Gene: Ptpn1 (protein tyrosine phosphatase, non-receptor type 1) Rattus norvegicus
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Symbol: Ptpn1
Name: protein tyrosine phosphatase, non-receptor type 1
Description: ENCODES a protein that exhibits insulin receptor binding; protein phosphatase 2A binding; protein tyrosine phosphatase activity; INVOLVED IN protein dephosphorylation; regulation of insulin receptor signaling pathway; actin cytoskeleton reorganization (ortholog); PARTICIPATES IN insulin signaling pathway; epidermal growth factor/neuregulin signaling pathway; insulin-like growth factor signaling pathway; ASSOCIATED WITH B-cell lymphoma (ortholog); Diabetes Mellitus, Type 2 (ortholog); Hodgkin Disease (ortholog); FOUND IN cytoplasmic vesicle; cytosol; cytoplasm (ortholog); INTERACTS WITH 1,4-dithiothreitol; 17alpha-ethynylestradiol; 2,2',5,5'-tetrachlorobiphenyl
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC93562; protein-tyrosine phosphatase; protein-tyrosine phosphatase 1B; Ptp; PTP-1B; tyrosine-protein phosphatase non-receptor type 1
Orthologs:
Homo sapiens (human) : PTPN1 (protein tyrosine phosphatase, non-receptor type 1)  HGNC  AGR
Mus musculus (house mouse) : Ptpn1 (protein tyrosine phosphatase, non-receptor type 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Ptpn1 (protein tyrosine phosphatase, non-receptor type 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PTPN1 (protein tyrosine phosphatase, non-receptor type 1)
Canis lupus familiaris (dog) : PTPN1 (protein tyrosine phosphatase, non-receptor type 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptpn1 (protein tyrosine phosphatase, non-receptor type 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03164,665,462 - 164,711,936 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03170,816,897 - 170,866,071 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43159,070,473 - 159,116,792 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13158,976,466 - 159,025,198 (+)NCBI
Celera3155,215,176 - 155,261,496 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ptpn1
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61965
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE