Gene: Tsc1 (TSC complex subunit 1) Rattus norvegicus
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Symbol: Tsc1
Name: TSC complex subunit 1
Description: ENCODES a protein that exhibits GTPase activating protein binding; protein N-terminus binding; ATPase inhibitor activity (ortholog); INVOLVED IN adult locomotory behavior; cellular response to oxygen-glucose deprivation; negative regulation of cell proliferation; PARTICIPATES IN mTOR signaling pathway; insulin signaling pathway; ASSOCIATED WITH obesity; astrocytoma (ortholog); autism spectrum disorder (ortholog); FOUND IN cell projection; cytoskeleton; cytosol; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: hamartin; tuberous sclerosis 1; tuberous sclerosis 1 protein homolog
Orthologs:
Homo sapiens (human) : TSC1 (TSC complex subunit 1)  HGNC  Alliance
Mus musculus (house mouse) : Tsc1 (tuberous sclerosis 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tsc1 (TSC complex subunit 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TSC1 (TSC complex subunit 1)
Canis lupus familiaris (dog) : TSC1 (TSC complex subunit 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tsc1 (TSC complex subunit 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.037,219,955 - 7,269,063 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0312,570,765 - 12,619,753 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.437,645,313 - 7,672,944 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.137,645,612 - 7,673,244 (+)NCBI
Celera36,767,562 - 6,795,193 (+)NCBICelera
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tsc1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620124
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-10-09
Status: ACTIVE