Gene: Ak4 (adenylate kinase 4) Rattus norvegicus
Symbol: Ak4
Name: adenylate kinase 4
Description: ENCODES a protein that exhibits adenylate kinase activity (ortholog); nucleoside diphosphate kinase activity (ortholog); nucleoside triphosphate adenylate kinase activity (ortholog); INVOLVED IN brain development; liver development; response to drug; PARTICIPATES IN de novo purine biosynthetic pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury; Kidney Tubular Necrosis, Acute; Osteoarthritis (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,2,2-tetramine
Type: protein-coding
Also known as: adenylate kinase 3 alpha-like 1; adenylate kinase 3-like 1; adenylate kinase 3-like 2; adenylate kinase 4, mitochondrial; adenylate kinase isoenzyme 4; adenylate kinase isoenzyme 4, mitochondrial; AK 4; Ak3l1; Ak3l2; ATP-AMP transphosphorylase; GTP:AMP phosphotransferase AK4; GTP:AMP phosphotransferase AK4, mitochondrial; MGC93541
Homo sapiens (human) : AK4 (adenylate kinase 4)  HGNC  Alliance
Mus musculus (house mouse) : Ak4 (adenylate kinase 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ak4 (adenylate kinase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : AK4 (adenylate kinase 4)
Canis lupus familiaris (dog) : AK4 (adenylate kinase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ak4 (adenylate kinase 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05120,250,318 - 120,309,153 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05124,129,933 - 124,189,606 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45122,062,872 - 122,119,335 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15122,068,045 - 122,127,564 (+)NCBI
Celera5114,576,993 - 114,626,919 (+)NCBICelera
Cytogenetic Map5q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ak4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2078
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-04-10
Status: ACTIVE