Gene: Itpr1 (inositol 1,4,5-trisphosphate receptor, type 1) Rattus norvegicus
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Symbol: Itpr1
Name: inositol 1,4,5-trisphosphate receptor, type 1
Description: ENCODES a protein that exhibits identical protein binding; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; protein C-terminus binding; INVOLVED IN cellular response to cAMP; cellular response to hypoxia; dendrite development; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH asthma; cardiac arrest; Huntington's disease; FOUND IN cytoplasm; dendrite; endoplasmic reticulum membrane; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE; 17alpha-ethynylestradiol
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: I145TR; inositol 1,4,5-triphosphate receptor 1; inositol 1,4,5-triphosphate receptor type 1; inositol 1,4,5-triphosphate receptor, type 1; inositol 1,4,5-trisphosphate receptor type 1; inositol 145-triphosphate receptor type 1; InsP3R; InsP3R1; IP-3-R; IP3 receptor; IP3R 1; IP3R1; P400; type 1 inositol 1,4,5-trisphosphate receptor; type 1 InsP3 receptor
Orthologs:
Homo sapiens (human) : ITPR1 (inositol 1,4,5-trisphosphate receptor type 1)  HGNC  Alliance
Mus musculus (house mouse) : Itpr1 (inositol 1,4,5-trisphosphate receptor 1)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : ITPR1 (inositol 1,4,5-trisphosphate receptor type 1)
Canis lupus familiaris (dog) : ITPR1 (inositol 1,4,5-trisphosphate receptor type 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itpr1 (inositol 1,4,5-trisphosphate receptor type 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04140,247,297 - 140,580,749 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04204,714,729 - 205,047,901 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44143,705,360 - 144,030,051NCBIRGSC3.4rn4RGSC3.4
Celera4129,839,611 - 130,162,657 (+)NCBICelera
Cytogenetic Map4q41NCBI
RH 3.4 Map4 RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Itpr1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2933
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-10-16
Status: ACTIVE