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Gene: Lmnb1 (lamin B1) Rattus norvegicus
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Symbol: Lmnb1
Name: lamin B1
Description: Predicted to have phospholipase binding activity and sequence-specific double-stranded DNA binding activity. Involved in several processes, including cellular response to corticosterone stimulus; cellular response to monosodium L-glutamate; and response to antibiotic. Localizes to the cytoplasm; nuclear membrane; and nuclear periphery. Human ortholog(s) of this gene implicated in adult-onset autosomal dominant demyelinating leukodystrophy. Orthologous to human LMNB1 (lamin B1); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: lamin-B1
Orthologs:
Homo sapiens (human) : LMNB1 (lamin B1)  HGNC  Alliance
Mus musculus (house mouse) : Lmnb1 (lamin B1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lmnb1 (lamin B1)
Pan paniscus (bonobo/pygmy chimpanzee) : LMNB1 (lamin B1)
Canis lupus familiaris (dog) : LMNB1 (lamin B1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lmnb1 (lamin B1)
Sus scrofa (pig) : LMNB1 (lamin B1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01851,785,111 - 51,822,264 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01850,979,862 - 51,018,232 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41852,470,605 - 52,508,022 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11852,516,112 - 52,553,517 (+)NCBI
Celera1848,320,757 - 48,358,598 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Lmnb1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620522
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.