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Gene: Pdia6 (protein disulfide isomerase family A, member 6) Rattus norvegicus
Symbol: Pdia6
Name: protein disulfide isomerase family A, member 6
RGD ID: 628688
Description: Predicted to have enzyme inhibitor activity; peptide disulfide oxidoreductase activity; and protein disulfide isomerase activity. Predicted to be involved in negative regulation of IRE1-mediated unfolded protein response and platelet aggregation. Localizes to endoplasmic reticulum lumen and smooth endoplasmic reticulum. Orthologous to human PDIA6 (protein disulfide isomerase family A member 6); PARTICIPATES IN codeine and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; etoposide pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
Also known as: CaBP1; calcium-binding protein 1; P5; protein disulfide isomerase A6; protein disulfide isomerase associated 6; protein disulfide isomerase P5; protein disulfide isomerase-related protein; protein disulfide-isomerase A6; thioredoxin domain containing 7; thioredoxin domain-containing protein 7; Txndc7
Homo sapiens (human) : PDIA6 (protein disulfide isomerase family A member 6)  HGNC  Alliance
Mus musculus (house mouse) : Pdia6 (protein disulfide isomerase associated 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdia6 (protein disulfide isomerase family A member 6)
Pan paniscus (bonobo/pygmy chimpanzee) : PDIA6 (protein disulfide isomerase family A member 6)
Canis lupus familiaris (dog) : PDIA6 (protein disulfide isomerase family A member 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdia6 (protein disulfide isomerase family A member 6)
Sus scrofa (pig) : PDIA6 (protein disulfide isomerase family A member 6)
Chlorocebus sabaeus (African green monkey) : PDIA6 (protein disulfide isomerase family A member 6)
Heterocephalus glaber (naked mole-rat) : Pdia6 (protein disulfide isomerase family A member 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0642,568,269 - 42,585,654 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl642,568,220 - 42,585,652 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0652,289,504 - 52,306,889 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera639,364,155 - 39,381,355 (+)NCBICelera
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Pdia6
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 628688
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.