Gene: Fbxw7 (F-box and WD repeat domain containing 7) Rattus norvegicus
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Symbol: Fbxw7
Name: F-box and WD repeat domain containing 7
Description: ENCODES a protein that exhibits cyclin binding (ortholog); DNA-binding transcription factor activity (ortholog); identical protein binding (ortholog); INVOLVED IN cellular response to DNA damage stimulus (ortholog); cellular response to UV (ortholog); lung development (ortholog); PARTICIPATES IN Notch signaling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); basal cell carcinoma (ortholog); bladder urothelial carcinoma (ortholog); FOUND IN cytoplasm (ortholog); endoplasmic reticulum (ortholog); Golgi apparatus (ortholog); INTERACTS WITH (-)-demecolcine (ortholog); 17alpha-ethynylestradiol (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase; F-box and WD-40 domain protein 7; F-box/WD repeat-containing protein 7; LOC100360914
Orthologs:
Homo sapiens (human) : FBXW7 (F-box and WD repeat domain containing 7)  HGNC  Alliance
Mus musculus (house mouse) : Fbxw7 (F-box and WD-40 domain protein 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxw7 (F-box and WD repeat domain containing 7)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXW7 (F-box and WD repeat domain containing 7)
Canis lupus familiaris (dog) : FBXW7 (F-box and WD repeat domain containing 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxw7 (F-box and WD repeat domain containing 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02184,230,191 - 184,309,805 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02203,633,724 - 203,708,120 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42176,675,226 - 176,750,737 (+)NCBIRGSC3.4rn4RGSC3.4
Celera2164,144,641 - 164,303,043 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Fbxw7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2321145
Created: 2010-05-05
Species: Rattus norvegicus
Last Modified: 2018-06-05
Status: ACTIVE