Pdcd6ip (programmed cell death 6 interacting protein) - Rat Genome Database

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Gene: Pdcd6ip (programmed cell death 6 interacting protein) Rattus norvegicus
Analyze
Symbol: Pdcd6ip
Name: programmed cell death 6 interacting protein
RGD ID: 68357
Description: Enables SH3 domain binding activity. Predicted to be involved in several processes, including bicellular tight junction assembly; cytokinetic process; and positive regulation of cellular component biogenesis. Predicted to be located in several cellular components, including Flemming body; endoplasmic reticulum exit site; and immunological synapse. Predicted to be active in endosome. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Orthologous to human PDCD6IP (programmed cell death 6 interacting protein); PARTICIPATES IN endocytosis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AIP1; ALG-2 interacting protein 1; ALG-2 interacting protein X; ALG-2-interacting protein 1; Alix; programmed cell death 6-interacting protein; RGD1561176
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88122,469,223 - 122,524,993 (-)NCBIGRCr8
mRatBN7.28113,590,998 - 113,646,795 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8113,590,998 - 113,646,773 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8119,207,150 - 119,262,921 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08117,406,414 - 117,462,188 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08115,249,172 - 115,304,948 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08121,916,233 - 121,973,145 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8121,916,185 - 121,973,125 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08121,231,793 - 121,287,105 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48118,314,910 - 118,350,134 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera8112,840,809 - 112,895,775 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1,4-dithiothreitol  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
antimycin A  (ISO)
aristolochic acid A  (ISO)
atrazine  (ISO)
azoxystrobin  (ISO)
beauvericin  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
butyric acid  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
Cuprizon  (EXP)
dexamethasone  (ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (ISO)
dioxygen  (ISO)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
fenthion  (ISO)
flavonoids  (EXP)
flutamide  (EXP)
folic acid  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
hesperetin  (ISO)
Honokiol  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
L-1,4-dithiothreitol  (ISO)
methapyrilene  (EXP)
methylmercury chloride  (ISO)
morusin  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
nitric oxide  (ISO)
oxybenzone  (EXP)
ozone  (ISO)
paracetamol  (ISO)
phenobarbital  (ISO)
picoxystrobin  (ISO)
poly(I:C)  (EXP)
pyrene  (EXP)
rac-lactic acid  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
sodium dichromate  (EXP)
succimer  (ISO)
thapsigargin  (ISO)
titanium dioxide  (ISO)
trichloroethene  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
uranium atom  (ISO)
vinclozolin  (EXP)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The glioma-associated protein SETA interacts with AIP1/Alix and ALG-2 and modulates apoptosis in astrocytes. Chen B, etal., J Biol Chem 2000 Jun 23;275(25):19275-81.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:8889548   PMID:9880530   PMID:10200558   PMID:12771190   PMID:14505570   PMID:14519844   PMID:15086793   PMID:15326289   PMID:15557335   PMID:16501490   PMID:16957052   PMID:17634366  
PMID:18641129   PMID:19056867   PMID:19199708   PMID:19520058   PMID:19523902   PMID:19706535   PMID:19946888   PMID:20616062   PMID:21276792   PMID:21423176   PMID:22547407   PMID:22660413  
PMID:22871113   PMID:23092844   PMID:23376485   PMID:23523921   PMID:23533145   PMID:23924735   PMID:24105262   PMID:24107264   PMID:24769233   PMID:27336173   PMID:31077357  


Genomics

Comparative Map Data
Pdcd6ip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88122,469,223 - 122,524,993 (-)NCBIGRCr8
mRatBN7.28113,590,998 - 113,646,795 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8113,590,998 - 113,646,773 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8119,207,150 - 119,262,921 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08117,406,414 - 117,462,188 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08115,249,172 - 115,304,948 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08121,916,233 - 121,973,145 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8121,916,185 - 121,973,125 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08121,231,793 - 121,287,105 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48118,314,910 - 118,350,134 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera8112,840,809 - 112,895,775 (-)NCBICelera
Cytogenetic Map8q32NCBI
PDCD6IP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38333,798,630 - 33,869,703 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl333,798,571 - 33,869,707 (+)EnsemblGRCh38hg38GRCh38
GRCh37333,840,122 - 33,911,195 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36333,814,561 - 33,886,198 (+)NCBINCBI36Build 36hg18NCBI36
Build 34333,814,560 - 33,886,198NCBI
Celera333,783,127 - 33,854,073 (+)NCBICelera
Cytogenetic Map3p22.3NCBI
HuRef333,781,264 - 33,852,387 (+)NCBIHuRef
CHM1_1333,789,988 - 33,861,201 (+)NCBICHM1_1
T2T-CHM13v2.0333,799,362 - 33,870,437 (+)NCBIT2T-CHM13v2.0
Pdcd6ip
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399113,480,812 - 113,537,457 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9113,480,812 - 113,537,327 (-)EnsemblGRCm39 Ensembl
GRCm389113,651,744 - 113,708,279 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9113,651,744 - 113,708,259 (-)EnsemblGRCm38mm10GRCm38
MGSCv379113,560,862 - 113,617,377 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369113,503,631 - 113,556,805 (-)NCBIMGSCv36mm8
Celera9113,360,961 - 113,417,417 (-)NCBICelera
Cytogenetic Map9F3NCBI
cM Map964.03NCBI
Pdcd6ip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554211,034,843 - 1,110,438 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554211,034,843 - 1,109,637 (+)NCBIChiLan1.0ChiLan1.0
PDCD6IP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2233,773,923 - 33,847,614 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1333,778,883 - 33,852,381 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0333,719,603 - 33,793,301 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1334,016,152 - 34,093,631 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl334,016,474 - 34,093,631 (+)Ensemblpanpan1.1panPan2
PDCD6IP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1234,112,299 - 4,199,230 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl234,112,363 - 4,196,342 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha234,154,337 - 4,240,985 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0234,374,570 - 4,462,420 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1234,207,505 - 4,294,589 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0234,339,176 - 4,426,011 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0234,308,530 - 4,395,465 (+)NCBIUU_Cfam_GSD_1.0
Pdcd6ip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118190,870,278 - 190,948,263 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647324,010,935 - 24,086,846 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647324,010,942 - 24,086,836 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDCD6IP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1319,597,059 - 19,665,996 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11319,597,064 - 19,664,047 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21321,193,109 - 21,243,506 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PDCD6IP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11578,265,099 - 78,339,307 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1578,265,252 - 78,339,873 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604151,646,595 - 51,721,427 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pdcd6ip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478811,772,396 - 11,845,765 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478811,772,268 - 11,849,040 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pdcd6ip
290 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:383
Count of miRNA genes:227
Interacting mature miRNAs:288
Transcripts:ENSRNOT00000012114
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8100149864120994388Rat
1599689Iddm24Insulin dependent diabetes mellitus QTL 244.720.001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)8112834440118649220Rat

Markers in Region
RH127559  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28113,593,711 - 113,593,931 (+)MAPPERmRatBN7.2
Rnor_6.08121,918,947 - 121,919,166NCBIRnor6.0
Rnor_5.08121,234,507 - 121,234,726UniSTSRnor5.0
Celera8112,843,523 - 112,843,742UniSTS
RH 3.4 Map81197.1UniSTS
Cytogenetic Map8q32UniSTS
C76364  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28113,593,843 - 113,594,060 (+)MAPPERmRatBN7.2
Rnor_6.08121,919,079 - 121,919,295NCBIRnor6.0
Rnor_5.08121,234,639 - 121,234,855UniSTSRnor5.0
Celera8112,843,655 - 112,843,871UniSTS
Cytogenetic Map8q32UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000012114   ⟹   ENSRNOP00000012114
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8113,590,998 - 113,646,773 (-)Ensembl
Rnor_6.0 Ensembl8121,916,185 - 121,973,125 (-)Ensembl
RefSeq Acc Id: NM_001029910   ⟹   NP_001025081
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88122,469,223 - 122,524,993 (-)NCBI
mRatBN7.28113,590,998 - 113,646,773 (-)NCBI
Rnor_6.08121,916,233 - 121,973,145 (-)NCBI
Rnor_5.08121,231,793 - 121,287,105 (-)NCBI
RGSC_v3.48118,314,910 - 118,350,134 (-)RGD
Celera8112,840,809 - 112,895,775 (-)RGD
Sequence:
RefSeq Acc Id: XM_006243997   ⟹   XP_006244059
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88122,469,223 - 122,524,861 (-)NCBI
mRatBN7.28113,590,998 - 113,646,795 (-)NCBI
Rnor_6.08121,916,233 - 121,973,140 (-)NCBI
Rnor_5.08121,231,793 - 121,287,105 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001025081 (Get FASTA)   NCBI Sequence Viewer  
  XP_006244059 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF07179 (Get FASTA)   NCBI Sequence Viewer  
  EDL77006 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012114
  ENSRNOP00000012114.8
  ENSRNOP00055008843
  ENSRNOP00060028401
  ENSRNOP00065004142
GenBank Protein Q9QZA2 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001025081   ⟸   NM_001029910
- UniProtKB: A0A140TAA4 (UniProtKB/TrEMBL),   A6I3M1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244059   ⟸   XM_006243997
- Peptide Label: isoform X1
- UniProtKB: Q9QZA2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000012114   ⟸   ENSRNOT00000012114
Protein Domains
BRO1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QZA2-F1-model_v2 AlphaFold Q9QZA2 1-873 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696348
Promoter ID:EPDNEW_R6872
Type:initiation region
Name:Pdcd6ip_1
Description:programmed cell death 6 interacting protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08121,973,122 - 121,973,182EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:68357 AgrOrtholog
BioCyc Gene G2FUF-28947 BioCyc
Ensembl Genes ENSRNOG00000008981 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055006856 UniProtKB/Swiss-Prot
  ENSRNOG00060019992 UniProtKB/Swiss-Prot
  ENSRNOG00065003928 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000012114 UniProtKB/TrEMBL
  ENSRNOT00000012114.8 UniProtKB/Swiss-Prot
  ENSRNOT00055011272 UniProtKB/Swiss-Prot
  ENSRNOT00060034585 UniProtKB/Swiss-Prot
  ENSRNOT00065005744 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.280 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  alix/aip1 in complex with the ypdl late domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  alix/aip1 like domains UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ALIX_V_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BRO1-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BRO1_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BRO1_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:501083 UniProtKB/TrEMBL
NCBI Gene Pdcd6ip ENTREZGENE
PANTHER PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR23030 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ALIX_LYPXL_bnd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BRO1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pdcd6ip PhenoGen
PROSITE BRO1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008981 RatGTEx
  ENSRNOG00055006856 RatGTEx
  ENSRNOG00060019992 RatGTEx
  ENSRNOG00065003928 RatGTEx
SMART BRO1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC229010
UniProt A0A140TAA4 ENTREZGENE, UniProtKB/TrEMBL
  A6I3M1 ENTREZGENE, UniProtKB/TrEMBL
  PDC6I_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Pdcd6ip  programmed cell death 6 interacting protein      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference