Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | Crmp1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of CRMP1 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | Crmp1 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of CRMP1 mRNA] | CTD | PMID:22206623 | 17beta-estradiol | decreases phosphorylation | ISO | CRMP1 (Homo sapiens) | 6480464 | Estradiol results in decreased phosphorylation of CRMP1 protein | CTD | PMID:27026707 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CRMP1 mRNA | CTD | PMID:32741896 | 17beta-estradiol 3-benzoate | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CRMP1 mRNA | CTD | PMID:32741896 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Crmp1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of CRMP1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CRMP1 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Crmp1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CRMP1 mRNA | CTD | PMID:33956508 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CRMP1 mRNA | CTD | PMID:32109520 and PMID:33387578 | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:19954255 | 4,4'-sulfonyldiphenol | decreases expression | ISO | Crmp1 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of CRMP1 mRNA | CTD | PMID:30951980 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of CRMP1 mRNA | CTD | PMID:24780913 | aflatoxin B1 | increases expression | ISO | CRMP1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of CRMP1 mRNA | CTD | PMID:22100608 | Aflatoxin B2 alpha | affects methylation | ISO | CRMP1 (Homo sapiens) | 6480464 | aflatoxin B2 affects the methylation of CRMP1 intron | CTD | PMID:30157460 | aldehydo-D-glucose | multiple interactions | EXP | | 6480464 | CRMP1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] | CTD | PMID:21124846 | all-trans-retinoic acid | decreases expression | ISO | CRMP1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of CRMP1 mRNA | CTD | PMID:21934132 | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of CRMP1 mRNA | CTD | PMID:30779732 | aripiprazole | increases expression | EXP | | 6480464 | Aripiprazole results in increased expression of CRMP1 mRNA | CTD | PMID:17868501 | aristolochic acid A | increases expression | ISO | CRMP1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of CRMP1 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | increases methylation | ISO | CRMP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of CRMP1 exon and Benzo(a)pyrene results in increased methylation of CRMP1 promoter | CTD | PMID:27901495 | benzo[e]pyrene | increases methylation | ISO | CRMP1 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of CRMP1 intron | CTD | PMID:30157460 | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CRMP1 mRNA | CTD | PMID:31199487 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of CRMP1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Crmp1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of CRMP1 mRNA | CTD | PMID:32156529 | bisphenol A | decreases expression | ISO | CRMP1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of CRMP1 protein | CTD | PMID:37567409 | bisphenol A | decreases methylation | ISO | CRMP1 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of CRMP1 gene | CTD | PMID:31601247 | bisphenol A | multiple interactions | ISO | CRMP1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of CRMP1 gene | CTD | PMID:31601247 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of CRMP1 mRNA | CTD | PMID:30816183 and PMID:34947998 | bromobenzene | affects expression | EXP | | 6480464 | bromobenzene affects the expression of CRMP1 mRNA | CTD | PMID:32479839 | butanal | increases expression | ISO | CRMP1 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of CRMP1 mRNA | CTD | PMID:26079696 | Butylbenzyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CRMP1 mRNA | CTD | PMID:31199487 | cadmium dichloride | increases expression | ISO | Crmp1 (Mus musculus) | 6480464 | Cadmium Chloride results in increased expression of CRMP1 mRNA | CTD | PMID:24982889 | carbon nanotube | affects expression | ISO | Crmp1 (Mus musculus) | 6480464 | Nanotubes and Carbon affects the expression of CRMP1 protein | CTD | PMID:21135415 | CGP 52608 | multiple interactions | ISO | CRMP1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to CRMP1 gene] | CTD | PMID:28238834 | chlordecone | increases expression | ISO | Crmp1 (Mus musculus) | 6480464 | Chlordecone results in increased expression of CRMP1 mRNA | CTD | PMID:29980752 | chlorpyrifos | increases expression | ISO | Crmp1 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of CRMP1 mRNA | CTD | PMID:32715474 | cisplatin | increases phosphorylation | ISO | Crmp1 (Mus musculus) | 6480464 | Cisplatin results in increased phosphorylation of CRMP1 protein | CTD | PMID:22006019 | D-glucose | multiple interactions | EXP | | 6480464 | CRMP1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] | CTD | PMID:21124846 | dibutyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CRMP1 mRNA | CTD | PMID:31199487 | diethyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CRMP1 mRNA | CTD | PMID:31199487 | diisobutyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CRMP1 mRNA | CTD | PMID:31199487 | diisononyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CRMP1 mRNA | CTD | PMID:31199487 | dioxygen | multiple interactions | EXP | | 6480464 | CRMP1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] | CTD | PMID:21124846 | dioxygen | increases expression | ISO | Crmp1 (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of CRMP1 protein | CTD | PMID:25937538 | disodium selenite | decreases expression | ISO | CRMP1 (Homo sapiens) | 6480464 | Sodium Selenite results in decreased expression of CRMP1 mRNA | CTD | PMID:18175754 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of CRMP1 mRNA | CTD | PMID:29391264 | epoxiconazole | increases expression | ISO | Crmp1 (Mus musculus) | 6480464 | epoxiconazole results in increased expression of CRMP1 mRNA | CTD | PMID:35436446 | ethanol | affects splicing | ISO | Crmp1 (Mus musculus) | 6480464 | Ethanol affects the splicing of CRMP1 mRNA | CTD | PMID:30319688 | ethanol | affects expression | ISO | Crmp1 (Mus musculus) | 6480464 | Ethanol affects the expression of CRMP1 mRNA | CTD | PMID:30319688 | folic acid | decreases expression | ISO | Crmp1 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of CRMP1 mRNA | CTD | PMID:25629700 | folic acid | multiple interactions | ISO | Crmp1 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of CRMP1 mRNA] | CTD | PMID:22206623 | fonofos | increases methylation | ISO | CRMP1 (Homo sapiens) | 6480464 | Fonofos results in increased methylation of CRMP1 promoter | CTD | PMID:22847954 | fulvestrant | multiple interactions | ISO | CRMP1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of CRMP1 gene | CTD | PMID:31601247 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of CRMP1 mRNA | CTD | PMID:33387578 | glucose | multiple interactions | EXP | | 6480464 | CRMP1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] | CTD | PMID:21124846 | ivermectin | decreases expression | ISO | CRMP1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of CRMP1 protein | CTD | PMID:32959892 | methapyrilene | increases methylation | ISO | CRMP1 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of CRMP1 intron | CTD | PMID:30157460 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CRMP1 mRNA | CTD | PMID:20360939 | paracetamol | affects expression | ISO | Crmp1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of CRMP1 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | CRMP1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of CRMP1 mRNA | CTD | PMID:29067470 | parathion | increases methylation | ISO | CRMP1 (Homo sapiens) | 6480464 | Parathion results in increased methylation of CRMP1 promoter | CTD | PMID:22847954 | pentanal | increases expression | ISO | CRMP1 (Homo sapiens) | 6480464 | pentanal results in increased expression of CRMP1 mRNA | CTD | PMID:26079696 | phenethyl caffeate | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CRMP1 mRNA | CTD | PMID:20360939 | pirinixic acid | multiple interactions | ISO | Crmp1 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CRMP1 mRNA | CTD | PMID:19710929 | rotenone | affects expression | ISO | Crmp1 (Mus musculus) | 6480464 | Rotenone affects the expression of CRMP1 mRNA | CTD | PMID:23186747 | SB 431542 | multiple interactions | ISO | CRMP1 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of CRMP1 protein | CTD | PMID:37664457 | selenomethionine | affects expression | ISO | CRMP1 (Homo sapiens) | 6480464 | Selenomethionine affects the expression of CRMP1 mRNA | CTD | PMID:17222674 | silicon dioxide | increases expression | ISO | Crmp1 (Mus musculus) | 6480464 | Silicon Dioxide results in increased expression of CRMP1 mRNA | CTD | PMID:29341224 | sodium arsenite | decreases expression | ISO | CRMP1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of CRMP1 mRNA | CTD | PMID:25879800 | sodium arsenite | affects methylation | ISO | CRMP1 (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of CRMP1 gene | CTD | PMID:28589171 | sunitinib | decreases expression | ISO | CRMP1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of CRMP1 mRNA | CTD | PMID:31533062 | terbufos | increases methylation | ISO | CRMP1 (Homo sapiens) | 6480464 | terbufos results in increased methylation of CRMP1 promoter | CTD | PMID:22847954 | testosterone | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CRMP1 mRNA | CTD | PMID:32741896 | thapsigargin | increases expression | EXP | | 6480464 | Thapsigargin results in increased expression of CRMP1 protein | CTD | PMID:35544339 | urethane | decreases expression | ISO | CRMP1 (Homo sapiens) | 6480464 | Urethane results in decreased expression of CRMP1 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | Crmp1 (Mus musculus) | 6480464 | Valproic Acid affects the expression of CRMP1 mRNA | CTD | PMID:17292431 | valproic acid | affects expression | ISO | CRMP1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of CRMP1 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | CRMP1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of CRMP1 mRNA | CTD | PMID:23179753 and PMID:25192806 | |