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Gene: Dcx (doublecortin) Rattus norvegicus
Symbol: Dcx
Name: doublecortin
RGD ID: 620670
Description: Predicted to have microtubule binding activity and protein kinase binding activity. Involved in nervous system development; positive regulation of endocytosis; and response to electrical stimulus. Localizes to dendrite; growth cone; and neuronal cell body. Colocalizes with microtubule. Used to study visual epilepsy. Biomarker of hypothyroidism and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in lissencephaly and subcortical band heterotopia. Orthologous to human DCX (doublecortin); INTERACTS WITH 2,6-di-tert-butyl-4-methylphenol; 5-fluorouracil; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: neuronal migration protein doublecortin
Homo sapiens (human) : DCX (doublecortin)  HGNC  Alliance
Mus musculus (house mouse) : Dcx (doublecortin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dcx (doublecortin)
Pan paniscus (bonobo/pygmy chimpanzee) : DCX (doublecortin)
Canis lupus familiaris (dog) : DCX (doublecortin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dcx (doublecortin)
Sus scrofa (pig) : DCX (doublecortin)
Chlorocebus sabaeus (African green monkey) : DCX (doublecortin)
Heterocephalus glaber (naked mole-rat) : Dcx (doublecortin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X115,098,675 - 115,175,515 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX115,098,675 - 115,175,299 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X113,551,874 - 113,628,283 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X34,596,262 - 34,672,383 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X34,649,730 - 34,718,439NCBI
CeleraX106,829,783 - 106,906,206 (-)NCBICelera
Cytogenetic MapXq33-q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Dcx
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620670
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.