Gene: F2r (coagulation factor II (thrombin) receptor) Rattus norvegicus
Analyze
Symbol: F2r
Name: coagulation factor II (thrombin) receptor
Description: ENCODES a protein that exhibits G-protein alpha-subunit binding (ortholog); G-protein beta-subunit binding (ortholog); G-protein coupled receptor activity (ortholog); INVOLVED IN activation of MAPKK activity; establishment of synaptic specificity at neuromuscular junction; G-protein coupled receptor signaling pathway; PARTICIPATES IN G protein mediated signaling pathway; protease mediated signaling via protease-activated receptor 1; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH abnormal nociception after inflammation; ASSOCIATED WITH brain edema; brain ischemia; Hyperalgesia; FOUND IN neuromuscular junction; plasma membrane; postsynaptic membrane; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: coagulation factor II receptor; MGC93622; PAR-1; Par1; protease-activated receptor 1; proteinase-activated receptor 1; Thrombin receptor; TRGPC
Orthologs:
Homo sapiens (human) : F2R (coagulation factor II thrombin receptor)  HGNC  Alliance
Mus musculus (house mouse) : F2r (coagulation factor II (thrombin) receptor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : F2r (coagulation factor II thrombin receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : F2R (coagulation factor II thrombin receptor)
Canis lupus familiaris (dog) : F2R (coagulation factor II thrombin receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : F2r (coagulation factor II thrombin receptor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0226,118,760 - 26,135,340 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0245,254,489 - 45,257,761 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4225,985,800 - 25,989,072 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1225,906,181 - 25,909,441 (-)NCBI
Celera222,933,182 - 22,949,696 (-)NCBICelera
Cytogenetic Map2q12NCBI
RH 3.4 Map213.3RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on F2r
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2586
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-08-08
Status: ACTIVE