Csnk2b (casein kinase 2 beta) - Rat Genome Database

Name: Csnk2b
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Csnk2b (casein kinase 2 beta) Rattus norvegicus

Analyze

Symbol:

Csnk2b

Name:

casein kinase 2 beta

RGD ID:

619978

Description:

Enables ribonucleoprotein complex binding activity. Involved in liver regeneration and response to testosterone. Located in cell projection and nuclear matrix. Part of chromatin. Biomarker of myocardial infarction. Orthologous to human CSNK2B (casein kinase 2 beta); PARTICIPATES IN E-cadherin signaling pathway; mitochondrial autophagy pathway; nuclear factor kappa B signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

casein kinase 2, beta polypeptide; casein kinase 2, beta subunit; casein kinase II beta subunit; casein kinase II subunit beta; chimera Csnk2b-Ly6g5b splicing isoform 2050; chimera Csnk2b-Ly6g5b splicing isoform 2275; chimera Csnk2b-Ly6g5b splicing isoform 2531; chimera Csnk2b-Ly6g5b splicing isoform 901; CK II beta; Ck2; Csnk2b splicing isoform 280; Csnk2b splicing isoform 662; Csnk2b-Ly6g5b; phosvitin

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CSNK2B (casein kinase 2 beta)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Csnk2b (casein kinase 2, beta polypeptide)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Csnk2b (casein kinase 2 beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CSNK2B (casein kinase 2 beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CSNK2B (casein kinase 2 beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Csnk2b (casein kinase 2 beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CSNK2B (casein kinase 2 beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CSNK2B (casein kinase 2 beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Csnk2b (casein kinase 2 beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CHRM3 (cholinergic receptor muscarinic 3)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	CSNK2B (casein kinase 2 beta)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Csnk2b (casein kinase 2, beta polypeptide)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	csnk2b (casein kinase 2, beta polypeptide)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CkIIbeta	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	kin-10	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	CKB2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	csnk2b	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	3,704,833 - 3,709,999 (+)	NCBI		GRCr8
mRatBN7.2	20	3,700,363 - 3,705,331 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	3,698,733 - 3,707,133 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	4,399,893 - 4,404,317 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	3,761,951 - 3,766,375 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	4,299,839 - 4,304,262 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	5,108,692 - 5,113,675 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	5,106,890 - 5,113,112 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	7,181,951 - 7,186,861 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	3,764,565 - 3,768,985 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	3,764,954 - 3,769,209 (+)	NCBI
Celera	20	4,320,311 - 4,324,731 (-)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

adult T-cell leukemia/lymphoma (ISO)

autism spectrum disorder (ISO)

autosomal dominant intellectual developmental disorder (ISO)

enophthalmos (ISO)

epilepsy (ISO)

genetic disease (ISO)

Hypoglossal Nerve Injuries (IEP)

intellectual disability (ISO)

leiomyoma (ISO)

Malocclusion, Angle Class III (ISO)

megacolon (ISO)

myocardial infarction (IEP)

Neurodevelopmental Disorders (ISO)

Oxygen-Induced Retinopathy (ISO)

POIRIER-BIENVENU NEURODEVELOPMENTAL SYNDROME (ISO)

proteasome-associated autoinflammatory syndrome 1 (ISO)

Skin Neoplasms (ISO)

squamous cell carcinoma (ISO)

syndactyly (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (ISO)

4,4'-diaminodiphenylmethane (ISO)

5-aza-2'-deoxycytidine (ISO)

5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (EXP)

6-propyl-2-thiouracil (EXP)

all-trans-retinoic acid (ISO)

amiodarone (EXP)

ammonium chloride (EXP)

arsenite(3-) (ISO)

ATP (ISO)

atrazine (ISO)

benzbromarone (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bromobenzene (EXP)

cadmium dichloride (EXP)

capsaicin (ISO)

chlorpyrifos (ISO)

choline (ISO)

chromium(6+) (ISO)

chrysin 5,7-dimethyl ether (EXP)

cisplatin (ISO)

clofibrate (EXP)

crocidolite asbestos (ISO)

cycloheximide (ISO)

dibutyl phthalate (EXP,ISO)

dicrotophos (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

emodin (ISO)

flutamide (EXP)

folic acid (ISO)

FR900359 (ISO)

genistein (EXP)

gentamycin (EXP)

ivermectin (ISO)

L-ethionine (EXP)

L-methionine (ISO)

lead(0) (ISO)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

N-nitrosodiethylamine (EXP)

omeprazole (EXP)

paracetamol (ISO)

phenethyl isothiocyanate (EXP)

pirinixic acid (EXP)

Propiverine (EXP)

pyrogallol (ISO)

quercetin (ISO)

rotenone (EXP)

selenium atom (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

thioacetamide (EXP)

triptonide (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adiponectin-activated signaling pathway (IEA,ISO)

endothelial tube morphogenesis (IEA,ISO)

liver regeneration (IEP)

negative regulation of blood vessel endothelial cell migration (IEA,ISO)

negative regulation of proteasomal ubiquitin-dependent protein catabolic process (ISO)

negative regulation of viral life cycle (IEA,ISO)

positive regulation of activin receptor signaling pathway (IEA,ISO)

positive regulation of SMAD protein signal transduction (IEA,ISO)

regulation of transcription by RNA polymerase III (IEA)

response to testosterone (IEP)

symbiont-mediated disruption of host cell PML body (IEA,ISO)

Wnt signaling pathway (IEA)

Cellular Component

cell projection (IDA)

chromatin (IDA,IEA,ISO)

cytoplasm (IBA,IEA,ISO)

nuclear matrix (IDA)

nucleus (ISO)

PcG protein complex (IEA,ISO,ISS)

plasma membrane (IEA,ISO)

PML body (IEA,ISO)

protein kinase CK2 complex (IBA,IEA,ISO)

UTP-C complex (IEA)

Molecular Function

chromatin binding (IEA,ISO)

identical protein binding (IEA,ISO)

metal ion binding (IEA)

protein binding (ISO)

protein domain specific binding (IEA,ISO)

protein kinase regulator activity (IBA,IEA)

protein serine/threonine kinase activity (IEA,ISO)

protein-macromolecule adaptor activity (IEA,ISO)

ribonucleoprotein complex binding (IDA)

RNA polymerase II-specific DNA-binding transcription factor binding (IEA,ISO)

signaling receptor binding (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

E-cadherin signaling pathway (ISO)

measles pathway (IEA)

mitochondrial autophagy pathway (ISO)

nuclear factor kappa B signaling pathway (ISO)

ribosome biogenesis pathway (IEA)

Wnt signaling pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Cloning of cDNAs encoding the alpha and beta subunits of rat casein kinase 2 (CK-2): investigation of molecular regulation of CK-2 by androgens in rat ventral prostate.	Ahmed K, etal., Cell Mol Biol Res 1993;39(5):451-62.
2.	Differential localization of alpha' and beta subunits of protein kinase CK2 during rat spermatogenesis.	Alvarado-Diaz CP, etal., Cell Tissue Res. 2009 Oct;338(1):139-49. doi: 10.1007/s00441-009-0847-1. Epub 2009 Aug 27.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Morphological changes and expression of protein kinase CK2 beta subunit in the microglia after hypoglossal nerve transection.	Gesase AP and Kiyama H, J Neurocytol. 2000 Jan;29(1):61-6.
5.	Protein kinase CK2 modulates synaptic plasticity by modification of synaptic NMDA receptors in the hippocampus.	Kimura R and Matsuki N, J Physiol. 2008 Jul 1;586(13):3195-206. doi: 10.1113/jphysiol.2008.151894. Epub 2008 May 15.
6.	Expression of protein kinase CK2 in astroglial cells of normal and neovascularized retina.	Kramerov AA, etal., Am J Pathol. 2006 May;168(5):1722-36.
7.	Role of autophosphorylation in regulation of protein kinase CK2 from rat neuronal chromatin.	Kulikova OG and Reikhardt BA, Biochemistry (Mosc). 1998 Dec;63(12):1400-6.
8.	Protein kinase CK2: signaling and tumorigenesis in the mammary gland.	Landesman-Bollag E, etal., Mol Cell Biochem 2001 Nov;227(1-2):153-65.
9.	Quantitative proteome profiling of human myoma and myometrium tissue reveals kinase expression signatures with potential for therapeutic intervention.	Lemeer S, etal., Proteomics. 2015 Jan;15(2-3):356-64. doi: 10.1002/pmic.201400213. Epub 2014 Dec 17.
10.	HIV-1 Rev transactivator: a beta-subunit directed substrate and effector of protein kinase CK2.	Meggio F, etal., Mol Cell Biochem 2001 Nov;227(1-2):145-51.
11.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
12.	Changes in the activity of nuclear protein kinase CK2 during rat liver regeneration.	Pancetti F, etal., Biochem Biophys Res Commun. 1996 Jan 5;218(1):35-9.
13.	Heterogeneous nuclear ribonucleoprotein A2 interacts with protein kinase CK2.	Pancetti F, etal., Biochem Biophys Res Commun. 1999 Jun 24;260(1):17-22.
14.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
15.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
16.	GOA pipeline	RGD automated data pipeline
17.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
18.	Comprehensive gene review and curation	RGD comprehensive gene curation
19.	The tight association of protein kinase CK2 with plasma membranes is mediated by a specific domain of its regulatory beta-subunit.	Sarrouilhe D, etal., Biochim Biophys Acta. 1998 Jun 22;1403(2):199-210.
20.	Selective removal of mitochondria via mitophagy: distinct pathways for different mitochondrial stresses.	Wei H, etal., Biochim Biophys Acta. 2015 Oct;1853(10 Pt B):2784-90. doi: 10.1016/j.bbamcr.2015.03.013. Epub 2015 Apr 1.
21.	Differential gene expression in infarct scar and viable myocardium from rat heart following coronary ligation.	Xu YJ, etal., J Cell Mol Med. 2004 Jan-Mar;8(1):85-92.
22.	Consequences of CK2 signaling to the nuclear matrix.	Yu S, etal., Mol Cell Biochem 2001 Nov;227(1-2):67-71.
23.	Mechanism of protein kinase CK2 association with nuclear matrix: role of disulfide bond formation.	Zhang P, etal., J Cell Biochem. 1998 May 1;69(2):211-20.

Additional References at PubMed

PMID:8083223	PMID:8206911	PMID:10094392	PMID:10398585	PMID:11744621	PMID:11984006	PMID:12477932	PMID:12511551	PMID:14645218	PMID:14667819	PMID:15060004	PMID:15297462
PMID:15537897	PMID:15723517	PMID:15882073	PMID:15897466	PMID:16335525	PMID:17520485	PMID:17553997	PMID:18089804	PMID:18278803	PMID:19064667	PMID:19233263	PMID:19324893
PMID:19460754	PMID:19542537	PMID:19592636	PMID:20458337	PMID:20493168	PMID:20869595	PMID:21187092	PMID:21282530	PMID:21431367	PMID:21630459	PMID:21988832	PMID:22206666
PMID:22447044	PMID:23521802	PMID:23553788	PMID:23555304	PMID:25519132	PMID:25931508	PMID:25950943	PMID:26362340	PMID:27276705	PMID:27782092	PMID:27851782	PMID:29476059
PMID:31904090	PMID:34884938	PMID:34948351

Genomics

Comparative Map Data

Csnk2b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	3,704,833 - 3,709,999 (+)	NCBI		GRCr8
mRatBN7.2	20	3,700,363 - 3,705,331 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	3,698,733 - 3,707,133 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	4,399,893 - 4,404,317 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	3,761,951 - 3,766,375 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	4,299,839 - 4,304,262 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	5,108,692 - 5,113,675 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	5,106,890 - 5,113,112 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	7,181,951 - 7,186,861 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	3,764,565 - 3,768,985 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	3,764,954 - 3,769,209 (+)	NCBI
Celera	20	4,320,311 - 4,324,731 (-)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

CSNK2B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	31,666,080 - 31,670,067 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	31,665,227 - 31,670,343 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	31,633,857 - 31,637,844 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	31,741,636 - 31,745,822 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	31,741,635 - 31,745,822	NCBI
Celera	6	33,231,878 - 33,236,064 (+)	NCBI		Celera
Cytogenetic Map	6	p21.33	NCBI
HuRef	6	31,419,882 - 31,424,068 (+)	NCBI		HuRef
CHM1_1	6	31,635,793 - 31,639,979 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	31,519,114 - 31,523,101 (+)	NCBI		T2T-CHM13v2.0

Csnk2b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	35,335,171 - 35,341,029 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	35,335,172 - 35,341,029 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	35,116,195 - 35,122,053 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	35,116,196 - 35,122,053 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	35,253,140 - 35,258,392 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	34,724,251 - 34,729,503 (-)	NCBI		MGSCv36	mm8
Celera	17	38,213,147 - 38,218,397 (-)	NCBI		Celera
Cytogenetic Map	17	B1	NCBI
cM Map	17	18.59	NCBI

Csnk2b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	210,838 - 219,694 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	210,541 - 215,725 (+)	NCBI	ChiLan1.0	ChiLan1.0

CSNK2B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	46,143,115 - 46,147,114 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	42,104,623 - 42,108,622 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	31,327,250 - 31,331,250 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	32,216,283 - 32,221,131 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

CSNK2B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	1,149,467 - 1,154,417 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	1,149,548 - 1,154,418 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	1,285,676 - 1,290,594 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	1,294,469 - 1,299,387 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	1,294,519 - 1,301,941 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	1,153,768 - 1,158,617 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	1,221,041 - 1,225,991 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	1,288,118 - 1,293,071 (+)	NCBI		UU_Cfam_GSD_1.0

Csnk2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	35,698,801 - 35,703,748 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936727	1,857,596 - 1,862,002 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936727	1,857,596 - 1,862,551 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CSNK2B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	23,786,805 - 23,787,808 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1 Ensembl	7	23,780,362 - 23,788,678 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	23,781,194 - 23,787,914 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	27,464,062 - 27,471,599 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CSNK2B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	40,354,520 - 40,359,136 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	40,352,367 - 40,358,401 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	31,577,195 - 31,581,146 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Csnk2b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624754	24,533,134 - 24,538,233 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Csnk2b
64 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	59
Count of miRNA genes:	56
Interacting mature miRNAs:	58
Transcripts:	ENSRNOT00000001123
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354642	Despr15	Despair related QTL 15		0.0027	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	20	1	24159021	Rat
1600382	Edcs3	Endometrial carcinoma susceptibility QTL3	3.5	0.003	uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	20	1	25159026	Rat
2317851	Alcrsp22	Alcohol response QTL 22	3.2	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27339237	Rat
1641893	Alcrsp7	Alcohol response QTL 7			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27339237	Rat
8694189	Bw153	Body weight QTL 153	3.13	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	20	1	29191651	Rat
9590275	Scort15	Serum corticosterone level QTL 15	3.48	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	29191651	Rat
7411650	Foco23	Food consumption QTL 23	20.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	29191651	Rat
9590109	Sffal8	Serum free fatty acids level QTL 8	5.32	0.01	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	20	1	29191651	Rat
9589155	Insul32	Insulin level QTL 32	6.38	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	29191651	Rat
6893685	Bw111	Body weight QTL 111	2.7	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	20	1	32578807	Rat
7411668	Foco32	Food consumption QTL 32	8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	36600972	Rat
9590252	Scort12	Serum corticosterone level QTL 12	20.46	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	36600972	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	1527842	46527842	Rat
2306850	Pia40	Pristane induced arthritis QTL 40		0.0001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	1527959	5304575	Rat
1641915	Colcr9	Colorectal carcinoma resistance QTL 9	2.97	0.0024	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	20	1530655	46530655	Rat
1598816	Memor12	Memory QTL 12	2.4		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	20	2606836	47606836	Rat
61448	Ciaa1	CIA Autoantibody QTL 1	30	0.001	blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	20	2646395	4597031	Rat
61472	Aia1	Adjuvant induced arthritis QTL 1	18	0.001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	2646395	4597031	Rat
2317057	Aia27	Adjuvant induced arthritis QTL 27	2.83		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	20	2892597	26381954	Rat
1300152	Bp195	Blood pressure QTL 195	3.46		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	20	3621649	9243559	Rat
1331772	Cdexp2	CD45RC expression in CD8 T cells QTL 2	5.7		CD8-positive T cell quantity (VT:0008077)	blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)	20	3621649	10078919	Rat
737973	Pia21	Pristane induced arthritis QTL 21	4.8		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	3621656	4606812	Rat
61432	Cia1	Collagen induced arthritis QTL 1			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	3621656	14101050	Rat

Markers in Region

D20Yum50

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	3,702,594 - 3,702,749 (-)	MAPPER	mRatBN7.2
Rnor_6.0	20	5,111,274 - 5,111,428	NCBI	Rnor6.0
Rnor_5.0	20	7,184,533 - 7,184,687	UniSTS	Rnor5.0
RGSC_v3.4	20	3,766,249 - 3,766,403	UniSTS	RGSC3.4
Celera	20	4,322,893 - 4,323,047	UniSTS
Cytogenetic Map	20	p12	UniSTS

RH129972

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	3,705,110 - 3,705,300 (-)	MAPPER	mRatBN7.2
Rnor_6.0	20	5,108,723 - 5,108,912	NCBI	Rnor6.0
Rnor_5.0	20	7,181,982 - 7,182,171	UniSTS	Rnor5.0
RGSC_v3.4	20	3,768,765 - 3,768,954	UniSTS	RGSC3.4
Celera	20	4,320,342 - 4,320,531	UniSTS
Cytogenetic Map	20	p12	UniSTS

RH137048

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	3,705,115 - 3,705,301 (-)	MAPPER	mRatBN7.2
Rnor_6.0	20	5,108,722 - 5,108,907	NCBI	Rnor6.0
Rnor_5.0	20	7,181,981 - 7,182,166	UniSTS	Rnor5.0
RGSC_v3.4	20	3,768,770 - 3,768,955	UniSTS	RGSC3.4
Celera	20	4,320,341 - 4,320,526	UniSTS
RH 3.4 Map	20	52.22	UniSTS
Cytogenetic Map	20	p12	UniSTS

MARC_3347-3348:991937077:1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	3,704,062 - 3,705,128 (-)	MAPPER	mRatBN7.2
Rnor_6.0	20	5,108,895 - 5,109,960	NCBI	Rnor6.0
Rnor_5.0	20	7,182,154 - 7,183,219	UniSTS	Rnor5.0
RGSC_v3.4	20	3,767,717 - 3,768,782	UniSTS	RGSC3.4
Celera	20	4,320,514 - 4,321,579	UniSTS
Cytogenetic Map	20	p12	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	8	11	74	35	41	11	8
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001035238	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_031021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006256081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC094348	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC078807	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BX883045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB743000	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB790784	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474121	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EV778558	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ209726	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212674	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ214437	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ224491	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HE864425	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HE864426	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HE864431	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HE864432	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HE864433	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HE864434	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000001123 ⟹ ENSRNOP00000001123

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	3,700,991 - 3,705,344 (+)	Ensembl
Rnor_6.0 Ensembl	20	5,108,695 - 5,112,984 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000076528 ⟹ ENSRNOP00000068429

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	3,698,733 - 3,707,133 (+)	Ensembl
Rnor_6.0 Ensembl	20	5,108,695 - 5,113,112 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000076597 ⟹ ENSRNOP00000068454

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	3,700,991 - 3,705,327 (+)	Ensembl
Rnor_6.0 Ensembl	20	5,109,462 - 5,110,191 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000076983 ⟹ ENSRNOP00000068085

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	20	5,108,692 - 5,112,872 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000092222 ⟹ ENSRNOP00000075275

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	3,700,991 - 3,705,016 (+)	Ensembl
Rnor_6.0 Ensembl	20	5,106,890 - 5,112,258 (-)	Ensembl

RefSeq Acc Id:

NM_001035238 ⟹ NP_001030315

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	3,705,579 - 3,709,999 (+)	NCBI
mRatBN7.2	20	3,700,911 - 3,705,331 (+)	NCBI
Rnor_6.0	20	5,108,692 - 5,113,112 (-)	NCBI
Rnor_5.0	20	7,181,951 - 7,186,861 (-)	NCBI
RGSC_v3.4	20	3,764,565 - 3,768,985 (+)	RGD
Celera	20	4,320,311 - 4,324,731 (-)	RGD

Sequence:

show sequence

GTTTGCCTTCCCTTCATTTCGTCAGTTTCTCTCTCCTGACGGGACTACATCTCCCGGCGTCCAC
GGAGCGGACATAAAGATGAGTAGCTCTGAGGAGGTGTCCTGGATTTCCTGGTTCTGTGGGCTCC
GTGGTAATGAATTCTTCTGTGAGGTGGATGAAGACTACATCCAGGACAAATTTAATCTTACTGG
ACTCAATGAGCAGGTGCCTCACTATCGACAAGCCCTAGACATGATCTTGGACCTGGAACCTGAT
GAAGAGCTGGAAGACAACCCCAACCAGAGTGACTTGATTGAGCAGGCGGCCGAGATGCTCTATG
GGTTGATCCACGCCCGCTACATCCTCACCAACCGGGGCATTGCACAAATGTTGGAAAAGTACCA
GCAAGGAGACTTTGGCTACTGTCCTCGAGTATACTGTGAGAACCAGCCGATGCTTCCCATCGGC
CTTTCGGACATCCCAGGAGAGGCCATGGTGAAGCTCTACTGCCCCAAGTGCATGGACGTGTACA
CACCCAAGTCCTCTAGGCACCACCACACGGATGGCGCATACTTCGGCACTGGTTTCCCTCACAT
GCTCTTCATGGTGCATCCCGAGTACCGGCCCAAGCGGCCGGCCAACCAGTTTGTGCCCAGGCTC
TACGGTTTCAAGATCCATCCAATGGCCTACCAGCTGCAGCTCCAAGCCGCCAGCAACTTCAAGA
GCCCAGTCAAGACGATTCGCTGAGTGCCCTCCCACCTCCTCTGCCTGTGACACCACCGTCCCTC
CGCTGCCACCCTTTCAGGAAGTCTATGGTTTTTAGTTTAAATTAAAGGAATTGTTACTGTGGTG
GGGATATGAAATAAAGGAAGAAAAGGCTATGA

hide sequence

RefSeq Acc Id:

NM_031021 ⟹ NP_112283

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	3,705,723 - 3,709,999 (+)	NCBI
mRatBN7.2	20	3,701,055 - 3,705,331 (+)	NCBI
Rnor_6.0	20	5,108,692 - 5,112,968 (-)	NCBI
Rnor_5.0	20	7,181,951 - 7,186,861 (-)	NCBI
RGSC_v3.4	20	3,764,565 - 3,768,985 (+)	RGD
Celera	20	4,320,311 - 4,324,587 (-)	NCBI

Sequence:

show sequence

CCCCCCCTCCCCACTTCGTCTGCCGCGGCCGGGTCGGCTTTTTGCGCTGTAGCGGTCTCTGCCG
TTCCTTGGAAGCACAGCTCCCCTTCCCCGCCCCAGTCCCAGTCCCCGTCCGGCCGCGGACATAA
AGATGAGTAGCTCTGAGGAGGTGTCCTGGATTTCCTGGTTCTGTGGGCTCCGTGGTAATGAATT
CTTCTGTGAGGTGGATGAAGACTACATCCAGGACAAATTTAATCTTACTGGACTCAATGAGCAG
GTGCCTCACTATCGACAAGCCCTAGACATGATCTTGGACCTGGAACCTGATGAAGAGCTGGAAG
ACAACCCCAACCAGAGTGACTTGATTGAGCAGGCGGCCGAGATGCTCTATGGGTTGATCCACGC
CCGCTACATCCTCACCAACCGGGGCATTGCACAAATGTTGGAAAAGTACCAGCAAGGAGACTTT
GGCTACTGTCCTCGAGTATACTGTGAGAACCAGCCGATGCTTCCCATCGGCCTTTCGGACATCC
CAGGAGAGGCCATGGTGAAGCTCTACTGCCCCAAGTGCATGGACGTGTACACACCCAAGTCCTC
TAGGCACCACCACACGGATGGCGCATACTTCGGCACTGGTTTCCCTCACATGCTCTTCATGGTG
CATCCCGAGTACCGGCCCAAGCGGCCGGCCAACCAGTTTGTGCCCAGGCTCTACGGTTTCAAGA
TCCATCCAATGGCCTACCAGCTGCAGCTCCAAGCCGCCAGCAACTTCAAGAGCCCAGTCAAGAC
GATTCGCTGAGTGCCCTCCCACCTCCTCTGCCTGTGACACCACCGTCCCTCCGCTGCCACCCTT
TCAGGAAGTCTATGGTTTTTAGTTTAAATTAAAGGAATTGTTACTGTGGTGGGGATATGAAATA
AAGGAAGAAAAGGCTATGA

hide sequence

RefSeq Acc Id:

XM_006256081 ⟹ XP_006256143

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	3,704,833 - 3,709,996 (+)	NCBI
mRatBN7.2	20	3,700,363 - 3,705,331 (+)	NCBI
Rnor_6.0	20	5,108,692 - 5,113,675 (-)	NCBI
Rnor_5.0	20	7,181,951 - 7,186,861 (-)	NCBI

Sequence:

show sequence

GAGCTGTGAGATGAAGTAACATCACGGCACCCCTCACCACTACTCTGAGCAGGGTTTGAAGAAC
AGTTAGGGTCCGCAGCAGGACGCTCCATCAAGCTCTGAGGAAATGGAGAAGTACAAAGGGACGA
GCGGCAGAATGGCTGGCCCCACCTCAGCGGACATAAAGATGAGTAGCTCTGAGGAGGTGTCCTG
GATTTCCTGGTTCTGTGGGCTCCGTGGTAATGAATTCTTCTGTGAGGTGGATGAAGACTACATC
CAGGACAAATTTAATCTTACTGGACTCAATGAGCAGGTGCCTCACTATCGACAAGCCCTAGACA
TGATCTTGGACCTGGAACCTGATGAAGAGCTGGAAGACAACCCCAACCAGAGTGACTTGATTGA
GCAGGCGGCCGAGATGCTCTATGGGTTGATCCACGCCCGCTACATCCTCACCAACCGGGGCATT
GCACAAATGTTGGAAAAGTACCAGCAAGGAGACTTTGGCTACTGTCCTCGAGTATACTGTGAGA
ACCAGCCGATGCTTCCCATCGGCCTTTCGGACATCCCAGGAGAGGCCATGGTGAAGCTCTACTG
CCCCAAGTGCATGGACGTGTACACACCCAAGTCCTCTAGGCACCACCACACGGATGGCGCATAC
TTCGGCACTGGTTTCCCTCACATGCTCTTCATGGTGCATCCCGAGTACCGGCCCAAGCGGCCGG
CCAACCAGTTTGTGCCCAGGCTCTACGGTTTCAAGATCCATCCAATGGCCTACCAGCTGCAGCT
CCAAGCCGCCAGCAACTTCAAGAGCCCAGTCAAGACGATTCGCTGAGTGCCCTCCCACCTCCTC
TGCCTGTGACACCACCGTCCCTCCGCTGCCACCCTTTCAGGAAGTCTATGGTTTTTAGTTTAAA
TTAAAGGAATTGTTACTGTGGTGGGGATATGAAATAAAGGAAGAAAAGGCTATGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001030315	(Get FASTA)	NCBI Sequence Viewer
	NP_112283	(Get FASTA)	NCBI Sequence Viewer
	XP_006256143	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH78807	(Get FASTA)	NCBI Sequence Viewer
	CAE83994	(Get FASTA)	NCBI Sequence Viewer
	CCI79662	(Get FASTA)	NCBI Sequence Viewer
	CCI79663	(Get FASTA)	NCBI Sequence Viewer
	CCI79668	(Get FASTA)	NCBI Sequence Viewer
	CCI79669	(Get FASTA)	NCBI Sequence Viewer
	CCI79670	(Get FASTA)	NCBI Sequence Viewer
	CCI79671	(Get FASTA)	NCBI Sequence Viewer
	EDL83521	(Get FASTA)	NCBI Sequence Viewer
	EDL83522	(Get FASTA)	NCBI Sequence Viewer
	EDL83523	(Get FASTA)	NCBI Sequence Viewer
	EDL83524	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000001123.4
	ENSRNOP00000068429
	ENSRNOP00000068429.2
	ENSRNOP00000068454.2
	ENSRNOP00000075275.2
GenBank Protein	P67874	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001030315 ⟸ NM_001035238

- UniProtKB:

P67874 (UniProtKB/Swiss-Prot), Q68G11 (UniProtKB/TrEMBL), N0E459 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELED
NPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIP
GEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKI
HPMAYQLQLQAASNFKSPVKTIR

hide sequence

RefSeq Acc Id:

NP_112283 ⟸ NM_031021

- UniProtKB:

P67874 (UniProtKB/Swiss-Prot), Q68G11 (UniProtKB/TrEMBL), N0E459 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELED
NPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIP
GEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKI
HPMAYQLQLQAASNFKSPVKTIR

hide sequence

RefSeq Acc Id:	XP_006256143 ⟸ XM_006256081
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2UP98 (UniProtKB/TrEMBL), A6KTU1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEKYKGTSGRMAGPTSADIKMSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVP HYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGY CPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHP EYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR hide sequence

RefSeq Acc Id:

ENSRNOP00000075275 ⟸ ENSRNOT00000092222

RefSeq Acc Id:

ENSRNOP00000068085 ⟸ ENSRNOT00000076983

RefSeq Acc Id:

ENSRNOP00000001123 ⟸ ENSRNOT00000001123

RefSeq Acc Id:

ENSRNOP00000068454 ⟸ ENSRNOT00000076597

RefSeq Acc Id:

ENSRNOP00000068429 ⟸ ENSRNOT00000076528

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P67874-F1-model_v2	AlphaFold	P67874	1-215	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701391

Promoter ID:

EPDNEW_R11915

Type:

initiation region

Name:

Csnk2b_1

Description:

casein kinase 2 beta

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	5,112,981 - 5,113,041	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:619978	AgrOrtholog
BioCyc Gene	G2FUF-4646	BioCyc
Ensembl Genes	ENSRNOG00000000847	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000001123.8	UniProtKB/TrEMBL
	ENSRNOT00000076528.2	UniProtKB/TrEMBL
	ENSRNOT00000076597.2	UniProtKB/TrEMBL
	ENSRNOT00000092222.2	UniProtKB/TrEMBL
Gene3D-CATH	1.10.1820.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	2.20.25.20	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7133064	IMAGE-MGC_LOAD
InterPro	Casein_kin_II_reg-sub_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Casein_kinase_II_beta-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Casein_kinase_II_reg-sub	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:81650	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:93390	IMAGE-MGC_LOAD
NCBI Gene	81650	ENTREZGENE
PANTHER	CASEIN KINASE II SUBUNIT BETA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR11740	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	CK_II_beta	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Csnk2b	PhenoGen
PRINTS	CASNKINASEII	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	CK2_BETA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000000847	RatGTEx
SMART	CK_II_beta	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF57798	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A096MKB7_RAT	UniProtKB/TrEMBL
	A0A0G2KA61_RAT	UniProtKB/TrEMBL
	A0A8L2PYP5_RAT	UniProtKB/TrEMBL
	A0A8L2UP98	ENTREZGENE, UniProtKB/TrEMBL
	A6KTU1	ENTREZGENE, UniProtKB/TrEMBL
	A6KTU4_RAT	UniProtKB/TrEMBL
	CSK2B_RAT	UniProtKB/Swiss-Prot
	N0E459	ENTREZGENE, UniProtKB/TrEMBL
	N0E631_RAT	UniProtKB/TrEMBL
	P67874	ENTREZGENE
	Q68G11	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	P07312	UniProtKB/Swiss-Prot
	P13862	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-01-27	Csnk2b	casein kinase 2 beta	Csnk2b	casein kinase 2, beta polypeptide	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-04-20	Csnk2b	casein kinase 2, beta polypeptide	Csnk2b	casein kinase 2, beta subunit	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	Csnk2b	casein kinase 2, beta subunit		casein kinase II beta subunit	Name updated	1299863	APPROVED
2002-08-07	Csnk2b	casein kinase II beta subunit			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_disease	increased expression is detected in carcinogen-induced breast tumors	727632
gene_regulation	properties are modulated by Rev protein	727694

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)