Tnnt3 (troponin T3, fast skeletal type) - Rat Genome Database

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Gene: Tnnt3 (troponin T3, fast skeletal type) Rattus norvegicus
Analyze
Symbol: Tnnt3
Name: troponin T3, fast skeletal type
RGD ID: 3883
Description: Predicted to enable calcium-dependent protein binding activity and cytoskeletal protein binding activity. Predicted to contribute to actin binding activity. Involved in regulation of striated muscle contraction. Part of troponin complex. Human ortholog(s) of this gene implicated in distal arthrogryposis type 2B and distal arthrogryposis type 2B2. Orthologous to human TNNT3 (troponin T3, fast skeletal type); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: fast skeletal muscle troponin T; fast skeletal troponin T beta-1 isoform; fTnT; skeletal troponin T alpha-1 isoform; Tnt; tnTf; Troponin T fast skeletal; troponin T type 3 (skeletal, fast); troponin T, fast skeletal muscle; troponin T3; troponin T3, skeletal, fast
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81207,082,014 - 207,099,014 (+)NCBIGRCr8
mRatBN7.21197,652,535 - 197,669,736 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1197,652,431 - 197,669,535 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1206,025,246 - 206,042,256 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01213,111,112 - 213,128,127 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01205,785,265 - 205,802,280 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01215,666,628 - 215,683,628 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1215,666,628 - 215,683,628 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01222,561,418 - 222,578,418 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41202,748,063 - 202,761,965 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11202,908,518 - 202,917,537 (+)NCBI
Celera1195,269,899 - 195,286,899 (+)NCBICelera
Cytogenetic Map1q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
troponin complex  (IBA,IDA,IEA,ISO,TAS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway   (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bisoprolol pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway  (ISO)
carvedilol pharmacodynamics pathway  (ISO)
diltiazem pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
ibutilide pharmacodynamics pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway  (ISO)
nadolol pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
timolol pharmacodynamics pathway  (ISO)
verapamil pharmacodynamics pathway  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Origin of fetal troponin T: developmentally regulated splicing of a new exon in the fast troponin T gene. Briggs MM and Schachat F, Dev Biol 1993 Aug;158(2):503-9.
2. Coupled expression of troponin T and troponin I isoforms in single skeletal muscle fibers correlates with contractility. Brotto MA, etal., Am J Physiol Cell Physiol. 2006 Feb;290(2):C567-76. Epub 2005 Sep 28.
3. Differences in myofilament calcium sensitivity in rat psoas fibers reconstituted with troponin T isoforms containing the alpha- and beta-exons. Gallon CE, etal., Arch Biochem Biophys. 2006 Dec 15;456(2):127-34. Epub 2006 Jun 22.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Time-dependent changes in expression of troponin subunit isoforms in unloaded rat soleus muscle. Stevens L, etal., Am J Physiol Cell Physiol 2002 May;282(5):C1025-30.
12. Mutations in TNNT3 cause multiple congenital contractures: a second locus for distal arthrogryposis type 2B. Sung SS, etal., Am J Hum Genet. 2003 Jul;73(1):212-4.
Additional References at PubMed
PMID:1299083   PMID:2986851   PMID:3735424   PMID:6179945   PMID:6205765   PMID:8987992   PMID:9724539   PMID:15507453   PMID:17194691   PMID:19182904   PMID:21490260  


Genomics

Comparative Map Data
Tnnt3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81207,082,014 - 207,099,014 (+)NCBIGRCr8
mRatBN7.21197,652,535 - 197,669,736 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1197,652,431 - 197,669,535 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1206,025,246 - 206,042,256 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01213,111,112 - 213,128,127 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01205,785,265 - 205,802,280 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01215,666,628 - 215,683,628 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1215,666,628 - 215,683,628 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01222,561,418 - 222,578,418 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41202,748,063 - 202,761,965 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11202,908,518 - 202,917,537 (+)NCBI
Celera1195,269,899 - 195,286,899 (+)NCBICelera
Cytogenetic Map1q41NCBI
TNNT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38111,919,552 - 1,938,702 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl111,919,703 - 1,938,706 (+)EnsemblGRCh38hg38GRCh38
GRCh37111,940,933 - 1,959,932 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36111,897,445 - 1,916,514 (+)NCBINCBI36Build 36hg18NCBI36
Build 34111,900,668 - 1,916,510NCBI
Celera1111,177 - 30,313 (+)NCBICelera
Cytogenetic Map11p15.5NCBI
HuRef111,709,242 - 1,728,503 (+)NCBIHuRef
CHM1_1111,939,717 - 1,958,858 (+)NCBICHM1_1
T2T-CHM13v2.0111,983,592 - 2,002,746 (+)NCBIT2T-CHM13v2.0
Tnnt3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397142,052,530 - 142,069,746 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7142,052,573 - 142,069,746 (+)EnsemblGRCm39 Ensembl
GRCm387142,498,771 - 142,516,213 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7142,498,836 - 142,516,009 (+)EnsemblGRCm38mm10GRCm38
MGSCv377149,684,741 - 149,701,914 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367142,308,233 - 142,325,393 (+)NCBIMGSCv36mm8
Celera7142,254,685 - 142,271,858 (+)NCBICelera
Cytogenetic Map7F5NCBI
cM Map787.94NCBI
Tnnt3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542213,702,015 - 13,718,915 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542213,702,015 - 13,718,915 (+)NCBIChiLan1.0ChiLan1.0
TNNT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v294,328,279 - 4,340,866 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1113,539,861 - 3,552,260 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0111,936,614 - 1,955,784 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1111,968,184 - 1,987,846 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl111,968,184 - 1,987,849 (+)Ensemblpanpan1.1panPan2
TNNT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11846,131,925 - 46,148,577 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1846,074,700 - 46,149,131 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1844,741,795 - 44,758,468 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01846,812,971 - 46,829,661 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1846,756,047 - 46,829,658 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11846,260,272 - 46,276,949 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01845,840,558 - 45,857,236 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01846,586,814 - 46,603,499 (+)NCBIUU_Cfam_GSD_1.0
Tnnt3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049471,551,243 - 1,567,924 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936816805,317 - 822,043 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936816805,360 - 822,044 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNNT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl21,299,174 - 1,316,517 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.121,297,826 - 1,316,865 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TNNT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111,718,729 - 1,738,271 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11,718,523 - 1,738,477 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603898,918,119 - 98,934,360 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tnnt3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476714,787,248 - 14,802,098 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476714,784,267 - 14,801,477 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tnnt3
45 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:416
Count of miRNA genes:64
Interacting mature miRNAs:71
Transcripts:ENSRNOT00000027563, ENSRNOT00000040598, ENSRNOT00000051425, ENSRNOT00000063918, ENSRNOT00000066135, ENSRNOT00000066896
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1102813953201278233Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1102813953201278233Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118944897199050459Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350581201284552Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1143506580212458660Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144017057197814409Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1144267353222987745Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1149448574221264292Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1151162512201278233Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512201278233Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1151162512201278233Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1151162512201278233Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1151162766225824951Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1154561505199561505Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1155866514200866514Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1156677124201278233Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1156677124218753816Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1158633083203633083Rat
2292222Bp307Blood pressure QTL 3073.060.0014arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393213533942Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393243914901Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164747424209747424Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1164747424209747424Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1167909849212909849Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1169537671214537671Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1169537671214537671Rat
1358294Bw37Body weight QTL 3750.000011body mass (VT:0001259)body weight (CMO:0000012)1171310381216310381Rat
2293689Bss47Bone structure and strength QTL 477.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)1171629477216629477Rat
2293693Bss22Bone structure and strength QTL 2233.520.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1171629477216629477Rat
2300161Bmd43Bone mineral density QTL 438.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
2300174Bmd42Bone mineral density QTL 428.40.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)1171629477216629477Rat
2300187Bmd41Bone mineral density QTL 418.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
2293654Bss30Bone structure and strength QTL 3032.650.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1171629477216629477Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1171629477216629477Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1171629477216629477Rat
1549830Bss1Bone structure and strength QTL 14.8femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1172609619217609619Rat
631214Bw61Body weight QTL613.40.0001intramuscular adipose amount (VT:0010044)intramuscular fat area (CMO:0001162)1173108781218108781Rat
70163Bw20Body weight QTL 205.1body mass (VT:0001259)body weight (CMO:0000012)1174133260219133260Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1176426412257976495Rat
1600380Niddm70Non-insulin dependent diabetes mellitus QTL 703.10.0008blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1176550523221550523Rat
10059600Bp378Blood pressure QTL 3783.080.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1176869060221869060Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1177227632256448636Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
1558658Bw59Body weight QTL 593.50.0003body mass (VT:0001259)body weight (CMO:0000012)1178784622223784622Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1178810256240830002Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
1302787Stl25Serum triglyceride level QTL 252.70.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1180359209210702199Rat
6903303Scl34Serum cholesterol QTL 342.50.0033blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)1180359209218108781Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1181133855226133855Rat
724559Pancm1Pancreatic morphology QTL 17.1islet of Langerhans morphology trait (VT:0005215)pancreatic islet damage composite score (CMO:0001156)1181759564214537555Rat
2293083Iddm25Insulin dependent diabetes mellitus QTL 254.18blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1181829673224569684Rat
634312Bp143Blood pressure QTL 14330.0002arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1182623426219932796Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1183970203243914901Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1183970203243914901Rat
631838Niddm36Non-insulin dependent diabetes mellitus QTL 360.01insulin secretion trait (VT:0003564)calculated pancreatic islet insulin release measurement (CMO:0001217)1184550676229550676Rat
1300145Rf7Renal function QTL 72.96urine creatinine amount (VT:0010540)urine creatinine level (CMO:0000125)1185145134221264292Rat
1359018Hrtrt20Heart rate QTL 203.08heart pumping trait (VT:2000009)heart rate (CMO:0000002)1185356336202902618Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1185356336231689108Rat
1582206Kidm33Kidney mass QTL 336.9kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1188377360224054420Rat
6480780Insul18Insulin level QTL 184.11blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1189607473200611765Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1191019702246062233Rat
10059590Kidm44Kidney mass QTL 443.420.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1191033875236033875Rat
631260Tcas2Tongue tumor susceptibility QTL 24.93tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)1192485903199050587Rat
1358191Ept10Estrogen-induced pituitary tumorigenesis QTL 103.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)1192825253243914732Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1193113876238113876Rat
634338Hcar4Hepatocarcinoma resistance QTL 44.6liver integrity trait (VT:0010547)liver tumorous lesion number to liver area ratio (CMO:0001210)1193422268214537671Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1195804352257091168Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1196248093241248093Rat
1358292Cm37Cardiac mass QTL 376.20.00000081heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1196248093241248093Rat
6480777Insul17Insulin level QTL 173.86blood insulin amount (VT:0001560)blood insulin level area under curve (AUC) (CMO:0000351)1197260913198211706Rat
6480783Insul19Insulin level QTL 194.33blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1197489281200611765Rat

Markers in Region
D1Arb23  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21197,655,883 - 197,656,196 (+)MAPPERmRatBN7.2
Rnor_6.01215,669,977 - 215,670,289NCBIRnor6.0
Rnor_5.01222,564,767 - 222,565,079UniSTSRnor5.0
RGSC_v3.41202,748,498 - 202,748,810UniSTSRGSC3.4
Celera1195,273,248 - 195,273,560UniSTS
FHH x ACI Map195.53UniSTS
FHH x ACI Map195.53RGD
Cytogenetic Map1q41-q42UniSTS
D1Wox55  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21197,655,456 - 197,655,660 (+)MAPPERmRatBN7.2
Rnor_6.01215,669,550 - 215,669,753NCBIRnor6.0
Rnor_5.01222,564,340 - 222,564,543UniSTSRnor5.0
RGSC_v3.41202,748,071 - 202,748,274UniSTSRGSC3.4
Celera1195,272,821 - 195,273,024UniSTS
Cytogenetic Map1q41-q42UniSTS
RH139831  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21197,656,672 - 197,656,877 (+)MAPPERmRatBN7.2
Rnor_6.01215,670,766 - 215,670,970NCBIRnor6.0
Rnor_5.01222,565,556 - 222,565,760UniSTSRnor5.0
RGSC_v3.41202,749,287 - 202,749,491UniSTSRGSC3.4
Celera1195,274,037 - 195,274,241UniSTS
RH 3.4 Map11437.5UniSTS
Cytogenetic Map1q41-q42UniSTS
Tnnt3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21197,665,586 - 197,666,040 (+)MAPPERmRatBN7.2
Rnor_6.01215,679,680 - 215,680,133NCBIRnor6.0
Rnor_5.01222,574,470 - 222,574,923UniSTSRnor5.0
Celera1195,282,951 - 195,283,404UniSTS
Cytogenetic Map1q41-q42UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 8 11 8
Medium 2 4 17 8 19 8 10 20 10
Low 1 39 25 18 18 58 24 16 1
Below cutoff 15 15 15 16 1 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001270664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_031532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC098563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC132720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB612473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ062204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ273678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M15202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U04979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U04980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U04981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000040598   ⟹   ENSRNOP00000049386
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1197,652,431 - 197,669,535 (+)Ensembl
Rnor_6.0 Ensembl1215,666,628 - 215,683,622 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000051425   ⟹   ENSRNOP00000050785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1197,652,535 - 197,669,535 (+)Ensembl
Rnor_6.0 Ensembl1215,666,628 - 215,683,628 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000063918   ⟹   ENSRNOP00000062891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1197,652,535 - 197,669,535 (+)Ensembl
Rnor_6.0 Ensembl1215,666,628 - 215,683,628 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000066135   ⟹   ENSRNOP00000062653
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1197,652,535 - 197,669,535 (+)Ensembl
Rnor_6.0 Ensembl1215,666,628 - 215,683,628 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000066896   ⟹   ENSRNOP00000059829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1197,652,535 - 197,669,535 (+)Ensembl
Rnor_6.0 Ensembl1215,666,628 - 215,683,628 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000080339   ⟹   ENSRNOP00000075571
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1197,664,237 - 197,667,213 (+)Ensembl
Rnor_6.0 Ensembl1215,666,628 - 215,683,628 (+)Ensembl
RefSeq Acc Id: NM_001270664   ⟹   NP_001257593
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81207,082,014 - 207,099,014 (+)NCBI
mRatBN7.21197,652,535 - 197,669,535 (+)NCBI
Rnor_6.01215,666,628 - 215,683,628 (+)NCBI
Rnor_5.01222,561,418 - 222,578,418 (+)NCBI
Celera1195,269,899 - 195,286,899 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270665   ⟹   NP_001257594
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81207,082,014 - 207,099,014 (+)NCBI
mRatBN7.21197,652,535 - 197,669,535 (+)NCBI
Rnor_6.01215,666,628 - 215,683,628 (+)NCBI
Rnor_5.01222,561,418 - 222,578,418 (+)NCBI
Celera1195,269,899 - 195,286,899 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270666   ⟹   NP_001257595
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81207,082,014 - 207,099,014 (+)NCBI
mRatBN7.21197,652,535 - 197,669,535 (+)NCBI
Rnor_6.01215,666,628 - 215,683,628 (+)NCBI
Rnor_5.01222,561,418 - 222,578,418 (+)NCBI
Celera1195,269,899 - 195,286,899 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270668   ⟹   NP_001257597
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81207,082,014 - 207,099,014 (+)NCBI
mRatBN7.21197,652,535 - 197,669,535 (+)NCBI
Rnor_6.01215,666,628 - 215,683,628 (+)NCBI
Rnor_5.01222,561,418 - 222,578,418 (+)NCBI
Celera1195,269,899 - 195,286,899 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270670   ⟹   NP_001257599
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81207,082,014 - 207,099,014 (+)NCBI
mRatBN7.21197,652,535 - 197,669,535 (+)NCBI
Rnor_6.01215,666,628 - 215,683,628 (+)NCBI
Rnor_5.01222,561,418 - 222,578,418 (+)NCBI
Celera1195,269,899 - 195,286,899 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270671   ⟹   NP_001257600
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81207,082,014 - 207,099,014 (+)NCBI
mRatBN7.21197,652,535 - 197,669,535 (+)NCBI
Rnor_6.01215,666,628 - 215,683,628 (+)NCBI
Rnor_5.01222,561,418 - 222,578,418 (+)NCBI
Celera1195,269,899 - 195,286,899 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270672   ⟹   NP_001257601
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81207,082,014 - 207,099,014 (+)NCBI
mRatBN7.21197,652,535 - 197,669,535 (+)NCBI
Rnor_6.01215,666,628 - 215,683,628 (+)NCBI
Rnor_5.01222,561,418 - 222,578,418 (+)NCBI
Celera1195,269,899 - 195,286,899 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270673   ⟹   NP_001257602
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81207,082,014 - 207,099,014 (+)NCBI
mRatBN7.21197,652,535 - 197,669,535 (+)NCBI
Rnor_6.01215,666,628 - 215,683,628 (+)NCBI
Rnor_5.01222,561,418 - 222,578,418 (+)NCBI
Celera1195,269,899 - 195,286,899 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270675   ⟹   NP_001257604
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81207,082,014 - 207,099,014 (+)NCBI
mRatBN7.21197,652,535 - 197,669,535 (+)NCBI
Rnor_6.01215,666,628 - 215,683,628 (+)NCBI
Rnor_5.01222,561,418 - 222,578,418 (+)NCBI
Celera1195,269,899 - 195,286,899 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270676   ⟹   NP_001257605
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81207,082,014 - 207,099,014 (+)NCBI
mRatBN7.21197,652,535 - 197,669,535 (+)NCBI
Rnor_6.01215,666,628 - 215,683,628 (+)NCBI
Rnor_5.01222,561,418 - 222,578,418 (+)NCBI
Celera1195,269,899 - 195,286,899 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270677   ⟹   NP_001257606
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81207,082,014 - 207,099,014 (+)NCBI
mRatBN7.21197,652,535 - 197,669,535 (+)NCBI
Rnor_6.01215,666,628 - 215,683,628 (+)NCBI
Rnor_5.01222,561,418 - 222,578,418 (+)NCBI
Celera1195,269,899 - 195,286,899 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270678   ⟹   NP_001257607
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81207,082,014 - 207,099,014 (+)NCBI
mRatBN7.21197,652,535 - 197,669,535 (+)NCBI
Rnor_6.01215,666,628 - 215,683,628 (+)NCBI
Rnor_5.01222,561,418 - 222,578,418 (+)NCBI
Celera1195,269,899 - 195,286,899 (+)NCBI
Sequence:
RefSeq Acc Id: NM_031532   ⟹   NP_113720
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81207,082,014 - 207,099,014 (+)NCBI
mRatBN7.21197,652,535 - 197,669,535 (+)NCBI
Rnor_6.01215,666,628 - 215,683,628 (+)NCBI
Rnor_5.01222,561,418 - 222,578,418 (+)NCBI
RGSC_v3.41202,748,063 - 202,761,965 (+)RGD
Celera1195,269,899 - 195,286,899 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063281060   ⟹   XP_063137130
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81207,082,057 - 207,099,009 (+)NCBI
RefSeq Acc Id: XM_063281061   ⟹   XP_063137131
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81207,082,073 - 207,099,009 (+)NCBI
RefSeq Acc Id: XM_063281062   ⟹   XP_063137132
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81207,082,073 - 207,099,009 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001257593 (Get FASTA)   NCBI Sequence Viewer  
  NP_001257594 (Get FASTA)   NCBI Sequence Viewer  
  NP_001257595 (Get FASTA)   NCBI Sequence Viewer  
  NP_001257597 (Get FASTA)   NCBI Sequence Viewer  
  NP_001257599 (Get FASTA)   NCBI Sequence Viewer  
  NP_001257600 (Get FASTA)   NCBI Sequence Viewer  
  NP_001257601 (Get FASTA)   NCBI Sequence Viewer  
  NP_001257602 (Get FASTA)   NCBI Sequence Viewer  
  NP_001257604 (Get FASTA)   NCBI Sequence Viewer  
  NP_001257605 (Get FASTA)   NCBI Sequence Viewer  
  NP_001257606 (Get FASTA)   NCBI Sequence Viewer  
  NP_001257607 (Get FASTA)   NCBI Sequence Viewer  
  NP_113720 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137130 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137131 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137132 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA16032 (Get FASTA)   NCBI Sequence Viewer  
  AAA16033 (Get FASTA)   NCBI Sequence Viewer  
  AAA16034 (Get FASTA)   NCBI Sequence Viewer  
  AAA96440 (Get FASTA)   NCBI Sequence Viewer  
  AAA96441 (Get FASTA)   NCBI Sequence Viewer  
  AAA96442 (Get FASTA)   NCBI Sequence Viewer  
  AAA96443 (Get FASTA)   NCBI Sequence Viewer  
  AAA96444 (Get FASTA)   NCBI Sequence Viewer  
  AAA96446 (Get FASTA)   NCBI Sequence Viewer  
  AAA96447 (Get FASTA)   NCBI Sequence Viewer  
  AAA96448 (Get FASTA)   NCBI Sequence Viewer  
  AAA96449 (Get FASTA)   NCBI Sequence Viewer  
  AAA96450 (Get FASTA)   NCBI Sequence Viewer  
  AAA96451 (Get FASTA)   NCBI Sequence Viewer  
  AAA96452 (Get FASTA)   NCBI Sequence Viewer  
  AAA96453 (Get FASTA)   NCBI Sequence Viewer  
  AAA96456 (Get FASTA)   NCBI Sequence Viewer  
  AAA96457 (Get FASTA)   NCBI Sequence Viewer  
  AAA96458 (Get FASTA)   NCBI Sequence Viewer  
  AAA96459 (Get FASTA)   NCBI Sequence Viewer  
  AAA96460 (Get FASTA)   NCBI Sequence Viewer  
  AAA96461 (Get FASTA)   NCBI Sequence Viewer  
  AAA96462 (Get FASTA)   NCBI Sequence Viewer  
  AAA96463 (Get FASTA)   NCBI Sequence Viewer  
  AAA96464 (Get FASTA)   NCBI Sequence Viewer  
  AAA96465 (Get FASTA)   NCBI Sequence Viewer  
  AAA96468 (Get FASTA)   NCBI Sequence Viewer  
  AAA96469 (Get FASTA)   NCBI Sequence Viewer  
  AAA96472 (Get FASTA)   NCBI Sequence Viewer  
  AAA96473 (Get FASTA)   NCBI Sequence Viewer  
  AAA96474 (Get FASTA)   NCBI Sequence Viewer  
  AAA96475 (Get FASTA)   NCBI Sequence Viewer  
  AAA96476 (Get FASTA)   NCBI Sequence Viewer  
  AAA96477 (Get FASTA)   NCBI Sequence Viewer  
  AAA96478 (Get FASTA)   NCBI Sequence Viewer  
  AAA96479 (Get FASTA)   NCBI Sequence Viewer  
  AAA96480 (Get FASTA)   NCBI Sequence Viewer  
  AAA96481 (Get FASTA)   NCBI Sequence Viewer  
  AAA96483 (Get FASTA)   NCBI Sequence Viewer  
  AAY59901 (Get FASTA)   NCBI Sequence Viewer  
  ABB51539 (Get FASTA)   NCBI Sequence Viewer  
  EDM12137 (Get FASTA)   NCBI Sequence Viewer  
  EDM12138 (Get FASTA)   NCBI Sequence Viewer  
  EDM12139 (Get FASTA)   NCBI Sequence Viewer  
  EDM12140 (Get FASTA)   NCBI Sequence Viewer  
  EDM12141 (Get FASTA)   NCBI Sequence Viewer  
  EDM12142 (Get FASTA)   NCBI Sequence Viewer  
  EDM12143 (Get FASTA)   NCBI Sequence Viewer  
  EDM12144 (Get FASTA)   NCBI Sequence Viewer  
  EDM12145 (Get FASTA)   NCBI Sequence Viewer  
  EDM12146 (Get FASTA)   NCBI Sequence Viewer  
  EDM12147 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000049386.3
  ENSRNOP00000050785.4
  ENSRNOP00000059829
  ENSRNOP00000059829.2
  ENSRNOP00000062653.3
  ENSRNOP00000062891.4
  ENSRNOP00000075571.2
GenBank Protein P09739 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_113720   ⟸   NM_031532
- Peptide Label: isoform 8
- UniProtKB: A6HY60 (UniProtKB/TrEMBL),   A6HY62 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257595   ⟸   NM_001270666
- Peptide Label: isoform 2
- UniProtKB: A6HY61 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257594   ⟸   NM_001270665
- Peptide Label: isoform 1
- UniProtKB: Q304F4 (UniProtKB/Swiss-Prot),   P09740 (UniProtKB/Swiss-Prot),   Q4PPA0 (UniProtKB/Swiss-Prot),   P09739 (UniProtKB/Swiss-Prot),   A6HY59 (UniProtKB/TrEMBL),   A6HY62 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257605   ⟸   NM_001270676
- Peptide Label: isoform 10
- UniProtKB: A6HY61 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257602   ⟸   NM_001270673
- Peptide Label: isoform 7
- UniProtKB: A6HY62 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257607   ⟸   NM_001270678
- Peptide Label: isoform 13
- UniProtKB: A6HY61 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257604   ⟸   NM_001270675
- Peptide Label: isoform 9
- UniProtKB: A6HY61 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257601   ⟸   NM_001270672
- Peptide Label: isoform 6
- UniProtKB: A6HY62 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257599   ⟸   NM_001270670
- Peptide Label: isoform 4
- UniProtKB: A6HY61 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257600   ⟸   NM_001270671
- Peptide Label: isoform 5
- UniProtKB: A6HY62 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257597   ⟸   NM_001270668
- Peptide Label: isoform 3
- UniProtKB: A6HY61 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257593   ⟸   NM_001270664
- Peptide Label: isoform 11
- UniProtKB: A6HY62 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257606   ⟸   NM_001270677
- Peptide Label: isoform 12
- UniProtKB: A6HY62 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000075571   ⟸   ENSRNOT00000080339
RefSeq Acc Id: ENSRNOP00000062891   ⟸   ENSRNOT00000063918
RefSeq Acc Id: ENSRNOP00000050785   ⟸   ENSRNOT00000051425
RefSeq Acc Id: ENSRNOP00000062653   ⟸   ENSRNOT00000066135
RefSeq Acc Id: ENSRNOP00000059829   ⟸   ENSRNOT00000066896
RefSeq Acc Id: ENSRNOP00000049386   ⟸   ENSRNOT00000040598
RefSeq Acc Id: XP_063137130   ⟸   XM_063281060
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063137132   ⟸   XM_063281062
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063137131   ⟸   XM_063281061
- Peptide Label: isoform X2
- UniProtKB: A0A0H2UHY9 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P09739-F1-model_v2 AlphaFold P09739 1-259 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690563
Promoter ID:EPDNEW_R1088
Type:multiple initiation site
Name:Tnnt3_1
Description:troponin T3, fast skeletal type
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01215,666,666 - 215,666,726EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3883 AgrOrtholog
BioCyc Gene G2FUF-56910 BioCyc
Ensembl Genes ENSRNOG00000020332 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000040598.6 UniProtKB/TrEMBL
  ENSRNOT00000051425.6 UniProtKB/TrEMBL
  ENSRNOT00000063918.5 UniProtKB/TrEMBL
  ENSRNOT00000066135.4 UniProtKB/TrEMBL
  ENSRNOT00000066896 ENTREZGENE
  ENSRNOT00000066896.5 UniProtKB/TrEMBL
  ENSRNOT00000080339.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro TNNT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Troponin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Troponin_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24838 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 24838 ENTREZGENE
PANTHER PTHR11521 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11521:SF4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Troponin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tnnt3 PhenoGen
RatGTEx ENSRNOG00000020332 RatGTEx
Superfamily-SCOP SSF90250 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JSW6_RAT UniProtKB/TrEMBL
  A0A0G2KAY2_RAT UniProtKB/TrEMBL
  A0A0H2UHY9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QT13_RAT UniProtKB/TrEMBL
  A0A8L2QUB8_RAT UniProtKB/TrEMBL
  A0A8L2QUG8_RAT UniProtKB/TrEMBL
  A6HY56_RAT UniProtKB/TrEMBL
  A6HY57_RAT UniProtKB/TrEMBL
  A6HY58_RAT UniProtKB/TrEMBL
  A6HY59 ENTREZGENE, UniProtKB/TrEMBL
  A6HY60 ENTREZGENE, UniProtKB/TrEMBL
  A6HY61 ENTREZGENE, UniProtKB/TrEMBL
  A6HY62 ENTREZGENE, UniProtKB/TrEMBL
  A6HY63_RAT UniProtKB/TrEMBL
  A6HY64_RAT UniProtKB/TrEMBL
  P09739 ENTREZGENE
  P09740 ENTREZGENE
  Q304F4 ENTREZGENE
  Q4PPA0 ENTREZGENE
  TNNT3_RAT UniProtKB/Swiss-Prot
UniProt Secondary P09740 UniProtKB/Swiss-Prot
  Q304F4 UniProtKB/Swiss-Prot
  Q4PPA0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-24 Tnnt3  troponin T3, fast skeletal type  Tnnt3  troponin T type 3 (skeletal, fast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-23 Tnnt3  troponin T type 3 (skeletal, fast)  Tnnt3  troponin T3, skeletal, fast  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Tnnt3  troponin T3, skeletal, fast    troponin T3  Name updated 1299863 APPROVED
2002-06-10 Tnnt3  Troponin T, fast skeletal      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference