Gene: Rpe65 (RPE65, retinoid isomerohydrolase) Rattus norvegicus
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Symbol: Rpe65
Name: RPE65, retinoid isomerohydrolase
Description: ENCODES a protein that exhibits all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity; cardiolipin binding (ortholog); phosphatidylcholine binding (ortholog); INVOLVED IN camera-type eye development; circadian rhythm; neural retina development; PARTICIPATES IN retinoid cycle metabolic pathway; altered retinoid cycle metabolic pathway; retinitis pigmentosa pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental; Amaurosis Congenita of Leber, Type 2 (ortholog); basal cell carcinoma (ortholog); FOUND IN cell body; membrane (ortholog); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; all-trans-retinal
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: all-trans-retinyl-palmitate hydrolase; retinal pigment epithelium 65; retinal pigment epithelium 65-like; retinal pigment epithelium, 65 kDa; retinal pigment epithelium-specific 65 kDa protein; retinal pigment epithelium-specific protein 65; retinoid isomerohydrolase; retinol isomerase
Orthologs:
Homo sapiens (human) : RPE65 (RPE65, retinoid isomerohydrolase)  HGNC  AGR
Mus musculus (house mouse) : Rpe65 (retinal pigment epithelium 65)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Rpe65 (RPE65, retinoid isomerohydrolase)
Pan paniscus (bonobo/pygmy chimpanzee) : RPE65 (RPE65, retinoid isomerohydrolase)
Canis lupus familiaris (dog) : RPE65 (RPE65, retinoid isomerohydrolase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rpe65 (RPE65, retinoid isomerohydrolase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02266,141,581 - 266,169,197 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.02284,774,159 - 284,804,254 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.12257,860,998 - 257,893,921 (+)NCBI
Celera2240,512,281 - 240,537,640 (+)NCBI
Cytogenetic Map2q45NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
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AGR Gene
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RGD Object Information
RGD ID: 621396
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE