Pex3 (peroxisomal biogenesis factor 3)

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Gene: Pex3 (peroxisomal biogenesis factor 3) Rattus norvegicus

Analyze

Symbol:

Pex3

Name:

peroxisomal biogenesis factor 3

RGD ID:

621636

Description:

Predicted to enable lipid binding activity and protein-macromolecule adaptor activity. Involved in peroxisome membrane biogenesis. Located in cytosol and peroxisomal membrane. Human ortholog(s) of this gene implicated in peroxisomal biogenesis disorder and peroxisome biogenesis disorder 10A. Orthologous to human PEX3 (peroxisomal biogenesis factor 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; ammonium chloride.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

peroxin-3; peroxisomal assembly protein PEX3

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PEX3 (peroxisomal biogenesis factor 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Pex3 (peroxisomal biogenesis factor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pex3 (peroxisomal biogenesis factor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PEX3 (peroxisomal biogenesis factor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PEX3 (peroxisomal biogenesis factor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pex3 (peroxisomal biogenesis factor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PEX3 (peroxisomal biogenesis factor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PEX3 (peroxisomal biogenesis factor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pex3 (peroxisomal biogenesis factor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	PEX3 (peroxisomal biogenesis factor 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Pex3 (peroxisomal biogenesis factor 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pex3 (peroxisomal biogenesis factor 3)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	PEX3	Alliance	DIOPT (Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Pex3	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	prx-3	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	pex3	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	7,912,508 - 7,954,474 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	7,912,506 - 7,954,518 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	7,608,756 - 7,650,735 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	1	13,607,881 - 13,649,860 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	1	7,890,775 - 7,933,010 (-)	NCBI	Rnor_WKY
Rnor_6.0	1	7,685,209 - 7,726,238 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	7,685,338 - 7,726,401 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	9,313,347 - 9,354,522 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	8,316,117 - 8,357,955 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	8,316,120 - 8,357,955 (-)	NCBI
Celera	1	6,397,513 - 6,439,330 (-)	NCBI		Celera
Cytogenetic Map	1	p13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

familial hemophagocytic lymphohistiocytosis 4 (ISO)

genetic disease (ISO)

infantile Refsum disease (ISO)

peroxisomal biogenesis disorder (ISO)

peroxisome biogenesis disorder 10A (ISO)

Peroxisome Biogenesis Disorder 10B (ISO)

peroxisome biogenesis disorder 1A (ISO)

Zellweger syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

antimycin A (ISO)

aristolochic acid A (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP)

calcitriol (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chenodeoxycholic acid (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (ISO)

dicrotophos (ISO)

diuron (EXP)

elemental selenium (ISO)

fipronil (EXP)

folic acid (ISO)

inulin (ISO)

isotretinoin (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

Propiverine (EXP)

quercetin (ISO)

resveratrol (ISO)

selenium atom (ISO)

sunitinib (ISO)

testosterone (ISO)

thioacetamide (EXP)

triptonide (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

peroxisome membrane biogenesis (IDA)

peroxisome organization (IEA,IMP,ISO)

protein import into peroxisome membrane (IBA,ISO)

Cellular Component

cytosol (IDA,TAS)

endoplasmic reticulum (ISO)

nucleoplasm (ISO)

peroxisomal membrane (IDA,IEA,ISO,TAS)

peroxisome (IDA,ISO)

protein-containing complex (ISO)

protein-lipid complex (ISO)

Molecular Function

lipid binding (ISO)

protein binding (IPI,ISO)

protein-macromolecule adaptor activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	The peroxin pex3p initiates membrane assembly in peroxisome biogenesis.	Ghaedi K, etal., Mol Biol Cell 2000 Jun;11(6):2085-102.
3.	Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease.	Kikuchi M, etal., J Biol Chem. 2004 Jan 2;279(1):421-8. Epub 2003 Oct 15.
4.	The peroxisomal membrane protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p- and Pex16p-dependent pathway.	Matsuzaki T and Fujiki Y, J Cell Biol. 2008 Dec 29;183(7):1275-86. doi: 10.1083/jcb.200806062.
5.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:9657383	PMID:9922452	PMID:10430017	PMID:10527525	PMID:10958759	PMID:12924628	PMID:15007061	PMID:15489334	PMID:18174172	PMID:19479899	PMID:19686593	PMID:19715730
PMID:19946888	PMID:21525035	PMID:21768384

Genomics

Comparative Map Data

Pex3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	7,912,508 - 7,954,474 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	7,912,506 - 7,954,518 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	7,608,756 - 7,650,735 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	1	13,607,881 - 13,649,860 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	1	7,890,775 - 7,933,010 (-)	NCBI	Rnor_WKY
Rnor_6.0	1	7,685,209 - 7,726,238 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	7,685,338 - 7,726,401 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	9,313,347 - 9,354,522 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	8,316,117 - 8,357,955 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	8,316,120 - 8,357,955 (-)	NCBI
Celera	1	6,397,513 - 6,439,330 (-)	NCBI		Celera
Cytogenetic Map	1	p13	NCBI

PEX3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	143,450,805 - 143,490,616 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	6	143,450,805 - 143,490,616 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	143,771,942 - 143,811,753 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	143,813,810 - 143,852,838 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	143,813,809 - 143,852,834	NCBI
Celera	6	144,512,345 - 144,552,176 (+)	NCBI		Celera
Cytogenetic Map	6	q24.2	NCBI
HuRef	6	141,335,806 - 141,375,875 (+)	NCBI		HuRef
CHM1_1	6	144,034,452 - 144,074,661 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	144,643,215 - 144,683,024 (+)	NCBI		T2T-CHM13v2.0

Pex3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	13,399,586 - 13,428,886 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	13,399,586 - 13,428,886 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	13,523,842 - 13,553,142 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	13,523,842 - 13,553,142 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	13,243,648 - 13,272,948 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	13,214,314 - 13,243,291 (-)	NCBI		MGSCv36	mm8
Celera	10	13,424,011 - 13,452,957 (-)	NCBI		Celera
Cytogenetic Map	10	A2	NCBI

Pex3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955436	16,917,008 - 16,956,242 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955436	16,918,259 - 16,956,242 (-)	NCBI	ChiLan1.0	ChiLan1.0

PEX3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	6	161,327,988 - 161,367,495 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	141,226,738 - 141,266,233 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	145,947,954 - 145,987,194 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	145,947,954 - 145,987,188 (+)	Ensembl	panpan1.1		panPan2

PEX3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	34,994,092 - 35,030,453 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	34,994,197 - 35,023,975 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	35,892,376 - 35,928,520 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	35,169,295 - 35,212,126 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	35,169,269 - 35,209,374 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	35,037,632 - 35,073,783 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	34,920,560 - 34,956,715 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	35,232,840 - 35,268,988 (+)	NCBI		UU_Cfam_GSD_1.0

Pex3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	129,940,927 - 129,977,768 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936625	2,656,452 - 2,694,744 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936625	2,657,511 - 2,694,668 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PEX3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	21,766,000 - 21,802,182 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	21,750,194 - 21,801,625 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	24,137,242 - 24,188,753 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PEX3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	29,753,203 - 29,792,300 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	29,751,233 - 29,792,247 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	1,888,016 - 1,926,938 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pex3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624753	10,786,599 - 10,826,255 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624753	10,787,513 - 10,826,099 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Pex3
240 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	98
Count of miRNA genes:	74
Interacting mature miRNAs:	89
Transcripts:	ENSRNOT00000021524
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354647	Despr8	Despair related QTL 8		0.0000341	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	1	24744506	Rat
2298546	Neuinf4	Neuroinflammation QTL 4	5.1		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	1	1	28736750	Rat
2313053	Bss51	Bone structure and strength QTL 51	3.8	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	1	32356093	Rat
2313070	Bss52	Bone structure and strength QTL 52	4.4	0.0001	body length (VT:0001256)	body length (CMO:0000013)	1	1	32356093	Rat
2313090	Bmd69	Bone mineral density QTL 69	4.4	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	1	32356093	Rat
738020	Pia8	Pristane induced arthritis QTL 8	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	1	65833076	Rat
1578650	Bmd6	Bone mineral density QTL 6	12.2		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	1	509108	43284926	Rat
1578651	Bmd7	Bone mineral density QTL 7	14.2		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	1	509108	43284926	Rat
1578669	Bss9	Bone structure and strength QTL 9	6.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	1	509108	43284926	Rat
1554320	Bmd1	Bone mineral density QTL 1	12.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	509108	86060548	Rat
1600360	Mcs16	Mammary carcinoma susceptibility QTL 16	2.4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	2244390	43433040	Rat
1300170	Rf6	Renal function QTL 6	3.14		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	1	4162807	11481482	Rat
7421626	Bp360	Blood pressure QTL 360		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	4393289	49393289	Rat
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	5925874	115540829	Rat
4889451	Eae29	Experimental allergic encephalomyelitis QTL 29	5.51		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	1	5925877	24697545	Rat

Markers in Region

RH142832

Rat Assembly	Chr	Position (strand)	Source	JBrowse
RH 3.4 Map	1	103.72	UniSTS
Cytogenetic Map	1	p13	UniSTS

RH141589

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	7,912,731 - 7,912,947 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	7,685,433 - 7,685,648	NCBI	Rnor6.0
Rnor_5.0	1	9,313,571 - 9,313,786	UniSTS	Rnor5.0
RGSC_v3.4	1	8,316,341 - 8,316,556	UniSTS	RGSC3.4
Celera	1	6,397,737 - 6,397,952	UniSTS
RH 3.4 Map	1	102.5	UniSTS
Cytogenetic Map	1	p13	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	36	54	38	19	38			74	35	41	11
Low		7	3	3		3	8	11					8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_031350	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092487	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092495	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB035306	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC062046	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473994	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000021524 ⟹ ENSRNOP00000021524

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	7,912,506 - 7,954,518 (-)	Ensembl
Rnor_6.0 Ensembl	1	7,685,338 - 7,726,401 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000114484 ⟹ ENSRNOP00000096147

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	7,914,087 - 7,954,518 (-)	Ensembl

RefSeq Acc Id:

NM_031350 ⟹ NP_112640

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	7,912,508 - 7,954,348 (-)	NCBI
Rnor_6.0	1	7,685,209 - 7,726,238 (-)	NCBI
Rnor_5.0	1	9,313,347 - 9,354,522 (-)	NCBI
RGSC_v3.4	1	8,316,117 - 8,357,955 (-)	RGD
Celera	1	6,397,513 - 6,439,330 (-)	RGD

Sequence:

show sequence

GAATTCCCGGGCCAGATTGACGGAAGACACGGTTTCCTGGTGAGCCAGTCCCTCTCCCCTAGGC
AACCCACACAACCCGGGGTCTGAAGATGCTGAGATCAATGTGGAATTTTCTGAAACGTCACAAA
AAGAAATGCATCTTCCTGGGCACAGTCCTTGGAGGAGTCTATATCCTGGGAAAATATGGACAGA
AAAAACTTAGAGAAATACAAGAAAGAGAAGCTGCAGAGTACATTGCCCAAGCTCGGCGACAGTA
CCATTTTGAAAGTAACCAGAGGACTTGCAATATGACAGTGCTGTCCATGCTGCCAACACTGAGA
GAGGCCTTAATGCAGCAGCTCAACTCGGAGAGTCTGACAGCTTTGTTGAAAAACAGGCCTTCAA
ACAAGCTGGAAATATGGGAGGATCTAAAGATAATAAGTTTCACAAGAAGTATTGTAGCTGTGTA
CAGCACATGTATGCTGGTGGTTCTTTTGCGAGTCCAGCTGAACATAATTGGTGGATATATTTAC
CTGGATAATGCAACAGTTGGCAAAAATGGCACTAGCATCCTAGCTCCCCCAGATGTACAGCAAC
AGTATTTATCAAGTATTCAACACCTCCTTGGAGATGGCCTGACAGAGTTGGTCACTGTCATTAA
ACAAGCTGTGCAGAGGATCTTAGGAAGTATTTCTCTTAAACATTCCTTGTCCCTTTTGGACTTG
GAGCAGAAACTGAAAGAAATAAGAACTCTTGTTGAGCAACATCGATCTTGCTGGAATGATAAAG
ACGCATCCAAGTCTTCCCTGTGCCACTACATGATGCCAGACGAGGAGACGCCGCTGGCAGCGCA
GGCTTATGGGCTTTCTCCCAGAGATATTACCACTATTAAACTTCTCAATGAGACAAGAGACATG
CTGGAAAGTCCAGATTTCAGTACAGTTCTGAATACCTGTTTAAACAGAGGCTTCAGTCGGCTTC
TAGACAATATGGCGGAGTTCTTCCGACCCACTGAGCAGGACCTGCAGCATGGTAACTCCATAAA
CAGTCTGTCCAGTGTCAGCCTCCCTTTAGCCAAGATAATCCCCATAGTGAATGGACAGATCCAC
TCCGTCTGCAGTGAGACACCCAGTCACTTCGTGCAGGATCTGCTGATGATGGAGCAAGTGAAAG
ACTTTGCTGCCAACGTGTACGAAGCATTCAGCACCCCCCAACAACTGGAGAAATGATTGTTTTC
TTTCAAGAAAAACCACAGTGGATTCATCTACATTAAAAAGTACTCTGAATAAATCACCTATACC
TAGAGTGACAATTTGCAACCAAATGCCTAATAAAATATATTCTTGAGCCAATCTTCATCTCATA
AGTAGATTCATTTAGCACCTTACTGTATTTTTAATTCAGCACAGTCTACTTCTTCAGGTGTATC
TAACTGTGCAGAGATCACGTCAGCATCAATCATGATTCCCTTAAAGTCTGGATAGCTGATCCAA
ACAAGTAGGGCTTTTATACATACATGGAATGGAATGTGGTGTCCTTTCACACATGTAATGAGGG
AAAATCTGTCTTGAAAAGGAGATCTAGGCTGTTTAACTAATTATGGCGTTTCCTGGANTCTGAA
GTAAGCAAGAGCAAGCCAGATCCTCTTCAGTCGCCCTTAGAAGGCACCCGTGATTTGCTCACAC
ATACCTACGCAGGGGCTTATTTTCTAGAAATGAGTGGGTTTCCACACCTGTGGTCACTTACTTC
TCTGCACTGTCCTGTCAGTATTTATTTGCAGCATTTTCTAAGCTTCATTAGCAGCCCTCAGAAG
GCTGCATATAGATTCTTCAAGCTAATGTTTATGTTGTTTACTCACAATTATTAATAATTACAGG
TTTATTCATTTATGTATAAATTTAATAACTTTGTATTAATTTTGAGTATAATAAGTTGTTACAA
TAAACTATTTTAATAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039092487 ⟹ XP_038948415

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	7,913,299 - 7,954,474 (-)	NCBI

RefSeq Acc Id:

XM_039092495 ⟹ XP_038948423

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	7,913,275 - 7,954,474 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_112640	(Get FASTA)	NCBI Sequence Viewer
	XP_038948415	(Get FASTA)	NCBI Sequence Viewer
	XP_038948423	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH62046	(Get FASTA)	NCBI Sequence Viewer
	BAA97992	(Get FASTA)	NCBI Sequence Viewer
	EDL93733	(Get FASTA)	NCBI Sequence Viewer
	Q9JJK4	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_112640 ⟸ NM_031350

- UniProtKB:

Q9JJK4 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MLRSMWNFLKRHKKKCIFLGTVLGGVYILGKYGQKKLREIQEREAAEYIAQARRQYHFESNQRT
CNMTVLSMLPTLREALMQQLNSESLTALLKNRPSNKLEIWEDLKIISFTRSIVAVYSTCMLVVL
LRVQLNIIGGYIYLDNATVGKNGTSILAPPDVQQQYLSSIQHLLGDGLTELVTVIKQAVQRILG
SISLKHSLSLLDLEQKLKEIRTLVEQHRSCWNDKDASKSSLCHYMMPDEETPLAAQAYGLSPRD
ITTIKLLNETRDMLESPDFSTVLNTCLNRGFSRLLDNMAEFFRPTEQDLQHGNSINSLSSVSLP
LAKIIPIVNGQIHSVCSETPSHFVQDLLMMEQVKDFAANVYEAFSTPQQLEK

hide sequence

RefSeq Acc Id:

ENSRNOP00000021524 ⟸ ENSRNOT00000021524

RefSeq Acc Id:	XP_038948423 ⟸ XM_039092495
- Peptide Label:	isoform X2
- UniProtKB:	A0A8L2QAW4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038948415 ⟸ XM_039092487
- Peptide Label:	isoform X1

RefSeq Acc Id:

ENSRNOP00000096147 ⟸ ENSRNOT00000114484

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9JJK4-F1-model_v2	AlphaFold	Q9JJK4	1-372	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689496

Promoter ID:

EPDNEW_R21

Type:

multiple initiation site

Name:

Pex3_1

Description:

peroxisomal biogenesis factor 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	7,726,385 - 7,726,445	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621636	AgrOrtholog
BioCyc Gene	G2FUF-62360	BioCyc
Ensembl Genes	ENSRNOG00000015660	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000021524	ENTREZGENE
	ENSRNOP00000021524.3	UniProtKB/TrEMBL
	ENSRNOP00000096147.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000021524	ENTREZGENE
	ENSRNOT00000021524.5	UniProtKB/TrEMBL
	ENSRNOT00000114484.1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:5597999	IMAGE-MGC_LOAD
InterPro	Peroxin-3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:83519	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:72404	IMAGE-MGC_LOAD
NCBI Gene	83519	ENTREZGENE
PANTHER	PEROXISOMAL BIOGENESIS FACTOR 3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR28080	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Peroxin-3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Pex3	PhenoGen
UniProt	A0A8I6AUP3_RAT	UniProtKB/TrEMBL
	A0A8L2QAW4	ENTREZGENE, UniProtKB/TrEMBL
	PEX3_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Pex3	peroxisomal biogenesis factor 3			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Pex3	peroxisomal biogenesis factor 3			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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