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Gene: Smc1a (structural maintenance of chromosomes 1A) Rattus norvegicus
Symbol: Smc1a
Name: structural maintenance of chromosomes 1A
Description: Predicted to have chromatin binding activity; mediator complex binding activity; and protein heterodimerization activity. Involved in meiotic cell cycle. Predicted to localize to several cellular components, including the chromosome; mitotic spindle pole; and nuclear lumen. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 2. Orthologous to human SMC1A (structural maintenance of chromosomes 1A); PARTICIPATES IN cell cycle pathway, mitotic; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,3-dinitrobenzene; 17alpha-ethynylestradiol.
Type: protein-coding
Also known as: DXhXs423e; KIAA0178; SB1.8; segregation of mitotic chromosomes-like 1; SMC (segregation of mitotic chromosomes 1)-like 1; SMC (segregation of mitotic chromosomes 1)-like 1 (yeast) ; SMC protein 1A; SMC-1A; SMC-like 1; SMC-like 1 (yeast) ; SMC-protein; Smc1l1; structural maintenance of chromosomes 1 like 1; structural maintenance of chromosomes 1 like 1 (S. cerevisiae); structural maintenance of chromosomes protein 1A
Homo sapiens (human) : SMC1A (structural maintenance of chromosomes 1A)  HGNC  Alliance
Mus musculus (house mouse) : Smc1a (structural maintenance of chromosomes 1A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smc1a (structural maintenance of chromosomes 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : SMC1A (structural maintenance of chromosomes 1A)
Canis lupus familiaris (dog) : SMC1A (structural maintenance of chromosomes 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smc1a (structural maintenance of chromosomes 1A)
Sus scrofa (pig) : SMC1A (structural maintenance of chromosomes 1A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X21,710,976 - 21,755,708 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X21,691,592 - 21,736,383 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X41,503,393 - 41,547,830 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X41,556,861 - 41,601,299 (+)NCBI
CeleraX21,378,634 - 21,423,365 (+)NCBICelera
Cytogenetic MapXq13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Smc1a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61991
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.