Gene: Kras (KRAS proto-oncogene, GTPase) Rattus norvegicus
Symbol: Kras
Name: KRAS proto-oncogene, GTPase
Description: ENCODES a protein that exhibits GDP binding; GMP binding; LRR domain binding; INVOLVED IN cytokine-mediated signaling pathway; female pregnancy; liver development; PARTICIPATES IN the extracellular signal-regulated Raf/Mek/Erk signaling pathway; altered extracellular signal-regulated Raf/Mek/Erk signaling pathway; endometrial cancer pathway; ASSOCIATED WITH bronchiolo-alveolar adenocarcinoma; Endometrial Neoplasms; hepatocellular adenoma; FOUND IN membrane raft; mitochondrion; cytoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,4-dinitrotoluene; 2-trans,6-trans-farnesyl diphosphate
Type: protein-coding
Also known as: c-K-ras; c-K-ras2 protein; c-Ki-ras; c-Kirsten-ras proto-oncogene; GTPase KRas; K-Ras 2; ki-Ras; Kirsten rat sarcoma viral oncogene; Kirsten rat sarcoma viral oncogene homolog; Kirsten rat sarcoma viral oncogene homologue 2 (active); Kras2; p21; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Homo sapiens (human) : KRAS (KRAS proto-oncogene, GTPase)  HGNC  Alliance
Mus musculus (house mouse) : Kras (Kirsten rat sarcoma viral oncogene homolog)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kras (KRAS proto-oncogene, GTPase)
Pan paniscus (bonobo/pygmy chimpanzee) : KRAS (KRAS proto-oncogene, GTPase)
Canis lupus familiaris (dog) : KRAS (KRAS proto-oncogene, GTPase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kras (KRAS proto-oncogene, GTPase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04179,482,562 - 179,515,483 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04243,667,912 - 243,696,325 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44182,869,242 - 182,895,106 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14183,114,365 - 183,140,230 (-)NCBI
Celera4166,708,846 - 166,734,692 (-)NCBICelera
Cytogenetic Map4q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Kras
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2981
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-06-05
Status: ACTIVE