Gene: Ptpn1 (protein tyrosine phosphatase, non-receptor type 1) Rattus norvegicus
Symbol: Ptpn1
Name: protein tyrosine phosphatase, non-receptor type 1
Description: ENCODES a protein that exhibits insulin receptor binding; protein phosphatase 2A binding; protein tyrosine phosphatase activity; INVOLVED IN protein dephosphorylation; regulation of insulin receptor signaling pathway; actin cytoskeleton reorganization (ortholog); PARTICIPATES IN insulin signaling pathway; epidermal growth factor/neuregulin signaling pathway; insulin-like growth factor signaling pathway; ASSOCIATED WITH Diabetes Mellitus, Type 2 (ortholog); Hodgkin Disease (ortholog); Insulin Resistance (ortholog); FOUND IN cytoplasmic vesicle; cytosol; cytoplasm (ortholog); INTERACTS WITH 1,4-dithiothreitol; 17alpha-ethynylestradiol; 2,2',5,5'-tetrachlorobiphenyl
Type: protein-coding
Also known as: MGC93562; protein-tyrosine phosphatase; protein-tyrosine phosphatase 1B; Ptp; PTP-1B; tyrosine-protein phosphatase non-receptor type 1
Homo sapiens (human) : PTPN1 (protein tyrosine phosphatase, non-receptor type 1)  HGNC  AGR
Mus musculus (house mouse) : Ptpn1 (protein tyrosine phosphatase, non-receptor type 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Ptpn1 (protein tyrosine phosphatase, non-receptor type 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PTPN1 (protein tyrosine phosphatase, non-receptor type 1)
Canis lupus familiaris (dog) : PTPN1 (protein tyrosine phosphatase, non-receptor type 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptpn1 (protein tyrosine phosphatase, non-receptor type 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03164,665,462 - 164,711,936 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03170,816,897 - 170,866,071 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43159,070,473 - 159,116,792 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13158,976,466 - 159,025,198 (+)NCBI
Celera3155,215,176 - 155,261,496 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ptpn1
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61965
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE