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Gene: Atm (ATM serine/threonine kinase) Rattus norvegicus
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Symbol: Atm
Name: ATM serine/threonine kinase
Description: Predicted to have kinase activity; protein N-terminus binding activity; and protein dimerization activity. Involved in several processes, including positive regulation of macromolecule metabolic process; positive regulation of neuron apoptotic process; and regulation of microglial cell activation. Localizes to the cytoplasm and nucleus. Predicted to colocalize with the chromosome, telomeric region. Used to study ataxia telangiectasia; disease of cellular proliferation; infertility; leukemia; and lymphoma. Biomarker of pre-malignant neoplasm and status epilepticus. Human ortholog(s) of this gene implicated in Parkinson's disease; ataxia telangiectasia; breast cancer; endometrial cancer; and pancreatic cancer. Orthologous to human ATM (ATM serine/threonine kinase); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; homologous recombination pathway of double-strand break repair; nuclear factor kappa B signaling pathway; INTERACTS WITH 2-amino-2-deoxy-D-galactopyranose; 7,12-dimethyltetraphene; amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Ataxia telangiectasia gene mutated in human beings; ataxia telangiectasia mutated; ataxia telangiectasia mutated homolog; ataxia telangiectasia mutated homolog (human); ataxia telangiectasia mutated homolog (human) (mapped); Atm_mapped; serine-protein kinase ATM
Orthologs:
Homo sapiens (human) : ATM (ATM serine/threonine kinase)  HGNC  Alliance
Mus musculus (house mouse) : Atm (ataxia telangiectasia mutated)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atm (ATM serine/threonine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : ATM (ATM serine/threonine kinase)
Canis lupus familiaris (dog) : ATM (ATM serine/threonine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atm (ATM serine/threonine kinase)
Sus scrofa (pig) : ATM (ATM serine/threonine kinase)
more info ...
Allele / Splice: Atmm1Kyo   Atmem1Kyo  
Genetic Models: F344-Atmm1Kyo F344-Atmem1Kyo
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0858,015,938 - 58,119,973 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl858,015,940 - 58,120,045 (-)Ensembl
Rnor_5.0856,598,503 - 56,703,115 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4856,894,746 - 56,996,565 (-)NCBIRGSC3.4rn4RGSC3.4
Celera853,321,802 - 53,423,212 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model