Gene: Gadd45a (growth arrest and DNA-damage-inducible, alpha) Rattus norvegicus
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Symbol: Gadd45a
Name: growth arrest and DNA-damage-inducible, alpha
Description: ENCODES a protein that exhibits kinase binding (ortholog); protein heterodimerization activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN G2/M transition of mitotic cell cycle; activation of MAPKKK activity (ortholog); cellular response to ionizing radiation (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; cell cycle pathway, mitotic; mitogen activated protein kinase signaling pathway; ASSOCIATED WITH Arthritis, Juvenile (ortholog); Chemical and Drug Induced Liver Injury (ortholog); Chloracne (ortholog); FOUND IN cytoplasm (ortholog); nuclear speck (ortholog); nucleus (ortholog); INTERACTS WITH (+)-alpha-tocopherol; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; (S)-colchicine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DDIT-1; Ddit1; DNA damage-inducible transcript 1 protein; DNA-damage-inducible transcript 1; Gadd45; growth arrest and DNA damage-inducible protein GADD45 alpha; growth arrest and DNA-damage-inducible 45 alpha; Growth arrest and DNA-damage-inducible protein; growth arrest and DNA-damage-inducible protein GADD45 alpha
Orthologs:
Homo sapiens (human) : GADD45A (growth arrest and DNA damage inducible alpha)  HGNC  AGR
Mus musculus (house mouse) : Gadd45a (growth arrest and DNA-damage-inducible 45 alpha)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Gadd45a (growth arrest and DNA damage inducible alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : GADD45A (growth arrest and DNA damage inducible alpha)
Canis lupus familiaris (dog) : GADD45A (growth arrest and DNA damage inducible alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gadd45a (growth arrest and DNA damage inducible alpha)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0497,782,512 - 97,784,814 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04162,568,472 - 162,570,774 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4496,649,941 - 96,652,243 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1496,894,423 - 96,896,724 (-)NCBI
Celera490,851,517 - 90,853,819 (-)NCBICelera
Cytogenetic Map4q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gadd45a
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2654
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE