Neu2 (neuraminidase 2) - Rat Genome Database

Name: Neu2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Neu2 (neuraminidase 2) Rattus norvegicus

Analyze

Symbol:

Neu2

Name:

neuraminidase 2

RGD ID:

3164

Description:

Enables exo-alpha-sialidase activity. Involved in positive regulation of myoblast differentiation; positive regulation of myotube differentiation; and response to ethanol. Predicted to be located in cytosol. Predicted to be part of catalytic complex. Predicted to be active in lysosome and membrane. Orthologous to human NEU2 (neuraminidase 2); PARTICIPATES IN sphingolipid metabolic pathway; INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

cytosolic sialidase; MGC108717; N-acetyl-alpha-neuraminidase 2; sialidase 2; sialidase 2 (cytosolic sialidase); sialidase-2

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NEU2 (neuraminidase 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Neu2 (neuraminidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Neu2 (neuraminidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NEU2 (neuraminidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NEU2 (neuraminidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Neu2 (neuraminidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NEU2 (neuraminidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NEU2 (neuraminidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Neu2 (neuraminidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	DLG2 (discs large MAGUK scaffold protein 2)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	NEU2 (neuraminidase 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Neu2 (neuraminidase 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	95,666,338 - 95,715,209 (+)	NCBI		GRCr8
mRatBN7.2	9	88,218,494 - 88,267,356 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	88,249,135 - 88,267,355 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	96,688,673 - 96,691,886 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	101,824,744 - 101,827,957 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	100,192,362 - 100,195,578 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	94,702,095 - 94,724,903 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	94,702,129 - 94,724,902 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	94,396,233 - 94,444,063 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	86,553,196 - 86,556,412 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	86,736,614 - 86,739,826 (+)	NCBI
Celera	9	85,673,821 - 85,677,037 (+)	NCBI		Celera
Cytogenetic Map	9	q35	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Joubert syndrome 22 (ISO)

Perlman syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,1-dichloroethene (ISO)

1,2,4-trimethylbenzene (EXP)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-trinitrotoluene (EXP)

2,4-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

3H-1,2-dithiole-3-thione (EXP)

4,4'-diaminodiphenylmethane (ISO)

4-hydroxyphenyl retinamide (ISO)

5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (EXP)

6-propyl-2-thiouracil (EXP)

amiodarone (EXP)

ammonium chloride (EXP)

arsenous acid (ISO)

benzbromarone (EXP)

benzo[a]pyrene (EXP,ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP)

carbon nanotube (ISO)

CGP 52608 (ISO)

chrysene (ISO)

clofibrate (EXP)

cobalt dichloride (EXP)

dexamethasone (EXP)

diarsenic trioxide (ISO)

ethanol (ISO)

furan (EXP)

graphite (EXP)

L-ethionine (EXP)

omeprazole (EXP)

ozone (ISO)

p-toluidine (EXP)

paracetamol (ISO)

pirinixic acid (EXP)

pregnenolone 16alpha-carbonitrile (EXP)

rac-lactic acid (ISO)

silver atom (ISO)

silver(0) (ISO)

streptozocin (EXP)

tamoxifen (ISO)

testosterone (EXP)

tetrachloromethane (EXP)

tetraphene (ISO)

thioacetamide (EXP)

trichloroethene (EXP)

triphenyl phosphate (EXP)

triptonide (ISO)

valproic acid (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

ganglioside catabolic process (IBA,IEA,ISO,ISS)

glycoprotein catabolic process (IEA,ISO)

lipid catabolic process (IEA)

oligosaccharide catabolic process (IBA,IEA,ISO,ISS)

positive regulation of myoblast differentiation (IDA)

positive regulation of myotube differentiation (IMP)

response to ethanol (IEP)

Cellular Component

catalytic complex (IEA,ISO)

cytoplasm (IBA,IEA)

cytosol (IEA,ISO)

intracellular membrane-bounded organelle (IEA)

lysosome (IBA)

membrane (IBA,IEA)

Molecular Function

exo-alpha-(2->3)-sialidase activity (IEA,ISO,ISS)

exo-alpha-(2->6)-sialidase activity (IEA)

exo-alpha-(2->8)-sialidase activity (IEA,ISO)

exo-alpha-sialidase activity (IBA,IDA,IEA,ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

sphingolipid metabolic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	An investigation of the activity of recombinant rat skeletal muscle cytosolic sialidase.	Albouz-Abo S, etal., FEBS Lett. 2005 Feb 14;579(5):1034-8. Epub 2005 Jan 13.
2.	Overexpression of cytosolic sialidase Neu2 induces myoblast differentiation in C2C12 cells.	Fanzani A, etal., FEBS Lett. 2003 Jul 17;547(1-3):183-8.
3.	Chronic ethanol consumption upregulates the cytosolic and plasma membrane sialidase genes, but down regulates lysosomal membrane sialidase gene in rat liver.	Garige M, etal., Metabolism. 2006 Jun;55(6):803-10.
4.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
6.	Molecular cloning and expression of cDNA encoding rat skeletal muscle cytosolic sialidase.	Miyagi T, etal., J Biol Chem 1993 Dec 15;268(35):26435-40.
7.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
9.	GOA pipeline	RGD automated data pipeline
10.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
11.	Involvement of an endogenous sialidase in skeletal muscle cell differentiation.	Sato K and Miyagi T, Biochem Biophys Res Commun. 1996 Apr 25;221(3):826-30.
12.	[Immunohistochemical localization of cytosolic sialidase in the epithelium of rat cornea and conjunctiva].	Uehara F, etal., Nippon Ganka Gakkai Zasshi. 1997 Sep;101(9):707-10.

Additional References at PubMed

PMID:8563137	PMID:12477932	PMID:18384747	PMID:19371771	PMID:22228546	PMID:26193330

Genomics

Comparative Map Data

Neu2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	95,666,338 - 95,715,209 (+)	NCBI		GRCr8
mRatBN7.2	9	88,218,494 - 88,267,356 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	88,249,135 - 88,267,355 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	96,688,673 - 96,691,886 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	101,824,744 - 101,827,957 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	100,192,362 - 100,195,578 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	94,702,095 - 94,724,903 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	94,702,129 - 94,724,902 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	94,396,233 - 94,444,063 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	86,553,196 - 86,556,412 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	86,736,614 - 86,739,826 (+)	NCBI
Celera	9	85,673,821 - 85,677,037 (+)	NCBI		Celera
Cytogenetic Map	9	q35	NCBI

NEU2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	233,032,672 - 233,035,057 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	233,032,672 - 233,035,057 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	233,897,382 - 233,899,767 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	233,605,626 - 233,608,011 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	233,722,886 - 233,725,272	NCBI
Celera	2	227,661,195 - 227,663,580 (+)	NCBI		Celera
Cytogenetic Map	2	q37.1	NCBI
HuRef	2	225,744,667 - 225,747,052 (+)	NCBI		HuRef
CHM1_1	2	233,903,172 - 233,905,557 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	233,520,063 - 233,522,448 (+)	NCBI		T2T-CHM13v2.0

Neu2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	87,501,749 - 87,525,567 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	87,437,611 - 87,525,567 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	87,574,027 - 87,597,845 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	87,509,889 - 87,597,845 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	89,470,602 - 89,494,420 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	89,425,721 - 89,428,998 (+)	NCBI		MGSCv36	mm8
Celera	1	90,540,068 - 90,564,044 (+)	NCBI		Celera
Cytogenetic Map	1	D	NCBI
cM Map	1	44.44	NCBI

Neu2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955453	3,052,297 - 3,061,791 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955453	3,054,626 - 3,063,070 (-)	NCBI	ChiLan1.0	ChiLan1.0

NEU2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	135,634,219 - 135,636,729 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	135,649,184 - 135,651,694 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	120,260,420 - 120,262,930 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	239,174,532 - 239,176,917 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	239,174,532 - 239,176,917 (+)	Ensembl	panpan1.1		panPan2

NEU2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	44,563,664 - 44,596,837 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	44,563,411 - 44,595,653 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	45,058,963 - 45,092,889 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	44,823,144 - 44,857,117 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	44,847,543 - 44,855,198 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	44,747,576 - 44,780,743 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	44,623,544 - 44,627,737 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	44,748,930 - 44,782,126 (+)	NCBI		UU_Cfam_GSD_1.0

Neu2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	186,759,883 - 186,764,743 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936525	4,177,085 - 4,179,692 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936525	4,177,085 - 4,179,692 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NEU2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	133,468,293 - 133,477,110 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	133,392,559 - 133,479,406 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	147,509,793 - 147,545,593 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NEU2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	119,064,910 - 119,069,595 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	119,066,733 - 119,069,118 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	80,438,488 - 80,441,155 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Neu2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624843	5,665,448 - 5,670,832 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624843	5,666,959 - 5,671,833 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Neu2
403 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	234
Count of miRNA genes:	152
Interacting mature miRNAs:	165
Transcripts:	ENSRNOT00000022818
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	25268044	114175309	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	25661188	100929786	Rat
8662828	Vetf6	Vascular elastic tissue fragility QTL 6	3.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	9	36962359	92058970	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	36962359	95410867	Rat
11353951	Bp394	Blood pressure QTL 394			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	44649921	89649921	Rat
12879506	Pur33	Proteinuria QTL 33			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	44649921	89649921	Rat
11353957	Bmd92	Bone mineral density QTL 92		0.01	tibia mineral mass (VT:1000283)	volumetric bone mineral density (CMO:0001553)	9	46114199	91114199	Rat
631656	Bp108	Blood pressure QTL 108	5.97	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	48598251	93598251	Rat
1578760	Cm53	Cardiac mass QTL 53	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	56771635	101771635	Rat
724515	Uae16	Urinary albumin excretion QTL 16	8		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	58163035	100929646	Rat
1300134	Bp185	Blood pressure QTL 185	3.73		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	61381434	104821652	Rat
1581580	Uae34	Urinary albumin excretion QTL 34			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	62072275	96470995	Rat
1578757	Pur6	Proteinuria QTL 6	3.3	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	62072275	96470995	Rat
61385	Edpm9	Estrogen-dependent pituitary mass QTL 9	3.43	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	63869687	108869687	Rat
731171	Glom6	Glomerulus QTL 6	2.8	0.0003	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	9	64573531	109573531	Rat
1354626	Bvd1	Brain ventricular dilatation QTL 1	3.73	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	9	75712843	111552878	Rat
4889852	Pur26	Proteinuria QTL 26	15	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	77813894	101597663	Rat
7794784	Mcs31	Mammary carcinoma susceptibility QTL 31	2.98		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	9	77813894	111552878	Rat
2303178	Bp334	Blood pressure QTL 334	3.7	0.01	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	79271511	91616855	Rat
2303178	Bp334	Blood pressure QTL 334	3.7	0.01	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	9	79271511	91616855	Rat
2303178	Bp334	Blood pressure QTL 334	3.7	0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	79271511	91616855	Rat
724547	Cm21	Cardiac mass QTL 21	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	9	79271511	102910209	Rat
4889943	Bss90	Bone structure and strength QTL 90	4.1		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	9	86369631	92058970	Rat

Markers in Region

RH131410

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	88,267,091 - 88,267,278 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	94,724,639 - 94,724,825	NCBI	Rnor6.0
Rnor_5.0	9	94,443,799 - 94,443,985	UniSTS	Rnor5.0
RGSC_v3.4	9	86,556,153 - 86,556,339	UniSTS	RGSC3.4
Celera	9	85,676,778 - 85,676,964	UniSTS
Cytogenetic Map	9	q36	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium							4	7	2				4
Low	3	21	34	25	5	25	4	4	48	17	25	9	4
Below cutoff		8	21	16	11	16			14	10	13	2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_017130	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006245361	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006245362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006245363	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006245364	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006245365	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008767209	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008767210	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008767211	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596302	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596303	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039083108	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039083109	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039083110	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC091154	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D16300	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D50606	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213221	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ216178	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000022818 ⟹ ENSRNOP00000022818

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	88,264,135 - 88,267,350 (+)	Ensembl
Rnor_6.0 Ensembl	9	94,721,681 - 94,724,902 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000080930 ⟹ ENSRNOP00000071166

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	88,254,009 - 88,267,355 (+)	Ensembl
Rnor_6.0 Ensembl	9	94,702,129 - 94,724,897 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000096067 ⟹ ENSRNOP00000087714

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	88,249,135 - 88,267,355 (+)	Ensembl

RefSeq Acc Id:

NM_017130 ⟹ NP_058826

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	95,711,988 - 95,715,204 (+)	NCBI
mRatBN7.2	9	88,264,135 - 88,267,351 (+)	NCBI
Rnor_6.0	9	94,721,682 - 94,724,898 (+)	NCBI
Rnor_5.0	9	94,396,233 - 94,444,063 (+)	NCBI
RGSC_v3.4	9	86,553,196 - 86,556,412 (+)	RGD
Celera	9	85,673,821 - 85,677,037 (+)	RGD

Sequence:

show sequence

GTCGGACAGCTGCAGAGAGCCACTTAGCAAGCTCCTCTACTCTCCTCAGGGTTAGCAGCTGAAG
GTTGTCACACATCTGTTGTGAGGGGAACTGGTTATGGCAGGAATCTATACAAAACCCACTTTTT
CGATTCTTGGGTAGAAGACTGCCAGGACGCTACAGCCGCACTGGCGAACGATCTCAGGCCCATG
GAGACCTGCCCCGTCCTCCAGAAAGAGACGCTGTTCCACACAGAAGTCTATGCTTACAGAATCC
CTGCTCTGCTCTACCTGAAGAAGCAGAAGACCCTGCTGGCCTTTGCAGAAAAGCGAGCCAGCAG
GACGGATGAGCATGCTGAGTTGATTGTCCTGCGAAGAGGGAGCTACAATGGAGCCACCAACCAT
GTCAAGTGGCAACCTGAGGAAGTGGTGACCCAAGCCCAGCTGGAGGGCCACCGCTCCATGAATC
CATGTCCCTTGTATGACAAGCAAACAAAGACCCTCTTCCTTTTCTTCATTGCTGTCCCTGGGCG
TGTATCAGAACAGCATCAGCTCCAAACTAGGGTTAATGTCACACGGCTATGCCGTGTCACCAGC
ACCGATTATGGGATGAACTGGAGCCCCGTCCAGGACCTCACAGAGACCACCATTGGCAGCACCC
ACCAGGACTGGGCCACATTTGCTGTGGGTCCAGGGCACTGTCTGCAGCTGCGGAACAGAGCTGG
GAGCCTGCTGGTACCTGCTTATGCCTACCAGAAGCTGCACCCTGTCCATAAACCTACCCCCTTT
GCCTTCTGCTTCATCAGCCTTGACCACGGGCACACGTGGGAACTAGGGAACTTTGTGTCTGAGA
ACTCACTGGAGTGTCAGGTGGCTGAGGTTGGCACTGGTGCTCATAGGGTGGTATATCTCAATGC
TAGGAGCTTCATAGGAGCTAGAGTCCAGGCACAAAGTCCTAACGATGGCCTGGATTTCCAGGAC
AACCAGGTAGTAAGTAAGCTTGTAGAGCCCCCCCACGGGTGTCATGGAAGTGTGGTCGCCTTCC
ACAGCCCCACCTCTAAGCCAGATGCCTTAGACATGTGGCTGCTTTATACCCACCCTACGGACTC
CAGGAATAGAACCAACCTGGGCGTGTACCTCAACCAGACGCCACTAGATCCCACAGCCTGGTCA
GAGCCCACCCTGCTAGCCACGGGCACCTGTGCCTACTCAGACTTGCAGAATATGGGGCGTGGCC
CTGATGGGTCCCCACAGTTTGGGTGCCTGTATGAATCAGGTAACTATGACGAGATCATTTTCCT
CATGTTCACCCTGAAGCAAGCTTTTCCCACAGTACATGGTGCTCAGTGACCTCATTGCATGTGG
CTTCCAAAGGGCTTCCTGTGCTTCAGAACACCCGTCTCTCTTTCCTTCCAGCATCCTCTGGACT
CTTGAATCCAGCTCTTGGGTCTGTTCCTTGGGAGTATACAGAGAGTTTGGTCTCTTGACTCTTA
GCAAGTTTTGTTCTTTCAGCCTCCGAAAGTGGGTTCTATTTTCAGCCCAGAAATCAAAGGAGCC
TGACTTTCCTCAGCCTGTATGTATAAAGGCTGCCACTCTGCATGTTGGCTGTCACTATGTTAGC
TTAACCTGCCTGTTTCCCCATGCCTAGTTTTTGGATGAATATTAATAAATTAATTATCCTACTC
AAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006245361 ⟹ XP_006245423

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	95,711,990 - 95,715,209 (+)	NCBI
mRatBN7.2	9	88,264,137 - 88,267,356 (+)	NCBI
Rnor_6.0	9	94,721,619 - 94,724,903 (+)	NCBI
Rnor_5.0	9	94,396,233 - 94,444,063 (+)	NCBI

Sequence:

show sequence

CTTTGGAACAGCTTTCTAGGGCTCTGGAGTTATAAAAAGGCTCCCACGTGTCATTCCCTGACAG
TCGGACAGCTGCAGAGAGCCACTTAGCAAGCTCCTCTACTCTCCTCAGGATCTCAGGCCCATGG
AGACCTGCCCCGTCCTCCAGAAAGAGACGCTGTTCCACACAGAAGTCTATGCTTACAGAATCCC
TGCTCTGCTCTACCTGAAGAAGCAGAAGACCCTGCTGGCCTTTGCAGAAAAGCGAGCCAGCAGG
ACGGATGAGCATGCTGAGTTGATTGTCCTGCGAAGAGGGAGCTACAATGGAGCCACCAACCATG
TCAAGTGGCAACCTGAGGAAGTGGTGACCCAAGCCCAGCTGGAGGGCCACCGCTCCATGAATCC
ATGTCCCTTGTATGACAAGCAAACAAAGACCCTCTTCCTTTTCTTCATTGCTGTCCCTGGGCGT
GTATCAGAACAGCATCAGCTCCAAACTAGGGTTAATGTCACACGGCTATGCCGTGTCACCAGCA
CCGATTATGGGATGAACTGGAGCCCCGTCCAGGACCTCACAGAGACCACCATTGGCAGCACCCA
CCAGGACTGGGCCACATTTGCTGTGGGTCCAGGGCACTGTCTGCAGCTGCGGAACAGAGCTGGG
AGCCTGCTGGTACCTGCTTATGCCTACCAGAAGCTGCACCCTGTCCATAAACCTACCCCCTTTG
CCTTCTGCTTCATCAGCCTTGACCACGGGCACACGTGGGAACTAGGGAACTTTGTGTCTGAGAA
CTCACTGGAGTGTCAGGTGGCTGAGGTTGGCACTGGTGCTCATAGGGTGGTATATCTCAATGCT
AGGAGCTTCATAGGAGCTAGAGTCCAGGCACAAAGTCCTAACGATGGCCTGGATTTCCAGGACA
ACCAGGTAGTAAGTAAGCTTGTAGAGCCCCCCCACGGGTGTCATGGAAGTGTGGTCGCCTTCCA
CAGCCCCACCTCTAAGCCAGATGCCTTAGACATGTGGCTGCTTTATACCCACCCTACGGACTCC
AGGAATAGAACCAACCTGGGCGTGTACCTCAACCAGACGCCACTAGATCCCACAGCCTGGTCAG
AGCCCACCCTGCTAGCCACGGGCACCTGTGCCTACTCAGACTTGCAGAATATGGGGCGTGGCCC
TGATGGGTCCCCACAGTTTGGGTGCCTGTATGAATCAGGTAACTATGACGAGATCATTTTCCTC
ATGTTCACCCTGAAGCAAGCTTTTCCCACAGTACATGGTGCTCAGTGACCTCATTGCATGTGGC
TTCCAAAGGGCTTCCTGTGCTTCAGAACACCCGTCTCTCTTTCCTTCCAGCATCCTCTGGACTC
TTGAATCCAGCTCTTGGGTCTGTTCCTTGGGAGTATACAGAGAGTTTGGTCTCTTGACTCTTAG
CAAGTTTTGTTCTTTCAGCCTCCGAAAGTGGGTTCTATTTTCAGCCCAGAAATCAAAGGAGCCT
GACTTTCCTCAGCCTGTATGTATAAAGGCTGCCACTCTGCATGTTGGCTGTCACTATGTTAGCT
TAACCTGCCTGTTTCCCCATGCCTAGTTTTTGGATGAATATTAATAAATTAATTATCCTACTCA
GCCTA

hide sequence

RefSeq Acc Id:

XM_006245362 ⟹ XP_006245424

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	95,706,439 - 95,715,209 (+)	NCBI
mRatBN7.2	9	88,258,623 - 88,267,356 (+)	NCBI
Rnor_6.0	9	94,715,590 - 94,724,903 (+)	NCBI
Rnor_5.0	9	94,396,233 - 94,444,063 (+)	NCBI

Sequence:

show sequence

CTTCAGTTCCTGCCTCCAGGAACTGGAGGTTCCTGCCTTGAGCTTCTGTTCCTGACTTCTTTTA
GAGATGGAGTGTGGCCTGAGAGTTGTAAGATGAAATAAACCCCTTCCTCTCCAAGCTGCTTTTG
GTCATGGTGTTTATTATCACAGCAATGAAGAAGCACATTGAGAAGATGCACAGGAGTCTGCTGT
GCCTTCAGGCTGATGCCCTGTTATTGTCAGGGTTTCACAAAGGGAACTCCGTTCTGATTCTGAG
CCCCTCCATGCAGCTTAGGATCTACGTGAGGTTTTCTGTCATCATTTTCAGAGAGCCTGAGGGT
CTAAGGCATCATTTGGCCATCAACAGCTGAGCCAGAATGACAACTGGGCTCTACATGACTCTGA
CCTGCTCCTCCCATGAAAATTACAATTTTCCAAAGCCCAGGAAGTCTATTCCCACTGAGCACAT
ATTGCTCAATGCTTCCACTTATAAGAGACAACTTGACTCACGCTGCCCGAGGTCATCACTGATT
CAGGAGTTCTTCCAGACTAATGAGAGGTGGTATCCTAATTAGGCCAGGGCTGGGCCCACACTGT
GACATGATCCTGAGGGGTGCCTTGTCAGATGAGTGGACAGCAAATAGGAGGACTCCTTTTAGTT
TATATAGGCGTGAACTTACTGGGAAGCTGAGATTGGAGTCAAGACCTGGGGACTACAGTAGCCA
CAGAGACCTTCTAGAAACCAGATTCCCACTGACTCTGTCCTTCCATGACCAGAGCTCTCTGGAT
CCTGCTTGGCACATACTCCTGAAGATCTCAGGCCCATGGAGACCTGCCCCGTCCTCCAGAAAGA
GACGCTGTTCCACACAGAAGTCTATGCTTACAGAATCCCTGCTCTGCTCTACCTGAAGAAGCAG
AAGACCCTGCTGGCCTTTGCAGAAAAGCGAGCCAGCAGGACGGATGAGCATGCTGAGTTGATTG
TCCTGCGAAGAGGGAGCTACAATGGAGCCACCAACCATGTCAAGTGGCAACCTGAGGAAGTGGT
GACCCAAGCCCAGCTGGAGGGCCACCGCTCCATGAATCCATGTCCCTTGTATGACAAGCAAACA
AAGACCCTCTTCCTTTTCTTCATTGCTGTCCCTGGGCGTGTATCAGAACAGCATCAGCTCCAAA
CTAGGGTTAATGTCACACGGCTATGCCGTGTCACCAGCACCGATTATGGGATGAACTGGAGCCC
CGTCCAGGACCTCACAGAGACCACCATTGGCAGCACCCACCAGGACTGGGCCACATTTGCTGTG
GGTCCAGGGCACTGTCTGCAGCTGCGGAACAGAGCTGGGAGCCTGCTGGTACCTGCTTATGCCT
ACCAGAAGCTGCACCCTGTCCATAAACCTACCCCCTTTGCCTTCTGCTTCATCAGCCTTGACCA
CGGGCACACGTGGGAACTAGGGAACTTTGTGTCTGAGAACTCACTGGAGTGTCAGGTGGCTGAG
GTTGGCACTGGTGCTCATAGGGTGGTATATCTCAATGCTAGGAGCTTCATAGGAGCTAGAGTCC
AGGCACAAAGTCCTAACGATGGCCTGGATTTCCAGGACAACCAGGTAGTAAGTAAGCTTGTAGA
GCCCCCCCACGGGTGTCATGGAAGTGTGGTCGCCTTCCACAGCCCCACCTCTAAGCCAGATGCC
TTAGACATGTGGCTGCTTTATACCCACCCTACGGACTCCAGGAATAGAACCAACCTGGGCGTGT
ACCTCAACCAGACGCCACTAGATCCCACAGCCTGGTCAGAGCCCACCCTGCTAGCCACGGGCAC
CTGTGCCTACTCAGACTTGCAGAATATGGGGCGTGGCCCTGATGGGTCCCCACAGTTTGGGTGC
CTGTATGAATCAGGTAACTATGACGAGATCATTTTCCTCATGTTCACCCTGAAGCAAGCTTTTC
CCACAGTACATGGTGCTCAGTGACCTCATTGCATGTGGCTTCCAAAGGGCTTCCTGTGCTTCAG
AACACCCGTCTCTCTTTCCTTCCAGCATCCTCTGGACTCTTGAATCCAGCTCTTGGGTCTGTTC
CTTGGGAGTATACAGAGAGTTTGGTCTCTTGACTCTTAGCAAGTTTTGTTCTTTCAGCCTCCGA
AAGTGGGTTCTATTTTCAGCCCAGAAATCAAAGGAGCCTGACTTTCCTCAGCCTGTATGTATAA
AGGCTGCCACTCTGCATGTTGGCTGTCACTATGTTAGCTTAACCTGCCTGTTTCCCCATGCCTA
GTTTTTGGATGAATATTAATAAATTAATTATCCTACTCAGCCTA

hide sequence

RefSeq Acc Id:

XM_017596302 ⟹ XP_017451791

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	95,711,951 - 95,715,209 (+)	NCBI
mRatBN7.2	9	88,264,082 - 88,267,356 (+)	NCBI
Rnor_6.0	9	94,721,619 - 94,724,903 (+)	NCBI

Sequence:

show sequence

CTTTGGAACAGCTTTCTAGGGCTCTGGAGTTATAAAAAGGCTCCCACGTGTCATTCCCTGACAG
TCGGACAGCTGCAGAGAGCCACTTAGCAAGCTCCTCTACTCTCCTCAGGGTTAGCAGCTGAAGA
TCTCAGGCCCATGGAGACCTGCCCCGTCCTCCAGAAAGAGACGCTGTTCCACACAGAAGTCTAT
GCTTACAGAATCCCTGCTCTGCTCTACCTGAAGAAGCAGAAGACCCTGCTGGCCTTTGCAGAAA
AGCGAGCCAGCAGGACGGATGAGCATGCTGAGTTGATTGTCCTGCGAAGAGGGAGCTACAATGG
AGCCACCAACCATGTCAAGTGGCAACCTGAGGAAGTGGTGACCCAAGCCCAGCTGGAGGGCCAC
CGCTCCATGAATCCATGTCCCTTGTATGACAAGCAAACAAAGACCCTCTTCCTTTTCTTCATTG
CTGTCCCTGGGCGTGTATCAGAACAGCATCAGCTCCAAACTAGGGTTAATGTCACACGGCTATG
CCGTGTCACCAGCACCGATTATGGGATGAACTGGAGCCCCGTCCAGGACCTCACAGAGACCACC
ATTGGCAGCACCCACCAGGACTGGGCCACATTTGCTGTGGGTCCAGGGCACTGTCTGCAGCTGC
GGAACAGAGCTGGGAGCCTGCTGGTACCTGCTTATGCCTACCAGAAGCTGCACCCTGTCCATAA
ACCTACCCCCTTTGCCTTCTGCTTCATCAGCCTTGACCACGGGCACACGTGGGAACTAGGGAAC
TTTGTGTCTGAGAACTCACTGGAGTGTCAGGTGGCTGAGGTTGGCACTGGTGCTCATAGGGTGG
TATATCTCAATGCTAGGAGCTTCATAGGAGCTAGAGTCCAGGCACAAAGTCCTAACGATGGCCT
GGATTTCCAGGACAACCAGGTAGTAAGTAAGCTTGTAGAGCCCCCCCACGGGTGTCATGGAAGT
GTGGTCGCCTTCCACAGCCCCACCTCTAAGCCAGATGCCTTAGACATGTGGCTGCTTTATACCC
ACCCTACGGACTCCAGGAATAGAACCAACCTGGGCGTGTACCTCAACCAGACGCCACTAGATCC
CACAGCCTGGTCAGAGCCCACCCTGCTAGCCACGGGCACCTGTGCCTACTCAGACTTGCAGAAT
ATGGGGCGTGGCCCTGATGGGTCCCCACAGTTTGGGTGCCTGTATGAATCAGGTAACTATGACG
AGATCATTTTCCTCATGTTCACCCTGAAGCAAGCTTTTCCCACAGTACATGGTGCTCAGTGACC
TCATTGCATGTGGCTTCCAAAGGGCTTCCTGTGCTTCAGAACACCCGTCTCTCTTTCCTTCCAG
CATCCTCTGGACTCTTGAATCCAGCTCTTGGGTCTGTTCCTTGGGAGTATACAGAGAGTTTGGT
CTCTTGACTCTTAGCAAGTTTTGTTCTTTCAGCCTCCGAAAGTGGGTTCTATTTTCAGCCCAGA
AATCAAAGGAGCCTGACTTTCCTCAGCCTGTATGTATAAAGGCTGCCACTCTGCATGTTGGCTG
TCACTATGTTAGCTTAACCTGCCTGTTTCCCCATGCCTAGTTTTTGGATGAATATTAATAAATT
AATTATCCTACTCAGCCTA

hide sequence

RefSeq Acc Id:

XM_039083108 ⟹ XP_038939036

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	95,667,269 - 95,715,209 (+)	NCBI
mRatBN7.2	9	88,219,407 - 88,267,356 (+)	NCBI

RefSeq Acc Id:

XM_039083109 ⟹ XP_038939037

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	95,679,798 - 95,715,209 (+)	NCBI
mRatBN7.2	9	88,231,945 - 88,267,356 (+)	NCBI

RefSeq Acc Id:

XM_039083110 ⟹ XP_038939038

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	95,666,338 - 95,715,209 (+)	NCBI
mRatBN7.2	9	88,218,494 - 88,267,356 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_058826	(Get FASTA)	NCBI Sequence Viewer
	XP_006245423	(Get FASTA)	NCBI Sequence Viewer
	XP_006245424	(Get FASTA)	NCBI Sequence Viewer
	XP_017451791	(Get FASTA)	NCBI Sequence Viewer
	XP_038939036	(Get FASTA)	NCBI Sequence Viewer
	XP_038939037	(Get FASTA)	NCBI Sequence Viewer
	XP_038939038	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH91154	(Get FASTA)	NCBI Sequence Viewer
	BAA03805	(Get FASTA)	NCBI Sequence Viewer
	BAA09169	(Get FASTA)	NCBI Sequence Viewer
	EDL75643	(Get FASTA)	NCBI Sequence Viewer
	EDL75644	(Get FASTA)	NCBI Sequence Viewer
	EDL75645	(Get FASTA)	NCBI Sequence Viewer
	EDL75646	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000022818
	ENSRNOP00000022818.2
	ENSRNOP00000071166.2
	ENSRNOP00000087714.1
GenBank Protein	Q64627	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_058826 ⟸ NM_017130

- UniProtKB:

Q5BK97 (UniProtKB/TrEMBL), A6JWN5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

METCPVLQKETLFHTEVYAYRIPALLYLKKQKTLLAFAEKRASRTDEHAELIVLRRGSYNGATN
HVKWQPEEVVTQAQLEGHRSMNPCPLYDKQTKTLFLFFIAVPGRVSEQHQLQTRVNVTRLCRVT
STDYGMNWSPVQDLTETTIGSTHQDWATFAVGPGHCLQLRNRAGSLLVPAYAYQKLHPVHKPTP
FAFCFISLDHGHTWELGNFVSENSLECQVAEVGTGAHRVVYLNARSFIGARVQAQSPNDGLDFQ
DNQVVSKLVEPPHGCHGSVVAFHSPTSKPDALDMWLLYTHPTDSRNRTNLGVYLNQTPLDPTAW
SEPTLLATGTCAYSDLQNMGRGPDGSPQFGCLYESGNYDEIIFLMFTLKQAFPTVHGAQ

hide sequence

RefSeq Acc Id:	XP_006245424 ⟸ XM_006245362
- Peptide Label:	isoform X1
- UniProtKB:	Q5BK97 (UniProtKB/TrEMBL), A6JWN5 (UniProtKB/TrEMBL)
- Sequence:	show sequence METCPVLQKETLFHTEVYAYRIPALLYLKKQKTLLAFAEKRASRTDEHAELIVLRRGSYNGATN HVKWQPEEVVTQAQLEGHRSMNPCPLYDKQTKTLFLFFIAVPGRVSEQHQLQTRVNVTRLCRVT STDYGMNWSPVQDLTETTIGSTHQDWATFAVGPGHCLQLRNRAGSLLVPAYAYQKLHPVHKPTP FAFCFISLDHGHTWELGNFVSENSLECQVAEVGTGAHRVVYLNARSFIGARVQAQSPNDGLDFQ DNQVVSKLVEPPHGCHGSVVAFHSPTSKPDALDMWLLYTHPTDSRNRTNLGVYLNQTPLDPTAW SEPTLLATGTCAYSDLQNMGRGPDGSPQFGCLYESGNYDEIIFLMFTLKQAFPTVHGAQ hide sequence

RefSeq Acc Id:	XP_006245423 ⟸ XM_006245361
- Peptide Label:	isoform X1
- UniProtKB:	Q5BK97 (UniProtKB/TrEMBL), A6JWN5 (UniProtKB/TrEMBL)
- Sequence:	show sequence METCPVLQKETLFHTEVYAYRIPALLYLKKQKTLLAFAEKRASRTDEHAELIVLRRGSYNGATN HVKWQPEEVVTQAQLEGHRSMNPCPLYDKQTKTLFLFFIAVPGRVSEQHQLQTRVNVTRLCRVT STDYGMNWSPVQDLTETTIGSTHQDWATFAVGPGHCLQLRNRAGSLLVPAYAYQKLHPVHKPTP FAFCFISLDHGHTWELGNFVSENSLECQVAEVGTGAHRVVYLNARSFIGARVQAQSPNDGLDFQ DNQVVSKLVEPPHGCHGSVVAFHSPTSKPDALDMWLLYTHPTDSRNRTNLGVYLNQTPLDPTAW SEPTLLATGTCAYSDLQNMGRGPDGSPQFGCLYESGNYDEIIFLMFTLKQAFPTVHGAQ hide sequence

RefSeq Acc Id:	XP_017451791 ⟸ XM_017596302
- Peptide Label:	isoform X1
- UniProtKB:	Q5BK97 (UniProtKB/TrEMBL), A6JWN5 (UniProtKB/TrEMBL)
- Sequence:	show sequence METCPVLQKETLFHTEVYAYRIPALLYLKKQKTLLAFAEKRASRTDEHAELIVLRRGSYNGATN HVKWQPEEVVTQAQLEGHRSMNPCPLYDKQTKTLFLFFIAVPGRVSEQHQLQTRVNVTRLCRVT STDYGMNWSPVQDLTETTIGSTHQDWATFAVGPGHCLQLRNRAGSLLVPAYAYQKLHPVHKPTP FAFCFISLDHGHTWELGNFVSENSLECQVAEVGTGAHRVVYLNARSFIGARVQAQSPNDGLDFQ DNQVVSKLVEPPHGCHGSVVAFHSPTSKPDALDMWLLYTHPTDSRNRTNLGVYLNQTPLDPTAW SEPTLLATGTCAYSDLQNMGRGPDGSPQFGCLYESGNYDEIIFLMFTLKQAFPTVHGAQ hide sequence

RefSeq Acc Id:

ENSRNOP00000071166 ⟸ ENSRNOT00000080930

RefSeq Acc Id:

ENSRNOP00000022818 ⟸ ENSRNOT00000022818

RefSeq Acc Id:	XP_038939038 ⟸ XM_039083110
- Peptide Label:	isoform X1
- UniProtKB:	Q5BK97 (UniProtKB/TrEMBL), A6JWN5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038939036 ⟸ XM_039083108
- Peptide Label:	isoform X1
- UniProtKB:	Q5BK97 (UniProtKB/TrEMBL), A6JWN5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038939037 ⟸ XM_039083109
- Peptide Label:	isoform X1
- UniProtKB:	Q5BK97 (UniProtKB/TrEMBL), A6JWN5 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000087714 ⟸ ENSRNOT00000096067

Protein Domains

Sialidase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q64627-F1-model_v2	AlphaFold	Q64627	1-379	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696838

Promoter ID:

EPDNEW_R7362

Type:

initiation region

Name:

Neu2_1

Description:

neuraminidase 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	94,721,681 - 94,721,741	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:3164	AgrOrtholog
BioCyc Gene	G2FUF-26839	BioCyc
Ensembl Genes	ENSRNOG00000016962	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000022818	ENTREZGENE
	ENSRNOT00000022818.5	UniProtKB/TrEMBL
	ENSRNOT00000080930.2	UniProtKB/TrEMBL
	ENSRNOT00000096067.1	UniProtKB/TrEMBL
Gene3D-CATH	2.120.10.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7323285	IMAGE-MGC_LOAD
InterPro	Sialidase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Sialidase_fam	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Sialidase_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:29204	UniProtKB/TrEMBL
MGC_CLONE	MGC:108717	IMAGE-MGC_LOAD
NCBI Gene	29204	ENTREZGENE
PANTHER	PTHR10628	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR10628:SF6	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	BNR_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB	NEU2	RGD
PhenoGen	Neu2	PhenoGen
RatGTEx	ENSRNOG00000016962	RatGTEx
Superfamily-SCOP	SSF50939	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2JZS7_RAT	UniProtKB/TrEMBL
	A0A8I6A7R8_RAT	UniProtKB/TrEMBL
	A6JWN5	ENTREZGENE, UniProtKB/TrEMBL
	NEUR2_RAT	UniProtKB/Swiss-Prot
	Q5BK97	ENTREZGENE, UniProtKB/TrEMBL
	Q64627	ENTREZGENE
UniProt Secondary	Q63705	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-04-19	Neu2	neuraminidase 2	Neu2	sialidase 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-04-18	Neu2	sialidase 2	Neu2	sialidase 2 (cytosolic sialidase)	Name changed	629549	APPROVED
2008-09-25	Neu2	sialidase 2 (cytosolic sialidase)	Neu2	neuraminidase 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-06-10	Neu2	neuraminidase 2			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in skeletal muscle	69901
gene_protein	379 amino acids	69901

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)