Pou6f1 (POU class 6 homeobox 1) - Rat Genome Database

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Gene: Pou6f1 (POU class 6 homeobox 1) Rattus norvegicus
Analyze
Symbol: Pou6f1
Name: POU class 6 homeobox 1
RGD ID: 620615
Description: Enables DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in actin cytoskeleton and nuclear body. Orthologous to human POU6F1 (POU class 6 homeobox 1); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: brain-5; brain-specific homeobox/POU domain protein 5; brn-5 protein; Brn5; POU domain, class 6, transcription factor 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87133,556,506 - 133,580,004 (-)NCBIGRCr8
mRatBN7.27131,677,719 - 131,700,869 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7131,677,719 - 131,701,101 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl7131,680,141 - 131,686,843 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7133,482,252 - 133,489,011 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07135,707,827 - 135,714,586 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07135,621,490 - 135,628,243 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07142,201,614 - 142,225,256 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7142,204,036 - 142,210,738 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07140,006,269 - 140,030,316 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47139,325,783 - 139,332,485 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17139,402,219 - 139,408,918 (-)NCBI
Celera7128,155,577 - 128,162,279 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Brn-5 is a divergent POU domain factor highly expressed in layer IV of the neocortex. Andersen B, etal., J Biol Chem 1993 Nov 5;268(31):23390-8.
2. Expression of the POU transcription factor Brn-5 is an early event in the terminal differentiation of CNS neurons. Cui H and Bulleit RF, J Neurosci Res 1998 Jun 15;52(6):625-32.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. A human POU domain gene, mPOU, is expressed in developing brain and specific adult tissues. Wey E, etal., Eur J Biochem 1994 Mar 15;220(3):753-62.
Additional References at PubMed
PMID:8463278   PMID:8645295   PMID:15024082   PMID:17933456   PMID:36317259  


Genomics

Comparative Map Data
Pou6f1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87133,556,506 - 133,580,004 (-)NCBIGRCr8
mRatBN7.27131,677,719 - 131,700,869 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7131,677,719 - 131,701,101 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl7131,680,141 - 131,686,843 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7133,482,252 - 133,489,011 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07135,707,827 - 135,714,586 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07135,621,490 - 135,628,243 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07142,201,614 - 142,225,256 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7142,204,036 - 142,210,738 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07140,006,269 - 140,030,316 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47139,325,783 - 139,332,485 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17139,402,219 - 139,408,918 (-)NCBI
Celera7128,155,577 - 128,162,279 (-)NCBICelera
Cytogenetic Map7q36NCBI
POU6F1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381251,186,936 - 51,218,062 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1251,186,936 - 51,218,062 (-)EnsemblGRCh38hg38GRCh38
GRCh371251,580,719 - 51,611,846 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361249,869,232 - 49,897,744 (-)NCBINCBI36Build 36hg18NCBI36
Build 341249,869,231 - 49,897,744NCBI
Celera1250,382,323 - 50,412,965 (-)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1248,613,565 - 48,644,376 (-)NCBIHuRef
CHM1_11251,546,938 - 51,577,697 (-)NCBICHM1_1
T2T-CHM13v2.01251,149,818 - 51,180,972 (-)NCBIT2T-CHM13v2.0
Pou6f1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915100,473,199 - 100,497,949 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15100,473,199 - 100,497,865 (-)EnsemblGRCm39 Ensembl
GRCm3815100,575,318 - 100,600,061 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15100,575,318 - 100,599,984 (-)EnsemblGRCm38mm10GRCm38
MGSCv3715100,405,749 - 100,416,796 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3615100,403,352 - 100,414,399 (-)NCBIMGSCv36mm8
Celera15102,728,946 - 102,740,065 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.35NCBI
Pou6f1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555471,685,365 - 1,704,994 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555471,685,365 - 1,712,028 (-)NCBIChiLan1.0ChiLan1.0
POU6F1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21042,968,226 - 42,999,070 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11242,964,989 - 42,995,832 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01237,535,656 - 37,566,481 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11238,419,517 - 38,472,746 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1238,430,434 - 38,472,746 (+)Ensemblpanpan1.1panPan2
POU6F1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1273,646,255 - 3,669,780 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl273,649,424 - 3,666,855 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2742,586,324 - 42,615,830 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0273,687,455 - 3,716,983 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl273,698,849 - 3,716,932 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1273,663,568 - 3,684,080 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0273,650,695 - 3,671,231 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02742,983,324 - 43,012,809 (-)NCBIUU_Cfam_GSD_1.0
Pou6f1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494564,353,527 - 64,372,248 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365128,795,272 - 8,810,484 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365128,795,650 - 8,811,220 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POU6F1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.2517,222,730 - 17,239,769 (+)NCBISscrofa10.2Sscrofa10.2susScr3
POU6F1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11147,389,111 - 47,417,640 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037198,679,739 - 198,711,665 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pou6f1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248161,058,851 - 1,076,322 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248161,048,185 - 1,076,322 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pou6f1
99 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:254
Count of miRNA genes:167
Interacting mature miRNAs:194
Transcripts:ENSRNOT00000006095
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat

Markers in Region
RH143890  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27131,695,776 - 131,695,923 (+)MAPPERmRatBN7.2
Rnor_6.07142,219,672 - 142,219,818NCBIRnor6.0
Rnor_5.07140,024,327 - 140,024,473UniSTSRnor5.0
RGSC_v3.47139,342,113 - 139,342,259UniSTSRGSC3.4
Celera7128,171,213 - 128,171,359UniSTS
RH 3.4 Map71074.3UniSTS
Cytogenetic Map7q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 62 6 12 2
Low 3 43 53 37 18 37 8 11 12 29 24 9 8
Below cutoff 4 4 4 5

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001105746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L23204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000006095   ⟹   ENSRNOP00000006095
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7131,680,141 - 131,686,843 (-)Ensembl
Rnor_6.0 Ensembl7142,204,036 - 142,210,738 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100238   ⟹   ENSRNOP00000080135
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7131,677,719 - 131,701,101 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000114805   ⟹   ENSRNOP00000085229
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7131,685,991 - 131,701,000 (-)Ensembl
RefSeq Acc Id: NM_001105746   ⟹   NP_001099216
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87133,558,928 - 133,565,630 (-)NCBI
mRatBN7.27131,680,141 - 131,686,843 (-)NCBI
Rnor_6.07142,204,036 - 142,210,738 (-)NCBI
Rnor_5.07140,006,269 - 140,030,316 (-)NCBI
RGSC_v3.47139,325,783 - 139,332,485 (-)RGD
Celera7128,155,577 - 128,162,279 (-)RGD
Sequence:
RefSeq Acc Id: XM_017594569   ⟹   XP_017450058
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87133,556,506 - 133,566,014 (-)NCBI
mRatBN7.27131,677,719 - 131,687,222 (-)NCBI
Rnor_6.07142,201,614 - 142,211,214 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039078243   ⟹   XP_038934171
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87133,556,506 - 133,580,004 (-)NCBI
mRatBN7.27131,677,719 - 131,700,862 (-)NCBI
RefSeq Acc Id: XM_039078244   ⟹   XP_038934172
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87133,556,506 - 133,580,004 (-)NCBI
mRatBN7.27131,677,719 - 131,700,869 (-)NCBI
RefSeq Acc Id: XM_039078245   ⟹   XP_038934173
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87133,556,506 - 133,579,473 (-)NCBI
mRatBN7.27131,677,719 - 131,700,862 (-)NCBI
RefSeq Acc Id: XM_039078246   ⟹   XP_038934174
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87133,556,506 - 133,580,004 (-)NCBI
mRatBN7.27131,677,719 - 131,700,862 (-)NCBI
RefSeq Acc Id: XM_039078247   ⟹   XP_038934175
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87133,564,785 - 133,579,481 (-)NCBI
mRatBN7.27131,685,998 - 131,700,862 (-)NCBI
RefSeq Acc Id: XM_039078248   ⟹   XP_038934176
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87133,556,506 - 133,579,471 (-)NCBI
mRatBN7.27131,677,719 - 131,696,007 (-)NCBI
RefSeq Acc Id: XM_063262864   ⟹   XP_063118934
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87133,556,506 - 133,579,472 (-)NCBI
RefSeq Acc Id: XM_063262865   ⟹   XP_063118935
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87133,556,506 - 133,579,472 (-)NCBI
RefSeq Acc Id: XM_063262866   ⟹   XP_063118936
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87133,556,506 - 133,571,518 (-)NCBI
RefSeq Acc Id: XR_010052928
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87133,556,506 - 133,579,472 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001099216   ⟸   NM_001105746
- UniProtKB: P56223 (UniProtKB/Swiss-Prot),   A6KCK3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450058   ⟸   XM_017594569
- Peptide Label: isoform X5
- UniProtKB: P56223 (UniProtKB/Swiss-Prot),   A6KCK3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000006095   ⟸   ENSRNOT00000006095
RefSeq Acc Id: XP_038934172   ⟸   XM_039078244
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038934174   ⟸   XM_039078246
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038934173   ⟸   XM_039078245
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038934171   ⟸   XM_039078243
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038934176   ⟸   XM_039078248
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038934175   ⟸   XM_039078247
- Peptide Label: isoform X4
RefSeq Acc Id: ENSRNOP00000080135   ⟸   ENSRNOT00000100238
RefSeq Acc Id: ENSRNOP00000085229   ⟸   ENSRNOT00000114805
RefSeq Acc Id: XP_063118935   ⟸   XM_063262865
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063118934   ⟸   XM_063262864
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063118936   ⟸   XM_063262866
- Peptide Label: isoform X7
Protein Domains
Homeobox   POU-specific

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P56223-F1-model_v2 AlphaFold P56223 1-301 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620615 AgrOrtholog
BioCyc Gene G2FUF-32015 BioCyc
Ensembl Genes ENSRNOG00000004595 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00000070769 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00055026568 UniProtKB/Swiss-Prot
  ENSRNOG00060015006 UniProtKB/Swiss-Prot
  ENSRNOG00065020685 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000006095 ENTREZGENE
  ENSRNOT00000006095.7 UniProtKB/Swiss-Prot
  ENSRNOT00000100238.1 UniProtKB/TrEMBL
  ENSRNOT00000114805.1 UniProtKB/TrEMBL
  ENSRNOT00055045850 UniProtKB/Swiss-Prot
  ENSRNOT00060025710 UniProtKB/Swiss-Prot
  ENSRNOT00065035048 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.260.40 UniProtKB/Swiss-Prot
  Homeodomain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  lambda repressor-like DNA-binding domains UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lambda_DNA-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  POU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  POU_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:116545 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 116545 ENTREZGENE
PANTHER POU DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  POU DOMAIN, CLASS 6, TRANSCRIPTION FACTOR 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pou UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pou6f1 PhenoGen
PRINTS POUDOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE HOMEOBOX_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  POU_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  POU_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  POU_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004595 RatGTEx
  ENSRNOG00000070769 RatGTEx
  ENSRNOG00055026568 RatGTEx
  ENSRNOG00060015006 RatGTEx
  ENSRNOG00065020685 RatGTEx
SMART HOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  POU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Homeodomain-like UniProtKB/TrEMBL
  lambda repressor-like DNA-binding domains UniProtKB/TrEMBL
  SSF46689 UniProtKB/Swiss-Prot
  SSF47413 UniProtKB/Swiss-Prot
UniProt A0A8I5ZPH6_RAT UniProtKB/TrEMBL
  A0A8I6GCM2_RAT UniProtKB/TrEMBL
  A6KCK3 ENTREZGENE, UniProtKB/TrEMBL
  P56223 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-24 Pou6f1  POU class 6 homeobox 1  Pou6f1  POU domain, class 6, transcription factor 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Pou6f1  POU domain, class 6, transcription factor 1      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Pou6f1  POU domain, class 6, transcription factor 1      Symbol and Name status set to provisional 70820 PROVISIONAL