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Gene: Casq1 (calsequestrin 1) Rattus norvegicus
Symbol: Casq1
Name: calsequestrin 1
RGD ID: 1586677
Description: Exhibits calcium ion binding activity. Involved in several processes, including regulation of sequestering of calcium ion; response to denervation involved in regulation of muscle adaptation; and skeletal muscle tissue development. Localizes to I band; T-tubule; and terminal cisterna lumen. Colocalizes with Golgi apparatus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human CASQ1 (calsequestrin 1); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Aspartactin; calsequestrin 1 (fast-twitch, skeletal muscle); calsequestrin, skeletal muscle isoform; Calsequestrin-1; Laminin-binding protein; LOC686019; similar to Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform)
Homo sapiens (human) : CASQ1 (calsequestrin 1)  HGNC  Alliance
Mus musculus (house mouse) : Casq1 (calsequestrin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Casq1 (calsequestrin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CASQ1 (calsequestrin 1)
Canis lupus familiaris (dog) : CASQ1 (calsequestrin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Casq1 (calsequestrin 1)
Sus scrofa (pig) : CASQ1 (calsequestrin 1)
Chlorocebus sabaeus (African green monkey) : CASQ1 (calsequestrin 1)
Heterocephalus glaber (naked mole-rat) : Casq1 (calsequestrin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01390,592,676 - 90,602,365 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1390,592,681 - 90,602,365 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01395,113,781 - 95,123,470 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41388,200,506 - 88,210,418 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1384,282,072 - 84,291,712 (-)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Casq1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1586677
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.