Gene: Smad2 (SMAD family member 2) Rattus norvegicus
Symbol: Smad2
Name: SMAD family member 2
Description: ENCODES a protein that exhibits transcription factor binding; activating transcription factor binding (ortholog); chromatin binding (ortholog); INVOLVED IN adrenal gland development; negative regulation of cell proliferation; positive regulation of transcription by RNA polymerase II; PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; altered transforming growth factor-beta Smad dependent signaling pathway; colorectal cancer pathway; ASSOCIATED WITH hepatocellular carcinoma; Hypoglossal Nerve Injuries; myocardial infarction; FOUND IN cytoplasm; nucleus; protein-containing complex; INTERACTS WITH 2-acetamidofluorene; 2-amino-2-deoxy-D-galactopyranose; 2-methoxyethanol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MAD (mothers against decapentaplegic Drosophila) homolog 2; MAD (mothers against decapentaplegic, Drosophila) homolog 2; MAD homolog 2; MAD homolog 2 (Drosophila); mad-related protein 2; Madh2; MGC156656; mothers against decapentaplegic homolog 2; mothers against DPP homolog 2; SMAD 2
Homo sapiens (human) : SMAD2 (SMAD family member 2)  HGNC  Alliance
Mus musculus (house mouse) : Smad2 (SMAD family member 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smad2 (SMAD family member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SMAD2 (SMAD family member 2)
Canis lupus familiaris (dog) : SMAD2 (SMAD family member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smad2 (SMAD family member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01872,550,107 - 72,612,078 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01871,672,879 - 71,735,128 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41873,180,520 - 73,241,707 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11873,253,792 - 73,314,980 (+)NCBI
Celera1868,381,756 - 68,443,610 (+)NCBICelera
Cytogenetic Map18q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Smad2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3031
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-06-05
Status: ACTIVE