Gene: Ltc4s (leukotriene C4 synthase) Rattus norvegicus
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Symbol: Ltc4s
Name: leukotriene C4 synthase
Description: ENCODES a protein that exhibits glutathione binding; leukotriene-C4 synthase activity; protein heterodimerization activity; INVOLVED IN cellular response to lipopolysaccharide; cellular response to vitamin A; leukotriene biosynthetic process; PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH Glomerulonephritis; Liver Failure, Acute; Peripheral Nervous System Diseases; FOUND IN intracellular membrane-bounded organelle; endoplasmic reticulum (ortholog); nuclear envelope (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 7,12-dimethyltetraphene; ammonium chloride
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: leukotriene-C(4) synthase; LTC4 synthase
Orthologs:
Homo sapiens (human) : LTC4S (leukotriene C4 synthase)  HGNC  AGR
Mus musculus (house mouse) : Ltc4s (leukotriene C4 synthase)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Ltc4s (leukotriene C4 synthase)
Pan paniscus (bonobo/pygmy chimpanzee) : LTC4S (leukotriene C4 synthase)
Canis lupus familiaris (dog) : LTC4S (leukotriene C4 synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ltc4s (leukotriene C4 synthase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01035,736,486 - 35,743,088 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01035,498,195 - 35,506,088 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41035,786,877 - 35,788,838 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11035,787,925 - 35,789,881 (-)NCBI
Celera1033,909,805 - 33,911,766 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ltc4s
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620677
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE