Gene: Slc7a5 (solute carrier family 7 member 5) Rattus norvegicus
Symbol: Slc7a5
Name: solute carrier family 7 member 5
Description: ENCODES a protein that exhibits amino acid transmembrane transporter activity (ortholog); L-amino acid transmembrane transporter activity (ortholog); peptide antigen binding (ortholog); INVOLVED IN L-amino acid transport (ortholog); neutral amino acid transport (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH 16Q24.3 Microdeletion Syndrome (ortholog); Dermatitis, Allergic Contact (ortholog); Lung Neoplasms (ortholog); FOUND IN cytosol (ortholog); intracellular membrane-bounded organelle (ortholog); plasma membrane (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether
Type: protein-coding
Also known as: 4F2 LC; 4F2 light chain; 4F2LC; E16; integral membrane protein E16; L-type amino acid transporter 1; large neutral amino acids transporter small subunit 1; solute carrier family 7 (amino acid transporter light chain, L system), member 5; solute carrier family 7 (cationic amino acid transporter, y+ system), member 5; TA1; TA1/LAT-1/CD98 light chain region; tumor-associated protein 1
Homo sapiens (human) : SLC7A5 (solute carrier family 7 member 5)  HGNC  AGR
Mus musculus (house mouse) : Slc7a5 (solute carrier family 7 (cationic amino acid transporter, y+ system), member 5)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Slc7a5 (solute carrier family 7 member 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC7A5 (solute carrier family 7 member 5)
Canis lupus familiaris (dog) : SLC7A5 (solute carrier family 7 member 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc7a5 (solute carrier family 7 member 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01954,693,959 - 54,722,563 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01965,412,970 - 65,441,647 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41952,120,728 - 52,149,332 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11952,125,608 - 52,154,213 (-)NCBI
Celera1949,180,586 - 49,208,780 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Slc7a5
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620639
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE