Gene: Runx2 (runt-related transcription factor 2) Rattus norvegicus
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Symbol: Runx2
Name: runt-related transcription factor 2
Description: ENCODES a protein that exhibits histone deacetylase binding; transcription factor binding; bHLH transcription factor binding (ortholog); INVOLVED IN cellular response to fibroblast growth factor stimulus; osteoblast differentiation; positive regulation of ossification; PARTICIPATES IN fibroblast growth factor signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH Fractures, Bone; Hyperoxaluria; Ossification, Heterotopic; FOUND IN nucleus; cytoplasm (ortholog); nuclear chromatin (ortholog); INTERACTS WITH (20S)-ginsenoside Rg3; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CBF-alpha-1; Cbfa1; core-binding factor subunit alpha-1; OSF-2; osteoblast-specific transcription factor 2; runt related transcription factor 2
Orthologs:
Homo sapiens (human) : RUNX2 (runt related transcription factor 2)  HGNC  AGR
Mus musculus (house mouse) : Runx2 (runt related transcription factor 2)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Runx2 (runt related transcription factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RUNX2 (runt related transcription factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Runx2 (runt related transcription factor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0918,564,743 - 18,773,092 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0917,448,142 - 17,658,373 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4911,869,234 - 12,025,219 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1911,867,896 - 11,943,304 (+)NCBI
Celera913,904,221 - 14,111,920 (+)NCBICelera
Cytogenetic Map9q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Runx2
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2282
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-11-28
Status: ACTIVE