Gene: Map3k12 (mitogen activated protein kinase kinase kinase 12) Rattus norvegicus
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Symbol: Map3k12
Name: mitogen activated protein kinase kinase kinase 12
Description: ENCODES a protein that exhibits JUN kinase kinase kinase activity (ortholog); protein homodimerization activity (ortholog); protein kinase binding (ortholog); INVOLVED IN activation of JNKK activity (ortholog); activation of JUN kinase activity (ortholog); histone phosphorylation (ortholog); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; mitogen activated protein kinase signaling pathway; FOUND IN axon (ortholog); cytosol (ortholog); growth cone (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-ethoxyethanol; 2-methoxyethanol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DLK; dual leucine zipper bearing kinase; dual leucine zipper kinase; leucine-zipper protein kinase; MAPK-upstream kinase; Mitogen activated protein kinase 12 (Zipper (leucine) protein kinase); mitogen-activated protein kinase kinase kinase 12; mixed lineage kinase; MUK; PK; Zipper (leucine) protein kinase; Zpk
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07144,102,275 - 144,120,306 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07141,894,406 - 141,912,301 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47141,254,451 - 141,264,979 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17141,330,887 - 141,341,418 (-)NCBI
Celera7130,056,875 - 130,075,370 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Map3k12
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3988
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-11-20
Status: ACTIVE