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Gene: Hras (HRas proto-oncogene, GTPase) Rattus norvegicus
Symbol: Hras
Name: HRas proto-oncogene, GTPase
Description: Predicted to have GTPase activity; protein C-terminus binding activity; and purine ribonucleoside binding activity. Involved in several processes, including cellular senescence; positive regulation of intracellular signal transduction; and protein heterooligomerization. Localizes to the intracellular membrane-bounded organelle and plasma membrane. Used to study diabetic retinopathy. Human ortholog(s) of this gene implicated in several diseases, including Costello syndrome; autistic disorder; carcinoma (multiple); epidermal nevus; and obsessive-compulsive disorder. Orthologous to human HRAS (HRas proto-oncogene, GTPase); PARTICIPATES IN adenosine signaling pathway; endothelin signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH (S)-nicotine; 1,2-dichlorobenzene; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: c-H-ras; GTPase HRas; H-Ras-1; Harvey ras1 protein; Harvey rat sarcoma viral (v-Ha-ras) oncogene homolog; Harvey rat sarcoma virus oncogene; HRAS1; p21ras; transforming protein p21
Homo sapiens (human) : HRAS (HRas proto-oncogene, GTPase)  HGNC  Alliance
Mus musculus (house mouse) : Hras (Harvey rat sarcoma virus oncogene)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hras (HRas proto-oncogene, GTPase)
Pan paniscus (bonobo/pygmy chimpanzee) : HRAS (HRas proto-oncogene, GTPase)
Canis lupus familiaris (dog) : HRAS (HRas proto-oncogene, GTPase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hras (HRas proto-oncogene, GTPase)
Sus scrofa (pig) : HRAS (HRas proto-oncogene, GTPase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01214,178,404 - 214,181,841 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01221,095,943 - 221,099,362 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41201,385,705 - 201,388,987 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11201,540,000 - 201,542,640 (-)NCBI
Celera1193,930,281 - 193,933,583 (-)NCBICelera
Cytogenetic Map1q41NCBI
RH 3.4 Map11437.21RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)