Gene: Aldh6a1 (aldehyde dehydrogenase 6 family, member A1) Rattus norvegicus
Symbol: Aldh6a1
Name: aldehyde dehydrogenase 6 family, member A1
Description: ENCODES a protein that exhibits malonate-semialdehyde dehydrogenase (acetylating) activity; methylmalonate-semialdehyde dehydrogenase (acylating) activity; thiolester hydrolase activity; INVOLVED IN beta-alanine catabolic process; thymine catabolic process; thymine metabolic process; PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; ASSOCIATED WITH Amino Acid Metabolism, Inborn Errors (ortholog); Heart Septal Defects, Ventricular (ortholog); Methylmalonate Semialdehyde Dehydrogenase Deficiency (ortholog); FOUND IN mitochondrion (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: aldehyde dehydrogenase family 6 member A1; aldehyde dehydrogenase family 6, subfamily A1; malonate-semialdehyde dehydrogenase; methylmalonate semialdehyde dehydrogenase; methylmalonate semialdehyde dehydrogenase gene; methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; Mmsdh
Homo sapiens (human) : ALDH6A1 (aldehyde dehydrogenase 6 family member A1)  HGNC  Alliance
Mus musculus (house mouse) : Aldh6a1 (aldehyde dehydrogenase family 6, subfamily A1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aldh6a1 (aldehyde dehydrogenase 6 family member A1)
Pan paniscus (bonobo/pygmy chimpanzee) : ALDH6A1 (aldehyde dehydrogenase 6 family member A1)
Canis lupus familiaris (dog) : ALDH6A1 (aldehyde dehydrogenase 6 family member A1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aldh6a1 (aldehyde dehydrogenase 6 family member A1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.06108,146,552 - 108,167,185 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06117,379,212 - 117,399,845 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46108,495,781 - 108,516,414 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16108,500,592 - 108,736,789 (-)NCBI
Celera6101,905,993 - 101,926,661 (-)NCBICelera
Cytogenetic Map6q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Aldh6a1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621556
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-03-20
Status: ACTIVE