Gene: Cyp2d4 (cytochrome P450, family 2, subfamily d, polypeptide 4) Rattus norvegicus
Symbol: Cyp2d4
Name: cytochrome P450, family 2, subfamily d, polypeptide 4
Description: ENCODES a protein that exhibits arachidonic acid monooxygenase activity; monooxygenase activity; steroid 21-monooxygenase activity; INVOLVED IN arachidonic acid metabolic process; dopamine biosynthetic process; dopamine metabolic process; PARTICIPATES IN celecoxib pharmacodynamics pathway; celecoxib pharmacokinetics pathway; citalopram pharmacodynamics pathway; ASSOCIATED WITH abnormal motor capabilities/coordination/movement; ASSOCIATED WITH Acute Kidney Injury (ortholog); Alzheimer Disease (ortholog); Amphetamine-Related Disorders (ortholog); FOUND IN intracellular membrane-bounded organelle; cytoplasm (ortholog); mitochondrion (ortholog); INTERACTS WITH (S)-duloxetine hydrochloride; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol
Type: protein-coding
Also known as: Cyp2d18; Cyp2d22; Cyp2d4v1; Cyp2d4v2; Cyp2d6; Cyp2d6_mapped; CYPIID18; CYPIID4; cytochrome P450 2D-29; cytochrome P450 2D-35; cytochrome P450 2D18; cytochrome P450 2D4; Cytochrome P450 subfamily IID4; cytochrome P450, family 2, subfamily d, polypeptide 22; cytochrome P450, subfamily 2D, polypeptide 6; Cytochrome P450, subfamily IID, polypeptide 6; cytochrome P450, subfamily IID, polypeptide 6 (mapped); Cytochrome P450, subfamily IID4; cytochrome P450-CMF3; cytochrome P450-DB4; debrisoquine 4-hydroxylase; P450 2D-29/2D-35; P450-CMF3; P450-DB4
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07123,599,264 - 123,608,436 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07123,583,983 - 123,593,008 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47120,742,273 - 120,752,274 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17120,775,536 - 120,786,502 (-)NCBI
Celera7110,197,422 - 110,206,650 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cyp2d4
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620640
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE