Gene: Slit1 (slit guidance ligand 1) Rattus norvegicus
Symbol: Slit1
Name: slit guidance ligand 1
Description: ENCODES a protein that exhibits heparan sulfate proteoglycan binding; Roundabout binding (ortholog); INVOLVED IN brain development; negative regulation of axon extension involved in axon guidance; spinal cord development; ASSOCIATED WITH Brain Injuries; Spinal Cord Injuries (ortholog); FOUND IN extracellular space; INTERACTS WITH 17alpha-ethynylestradiol; 3H-1,2-dithiole-3-thione; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MEGF4; multiple EGF-like domains protein 4; multiple epidermal growth factor-like domains 4; multiple epidermal growth factor-like domains protein 4; slit (Drosophila) homolog 1; slit homolog 1 (Drosophila); slit homolog 1 protein; slit-1
Homo sapiens (human) : SLIT1 (slit guidance ligand 1)  HGNC  AGR
Mus musculus (house mouse) : Slit1 (slit guidance ligand 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Slit1 (slit guidance ligand 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLIT1 (slit guidance ligand 1)
Canis lupus familiaris (dog) : SLIT1 (slit guidance ligand 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slit1 (slit guidance ligand 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01260,843,481 - 260,992,366 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01268,298,678 - 268,445,090 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41246,813,909 - 246,964,408 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11246,928,385 - 247,078,883 (-)NCBI
Celera1236,249,200 - 236,395,640 (-)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Slit1
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69307
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE