ISO RGD:69473 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of SREBF1 mRNA more ... CTD PMID:33819548 glycocholic acid multiple interactions ISO RGD:69473 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of SREBF1 mRNA more ... CTD PMID:33819548 glycodeoxycholic acid multiple interactions ISO RGD:69473 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of SREBF1 mRNA more ... CTD PMID:33819548 glyphosate increases expression ISO RGD:69474 6480464 glyphosate results in increased expression of SREBF1 mRNA CTD PMID:31374489 gold atom multiple interactions ISO RGD:69473 6480464 [Polyethyleneimine binds to Gold] which results in decreased expression of SREBF1 mRNA CTD PMID:28433809 gold atom decreases expression ISO RGD:69473 6480464 Gold analog results in decreased expression of SREBF1 mRNA CTD PMID:36057382 gold(0) multiple interactions ISO RGD:69473 6480464 [Polyethyleneimine binds to Gold] which results in decreased expression of SREBF1 mRNA CTD PMID:28433809 gold(0) decreases expression ISO RGD:69473 6480464 Gold analog results in decreased expression of SREBF1 mRNA CTD PMID:36057382 guggulsterone multiple interactions EXP 15036816 Z-guggulsterone reverses the reaction [Dihydroartemisinin inhibits the reaction [ethanol increases expression of Srebf1 mRNA and protein in liver]] RGD guggulsterone multiple interactions ISO RGD:69474 6480464 pregna-4 more ... CTD PMID:27773935 GW 3965 multiple interactions ISO RGD:69473 6480464 [Bexarotene co-treated with GW 3965] results in increased expression of SREBF1 mRNA more ... CTD PMID:23651738 more ... GW 3965 multiple interactions ISO RGD:69474 6480464 GW 3965 inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 mRNA], GW 3965 inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein] CTD PMID:31421115 GW 3965 increases expression EXP 6480464 GW 3965 results in increased expression of SREBF1 mRNA CTD PMID:28315714 GW 3965 increases expression ISO RGD:69473 6480464 GW 3965 results in increased expression of SREBF1 mRNA, GW 3965 results in increased expression of SREBF1 protein CTD PMID:16107141 more ... GW 4064 decreases expression ISO RGD:69473 6480464 GW 4064 results in decreased expression of SREBF1 mRNA CTD PMID:16269825 GW 4064 multiple interactions ISO RGD:69473 6480464 [GW 4064 co-treated with Oleic Acid] results in decreased expression of SREBF1 mRNA CTD PMID:30611723 GW 6471 multiple interactions ISO RGD:69473 6480464 GW 6471 inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of SREBF1 protein], GW 6471 inhibits the reaction [Dibutyl Phthalate results in increased expression of SREBF1 protein] CTD PMID:33508418 GW 7647 multiple interactions ISO RGD:69473 6480464 [GW 7647 co-treated with Oleic Acid] results in decreased expression of SREBF1 mRNA CTD PMID:30611723 herbacetin multiple interactions ISO RGD:69474 6480464 herbacetin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:29653099 hexadecanoic acid multiple interactions ISO RGD:69473 6480464 [Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 protein more ... CTD PMID:25943029 more ... hexadecanoic acid decreases expression ISO RGD:69474 6480464 Palmitic Acid results in decreased expression of SREBF1 mRNA CTD PMID:34968464 hexadecanoic acid multiple interactions ISO RGD:69474 6480464 [osteum co-treated with Palmitic Acid] results in increased expression of SREBF1 protein more ... CTD PMID:30208301 more ... hexadecanoic acid increases expression ISO RGD:69474 6480464 Palmitic Acid results in increased expression of SREBF1 mRNA more ... CTD PMID:29414781 more ... hexadecanoic acid multiple interactions EXP 6480464 [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased expression of SREBF1 protein more ... CTD PMID:26190035 , PMID:26854922 hexadecanoic acid increases expression ISO RGD:69473 6480464 Palmitic Acid results in increased expression of SREBF1 protein CTD PMID:25943029 , PMID:30208301 Honokiol decreases expression EXP 6480464 honokiol results in decreased expression of SREBF1 mRNA CTD PMID:19371623 Honokiol multiple interactions EXP 6480464 honokiol inhibits the reaction [Ethanol affects the localization of SREBF1 protein] more ... CTD PMID:19371623 Honokiol affects localization EXP 6480464 honokiol affects the localization of SREBF1 protein CTD PMID:19371623 hydrazines decreases expression ISO RGD:69474 6480464 Hydrazines results in decreased expression of SREBF1 mRNA CTD PMID:21647536 hydrogen peroxide increases expression ISO RGD:69473 6480464 Hydrogen Peroxide results in increased expression of SREBF1 mRNA CTD PMID:29317476 imidacloprid increases expression ISO RGD:69474 6480464 imidacloprid results in increased expression of SREBF1 mRNA CTD PMID:27960282 imipramine multiple interactions ISO RGD:69473 6480464 Imipramine results in increased cleavage of and results in increased activity of SREBF1 protein CTD PMID:16324787 indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of SREBF1 mRNA CTD PMID:21396975 isosilybin multiple interactions ISO RGD:69473 6480464 isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 protein] more ... CTD PMID:36347319 isosilybin decreases expression ISO RGD:69473 6480464 isosilybin results in decreased expression of SREBF1 mRNA CTD PMID:36347319 kahweol multiple interactions ISO RGD:69473 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [kahweol results in decreased expression of SREBF1 protein], kahweol promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of SREBF1 protein] CTD PMID:30205135 kahweol decreases expression ISO RGD:69473 6480464 kahweol results in decreased expression of SREBF1 mRNA, kahweol results in decreased expression of SREBF1 protein CTD PMID:30205135 ketamine increases expression EXP 6480464 Ketamine results in increased expression of SREBF1 mRNA CTD PMID:20080153 ketotifen increases expression ISO RGD:69473 6480464 Ketotifen results in increased expression of SREBF1 mRNA CTD PMID:27089845 L-ascorbic acid multiple interactions ISO RGD:69473 6480464 [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA more ... CTD PMID:25932594 L-methionine multiple interactions ISO RGD:69474 6480464 5-(3-methoxy-5-(4-methoxystyryl)phenoxy)-2 more ... CTD PMID:19593819 more ... L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency] results in decreased expression of SREBF1 mRNA, geraniol promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of SREBF1 mRNA] CTD PMID:26695085 L-serine decreases expression ISO RGD:69473 6480464 Serine results in decreased expression of SREBF1 mRNA CTD PMID:29098664 lead diacetate increases expression ISO RGD:69473 6480464 lead acetate results in increased expression of SREBF1 protein CTD PMID:34842334 lead diacetate multiple interactions ISO RGD:69473 6480464 SRT1720 inhibits the reaction [lead acetate results in increased expression of SREBF1 protein] CTD PMID:34842334 linoleic acid decreases expression EXP 6480464 Linoleic Acid results in decreased expression of SREBF1 mRNA CTD PMID:14563831 lipoic acid multiple interactions EXP 6480464 Thioctic Acid inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:22464149 lipopolysaccharide affects localization ISO RGD:69474 6480464 Lipopolysaccharides affects the localization of SREBF1 protein CTD PMID:21689150 lipopolysaccharide multiple interactions ISO RGD:69473 6480464 [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of SREBF1 mRNA, Butyric Acid inhibits the reaction [Lipopolysaccharides results in increased expression of SREBF1 mRNA] CTD PMID:29751049 , PMID:35877022 lipopolysaccharide increases expression ISO RGD:69473 6480464 Lipopolysaccharides results in increased expression of SREBF1 mRNA, Lipopolysaccharides results in increased expression of SREBF1 protein CTD PMID:29751049 , PMID:33677747 lipopolysaccharide multiple interactions ISO RGD:69474 6480464 Melatonin inhibits the reaction [Lipopolysaccharides affects the localization of SREBF1 protein] CTD PMID:21689150 lipopolysaccharide decreases expression ISO RGD:69474 6480464 Lipopolysaccharides results in decreased expression of SREBF1 mRNA CTD PMID:16847310 lithocholic acid multiple interactions ISO RGD:69474 6480464 Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of SREBF1 mRNA] CTD PMID:20359477 lithocholic acid decreases expression ISO RGD:69474 6480464 Lithocholic Acid results in decreased expression of SREBF1 mRNA CTD PMID:20359477 losartan multiple interactions EXP 6480464 Losartan inhibits the reaction [AGT protein results in increased cleavage of SREBF1 protein] more ... CTD PMID:19109942 , PMID:25398788 lovastatin multiple interactions ISO RGD:69474 6480464 [Dietary Fats co-treated with Lovastatin] affects the expression of SREBF1 mRNA CTD PMID:29852127 lovastatin increases expression ISO RGD:69473 6480464 Lovastatin results in increased expression of SREBF1 mRNA CTD PMID:32739440 luteolin multiple interactions ISO RGD:69474 6480464 Luteolin inhibits the reaction [Tunicamycin results in increased expression of SREBF1 mRNA] CTD PMID:32407927 LY294002 multiple interactions ISO RGD:69473 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [FGF7 protein results in increased expression of SREBF1 protein] more ... CTD PMID:16162944 , PMID:30205135 LY294002 decreases expression ISO RGD:69473 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of SREBF1 protein CTD PMID:30205135 LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [AGT protein results in increased cleavage of SREBF1 protein], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased cleavage of SREBF1 protein] CTD PMID:22031849 , PMID:25398788 magnesium atom multiple interactions EXP 6480464 [[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:30031400 Magnolol affects localization EXP 6480464 magnolol affects the localization of SREBF1 protein CTD PMID:19371623 melatonin multiple interactions ISO RGD:69474 6480464 Melatonin inhibits the reaction [Lipopolysaccharides affects the localization of SREBF1 protein] CTD PMID:21689150 metformin multiple interactions ISO RGD:69473 6480464 [Metformin co-treated with caffeic acid] results in decreased expression of SREBF1 protein, Metformin inhibits the reaction [[cyhalothrin co-treated with Oleic Acid] results in increased expression of SREBF1 protein] CTD PMID:28576465 , PMID:36529352 metformin decreases expression EXP 6480464 Metformin results in decreased expression of SREBF1 mRNA CTD PMID:31324951 metformin multiple interactions EXP 6480464 Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA], Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 protein] CTD PMID:31100278 methyl methanesulfonate decreases expression ISO RGD:69473 6480464 Methyl Methanesulfonate results in decreased expression of SREBF1 mRNA CTD PMID:23649840 metronidazole multiple interactions ISO RGD:69474 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA], [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA CTD PMID:36464106 mevastatin increases cleavage ISO RGD:69474 6480464 mevastatin results in increased cleavage of SREBF1 protein CTD PMID:16330322 mevastatin multiple interactions ISO RGD:69474 6480464 EIF2S1 protein modified form inhibits the reaction [mevastatin results in increased cleavage of SREBF1 protein] CTD PMID:16330322 mevastatin decreases expression EXP 6480464 mevastatin results in decreased expression of SREBF1 protein CTD PMID:17526932 microcystin-LR decreases expression ISO RGD:69474 6480464 cyanoginosin LR results in decreased expression of SREBF1 mRNA CTD PMID:17654400 miquelianin multiple interactions EXP 6480464 quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA], quercetin 3-O-glucuronide inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:26190035 mirtazapine multiple interactions ISO RGD:69473 6480464 mirtazapine results in increased cleavage of and results in increased activity of SREBF1 protein CTD PMID:16324787 mono(2-ethylhexyl) phthalate increases expression ISO RGD:69473 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of SREBF1 mRNA CTD PMID:23118965 mono(2-ethylhexyl) phthalate affects expression ISO RGD:69474 6480464 mono-(2-ethylhexyl)phthalate affects the expression of SREBF1 mRNA CTD PMID:27181934 mono(2-ethylhexyl) phthalate multiple interactions ISO RGD:69474 6480464 [Genistein co-treated with mono-(2-ethylhexyl)phthalate] affects the expression of SREBF1 mRNA CTD PMID:27181934 monocrotophos increases expression EXP 6480464 Monocrotophos results in increased expression of SREBF1 mRNA CTD PMID:32267039 monosodium L-glutamate increases expression ISO RGD:69474 6480464 Sodium Glutamate results in increased expression of SREBF1 mRNA, Sodium Glutamate results in increased expression of SREBF1 protein CTD PMID:19724016 monosodium L-glutamate affects expression EXP 6480464 Sodium Glutamate affects the expression of SREBF1 mRNA CTD PMID:31077719 monosodium L-glutamate multiple interactions ISO RGD:69474 6480464 3-(4-(4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl)pyrrolidin-2-ylcarbonyl)thiazolidine affects the reaction [[Dietary Fats co-treated with Sodium Glutamate] affects the expression of SREBF1 mRNA] more ... CTD PMID:19001666 more ... monosodium L-glutamate multiple interactions EXP 6480464 Carbenoxolone affects the reaction [Sodium Glutamate affects the expression of SREBF1 mRNA] CTD PMID:31077719 monosodium L-glutamate decreases expression EXP 6480464 Sodium Glutamate results in decreased expression of SREBF1 mRNA CTD PMID:26092479 Morroniside affects expression ISO RGD:69474 6480464 morroniside affects the expression of SREBF1 protein CTD PMID:20487222 Muraglitazar increases expression EXP 6480464 muraglitazar results in increased expression of SREBF1 mRNA CTD PMID:21515302 myricetin multiple interactions EXP 6480464 myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF1 protein] CTD PMID:25240712 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO RGD:69473 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [CGA protein results in increased cleavage of SREBF1 protein] CTD PMID:26125464 N-methylformamide decreases expression ISO RGD:69474 6480464 methylformamide analog results in decreased expression of SREBF1 mRNA, methylformamide results in decreased expression of SREBF1 mRNA CTD PMID:17040096 N-methylnicotinate multiple interactions ISO RGD:69473 6480464 ATG7 protein affects the reaction [trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]], trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein] CTD PMID:30208301 N-methylnicotinate multiple interactions ISO RGD:69474 6480464 trigonelline inhibits the reaction [[Cholesterol more ... CTD PMID:30208301 N-nitrosodiethylamine decreases expression ISO RGD:69473 6480464 Diethylnitrosamine results in decreased expression of SREBF1 mRNA CTD PMID:21527772 N-nitrosodimethylamine decreases expression EXP 6480464 Dimethylnitrosamine results in decreased expression of SREBF1 mRNA CTD PMID:25380136 N-Nitrosopyrrolidine decreases expression ISO RGD:69473 6480464 N-Nitrosopyrrolidine results in decreased expression of SREBF1 mRNA CTD PMID:32234424 naloxone decreases expression EXP 6480464 Naloxone results in decreased expression of SREBF1 mRNA CTD PMID:17522070 naringin multiple interactions ISO RGD:69474 6480464 naringin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:22198281 nefazodone decreases expression EXP 6480464 nefazodone results in decreased expression of SREBF1 mRNA CTD PMID:24136188 nefazodone multiple interactions ISO RGD:69473 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of SREBF1 mRNA CTD PMID:33819548 nelfinavir affects localization ISO RGD:69473 6480464 Nelfinavir affects the localization of SREBF1 protein CTD PMID:21355074 nelfinavir increases expression ISO RGD:69473 6480464 Nelfinavir results in increased expression of SREBF1 protein CTD PMID:16940799 nelfinavir decreases expression ISO RGD:69473 6480464 Nelfinavir results in decreased expression of SREBF1 protein alternative form CTD PMID:21355074 nelfinavir multiple interactions ISO RGD:69473 6480464 Nelfinavir inhibits the reaction [MBTPS2 protein results in increased cleavage of and results in increased activity of SREBF1 protein] CTD PMID:21355074 nelfinavir decreases cleavage ISO RGD:69473 6480464 Nelfinavir results in decreased cleavage of SREBF1 protein CTD PMID:21355074 nelfinavir increases stability ISO RGD:69473 6480464 Nelfinavir results in increased stability of SREBF1 protein CTD PMID:21355074 neomycin multiple interactions ISO RGD:69474 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA], [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA CTD PMID:36464106 nevirapine increases expression ISO RGD:69473 6480464 Nevirapine results in increased expression of SREBF1 mRNA CTD PMID:21619898 nevirapine decreases expression EXP 6480464 Nevirapine metabolite results in decreased expression of SREBF1 mRNA CTD PMID:23947594 nicotinamide multiple interactions ISO RGD:69473 6480464 Niacinamide inhibits the reaction [platycodin D inhibits the reaction [Glucose results in increased expression of SREBF1 protein]] CTD PMID:23319015 nicotine decreases expression ISO RGD:69473 6480464 Nicotine results in decreased expression of SREBF1 mRNA CTD PMID:18247414 nicotine increases expression ISO RGD:69474 6480464 Nicotine results in increased expression of SREBF1 mRNA CTD PMID:31622651 nicotine multiple interactions EXP 6480464 [Nicotine results in increased abundance of Cotinine] which results in increased expression of SREBF1 mRNA CTD PMID:29617909 nicotine increases expression EXP 6480464 Nicotine results in increased expression of SREBF1 mRNA CTD PMID:29155039 nimesulide decreases expression EXP 6480464 nimesulide results in decreased expression of SREBF1 mRNA CTD PMID:24136188 O-methyleugenol decreases expression ISO RGD:69473 6480464 methyleugenol results in decreased expression of SREBF1 mRNA CTD PMID:32234424 obeticholic acid multiple interactions EXP 15036816 Obeticholic acid inhibits the reaction [ethanol increases expression of Srebf1 mRNA and protein in liver] RGD obeticholic acid decreases expression ISO RGD:69473 6480464 obeticholic acid results in decreased expression of SREBF1 mRNA CTD PMID:27939613 obeticholic acid multiple interactions ISO RGD:69473 6480464 obeticholic acid inhibits the reaction [Ethanol results in increased expression of SREBF1 protein] CTD PMID:27939985 olanzapine multiple interactions ISO RGD:69474 6480464 olanzapine promotes the reaction [SREBF1 protein results in increased expression of LDLR mRNA], olanzapine results in increased activity of and results in increased expression of SREBF1 protein CTD PMID:17651982 olanzapine increases expression ISO RGD:69474 6480464 olanzapine results in increased expression of SREBF1 mRNA CTD PMID:17651982 olaparib multiple interactions ISO RGD:69474 6480464 [Dietary Fats co-treated with olaparib] results in decreased expression of SREBF1 mRNA CTD PMID:27984176 oleanolic acid multiple interactions ISO RGD:69473 6480464 Oleanolic Acid promotes the reaction [NFE2L2 protein results in increased expression of SREBF1 mRNA] CTD PMID:28796629 oleic acid increases expression EXP 6480464 Oleic Acid results in increased expression of SREBF1 mRNA CTD PMID:23395669 oleic acid multiple interactions ISO RGD:69474 6480464 [N-(oxo-5 more ... CTD PMID:30165350 oleic acid increases expression ISO RGD:69473 6480464 Oleic Acid results in increased expression of SREBF1 mRNA, Oleic Acid results in increased expression of SREBF1 protein CTD PMID:31730885 oleic acid multiple interactions EXP 6480464 [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased expression of SREBF1 protein more ... CTD PMID:23395669 more ... oleic acid multiple interactions ISO RGD:69473 6480464 [6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:23603006 more ... oleic acid decreases expression ISO RGD:69473 6480464 Oleic Acid results in decreased expression of SREBF1 mRNA, Oleic Acid results in decreased expression of SREBF1 protein CTD PMID:15949695 more ... oleuropein multiple interactions EXP 6480464 oleuropein inhibits the reaction [Cholesterol, Dietary results in increased expression of SREBF1 protein] CTD PMID:27019295 Olmesartan medoxomil decreases expression EXP 6480464 Olmesartan Medoxomil results in decreased expression of SREBF1 mRNA CTD PMID:18501344 orlistat multiple interactions ISO RGD:69473 6480464 Orlistat inhibits the reaction [[AKT1 gene mutant form co-treated with MET gene mutant form] results in increased expression of SREBF1 protein] CTD PMID:32045588 orlistat decreases expression ISO RGD:69473 6480464 Orlistat results in decreased expression of SREBF1 protein CTD PMID:32045588 oroxylin A multiple interactions ISO RGD:69474 6480464 5 more ... CTD PMID:29476730 oroxylin A multiple interactions ISO RGD:69473 6480464 5 more ... CTD PMID:29476730 ozone decreases expression EXP 6480464 Ozone results in decreased expression of SREBF1 mRNA CTD PMID:25838073 ozone multiple interactions ISO RGD:69473 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of SREBF1 mRNA more ... CTD PMID:32699268 p-menthan-3-ol decreases expression ISO RGD:69473 6480464 Menthol results in decreased expression of SREBF1 mRNA CTD PMID:26760959 p-tert-Amylphenol decreases expression EXP 6480464 4-tert-octylphenol results in decreased expression of SREBF1 mRNA, 4-tert-octylphenol results in decreased expression of SREBF1 protein CTD PMID:26164745 paclitaxel multiple interactions ISO RGD:69473 6480464 [FV-429 compound co-treated with Paclitaxel] inhibits the reaction [Oxygen deficiency results in increased expression of SREBF1 protein] more ... CTD PMID:34648812 paracetamol multiple interactions ISO RGD:69474 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of SREBF1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SREBF1 mRNA] CTD PMID:17585979 paracetamol multiple interactions ISO RGD:69473 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of SREBF1 mRNA CTD PMID:33819548 paracetamol decreases expression ISO RGD:69473 6480464 Acetaminophen results in decreased expression of SREBF1 mRNA CTD PMID:29067470 paracetamol affects expression ISO RGD:69474 6480464 Acetaminophen affects the expression of SREBF1 mRNA CTD PMID:17562736 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of SREBF1 mRNA CTD PMID:17202758 more ... paxilline increases expression ISO RGD:69473 6480464 paxilline results in increased expression of SREBF1 mRNA CTD PMID:32123961 paxilline multiple interactions ISO RGD:69473 6480464 [Bexarotene co-treated with paxilline] results in increased expression of SREBF1 mRNA, [CD 3254 co-treated with paxilline] results in increased expression of SREBF1 mRNA CTD PMID:32123961 PD 168393 multiple interactions EXP 6480464 PD168393 inhibits the reaction [Glucose results in increased activity of and results in increased cleavage of SREBF1 protein] CTD PMID:22031849 penconazole increases expression ISO RGD:69474 6480464 penconazole results in increased expression of SREBF1 mRNA CTD PMID:31733957 perfluorobutanesulfonic acid increases expression ISO RGD:69473 6480464 perfluorobutanesulfonic acid results in increased expression of SREBF1 mRNA CTD PMID:35337807 perfluorobutyric acid increases expression ISO RGD:69473 6480464 perfluorobutyric acid results in increased expression of SREBF1 mRNA CTD PMID:35337807 perfluorodecanoic acid increases expression ISO RGD:69474 6480464 perfluorodecanoic acid results in increased expression of SREBF1 mRNA CTD PMID:36423729 perfluorodecanoic acid multiple interactions ISO RGD:69474 6480464 benzyloxycarbonyltyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone inhibits the reaction [perfluorodecanoic acid results in increased expression of SREBF1 mRNA] CTD PMID:36423729 perfluorododecanoic acid increases expression EXP 6480464 perfluorododecanoic acid results in increased expression of SREBF1 mRNA CTD PMID:23353032 perfluorododecanoic acid increases expression ISO RGD:69473 6480464 perfluorododecanoic acid results in increased expression of SREBF1 mRNA CTD PMID:35337807 perfluoroheptanoic acid increases expression ISO RGD:69473 6480464 perfluoro-n-heptanoic acid results in increased expression of SREBF1 mRNA CTD PMID:35337807 perfluorohexanoic acid increases expression ISO RGD:69473 6480464 perfluorohexanoic acid results in increased expression of SREBF1 mRNA CTD PMID:35337807 perfluorononanoic acid increases expression EXP 6480464 perfluoro-n-nonanoic acid results in increased expression of SREBF1 mRNA CTD PMID:22648072 perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of SREBF1 mRNA CTD PMID:19162173 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:69473 6480464 perfluorooctane sulfonic acid results in decreased expression of SREBF1 mRNA CTD PMID:32253466 perfluorooctane-1-sulfonic acid increases cleavage ISO RGD:69474 6480464 perfluorooctane sulfonic acid results in increased cleavage of SREBF1 protein CTD PMID:28288859 perfluorooctane-1-sulfonic acid increases expression ISO RGD:69474 6480464 perfluorooctane sulfonic acid results in increased expression of SREBF1 mRNA CTD PMID:26548598 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of SREBF1 mRNA CTD PMID:18692542 , PMID:21723365 perfluorooctanesulfonamide increases expression ISO RGD:69473 6480464 perfluorooctanesulfonamide analog results in increased expression of SREBF1 mRNA, perfluorooctanesulfonamide results in increased expression of SREBF1 mRNA CTD PMID:35337807 perfluorooctanoic acid increases expression ISO RGD:69474 6480464 perfluorooctanoic acid results in increased expression of SREBF1 mRNA CTD PMID:25092180 perfluorooctanoic acid decreases expression ISO RGD:69473 6480464 perfluorooctanoic acid results in decreased expression of SREBF1 mRNA CTD PMID:32253466 perfluorooctanoic acid multiple interactions ISO RGD:69474 6480464 [perfluorooctanoic acid co-treated with Dietary Fats] results in increased expression of SREBF1 mRNA CTD PMID:30711707 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of SREBF1 mRNA CTD PMID:21723365 perfluorooctanoic acid increases expression ISO RGD:69473 6480464 perfluorooctanoic acid results in increased expression of SREBF1 mRNA CTD PMID:21723365 perfluorooctanoic acid decreases expression ISO RGD:69474 6480464 perfluorooctanoic acid results in decreased expression of SREBF1 mRNA CTD PMID:25092180 , PMID:30657992 perfluorooctanoic acid increases cleavage ISO RGD:69474 6480464 perfluorooctanoic acid results in increased cleavage of SREBF1 protein CTD PMID:25092180 perfluoropentanoic acid increases expression ISO RGD:69473 6480464 perfluoropentanoic acid results in increased expression of SREBF1 mRNA CTD PMID:35337807 perfluoroundecanoic acid increases expression ISO RGD:69473 6480464 perfluoroundecanoic acid results in increased expression of SREBF1 mRNA CTD PMID:35337807 permethrin multiple interactions ISO RGD:69474 6480464 [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SREBF1 mRNA more ... CTD PMID:29751049 phenformin decreases expression EXP 6480464 Phenformin results in decreased expression of SREBF1 mRNA CTD PMID:31324951 phenobarbital multiple interactions ISO RGD:69474 6480464 NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of SREBF1 mRNA] CTD PMID:19482888 phenobarbital decreases expression ISO RGD:69473 6480464 Phenobarbital results in decreased expression of SREBF1 mRNA CTD PMID:21768169 phenobarbital multiple interactions ISO RGD:69473 6480464 [Progesterone co-treated with Estradiol] inhibits the reaction [Phenobarbital results in decreased expression of SREBF1 mRNA] more ... CTD PMID:21768169 phenobarbital affects expression ISO RGD:69474 6480464 Phenobarbital affects the expression of SREBF1 mRNA CTD PMID:23091169 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of SREBF1 mRNA CTD PMID:19162173 , PMID:28520973 phenobarbital decreases expression ISO RGD:69474 6480464 Phenobarbital results in decreased expression of SREBF1 mRNA CTD PMID:19482888 picolinic acid affects localization ISO RGD:69474 6480464 picolinic acid affects the localization of SREBF1 protein CTD PMID:16870493 pirinixic acid multiple interactions ISO RGD:69474 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of SREBF1 mRNA more ... CTD PMID:15777286 more ... pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of SREBF1 mRNA CTD PMID:19162173 pirinixic acid multiple interactions EXP 6480464 [[[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased localization of and results in decreased activity of SREBF1 protein] which results in decreased expression of FASN mRNA] which results in decreased abundance of Triglycerides, [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased localization of and results in decreased activity of SREBF1 protein CTD PMID:19248225 pirinixic acid increases cleavage ISO RGD:69474 6480464 pirinixic acid results in increased cleavage of SREBF1 protein CTD PMID:15777286 pirinixic acid increases expression ISO RGD:69474 6480464 pirinixic acid results in increased expression of SREBF1 mRNA CTD PMID:17426115 , PMID:18301758 platycodin D multiple interactions ISO RGD:69473 6480464 dorsomorphin inhibits the reaction [platycodin D inhibits the reaction [Glucose results in increased expression of SREBF1 mRNA]] more ... CTD PMID:23319015 pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of SREBF1 mRNA CTD PMID:19162173 pregnenolone 16alpha-carbonitrile decreases expression ISO RGD:69474 6480464 Pregnenolone Carbonitrile results in decreased expression of SREBF1 mRNA CTD PMID:28903501 pregnenolone 16alpha-carbonitrile multiple interactions ISO RGD:69474 6480464 Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of SREBF1 mRNA] CTD PMID:20359477 progesterone multiple interactions ISO RGD:69474 6480464 1 more ... CTD PMID:21768169 progesterone multiple interactions ISO RGD:69473 6480464 [Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:21768169 progesterone increases expression EXP 6480464 Progesterone results in increased expression of SREBF1 mRNA CTD PMID:20726854 propamocarb decreases expression ISO RGD:69474 6480464 propamocarb results in decreased expression of SREBF1 mRNA CTD PMID:29137890 propiconazole decreases expression ISO RGD:69474 6480464 propiconazole results in decreased expression of SREBF1 mRNA CTD PMID:21278054 propiconazole multiple interactions ISO RGD:69473 6480464 [propiconazole co-treated with tebuconazole] results in increased expression of SREBF1 mRNA CTD PMID:30989312 propiconazole decreases expression ISO RGD:69473 6480464 propiconazole results in decreased expression of SREBF1 mRNA CTD PMID:30989312 , PMID:33575850 puerarin multiple interactions ISO RGD:69474 6480464 puerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of SREBF1 mRNA] CTD PMID:31273855 Pyridostigmine bromide multiple interactions ISO RGD:69474 6480464 [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SREBF1 mRNA more ... CTD PMID:29751049 quercetin multiple interactions ISO RGD:69473 6480464 Quercetin inhibits the reaction [[Fatty Acids co-treated with INS protein] results in increased expression of SREBF1 mRNA] more ... CTD PMID:23647015 , PMID:24648896 quercetin multiple interactions ISO RGD:69474 6480464 Quercetin inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SREBF1 protein] more ... CTD PMID:18586010 more ... quercetin increases expression ISO RGD:69473 6480464 Quercetin results in increased expression of SREBF1 mRNA CTD PMID:21632981 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [Glucose results in increased expression of SREBF1 protein] more ... CTD PMID:23647015 raffinose decreases expression ISO RGD:69473 6480464 Raffinose results in decreased expression of SREBF1 mRNA CTD PMID:29458019 raffinose decreases expression ISO RGD:69474 6480464 Raffinose results in decreased expression of SREBF1 mRNA CTD PMID:29458019 raloxifene multiple interactions ISO RGD:69473 6480464 [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SREBF1 mRNA CTD PMID:19059307 reactive oxygen species affects expression ISO RGD:69473 6480464 Reactive Oxygen Species affects the expression of SREBF1 mRNA CTD PMID:25800948 resveratrol decreases expression ISO RGD:69474 6480464 [resveratrol results in decreased expression of SREBF1 mRNA] which results in decreased expression of FASN mRNA more ... CTD PMID:22659145 , PMID:23090186 resveratrol decreases expression ISO RGD:69473 6480464 Resveratrol results in decreased expression of SREBF1 mRNA CTD PMID:30776459 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of SREBF1 mRNA CTD PMID:23209300 resveratrol multiple interactions ISO RGD:69474 6480464 [Resveratrol co-treated with Dietary Fats] results in decreased expression of SREBF1 mRNA more ... CTD PMID:18755807 more ... resveratrol increases expression ISO RGD:69473 6480464 resveratrol results in increased expression of SREBF1 protein modified form CTD PMID:22153697 resveratrol multiple interactions ISO RGD:69473 6480464 [Resveratrol results in increased activity of and results in increased cleavage of [SREBF1 protein co-treated with SREBF2 protein]] which results in increased expression of LDLR mRNA more ... CTD PMID:22153697 more ... resveratrol multiple interactions EXP 6480464 [Fenofibrate co-treated with Resveratrol] inhibits the reaction [Fructose results in increased expression of SREBF1 mRNA] more ... CTD PMID:18239056 more ... risperidone multiple interactions ISO RGD:69474 6480464 Berberine inhibits the reaction [Risperidone results in increased expression of SREBF1 mRNA], Berberine inhibits the reaction [Risperidone results in increased expression of SREBF1 protein] CTD PMID:20564506 risperidone increases expression ISO RGD:69474 6480464 Risperidone results in increased expression of SREBF1 mRNA, Risperidone results in increased expression of SREBF1 protein CTD PMID:20564506 ritonavir multiple interactions ISO RGD:69474 6480464 Ritonavir promotes the reaction [[INS1 protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of SREBF1 protein] CTD PMID:11101056 rotenone increases expression ISO RGD:69473 6480464 Rotenone results in increased expression of SREBF1 mRNA CTD PMID:17651460 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of SREBF1 mRNA CTD PMID:19693701 , PMID:28374803 S-allylcysteine decreases expression ISO RGD:69473 6480464 S-allylcysteine results in decreased expression of SREBF1 protein CTD PMID:23465592 S-allylcysteine multiple interactions ISO RGD:69473 6480464 dorsomorphin inhibits the reaction [S-allylcysteine results in decreased expression of SREBF1 protein] more ... CTD PMID:23465592 S-butyl-DL-homocysteine (S,R)-sulfoximine decreases expression EXP 6480464 Buthionine Sulfoximine results in decreased expression of SREBF1 mRNA CTD PMID:20482862 salubrinal multiple interactions EXP 6480464 salubrinal inhibits the reaction [AGT protein promotes the reaction [SREBF1 protein binds to TGFB1 promoter]] more ... CTD PMID:25398788 SB 431542 multiple interactions ISO RGD:69473 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SREBF1 mRNA CTD PMID:27188386 scopoletin multiple interactions EXP 6480464 Scopoletin inhibits the reaction [Ethanol results in increased expression of SREBF1 mRNA] CTD PMID:26115886 selenium atom increases expression EXP 6480464 Selenium results in increased expression of SREBF1 mRNA CTD PMID:19022953 selenium atom multiple interactions ISO RGD:69474 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA] CTD PMID:36464106 selenium atom multiple interactions EXP 6480464 [[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:30031400 selenium atom increases expression ISO RGD:69474 6480464 Selenium results in increased expression of SREBF1 mRNA CTD PMID:28810182 selenomethionine increases expression ISO RGD:69474 6480464 Selenomethionine results in increased expression of SREBF1 mRNA CTD PMID:28810182 selenomethionine decreases methylation ISO RGD:69474 6480464 Selenomethionine results in decreased methylation of SREBF1 exon CTD PMID:28810182 senecionine decreases expression ISO RGD:69474 6480464 senecionine results in decreased expression of SREBF1 protein CTD PMID:35357534 silibinin decreases response to substance ISO RGD:69473 6480464 SREBF1 protein results in decreased susceptibility to Silybin CTD PMID:25294820 silibinin multiple interactions ISO RGD:69473 6480464 fatostatin promotes the reaction [Silybin results in decreased cleavage of SREBF1 protein], Silybin results in decreased cleavage of and results in increased phosphorylation of SREBF1 protein CTD PMID:25294820 simvastatin decreases expression EXP 6480464 Simvastatin results in decreased expression of SREBF1 mRNA CTD PMID:25055962 simvastatin increases localization ISO RGD:69473 6480464 Simvastatin results in increased localization of SREBF1 protein CTD PMID:17655842 sirolimus decreases expression ISO RGD:69474 6480464 Sirolimus results in decreased expression of SREBF1 mRNA CTD PMID:15358118 sirtinol multiple interactions ISO RGD:69473 6480464 sirtinol inhibits the reaction [S-allylcysteine results in decreased expression of SREBF1 protein] CTD PMID:23465592 sodium arsenite decreases expression ISO RGD:69474 6480464 sodium arsenite results in decreased expression of SREBF1 mRNA CTD PMID:23221991 more ... sodium arsenite multiple interactions ISO RGD:69474 6480464 [Palmitic Acid co-treated with sodium arsenite] results in decreased expression of SREBF1 mRNA, [sodium arsenite co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of SREBF1 mRNA CTD PMID:34968464 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of SREBF1 mRNA CTD PMID:32593899 sodium arsenite affects expression ISO RGD:69473 6480464 sodium arsenite affects the expression of SREBF1 protein CTD PMID:27932253 sodium cholate multiple interactions ISO RGD:69474 6480464 [Cholesterol more ... CTD PMID:27394961 sodium dichromate affects expression EXP 6480464 sodium bichromate affects the expression of SREBF1 mRNA CTD PMID:22110744 Sodium oleate multiple interactions ISO RGD:69474 6480464 [osteum co-treated with Palmitic Acid] results in increased expression of SREBF1 protein, decabromobiphenyl ether promotes the reaction [[osteum co-treated with Palmitic Acid] results in increased expression of SREBF1 protein] CTD PMID:34757160 starch multiple interactions EXP 6480464 Starch analog inhibits the reaction [Rapeseed Oil metabolite results in increased expression of SREBF1 mRNA] CTD PMID:27363782 stavudine multiple interactions EXP 6480464 Carnitine inhibits the reaction [Stavudine results in increased expression of SREBF1 mRNA] CTD PMID:18299183 stavudine increases expression EXP 6480464 Stavudine results in increased expression of SREBF1 mRNA CTD PMID:18299183 streptozocin multiple interactions EXP 6480464 [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of SREBF1 mRNA more ... CTD PMID:23647015 more ... streptozocin multiple interactions ISO RGD:69474 6480464 [Dietary Fats co-treated with Streptozocin] results in decreased expression of SREBF1 mRNA more ... CTD PMID:29420703 more ... streptozocin increases expression ISO RGD:69474 6480464 Streptozocin results in increased expression of SREBF1 mRNA, Streptozocin results in increased expression of SREBF1 protein CTD PMID:22031849 more ... streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of SREBF1 protein CTD PMID:28822685 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of SREBF1 mRNA, Streptozocin results in increased expression of SREBF1 protein CTD PMID:23647015 sucrose multiple interactions ISO RGD:69474 6480464 [lard co-treated with Cholesterol co-treated with Sucrose co-treated with Atrazine] results in increased expression of SREBF1 mRNA, [lard co-treated with Cholesterol co-treated with Sucrose co-treated with Ethinyl Estradiol] results in increased expression of SREBF1 mRNA CTD PMID:24440342 sucrose multiple interactions EXP 6480464 [Dietary Fats co-treated with Sucrose] results in increased expression of SREBF1 mRNA more ... CTD PMID:31175915 sulfluramid increases expression ISO RGD:69473 6480464 sulfluramid results in increased expression of SREBF1 mRNA CTD PMID:35337807 sulforaphane multiple interactions EXP 6480464 [sulforaphane co-treated with Aflatoxin B1] affects the expression of SREBF1 mRNA CTD PMID:25450479 sulforaphane decreases expression ISO RGD:69473 6480464 sulforaphane results in decreased expression of SREBF1 mRNA CTD PMID:31838189 , PMID:34767876 sulforaphane multiple interactions ISO RGD:69473 6480464 sulforaphane promotes the reaction [NFE2L2 protein results in increased expression of SREBF1 mRNA] CTD PMID:28796629 sunitinib increases expression ISO RGD:69473 6480464 Sunitinib results in increased expression of SREBF1 mRNA CTD PMID:31533062 tamoxifen multiple interactions ISO RGD:69473 6480464 [Tamoxifen co-treated with ESR2 protein] results in decreased expression of SREBF1 mRNA CTD PMID:19059307 tartrazine multiple interactions ISO RGD:69473 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of SREBF1 mRNA CTD PMID:33819548 tauroursodeoxycholic acid multiple interactions EXP 6480464 ursodoxicoltaurine inhibits the reaction [AGT protein promotes the reaction [SREBF1 protein binds to TGFB1 promoter]] CTD PMID:25398788 tebuconazole multiple interactions ISO RGD:69473 6480464 [propiconazole co-treated with tebuconazole] results in increased expression of SREBF1 mRNA CTD PMID:30989312 tebuconazole increases expression ISO RGD:69473 6480464 tebuconazole results in increased expression of SREBF1 mRNA CTD PMID:30989312 tectorigenin multiple interactions ISO RGD:69474 6480464 tectorigenin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA], tectorigenin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 protein] CTD PMID:35390440 testosterone increases expression ISO RGD:69474 6480464 Testosterone results in increased expression of SREBF1 mRNA CTD PMID:16579987 testosterone cypionate increases expression ISO RGD:69474 6480464 testosterone 17 beta-cypionate results in increased expression of SREBF1 mRNA CTD PMID:29704577 testosterone cypionate multiple interactions ISO RGD:69474 6480464 [testosterone 17 beta-cypionate co-treated with Dietary Fats] results in increased expression of SREBF1 mRNA CTD PMID:29704577 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of SREBF1 mRNA CTD PMID:17202758 more ... tetrachloromethane decreases expression ISO RGD:69474 6480464 Carbon Tetrachloride results in decreased expression of SREBF1 mRNA CTD PMID:27339419 , PMID:31919559 tetracycline increases expression ISO RGD:69474 6480464 Tetracycline results in increased expression of SREBF1 mRNA CTD PMID:16917069 tetracycline increases expression ISO RGD:69473 6480464 Tetracycline results in increased expression of SREBF1 mRNA CTD PMID:27089845 tetracycline decreases expression EXP 6480464 Tetracycline results in decreased expression of SREBF1 mRNA CTD PMID:17202758 more ... tetramethylpyrazine multiple interactions ISO RGD:69474 6480464 NFE2L2 affects the reaction [tetramethylpyrazine inhibits the reaction [Ethanol results in increased expression of SREBF1 mRNA]] more ... CTD PMID:27837167 thapsigargin multiple interactions ISO RGD:69473 6480464 Thapsigargin promotes the reaction [HNRNPA1 protein binds to SREBF1 5' UTR] CTD PMID:23106379 thapsigargin multiple interactions EXP 6480464 Thapsigargin promotes the reaction [SREBF1 protein binds to TGFB1 promoter] CTD PMID:25398788 thapsigargin increases cleavage EXP 6480464 Thapsigargin results in increased cleavage of SREBF1 protein CTD PMID:25398788 theophylline decreases expression EXP 6480464 Theophylline results in decreased expression of SREBF1 mRNA CTD PMID:17522070 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of SREBF1 mRNA CTD PMID:23411599 , PMID:34492290 thymol multiple interactions ISO RGD:69474 6480464 Thymol inhibits the reaction [Dietary Fats results in increased expression of SREBF1 protein] CTD PMID:26680107 thymol sulfate(1-) multiple interactions ISO RGD:69474 6480464 Thymol inhibits the reaction [Dietary Fats results in increased expression of SREBF1 protein] CTD PMID:26680107 tianeptine increases expression ISO RGD:69473 6480464 tianeptine results in increased expression of SREBF1 mRNA CTD PMID:27089845 topiramate increases expression EXP 6480464 topiramate results in increased expression of SREBF1 mRNA CTD PMID:16979414 trametinib multiple interactions ISO RGD:69473 6480464 trametinib affects the reaction [[BRAF protein affects the susceptibility to Vemurafenib] which affects the cleavage of SREBF1 protein] CTD PMID:29950559 trans-caffeic acid multiple interactions ISO RGD:69473 6480464 [Metformin co-treated with caffeic acid] results in decreased expression of SREBF1 protein CTD PMID:28576465 tributyl phosphate increases expression ISO RGD:69473 6480464 tributyl phosphate results in increased expression of SREBF1 mRNA CTD PMID:30966736 tributylstannane multiple interactions ISO RGD:69473 6480464 tributyltin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA] CTD PMID:25932594 tributylstannane increases expression ISO RGD:69473 6480464 tributyltin results in increased expression of SREBF1 mRNA CTD PMID:28011154 tributylstannane increases expression ISO RGD:69474 6480464 tributyltin results in increased expression of SREBF1 mRNA CTD PMID:23322813 , PMID:25932594 Tributyltin oxide increases expression ISO RGD:69474 6480464 bis(tri-n-butyltin)oxide results in increased expression of SREBF1 mRNA CTD PMID:25270620 Tributyltin oxide increases expression EXP 6480464 bis(tri-n-butyltin)oxide results in increased expression of SREBF1 mRNA CTD PMID:17553608 triclosan affects expression ISO RGD:69473 6480464 Triclosan affects the expression of SREBF1 mRNA CTD PMID:31714634 triolein multiple interactions ISO RGD:69474 6480464 Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 mRNA]], Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 protein]] CTD PMID:15066988 triphenyl phosphate increases expression ISO RGD:69473 6480464 triphenyl phosphate results in increased expression of SREBF1 mRNA CTD PMID:28934090 , PMID:30966736 triphenyl phosphate increases expression ISO RGD:69474 6480464 triphenyl phosphate results in increased expression of SREBF1 mRNA CTD PMID:36563926 triphenylstannane multiple interactions ISO RGD:69473 6480464 [triphenyltin chloride results in increased abundance of triphenyltin] which results in increased expression of SREBF1 mRNA CTD PMID:35998708 tris(2-butoxyethyl) phosphate increases expression ISO RGD:69473 6480464 tris(2-butoxyethyl) phosphate results in increased expression of SREBF1 mRNA CTD PMID:30966736 tris(2-chloroethyl) phosphate increases expression ISO RGD:69474 6480464 tris(chloroethyl)phosphate results in increased expression of SREBF1 mRNA, tris(chloroethyl)phosphate results in increased expression of SREBF1 protein CTD PMID:35780845 tris(2-chloroethyl) phosphate multiple interactions ISO RGD:69474 6480464 Chenodeoxycholic Acid inhibits the reaction [tris(chloroethyl)phosphate results in increased expression of SREBF1 mRNA], Chenodeoxycholic Acid inhibits the reaction [tris(chloroethyl)phosphate results in increased expression of SREBF1 protein] CTD PMID:35780845 Tris(2-ethylhexyl) phosphate increases expression ISO RGD:69473 6480464 tris(2-ethylhexyl)phosphate results in increased expression of SREBF1 mRNA CTD PMID:30966736 troglitazone multiple interactions EXP 6480464 [[[troglitazone binds to and results in increased activity of PPARG protein] which results in decreased localization of and results in decreased activity of SREBF1 protein] which results in decreased expression of FASN mRNA] which results in decreased abundance of Triglycerides, [troglitazone binds to and results in increased activity of PPARG protein] which results in decreased localization of and results in decreased activity of SREBF1 protein CTD PMID:19248225 troglitazone multiple interactions ISO RGD:69473 6480464 [1-Methyl-3-isobutylxanthine co-treated with troglitazone co-treated with INS protein] results in increased expression of SREBF1 mRNA CTD PMID:27003841 troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of SREBF1 mRNA CTD PMID:10900012 troglitazone decreases expression ISO RGD:69473 6480464 troglitazone results in decreased expression of SREBF1 mRNA CTD PMID:19140230 trovafloxacin decreases expression EXP 6480464 trovafloxacin results in decreased expression of SREBF1 mRNA CTD PMID:24136188 tunicamycin increases cleavage ISO RGD:69474 6480464 Tunicamycin results in increased cleavage of SREBF1 protein CTD PMID:22414386 tunicamycin multiple interactions ISO RGD:69474 6480464 Luteolin inhibits the reaction [Tunicamycin results in increased expression of SREBF1 mRNA] CTD PMID:32407927 tunicamycin increases expression ISO RGD:69474 6480464 Tunicamycin results in increased expression of SREBF1 mRNA CTD PMID:32407927 tunicamycin increases cleavage EXP 6480464 Tunicamycin results in increased cleavage of SREBF1 protein CTD PMID:25398788 tunicamycin increases expression EXP 6480464 Tunicamycin results in increased expression of SREBF1 protein CTD PMID:23106379 tunicamycin multiple interactions ISO RGD:69473 6480464 HNRNPA1 mutant form inhibits the reaction [Tunicamycin results in increased expression of SREBF1 protein], Tunicamycin promotes the reaction [HNRNPA1 protein binds to SREBF1 5' UTR] CTD PMID:23106379 tunicamycin multiple interactions EXP 6480464 HNRNPA1 mutant form inhibits the reaction [Tunicamycin results in increased expression of SREBF1 protein], Tunicamycin promotes the reaction [SREBF1 protein binds to TGFB1 promoter] CTD PMID:23106379 , PMID:25398788 tunicamycin increases expression ISO RGD:69473 6480464 Tunicamycin results in increased expression of SREBF1 protein CTD PMID:23106379 tyrphostin AG 1478 multiple interactions EXP 6480464 RTKI cpd inhibits the reaction [Glucose results in increased activity of and results in increased cleavage of SREBF1 protein] CTD PMID:22031849 valdecoxib decreases expression EXP 6480464 valdecoxib results in decreased expression of SREBF1 mRNA CTD PMID:24136188 valproic acid affects expression ISO RGD:69474 6480464 Valproic Acid affects the expression of SREBF1 mRNA CTD PMID:17292431 , PMID:17963808 valproic acid multiple interactions ISO RGD:69473 6480464 NR1H3 protein affects the reaction [Valproic Acid results in increased expression of SREBF1 mRNA], NR1H3 protein promotes the reaction [Valproic Acid results in increased expression of SREBF1 mRNA] CTD PMID:30003287 valproic acid decreases expression ISO RGD:69473 6480464 Valproic Acid results in decreased expression of SREBF1 mRNA CTD PMID:29154799 valproic acid affects expression ISO RGD:69473 6480464 Valproic Acid affects the expression of SREBF1 mRNA CTD PMID:25979313 valproic acid increases expression ISO RGD:69473 6480464 Valproic Acid results in increased expression of SREBF1 mRNA, Valproic Acid results in increased expression of SREBF1 protein CTD PMID:25716160 more ... vancomycin multiple interactions ISO RGD:69474 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA], [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA CTD PMID:36464106 vemurafenib decreases cleavage ISO RGD:69473 6480464 Vemurafenib results in decreased cleavage of SREBF1 protein CTD PMID:29950559 vemurafenib multiple interactions ISO RGD:69473 6480464 [BRAF protein affects the susceptibility to Vemurafenib] which affects the cleavage of SREBF1 protein more ... CTD PMID:29950559 vemurafenib decreases expression ISO RGD:69473 6480464 Vemurafenib results in decreased expression of SREBF1 mRNA alternative form CTD PMID:29950559 vincristine decreases expression ISO RGD:69473 6480464 Vincristine results in decreased expression of SREBF1 mRNA CTD PMID:23649840 vitamin D multiple interactions ISO RGD:69473 6480464 [Vitamin D co-treated with bisphenol A co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] affects the expression of SREBF1 mRNA CTD PMID:33836827 withaferin A multiple interactions ISO RGD:69474 6480464 withaferin A inhibits the reaction [Ethanol results in increased expression of SREBF1 mRNA] CTD PMID:34995708 wortmannin multiple interactions EXP 6480464 Wortmannin inhibits the reaction [AGT protein results in increased cleavage of SREBF1 protein], Wortmannin inhibits the reaction [Glucose results in increased cleavage of SREBF1 protein] CTD PMID:22031849 , PMID:25398788 xylose increases expression ISO RGD:69474 6480464 Xylose results in increased expression of SREBF1 mRNA CTD PMID:10913129 Y-27632 multiple interactions EXP 6480464 Y 27632 inhibits the reaction [Glucose results in increased cleavage of SREBF1 protein] CTD PMID:22031849
