Gene: Dyrk1a (dual specificity tyrosine phosphorylation regulated kinase 1A) Rattus norvegicus
Symbol: Dyrk1a
Name: dual specificity tyrosine phosphorylation regulated kinase 1A
Description: ENCODES a protein that exhibits protein kinase activity; protein serine/threonine kinase activity; protein tyrosine kinase activity; INVOLVED IN peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; peptidyl-tyrosine phosphorylation; ASSOCIATED WITH autosomal dominant non-syndromic intellectual disability 7 (ortholog); Down syndrome (ortholog); enophthalmos (ortholog); FOUND IN nuclear speck; nucleus; actin filament (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,4-dinitrotoluene; 2,6-dinitrotoluene
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dual specificity tyrosine-phosphorylation-regulated kinase 1A; Dual Specificity Yak1-related kinase; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; Dyrk; MNBH; protein kinase minibrain homolog; PSK47; RP86
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01134,858,339 - 34,958,733 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01138,453,019 - 38,550,512 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41134,879,733 - 34,970,998 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11134,935,975 - 35,027,241 (+)NCBI
Celera1134,444,072 - 34,535,020 (-)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Dyrk1a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2528
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE