Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-alpha-phellandrene | decreases expression | ISO | PTPMT1 (Homo sapiens) | 6480464 | alpha phellandrene results in decreased expression of PTPMT1 mRNA | CTD | PMID:25075043 | 1,2-dimethylhydrazine | decreases expression | ISO | Ptpmt1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of PTPMT1 mRNA | CTD | PMID:22206623 | 2,2',4,4',5,5'-hexachlorobiphenyl | affects expression | ISO | Ptpmt1 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:24680724 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PTPMT1 mRNA | CTD | PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PTPMT1 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ptpmt1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PTPMT1 mRNA | CTD | PMID:24680724 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of PTPMT1 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of PTPMT1 mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | decreases expression | ISO | PTPMT1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of PTPMT1 mRNA | CTD | PMID:30851411 | 3,4-dihydrocoumarin | decreases expression | ISO | Ptpmt1 (Mus musculus) | 6480464 | 3 and 4-dihydrocoumarin results in decreased expression of PTPMT1 mRNA | CTD | PMID:22016648 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | PTPMT1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of PTPMT1 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | PTPMT1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of PTPMT1 mRNA | CTD | PMID:28628672 | acrylamide | decreases expression | ISO | PTPMT1 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of PTPMT1 mRNA | CTD | PMID:32763439 | all-trans-retinoic acid | increases expression | ISO | PTPMT1 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of PTPMT1 mRNA | CTD | PMID:21934132 | all-trans-retinoic acid | decreases expression | ISO | PTPMT1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of PTPMT1 mRNA | CTD | PMID:33167477 | alpha-phellandrene | decreases expression | ISO | PTPMT1 (Homo sapiens) | 6480464 | alpha phellandrene results in decreased expression of PTPMT1 mRNA | CTD | PMID:25075043 | aniline | increases expression | ISO | Ptpmt1 (Mus musculus) | 6480464 | aniline results in increased expression of PTPMT1 mRNA | CTD | PMID:22016648 | aristolochic acid A | increases expression | ISO | PTPMT1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of PTPMT1 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | decreases expression | ISO | PTPMT1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of PTPMT1 mRNA | CTD | PMID:26238291 | benzo[a]pyrene | increases methylation | ISO | PTPMT1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of PTPMT1 promoter | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | increases expression | ISO | PTPMT1 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PTPMT1 mRNA | CTD | PMID:25181051 | Brodifacoum | increases expression | EXP | | 6480464 | bromfenacoum results in increased expression of PTPMT1 protein | CTD | PMID:28903499 | carbon nanotube | decreases expression | ISO | Ptpmt1 (Mus musculus) | 6480464 | Nanotubes and Carbon results in decreased expression of PTPMT1 mRNA | CTD | PMID:25620056 | copper(II) sulfate | increases expression | ISO | PTPMT1 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of PTPMT1 mRNA | CTD | PMID:19549813 | dexamethasone | multiple interactions | ISO | PTPMT1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of PTPMT1 mRNA | CTD | PMID:28628672 | doxorubicin | increases expression | ISO | Ptpmt1 (Mus musculus) | 6480464 | Doxorubicin results in increased expression of PTPMT1 mRNA | CTD | PMID:22016648 | doxorubicin | affects expression | ISO | PTPMT1 (Homo sapiens) | 6480464 | Doxorubicin affects the expression of PTPMT1 mRNA | CTD | PMID:29803840 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of PTPMT1 mRNA | CTD | PMID:24136188 | indometacin | multiple interactions | ISO | PTPMT1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of PTPMT1 mRNA | CTD | PMID:28628672 | inulin | multiple interactions | ISO | Ptpmt1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of PTPMT1 mRNA | CTD | PMID:36331819 | ivermectin | decreases expression | ISO | PTPMT1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PTPMT1 protein | CTD | PMID:32959892 | lead(0) | affects splicing | ISO | PTPMT1 (Homo sapiens) | 6480464 | Lead affects the splicing of PTPMT1 mRNA | CTD | PMID:28903495 | methylmercury chloride | decreases expression | ISO | PTPMT1 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of PTPMT1 mRNA | CTD | PMID:28001369 | N-methyl-4-phenylpyridinium | increases expression | ISO | PTPMT1 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of PTPMT1 mRNA | CTD | PMID:24810058 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of PTPMT1 mRNA | CTD | PMID:24136188 | paracetamol | affects expression | ISO | Ptpmt1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of PTPMT1 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of PTPMT1 mRNA | CTD | PMID:33387578 | paracetamol | affects response to substance | ISO | PTPMT1 (Homo sapiens) | 6480464 | PTPMT1 gene polymorphism affects the susceptibility to Acetaminophen | CTD | PMID:26104854 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Ptpmt1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of PTPMT1 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of PTPMT1 mRNA | CTD | PMID:36331819 | phenacetin | increases expression | EXP | | 6480464 | Phenacetin results in increased expression of PTPMT1 mRNA | CTD | PMID:17698508 | phenylhydrazine | increases expression | EXP | | 6480464 | phenylhydrazine results in increased expression of PTPMT1 mRNA | CTD | PMID:17698508 | pirinixic acid | increases expression | ISO | Ptpmt1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of PTPMT1 mRNA | CTD | PMID:23811191 | potassium chromate | increases expression | ISO | PTPMT1 (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of PTPMT1 mRNA | CTD | PMID:22714537 | propiconazole | increases expression | ISO | Ptpmt1 (Mus musculus) | 6480464 | propiconazole results in increased expression of PTPMT1 mRNA | CTD | PMID:21278054 | quercetin | decreases expression | ISO | PTPMT1 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of PTPMT1 mRNA | CTD | PMID:21632981 | rac-lactic acid | decreases expression | ISO | PTPMT1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of PTPMT1 mRNA | CTD | PMID:30851411 | resveratrol | increases expression | ISO | Ptpmt1 (Mus musculus) | 6480464 | resveratrol results in increased expression of PTPMT1 protein | CTD | PMID:25505154 | rotenone | increases expression | ISO | Ptpmt1 (Mus musculus) | 6480464 | Rotenone results in increased expression of PTPMT1 mRNA | CTD | PMID:22016648 | sulfasalazine | increases expression | ISO | Ptpmt1 (Mus musculus) | 6480464 | Sulfasalazine results in increased expression of PTPMT1 mRNA | CTD | PMID:22016648 | sunitinib | increases expression | ISO | PTPMT1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of PTPMT1 mRNA | CTD | PMID:31533062 | temozolomide | increases expression | ISO | PTPMT1 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of PTPMT1 mRNA | CTD | PMID:31758290 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of PTPMT1 mRNA | CTD | PMID:16239168 | tetracycline | decreases expression | ISO | Ptpmt1 (Mus musculus) | 6480464 | Tetracycline results in decreased expression of PTPMT1 mRNA | CTD | PMID:16917069 | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of PTPMT1 gene | CTD | PMID:27618143 | tungsten | increases expression | ISO | Ptpmt1 (Mus musculus) | 6480464 | Tungsten results in increased expression of PTPMT1 mRNA | CTD | PMID:30912803 | tunicamycin | increases expression | ISO | PTPMT1 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of PTPMT1 mRNA | CTD | PMID:29453283 | valproic acid | affects expression | ISO | Ptpmt1 (Mus musculus) | 6480464 | Valproic Acid affects the expression of PTPMT1 mRNA | CTD | PMID:17292431 | |