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Gene: Acly (ATP citrate lyase) Rattus norvegicus
Symbol: Acly
Name: ATP citrate lyase
RGD ID: 2018
Description: Exhibits ATP citrate synthase activity. Involved in acetyl-CoA metabolic process; citrate metabolic process; and fatty acid biosynthetic process. Predicted to localize to cytosol; nucleoplasm; and plasma membrane. Orthologous to human ACLY (ATP citrate lyase); PARTICIPATES IN fatty acid biosynthetic pathway; citric acid cycle pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ACL; ATP-citrate (pro-S-)-lyase; ATP-citrate synthase; citrate cleavage enzyme; Clatp; MGC124629
Homo sapiens (human) : ACLY (ATP citrate lyase)  HGNC  Alliance
Mus musculus (house mouse) : Acly (ATP citrate lyase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acly (ATP citrate lyase)
Pan paniscus (bonobo/pygmy chimpanzee) : ACLY (ATP citrate lyase)
Canis lupus familiaris (dog) : ACLY (ATP citrate lyase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acly (ATP citrate lyase)
Sus scrofa (pig) : ACLY (ATP citrate lyase)
Chlorocebus sabaeus (African green monkey) : ACLY (ATP citrate lyase)
Heterocephalus glaber (naked mole-rat) : Acly (ATP citrate lyase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01088,392,248 - 88,442,845 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1088,392,248 - 88,442,845 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01088,185,495 - 88,237,133 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41089,420,934 - 89,471,398 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11089,435,312 - 89,485,719 (-)NCBI
Celera1084,129,399 - 84,179,946 (-)NCBICelera
Cytogenetic Map10q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Acly
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2018
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.