Igbp1 (immunoglobulin binding protein 1)

Gene: Igbp1 (immunoglobulin binding protein 1) Rattus norvegicus

Analyze

Symbol:

Igbp1

Name:

immunoglobulin binding protein 1

RGD ID:

62011

Description:

Enables protein phosphatase 2A binding activity. Predicted to be involved in several processes, including negative regulation of stress-activated MAPK cascade; regulation of dephosphorylation; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of apoptotic signaling pathway. Predicted to be located in cytoplasm and microtubule. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome. Orthologous to several human genes including IGBP1 (immunoglobulin binding protein 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

alpha4 phosphoprotein; CD79a-binding protein 1; immunoglobulin (CD79A) binding protein 1; immunoglobulin-binding protein 1; protein phosphatase 2/4/6 regulatory subunit

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	IGBP1 (immunoglobulin binding protein 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Igbp1 (immunoglobulin (CD79A) binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Igbp1 (immunoglobulin binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	IGBP1 (immunoglobulin binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	IGBP1 (immunoglobulin binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Igbp1 (immunoglobulin binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	IGBP1 (immunoglobulin binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	IGBP1 (immunoglobulin binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Igbp1 (immunoglobulin binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	IGBP1C (IGBP1 family member C)	HGNC	Ensembl, OrthoDB, Panther
Homo sapiens (human):	FKBPL (FKBP prolyl isomerase like)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Igbp1 (immunoglobulin (CD79A) binding protein 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	IGBP1 (immunoglobulin binding protein 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	IGBP1C (IGBP1 family member C)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	igbp1 (immunoglobulin (CD79A) binding protein 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	TAP42	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Tap42	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ppfr-4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	igbp1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	69,622,925 - 69,645,167 (+)	NCBI		GRCr8
mRatBN7.2	X	65,582,832 - 65,605,078 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	65,582,821 - 65,606,049 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	67,066,253 - 67,088,494 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	70,566,639 - 70,588,880 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	68,127,540 - 68,149,782 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	70,322,764 - 70,345,005 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	70,322,755 - 70,345,005 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	71,194,717 - 71,216,957 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	88,490,498 - 88,507,054 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	88,566,669 - 88,580,484 (+)	NCBI
Celera	X	65,942,243 - 65,964,485 (+)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Breast Neoplasms (ISO)

corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

Lung Neoplasms (ISO)

Neoplastic Cell Transformation (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

1,2-dimethylhydrazine (ISO)

1-chloro-2,4-dinitrobenzene (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

acetamide (EXP)

ammonium chloride (EXP)

aristolochic acid A (ISO)

Aroclor 1254 (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

Brodifacoum (EXP)

carbamazepine (ISO)

CGP 52608 (ISO)

cisplatin (ISO)

cyclosporin A (ISO)

dicrotophos (ISO)

enzyme inhibitor (ISO)

ethyl methanesulfonate (ISO)

folic acid (ISO)

fulvestrant (ISO)

genistein (ISO)

gentamycin (EXP)

hydralazine (ISO)

ivermectin (ISO)

methyl methanesulfonate (ISO)

microcystin-LR (ISO)

N-nitrosodiethylamine (EXP)

ozone (ISO)

phenethyl caffeate (EXP)

sodium fluoride (ISO)

sunitinib (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

B cell activation (IEA)

negative regulation of apoptotic signaling pathway (ISO)

negative regulation of protein dephosphorylation (ISO)

negative regulation of stress-activated MAPK cascade (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

positive regulation of dephosphorylation (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

regulation of dephosphorylation (IBA)

regulation of microtubule-based movement (ISO)

response to interleukin-1 (ISO)

response to tumor necrosis factor (ISO)

Cellular Component

cytoplasm (ISO)

cytosol (IBA)

microtubule (ISO)

Molecular Function

enzyme binding (ISO)

mitogen-activated protein kinase kinase binding (ISO)

protein binding (ISO)

protein domain specific binding (ISO)

protein phosphatase 2A binding (IBA,IPI)

protein phosphatase regulator activity (ISO)

protein-containing complex binding (IPI)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
4.	Characterization of a novel, cytokine-inducible carboxypeptidase D isoform in haematopoietic tumour cells.	O'Malley PG, etal., Biochem J. 2005 Sep 15;390(Pt 3):665-73.
5.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
6.	GOA pipeline	RGD automated data pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
11.	Differential expression of elongation factor-2, alpha4 phosphoprotein and Cdc5-like protein in prolactin-dependent/independent rat lymphoid cells.	Too CK Mol Cell Endocrinol 1997 Aug 8;131(2):221-32.

Additional References at PubMed

PMID:9647778	PMID:9792806	PMID:11806752	PMID:15489334	PMID:15499020	PMID:17438131	PMID:18949047	PMID:20544796	PMID:28526910	PMID:33737606

Genomics

Comparative Map Data

Igbp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	69,622,925 - 69,645,167 (+)	NCBI		GRCr8
mRatBN7.2	X	65,582,832 - 65,605,078 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	65,582,821 - 65,606,049 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	67,066,253 - 67,088,494 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	70,566,639 - 70,588,880 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	68,127,540 - 68,149,782 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	70,322,764 - 70,345,005 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	70,322,755 - 70,345,005 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	71,194,717 - 71,216,957 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	88,490,498 - 88,507,054 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	88,566,669 - 88,580,484 (+)	NCBI
Celera	X	65,942,243 - 65,964,485 (+)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

IGBP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	70,133,447 - 70,166,324 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	70,133,447 - 70,166,324 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	69,353,297 - 69,386,174 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	69,270,043 - 69,302,899 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	69,136,338 - 69,169,192	NCBI
Celera	X	69,706,683 - 69,739,540 (+)	NCBI		Celera
Cytogenetic Map	X	q13.1	NCBI
HuRef	X	63,174,076 - 63,207,564 (+)	NCBI		HuRef
CHM1_1	X	69,246,939 - 69,279,788 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	68,566,802 - 68,599,681 (+)	NCBI		T2T-CHM13v2.0

Igbp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	99,537,897 - 99,559,731 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	99,537,897 - 99,559,731 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	100,494,291 - 100,516,125 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	100,494,291 - 100,516,125 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	97,689,630 - 97,711,464 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	96,697,064 - 96,718,720 (+)	NCBI		MGSCv36	mm8
Celera	X	87,420,356 - 87,442,287 (+)	NCBI		Celera
Cytogenetic Map	X	C3	NCBI
cM Map	X	43.72	NCBI

Igbp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955475	9,671,162 - 9,694,926 (+)	NCBI	ChiLan1.0	ChiLan1.0

IGBP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	69,810,161 - 69,843,192 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	69,813,728 - 69,846,794 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	59,401,426 - 59,434,363 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	69,460,736 - 69,493,616 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	69,460,734 - 69,493,616 (+)	Ensembl	panpan1.1		panPan2

IGBP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	54,558,515 - 54,612,029 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	54,547,446 - 54,613,171 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	45,384,171 - 45,437,674 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	55,524,457 - 55,577,975 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	55,513,867 - 55,579,130 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	53,493,501 - 53,547,031 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	54,824,297 - 54,877,823 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	54,751,460 - 54,804,992 (+)	NCBI		UU_Cfam_GSD_1.0

Igbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	47,530,398 - 47,557,161 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936762	1,292,572 - 1,319,145 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IGBP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	X	56,173,773 - 56,206,121 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	63,371,489 - 63,403,353 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IGBP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	59,970,740 - 60,008,066 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	59,971,234 - 60,008,047 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	1,827,501 - 1,859,929 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Igbp1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624903	71,212 - 94,470 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Igbp1
26 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	204
Count of miRNA genes:	141
Interacting mature miRNAs:	159
Transcripts:	ENSRNOT00000057900
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61430	Cia18	Collagen induced arthritis QTL 18	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	14843113	120568734	Rat
1598837	Memor13	Memory QTL 13	3.2		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	41052407	146860749	Rat
738035	Stresp1	Stress response QTL 1	4.96	0.000011	stress-related behavior trait (VT:0010451)	defensive burying - coping	X	41304447	112935181	Rat
70221	Bp56	Blood pressure QTL 56	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	X	57042141	65612192	Rat

Markers in Region

RH129961

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	65,604,760 - 65,604,978 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	70,344,688 - 70,344,905	NCBI	Rnor6.0
Rnor_5.0	X	71,216,640 - 71,216,857	UniSTS	Rnor5.0
RGSC_v3.4	X	88,506,737 - 88,506,954	UniSTS	RGSC3.4
Celera	X	65,964,168 - 65,964,385	UniSTS
Cytogenetic Map	X	q31	UniSTS

AW208785

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	65,604,709 - 65,604,825 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	70,344,637 - 70,344,752	NCBI	Rnor6.0
Rnor_5.0	X	71,216,589 - 71,216,704	UniSTS	Rnor5.0
RGSC_v3.4	X	88,506,686 - 88,506,801	UniSTS	RGSC3.4
Celera	X	65,964,117 - 65,964,232	UniSTS
Cytogenetic Map	X	q31	UniSTS

RH135891

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	65,582,856 - 65,583,025 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	70,322,789 - 70,322,957	NCBI	Rnor6.0
Rnor_5.0	X	71,194,742 - 71,194,910	UniSTS	Rnor5.0
Celera	X	65,942,268 - 65,942,436	UniSTS
Cytogenetic Map	X	q31	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	37	57	41	19	41	8	11	74	35	34	11	8
Low		6									6
Below cutoff											1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_031624	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC141377	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF000577	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC068202	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473966	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212697	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222671	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000057900 ⟹ ENSRNOP00000054708

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	65,582,821 - 65,606,049 (+)	Ensembl
Rnor_6.0 Ensembl	X	70,322,755 - 70,345,005 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000076176

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	X	70,330,198 - 70,344,747 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000076293

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	X	70,332,936 - 70,344,879 (+)	Ensembl

RefSeq Acc Id:

NM_031624 ⟹ NP_113812

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	69,622,925 - 69,645,167 (+)	NCBI
mRatBN7.2	X	65,582,832 - 65,605,078 (+)	NCBI
Rnor_6.0	X	70,322,764 - 70,345,005 (+)	NCBI
Rnor_5.0	X	71,194,717 - 71,216,957 (+)	NCBI
RGSC_v3.4	X	88,490,498 - 88,507,054 (+)	RGD
Celera	X	65,942,243 - 65,964,485 (+)	RGD

Sequence:

show sequence

TCTTTCCACAAGATGGCAGCGTCTGAAGAAGAGTTACTGCTGCCGCGGCTTCCGGAGCTCTTCG
AAACCAGCAAGAAACTTCTGGAGGAGTTGGAAGTAGCAACTGAACCCACCGGCTCCCGAACAAT
CCAGGATAAGGTGTCCAAAGGACTAGAACTCCTTGAGAAGGCTGCCGGAATGTTATCGCAGCTT
GATTTGTTCAGCCGAAATGAAGATTTGGAAGAGATTGCTTCTATCGACCTGAAGTACCTGATGG
TACCAGCGTTGCAAGGAGCTCTCACCATGAAACAAGTCAACCCCAGCAAGCGTCTAGATCATTT
GCAGCGGGCTCGAGAACACTTCATACATTTCTTAACTCAGTGTCATTGCTATCATGTGGCAGAG
TTTCAGCTACCCCAAACCAAGAATAACTCAGCTGAAAATAATACTGCTCGCTCCTCCATGGCCT
ATCCAAATCTCGTTGCTATGGCATCTCAAAGACAGGCTAAAATAGAGAGATACAAGCAGAAGAA
GGAGGTGGAGCATAGGTTGTCTGCACTGAAATCTGCTGTGGAAAGTGGTCAAGCAGATGATGAG
CGTGTTCGTGAATATTACCTCCTTCACCTTCGGAGGTGGATTGGTATCAGCTTAGAAGAGATTG
AGAGCATTGACCAGGAAATAAAGATCCTGAAAGACAAAGACTCTCCAAGAGAGGAATCAGCTTG
TCAGTCATCTCTTCCAGAGAAGCCTCCAATGAAACCCTTCATCCTCACTCGGAACAAGGCACAA
GCCAAAGTATTTGGAACTGGTTATCCCAGCCTGGCAACTATGACGGTGAGTGACTGGTATGAAC
AGCATCAGAAGTACGGAGCCTTACCAGATCGGGGAATAGCCAAGCCGCCATCAGCTGATTTTCA
AAGAGCAGCTCAGCAGCAGGAAGATCAAGAGCAAAAGGATGAAGAGAATGAGGAGAAAGCCTTG
CACAGGATGCGAGAGTGGGATGACTGGAAGGACACGCATCCCAGGGGCTATGGCAACCGGCAGA
ACATGGGCTAGTCATTCCAGAAGGCCAAAGGACAACGTGGTGCACACCTTCACACCAAGGACAA
CTTCAGGAGGGTGCAGTGAGGGCAGCCATGTGGAGTCTTGCATTGCATTTGATAGTGTCAAATA
ATTGCTTGTACCCTAGGTAATGACCAGTGAATTTTTGTTTGGCTTTATTAATCTCATCATGGTG
TATTCTGATTTCTTAAGCGGTCAGAAAAGAGCACCAAGAAATGGCTCTATATAATCAACGATAG
TATGAAGTAATTCTCTTAAAAAAAATAAAACCCCCCTATTATGTGGGCCTATGCACAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_113812	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD05364	(Get FASTA)	NCBI Sequence Viewer
	AAH68202	(Get FASTA)	NCBI Sequence Viewer
	EDL95938	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000054708
	ENSRNOP00000054708.3
	ENSRNOP00055043193
	ENSRNOP00060030776
	ENSRNOP00065021761
GenBank Protein	O08836	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_113812 ⟸ NM_031624

- UniProtKB:

O08836 (UniProtKB/Swiss-Prot), A6IQ75 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAASEEELLLPRLPELFETSKKLLEELEVATEPTGSRTIQDKVSKGLELLEKAAGMLSQLDLFS
RNEDLEEIASIDLKYLMVPALQGALTMKQVNPSKRLDHLQRAREHFIHFLTQCHCYHVAEFQLP
QTKNNSAENNTARSSMAYPNLVAMASQRQAKIERYKQKKEVEHRLSALKSAVESGQADDERVRE
YYLLHLRRWIGISLEEIESIDQEIKILKDKDSPREESACQSSLPEKPPMKPFILTRNKAQAKVF
GTGYPSLATMTVSDWYEQHQKYGALPDRGIAKPPSADFQRAAQQQEDQEQKDEENEEKALHRMR
EWDDWKDTHPRGYGNRQNMG

hide sequence

RefSeq Acc Id:

ENSRNOP00000054708 ⟸ ENSRNOT00000057900

Protein Domains

UIM

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O08836-F1-model_v2	AlphaFold	O08836	1-340	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701864

Promoter ID:

EPDNEW_R12388

Type:

multiple initiation site

Name:

Igbp1_1

Description:

immunoglobulin binding protein 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	X	70,322,765 - 70,322,825	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:62011	AgrOrtholog
BioCyc Gene	G2FUF-2133	BioCyc
Ensembl Genes	ENSRNOG00000026267	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOG00055030116	UniProtKB/Swiss-Prot
	ENSRNOG00060021539	UniProtKB/Swiss-Prot
	ENSRNOG00065016594	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000057900	ENTREZGENE
	ENSRNOT00000057900.5	UniProtKB/Swiss-Prot
	ENSRNOT00055052258	UniProtKB/Swiss-Prot
	ENSRNOT00060037310	UniProtKB/Swiss-Prot
	ENSRNOT00065027640	UniProtKB/Swiss-Prot
Gene3D-CATH	1.25.40.540	UniProtKB/Swiss-Prot
	6.10.250.1140	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TAP42-like family	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:6921265	IMAGE-MGC_LOAD
InterPro	TAP42/TAP46-like_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TAP46-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:58845	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:72768	IMAGE-MGC_LOAD
NCBI Gene	58845	ENTREZGENE
PANTHER	IMMUNOGLOBULIN-BINDING PROTEIN 1	UniProtKB/Swiss-Prot
	IMMUNOGLOBULIN-BINDING PROTEIN 1	UniProtKB/TrEMBL
	IMMUNOGLOBULIN-BINDING PROTEIN 1	UniProtKB/TrEMBL
	PTHR10933	UniProtKB/Swiss-Prot
Pfam	TAP42	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Igbp1	PhenoGen
RatGTEx	ENSRNOG00000026267	RatGTEx
	ENSRNOG00055030116	RatGTEx
	ENSRNOG00060021539	RatGTEx
	ENSRNOG00065016594	RatGTEx
TIGR	TC229471
UniProt	A6IQ75	ENTREZGENE, UniProtKB/TrEMBL
	IGBP1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-02-01	Igbp1	immunoglobulin binding protein 1	Igbp1	immunoglobulin (CD79A) binding protein 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Igbp1	immunoglobulin (CD79A) binding protein 1		immunoglobulin binding protein 1	Name updated	1299863	APPROVED
2002-06-10	Igbp1	immunoglobulin binding protein 1			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_regulation	expression is responsive to prolactin	61637

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM