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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Chemical and Drug Induced Liver Injury | | ISO | RGD:1350405 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:25231249 | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Chemical and Drug Induced Liver Injury | | ISO | RGD:1350405 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:25231249 | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | A novel mammalian lithium-sensitive enzyme with a dual enzymatic activity, 3'-phosphoadenosine 5'-phosphate phosphatase and inositol-polyphosphate 1-phosphatase. | Lopez-Coronado JM, etal., J Biol Chem 1999 Jun 4;274(23):16034-9. |
3. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
4. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
5. | Crystal structure of an enzyme displaying both inositol-polyphosphate-1-phosphatase and 3'-phosphoadenosine-5'-phosphate phosphatase activities: a novel target of lithium therapy. | Patel S, etal., J Mol Biol 2002 Jan 25;315(4):677-85. |
6. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
7. | SMPDB Annotation Import Pipeline | Pipeline to import SMPDB annotations from SMPDB into RGD |
8. | GOA pipeline | RGD automated data pipeline |
9. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
10. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
11. | Comprehensive gene review and curation | RGD comprehensive gene curation |
Bpnt1 (Rattus norvegicus - Norway rat) |
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BPNT1 (Homo sapiens - human) |
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Bpnt1 (Mus musculus - house mouse) |
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Bpnt1 (Chinchilla lanigera - long-tailed chinchilla) |
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BPNT1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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BPNT1 (Canis lupus familiaris - dog) |
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Bpnt1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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BPNT1 (Sus scrofa - pig) |
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BPNT1 (Chlorocebus sabaeus - green monkey) |
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Bpnt1 (Heterocephalus glaber - naked mole-rat) |
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Variants in Bpnt1
124 total Variants ![]() |
The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
RH129031 |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 43 | 57 | 41 | 19 | 41 | 8 | 10 | 74 | 35 | 41 | 11 | 8 |
Low | 1 | ||||||||||||
Below cutoff |
RefSeq Transcripts | NM_171990 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006250429 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006250430 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006250431 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039091064 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AJ000347 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
BC085692 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH473985 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ214355 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JACYVU010000245 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000003249 ⟹ ENSRNOP00000003249 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000088921 ⟹ ENSRNOP00000071594 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000096481 ⟹ ENSRNOP00000080410 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_171990 ⟹ NP_741987 | ||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006250429 ⟹ XP_006250491 | ||||||||||||||||
RefSeq Status: | |||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006250430 ⟹ XP_006250492 | ||||||||||||||||
RefSeq Status: | |||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006250431 ⟹ XP_006250493 | ||||||||||||||||
RefSeq Status: | |||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039091064 ⟹ XP_038946992 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_741987 | (Get FASTA) | NCBI Sequence Viewer |
XP_006250491 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006250492 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006250493 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038946992 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAH85692 | (Get FASTA) | NCBI Sequence Viewer |
CAA04022 | (Get FASTA) | NCBI Sequence Viewer | |
EDL94912 | (Get FASTA) | NCBI Sequence Viewer | |
EDL94913 | (Get FASTA) | NCBI Sequence Viewer | |
EDL94914 | (Get FASTA) | NCBI Sequence Viewer | |
EDL94915 | (Get FASTA) | NCBI Sequence Viewer | |
EDL94916 | (Get FASTA) | NCBI Sequence Viewer | |
EDL94917 | (Get FASTA) | NCBI Sequence Viewer | |
EDL94918 | (Get FASTA) | NCBI Sequence Viewer | |
EDL94919 | (Get FASTA) | NCBI Sequence Viewer | |
Q9Z1N4 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_741987 ⟸ NM_171990 |
- UniProtKB: | Q9Z1N4 (UniProtKB/Swiss-Prot) |
- Sequence: |
RefSeq Acc Id: | XP_006250491 ⟸ XM_006250429 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A0A0G2K0V3 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006250492 ⟸ XM_006250430 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A0A0G2K0V3 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006250493 ⟸ XM_006250431 |
- Peptide Label: | isoform X2 |
- UniProtKB: | Q9Z1N4 (UniProtKB/Swiss-Prot) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000071594 ⟸ ENSRNOT00000088921 |
RefSeq Acc Id: | ENSRNOP00000003249 ⟸ ENSRNOT00000003249 |
RefSeq Acc Id: | XP_038946992 ⟸ XM_039091064 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A0A0G2K0V3 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | ENSRNOP00000080410 ⟸ ENSRNOT00000096481 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q9Z1N4-F1-model_v2 | AlphaFold | Q9Z1N4 | 1-308 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13699095 | ||||||||
Promoter ID: | EPDNEW_R9616 | ||||||||
Type: | initiation region | ||||||||
Name: | Bpnt1_1 | ||||||||
Description: | 3'(2'), 5'-bisphosphate nucleotidase 1 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:621833 | AgrOrtholog |
BioCyc Gene | G2FUF-16980 | BioCyc |
Ensembl Genes | ENSRNOG00000002378 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Protein | ENSRNOP00000003249.6 | UniProtKB/TrEMBL |
ENSRNOP00000071594 | ENTREZGENE | |
ENSRNOP00000071594.1 | UniProtKB/TrEMBL | |
ENSRNOP00000080410.1 | UniProtKB/TrEMBL | |
Ensembl Transcript | ENSRNOT00000003249.7 | UniProtKB/TrEMBL |
ENSRNOT00000088921 | ENTREZGENE | |
ENSRNOT00000088921.2 | UniProtKB/TrEMBL | |
ENSRNOT00000096481.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 3.40.190.80 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Fructose-1,6-Bisphosphatase, subunit A, domain 1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
IMAGE_CLONE | IMAGE:7190529 | IMAGE-MGC_LOAD |
InterPro | Inositol_monoP_metal-BS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Inositol_monophosphatase-like | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Inositol_monophosphatase_CS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:64473 | UniProtKB/Swiss-Prot |
MGC_CLONE | MGC:93112 | IMAGE-MGC_LOAD |
NCBI Gene | 64473 | ENTREZGENE |
PANTHER | 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 | UniProtKB/Swiss-Prot |
3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 | UniProtKB/Swiss-Prot | |
3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 | UniProtKB/TrEMBL | |
3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 | UniProtKB/TrEMBL | |
Pfam | Inositol_P | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PhenoGen | Bpnt1 | PhenoGen |
PRINTS | IMPHPHTASES | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PROSITE | IMP_1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
IMP_2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Superfamily-SCOP | Carbohydrate phosphatase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
UniProt | A0A0G2K0V3 | ENTREZGENE, UniProtKB/TrEMBL |
A0A8I5ZPR2_RAT | UniProtKB/TrEMBL | |
A0A8L2Q072_RAT | UniProtKB/TrEMBL | |
BPNT1_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2008-09-26 | Bpnt1 | 3'(2'), 5'-bisphosphate nucleotidase 1 | Bpnt1 | bisphosphate 3'-nucleotidase 1 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2005-11-17 | Bpnt1 | bisphosphate 3'-nucleotidase 1 | Name updated | 1299863 | APPROVED | ||
2005-01-20 | Bpnt1 | 3'(2'),5'-bisphosphate nucleotidase | 3(2),5-bisphosphate nucleotidase | Name updated | 1299863 | APPROVED | |
2002-08-07 | Bpnt1 | 3(2),5-bisphosphate nucleotidase | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
Note Type | Note | Reference |
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gene_regulation | enzyme activity is dependent on Mg2+ and is inhibited by Ca2+ and Li+ ions | 632277 |