Gene: Gucy1b1 (guanylate cyclase 1 soluble subunit beta 1) Rattus norvegicus
Symbol: Gucy1b1
Name: guanylate cyclase 1 soluble subunit beta 1
Description: ENCODES a protein that exhibits adenylate cyclase activity; cytidylate cyclase activity; heme binding; INVOLVED IN cellular response to nitric oxide (ortholog); cGMP biosynthetic process (ortholog); cGMP-mediated signaling (ortholog); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Creutzfeldt-Jakob Disease, Sporadic (ortholog); FOUND IN glutamatergic synapse; guanylate cyclase complex, soluble; presynaptic active zone; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 17beta-estradiol
Type: protein-coding
Also known as: GCS-beta-1; GCS-beta-3; guanylate cyclase 1 soluble beta 3; guanylate cyclase 1 soluble subunit beta 3; guanylate cyclase 1, soluble, beta 3; Guanylate cyclase soluble beta 1 (GTP pyrophosphate - lyase); Guanylate cyclase soluble beta 1 (GTP pyrophosphate - lyase) see also D2Mgh17; guanylate cyclase soluble subunit beta-1; guanylate cyclase soluble subunit beta-3; guanylate cyclase, soluble, beta 1; Gucy1b3; MGC93604; SGC; soluble guanylate cyclase small subunit; soluble guanylyl cyclase beta 1 subunit
Homo sapiens (human) : GUCY1B1 (guanylate cyclase 1 soluble subunit beta 1)  HGNC  Alliance
Mus musculus (house mouse) : Gucy1b1 (guanylate cyclase 1, soluble, beta 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gucy1b1 (guanylate cyclase 1 soluble subunit beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GUCY1B1 (guanylate cyclase 1 soluble subunit beta 1)
Canis lupus familiaris (dog) : GUCY1B1 (guanylate cyclase 1 soluble subunit beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gucy1b1 (guanylate cyclase 1 soluble subunit beta 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02180,976,939 - 181,026,001 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02200,384,721 - 200,433,787 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42173,683,153 - 173,735,298 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12173,633,259 - 173,685,404 (-)NCBI
Celera2161,378,505 - 161,428,991 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gucy1b1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2769
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-10-09
Status: ACTIVE