Gene: Pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha) Rattus norvegicus
Analyze
Symbol: Pik3ca
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
Description: ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase activity; insulin receptor substrate binding (ortholog); kinase activity (ortholog); INVOLVED IN phosphatidylinositol phosphorylation; positive regulation of smooth muscle cell proliferation; response to butyrate; PARTICIPATES IN adenosine signaling pathway; altered phosphatidylinositol 3-kinase signaling pathway; altered phosphatidylinositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH Polycystic Kidney, Autosomal Recessive; Acyl-CoA Dehydrogenase Family, Member 9, Deficiency of (ortholog); Adenocarcinoma (ortholog); FOUND IN phosphatidylinositol 3-kinase complex; lamellipodium (ortholog); phosphatidylinositol 3-kinase complex, class IA (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; all-trans-retinoic acid; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC116320; p110alpha; phosphatidylinositol 3-kinase, catalytic, alpha polypeptide; phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; phosphoinositide-3-kinase catalytic alpha polypeptide; phosphoinositide-3-kinase, catalytic, alpha polypeptide; PI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; ptdIns-3-kinase subunit alpha; ptdIns-3-kinase subunit p110-alpha; serine/threonine protein kinase PIK3CA
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02118,831,350 - 118,861,456 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02138,491,967 - 138,521,934 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42118,640,277 - 118,672,440 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12118,603,330 - 118,613,969 (+)NCBI
Celera2110,329,861 - 110,360,075 (+)NCBICelera
Cytogenetic Map2q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Pik3ca
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620916
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE