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Gene: Efnb3 (ephrin B3) Rattus norvegicus
Symbol: Efnb3
Name: ephrin B3
RGD ID: 2541
Description: Predicted to have ephrin receptor binding activity. Predicted to be involved in several processes, including adult walking behavior; generation of neurons; and trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission. Localizes to glutamatergic synapse and integral component of postsynaptic density membrane. Orthologous to human EFNB3 (ephrin B3); PARTICIPATES IN altered ephrin - ephrin receptor bidirectional signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ELK-L3; ephrin ligand B3; ephrin-B3; LOC360546; RGD1565678; similar to m-ephrin-B3
Homo sapiens (human) : EFNB3 (ephrin B3)  HGNC  Alliance
Mus musculus (house mouse) : Efnb3 (ephrin B3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Efnb3 (ephrin B3)
Pan paniscus (bonobo/pygmy chimpanzee) : EFNB3 (ephrin B3)
Canis lupus familiaris (dog) : EFNB3 (ephrin B3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Efnb3 (ephrin B3)
Sus scrofa (pig) : EFNB3 (ephrin B3)
Chlorocebus sabaeus (African green monkey) : EFNB3 (ephrin B3)
Heterocephalus glaber (naked mole-rat) : Efnb3 (ephrin B3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01056,161,431 - 56,168,819 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1056,161,432 - 56,167,426 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01055,906,788 - 55,912,782 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,373,322 - 56,379,316 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1053,428,729 - 53,434,697 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Efnb3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2541
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.