Gene: Aldh6a1 (aldehyde dehydrogenase 6 family, member A1) Rattus norvegicus
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Symbol: Aldh6a1
Name: aldehyde dehydrogenase 6 family, member A1
Description: ENCODES a protein that exhibits malonate-semialdehyde dehydrogenase (acetylating) activity; methylmalonate-semialdehyde dehydrogenase (acylating) activity; thiolester hydrolase activity; INVOLVED IN beta-alanine catabolic process; thymine catabolic process; thymine metabolic process; PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; ASSOCIATED WITH amino acid metabolic disorder (ortholog); Methylmalonate Semialdehyde Dehydrogenase Deficiency (ortholog); Myocardial Ischemia (ortholog); FOUND IN mitochondrion (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: aldehyde dehydrogenase family 6 member A1; aldehyde dehydrogenase family 6, subfamily A1; malonate-semialdehyde dehydrogenase; methylmalonate semialdehyde dehydrogenase; methylmalonate semialdehyde dehydrogenase gene; methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; Mmsdh
Orthologs:
Homo sapiens (human) : ALDH6A1 (aldehyde dehydrogenase 6 family member A1)  HGNC  Alliance
Mus musculus (house mouse) : Aldh6a1 (aldehyde dehydrogenase family 6, subfamily A1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aldh6a1 (aldehyde dehydrogenase 6 family member A1)
Pan paniscus (bonobo/pygmy chimpanzee) : ALDH6A1 (aldehyde dehydrogenase 6 family member A1)
Canis lupus familiaris (dog) : ALDH6A1 (aldehyde dehydrogenase 6 family member A1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aldh6a1 (aldehyde dehydrogenase 6 family member A1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.06108,146,552 - 108,167,185 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06117,379,212 - 117,399,845 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46108,495,781 - 108,516,414 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16108,500,592 - 108,736,789 (-)NCBI
Celera6101,905,993 - 101,926,661 (-)NCBICelera
Cytogenetic Map6q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Aldh6a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621556
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-08-08
Status: ACTIVE