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Gene: Dcx (doublecortin) Rattus norvegicus
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Symbol: Dcx
Name: doublecortin
RGD ID: 620670
Description: Predicted to have microtubule binding activity and protein kinase binding activity. Involved in nervous system development; positive regulation of endocytosis; and response to electrical stimulus. Localizes to dendrite; growth cone; and neuronal cell body. Colocalizes with microtubule. Used to study visual epilepsy. Biomarker of hypothyroidism and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in lissencephaly and subcortical band heterotopia. Orthologous to human DCX (doublecortin); INTERACTS WITH 2,6-di-tert-butyl-4-methylphenol; 5-fluorouracil; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: neuronal migration protein doublecortin
Orthologs:
Homo sapiens (human) : DCX (doublecortin)  HGNC  Alliance
Mus musculus (house mouse) : Dcx (doublecortin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dcx (doublecortin)
Pan paniscus (bonobo/pygmy chimpanzee) : DCX (doublecortin)
Canis lupus familiaris (dog) : DCX (doublecortin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dcx (doublecortin)
Sus scrofa (pig) : DCX (doublecortin)
Chlorocebus sabaeus (African green monkey) : DCX (doublecortin)
Heterocephalus glaber (naked mole-rat) : Dcx (doublecortin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X115,098,675 - 115,175,515 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX115,098,675 - 115,175,299 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X113,551,874 - 113,628,283 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X34,596,262 - 34,672,383 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X34,649,730 - 34,718,439NCBI
CeleraX106,829,783 - 106,906,206 (-)NCBICelera
Cytogenetic MapXq33-q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Dcx
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620670
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.